Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Natural+killer+%28NK%29+cell+receptor+KIR3DL1%2A004+is+sequestered+in+the+endoplasmic+reticulum+of+the+NK+cell+where+it+binds+to+the+chaperone+calreticulin+and+does+not+induce+the+unfolded+protein+response. assertion.
- assertion asSentence The+first+Ig+domain+of+KIR3DL1+contacts+MHC+class+I+at+a+secondary+site. assertion.
- assertion asSentence The+A52G+polymorphism+in+exon+3+and+the+frequencies+of+C32T+in+exon+9+of+KIR3DL2+gene+polymorphism+are+associated+with+the+pathogenesis+of+pre-eclampsia. assertion.
- assertion asSentence The+peptide+products+of+the+KiSS-1+gene+are+the+natural+ligands+of+the+G+protein-coupled+receptor%2C+GPR54+and+together+have+a+role+in+reproduction. assertion.
- assertion asSentence Kisspeptin+and+its+receptor+are+expressed+in+the+human%2C+rat+and+mouse+heart+and+kisspeptins+possess+potent+positive+inotropic+activity. assertion.
- assertion asSentence KISS1+and+KISS1R+expression+in+the+human+and+rat+carotid+body+and+superior+cervical+ganglion. assertion.
- assertion asSentence Germ+line+mutations+in+KISS1+and+KAI1+are+a+less+frequent+event+in+head+and+neck+cancer+patients. assertion.
- assertion asSentence High+KISS1+is+associated+with+central+precocious+puberty. assertion.
- assertion asSentence The+complexity+of+KIT+gene+mutations+and+chromosome+rearrangements+and+their+clinical+correlation+in+gastrointestinal+stromal+%28pacemaker+cell%29+tumors. assertion.
- assertion asSentence Mutations+of+c-KIT+causing+spontaneous+activation+of+the+KIT+receptor+kinase+are+associated+with+sporadic+adult+human+mastocytosis+%28SAHM%29+and+with+human+gastrointestinal+stromal+tumors. assertion.
- assertion asSentence Familial+gastrointestinal+stromal+tumors+and+mastocytosis+caused+by+a+germline+mutation+in+KIT. assertion.
- assertion asSentence The+KIT-phosphatidylinositol+3-kinase-Akt+protein+pathway+is+constitutively+activated+in+testicular+germ+cell+tumors%2C+due+to+overexpression+of+KIT+protein+and%2For+gain-of-function+mutations+in+the+c-kit+gene. assertion.
- assertion asSentence The+mutation+of+V604I+of+KIT+gene+is+the+cause+of+clinical+phenotype+of+the+family+with+piebaldism. assertion.
- assertion asSentence Gastric+gastrointestinal+stromal+tumors+have+a+lower+expression+of+KIT+compared+to+intestinal+GISTs. assertion.
- assertion asSentence The+occurrence+of+c-kit+mutations+in+gastrointestinal+stromal+tumors+also+correlates+with+patient%27s+age. assertion.
- assertion asSentence The+22-nt+c-kit87+promoter+sequence+possesses+distinctive+three-dimensional+structural+features+that+are+only+present+in+at+most+a+handful+of+other+genes. assertion.
- assertion asSentence Grb2+mediates+c-Kit+degradation+through+recruitment+of+Cbl+to+c-Kit%2C+leading+to+ubiquitination+of+c-Kit+followed+by+internalization+and+degradation. assertion.
- assertion asSentence Production+of+the+soluble+form+of+KIT%2C+s-KIT%2C+abolishes+stem+cell+factor-induced+melanogenesis+in+human+melanocytes. assertion.
- assertion asSentence There+is+a+high+expression+of+EGFR+and%2For+c-kit+in+basal-like+breast+carcinoma+in+this+series+from+Uganda+and+their+expression+is+associated+with+features+of+poor+prognosis. assertion.
- assertion asSentence Signaling+of+c-kit+in+dendritic+cells+influences+adaptive+immunity. assertion.
- assertion asSentence ABT-869+inhibits+proliferation+of+Ewing+sarcoma+cells+through+inhibition+of+PDGFRbeta+and+c-KIT+pathways. assertion.
- assertion asSentence Deletions+affecting+codons+557+and%2For+558+of+KIT+gene+is+associated+with+gastrointestinal+stromal+tumor. assertion.
- assertion asSentence Correlation+sduggested+between+KIT+expression+and+a+worse+prognosis+in+Merkel+cell+carcinoma+patients%2C+raising+the+possibility+of+an+active+role+of+this+receptor+in+tumor+progression+and+metastasis. assertion.
- assertion asSentence Regulation+of+bone+marrow+progenitor+cell+trafficking+by+stromal+cell-derived+factor+%28SDF%29-1+and+CXCR4+is+dependent+on+Src-mediated+c-kit+phosphorylation. assertion.
- assertion asSentence Small+gastrointestinal+stromal+tumors+%28GISTs%29+share+with+overt+GIST+KIT%2FPDGFRA+mutation. assertion.
- assertion asSentence Mutational+status+of+KIT+are+not+associated+with+primary+gastrointestinal+stromal+tumors. assertion.
- assertion asSentence Mutation+in+ABCC1+is+associated+with+mast-cell+leukemia. assertion.
- assertion asSentence Association+of+the+tissue+kallikrein+gene+promoter+with+ESRD+and+hypertension. assertion.
- assertion asSentence KLK1+gene+polymorphisms+are+not+associated+with+lupus+nephritis+in+a+Chinese+Han+population. assertion.
- assertion asSentence An+additional+serum+marker+for+the+detection+of+prostatic+cancer. assertion.
- assertion asSentence CD161+expression+on+human+CD8%2B+T+cells+defines+a+distinct+functional+subset+with+tissue-homing+properties. assertion.
- assertion asSentence CD94%2FNKG2A%2B+NK+cells+can+recognize+stressed+cells+in+a+peptide-dependent+manner. assertion.
- assertion asSentence HIV-1+infection+is+associated+with+higher+levels+NKG2A+in+the+cytotoxic+NK+subset+in+HIV-1-infected+patients+with+more+advanced+disease. assertion.
- assertion asSentence NKG2A+expression+is+inversely+correlated+with+the+number+of+coexpressed+killer+inhibitory+receptors+%28KIR%29+and+is+more+frequent+on+KIR3DL2-single+positive+natural+killer+cells. assertion.
- assertion asSentence CD94%2FNKG2A%2B+NK+cells+can+recognize+stressed+cells+in+a+peptide-dependent+manner. assertion.
- assertion asSentence Expression+of+the+inhibitory+NKR+%28CD94%2FNKG2A%29+of+the+G-CSF+mobilized+peripheral+blood+mononuclear+cells. assertion.
- assertion asSentence NKG2D+and+CD94+bind+to+heparin+and+sulfate-containing+polysaccharides. assertion.
- assertion asSentence Loss+of+CD94+is+associated+with+rheumatoid+arthritis. assertion.
- assertion asSentence Bradykinin+induces+IL-6+production+in+human+airway+smooth+muscle+cells. assertion.
- assertion asSentence Bradykinin+is+a+powerful+spasmogen+via+B%282%29+receptor+activation+in+the+normal+and%2C+especially%2C+in+the+inflamed+human+gallbladder. assertion.
- assertion asSentence ACE-I-induced+renoprotection%2C+in+the+context+of+macrophage-stimulated+mesangial+cell+scarring%2C+is+mediated%2C+at+least+in+part%2C+via+the+actions+of+bradykinin. assertion.
- assertion asSentence Bradykinin+enhances+the+migration+of+chondrosarcoma+cells+by+increasing+alpha2beta1+integrin+expression+through+the+BK+receptors%2FPLC%2FPKCdelta%2FNF-kappaB+signal+transduction+pathway. assertion.
- assertion asSentence KNG1+and+F11+are+the+main+genetic+regulators+of+plasma+FXI+level. assertion.
- assertion asSentence The+KLC1+56836CC+variant+exerts+a+significant+protective+effect+on+the+occurrence+of+multiple+sclerosis. assertion.
- assertion asSentence Phosphorylation+of+KLC1+at+serine+460+modulates+binding+and+trafficking+of+calsyntenin-1. assertion.
- assertion asSentence Binding+to+kinesin+I+ensures+properly+assembled+and+functioning+Kv3.1+channels+are+transported+into+axons. assertion.
- assertion asSentence Loop+L5+acts+as+a+conformational+latch+in+the+mitotic+kinesin+Eg5. assertion.
- assertion asSentence High+KIFC1+expression+is+associated+with+metastatic+spread+to+the+brain+in+primary+non-small+cell+lung+cancer. assertion.
- assertion asSentence %5Breview%5D+Recognition+and+shuttling+of+calcineurin+into+the+nucleus+by+importin-beta+requires+the+nuclear+localization+sequence+of+the+region+spanning+amino+acids+172-183+of+calcineurin+A+beta. assertion.
- assertion asSentence Overexpression+of+KPNA2+in+patients+with+epithelial+ovarian+cancer+is+positively+associated+with+an+epithelial+ovarian+cancer-specific+histologic+type+and+a+poor+prognosis. assertion.
- assertion asSentence KPNA2+expression+is+a+marker+for+progression+of+non-muscle-invasive+bladder+cancer+and+a+prognostic+marker+in+patients+undergoing+radical+cystectomy. assertion.
- assertion asSentence Impalpha3+is+an+HIV+integrase-interacting+cofactor+and+is+required+for+efficient+HIV-1+nuclear+import+and+replication. assertion.
- assertion asSentence The+interplay+of+the+two+negative+regulators%2C+transportin+and+importin+beta%2C+along+with+the+positive+regulator+RanGTP%2C+allows+precise+choreography+of+multiple+cell+cycle+assembly+events. assertion.
- assertion asSentence The+N-terminal+of+influenza+A+virus+PB1+mediates+its+binding+to+host+RanBP5. assertion.
- assertion asSentence Co-mutation+of+p53+and+K-ras+gene+has+neither+synergic+carcinogenesis-promoting+effect%2C+nor+prognostic+effect+on+rectal+cancer. assertion.
- assertion asSentence ANCA+selectively+activates+K-ras+during+induction+of+a+respiratory+burst+via+pathways+involving+multiple+upstream+kinases. assertion.
- assertion asSentence K-ras+mutations+occur+prominently+in+type+1+and+type+2+gastric+cancers. assertion.
- assertion asSentence The+role+of+K-ras+codon+12+and+codon+13+mutations+in+human+papillomavirus+virus-associated+colon+tumors. assertion.
- assertion asSentence Rna+silencing+of+K-ras%28V12%29+markedly+decreased+K-ras%28V12%29+gene+expression+and+inhibited+cellular+proliferation+of+lung+cancer+cells. assertion.
- assertion asSentence Circulating+KRAS+mutations+originate+from+tumors+and+are+prognostically+relevant+in+lung+cancer. assertion.
- assertion asSentence Overexpression+and+mutations+of+Kras+lead+to+common+altered+gene+expression+patterns+in+NIH3T3+cell. assertion.
- assertion asSentence KRAS2+mutations+in+human+pancreatic+acinar-ductal+metaplastic+lesions+are+limited+to+those+with+pancreatic+intraepithelial+neoplasia. assertion.
- assertion asSentence KRAS+mutations+are+associated+with+non-small+cell+lung+cancers. assertion.
- assertion asSentence KRAS+mutations+affect+tumor+necrosis+factor-induced+apoptosis+in+colon+carcinoma+cells+via+ERK-modulatory+negative+and+positive+feedback+circuits+along+with+non-ERK+pathway+effects. assertion.
- assertion asSentence Mutations+in+TP53%2C+KRAS%2C+or+EGFR+are+not+major+contributors+to+the+RCC+development+even+in+the+absence+of+VHL+inactivation. assertion.
- assertion asSentence Clinical+relevance+of+KRAS+in+human+cancers. assertion.
- assertion asSentence KRAS+mutations+arise+more+frequently+than+BRAF+mutations+in+Moroccan+patients+with+colorectal+carcinomas. assertion.
- assertion asSentence KRAS+mutation+is+associated+with+treatment+response+for+metastatic+colorectal+cancer. assertion.
- assertion asSentence Alterations+of+the+KRAS+gene+is+associated+with+myelodysplastic+syndromes+and+acute+myeloid+leukemia. assertion.
- assertion asSentence KRAS+mutation+is+associated+with+nonsmall+cell+lung+cancer. assertion.
- assertion asSentence KRAS+mutation+is+an+early+hit+in+lung+adenocarcinoma+development. assertion.
- assertion asSentence KRAS+mutations+are+associated+with+treatment+response+in+non-small+cell+lung+cancer. assertion.
- assertion asSentence APC+and+KRAS+mutations+in+distal+colorectal+polyps+are+related+to+smoking+habits+in+men. assertion.
- assertion asSentence Mutations+detected+in+KRAS+in+microdissected+samples+from+different+areas+of+the+same+tumor+%28colon+cancer%29+differed+according+to+immunophenotype. assertion.
- assertion asSentence KRAS+mutation+is+associated+with+colorectal+serrated+adenocarcinoma. assertion.
- assertion asSentence MSP58+activates+the+DNA+damage+response+and+p53%2Fp21+signaling+pathways. assertion.
- assertion asSentence An+acetylation-mimetic+mutation+in+K-RAS4B+suppressed+guanine+nucleotide+exchange+factor-induced+nucleotide+exchange+and+inhibited+in+vitro+transforming+activity. assertion.
- assertion asSentence Missence+mutation+is+a+causse+of+epidermolysis+bullosa+simplex+in+a+3-year+old+boy. assertion.
- assertion asSentence CK5%2F6+and%2For+EGFR+expressing+tumor+types+have+a+persistently+poorer+prognosis+over+the+longer+term. assertion.
- assertion asSentence Positive+expression+of+CK5%2F6+or+CK17+in+patients+with+triple-negative+breast+cancer+is+correlated+with+poor+prognosis%2C+high+grade+differentiation+and+axillary+lymph+node+metastasis. assertion.
- assertion asSentence CK5%2F6+and%2For+EGFR+expressing+tumor+types+have+a+persistently+poorer+prognosis+over+the+longer+term. assertion.
- assertion asSentence The+combined+expression+of+CK7+and+CK20+has+a+low+specificity+in+the+distinction+between+esophageal+and+cardiac+%28stomach%29+adenocarcinomas. assertion.
- assertion asSentence Alteration+of+CK7+and+CK20+expression+profile+that+occurs+early+in+small+intestinal+tumorigenesis. assertion.
- assertion asSentence Both+the+CK7-%2FCK20%2B+phenotype+and+expression+of+the+antibody+CDX2+are+highly+specific+and+sensitive+markers+of+colorectal+origin. assertion.
- assertion asSentence Cancer-associated+cleavage+of+cytokeratin+8%2F18+heterotypic+complexes+exposes+a+neoepitope+in+human+adenocarcinomas. assertion.
- assertion asSentence Invasive+ductal+carcinomas+of+the+breast+align+with+the+KRT8%2F18+staining+phenotypes. assertion.
- assertion asSentence Clumping+factor+B+is+capable+of+binding+cytokeratin+8+during+infection. assertion.
- assertion asSentence Mild+recessive+bullous+congenital+ichthyosiform+erythroderma+due+to+a+previously+unidentified+homozygous+keratin+10+nonsense+mutation. assertion.
- assertion asSentence Pneumococcal+ligands+K10%2C+laminin+receptor+and+platelet-activating+factor+receptor+are+elevated+in+aged+lungs+and+contribute+to+the+enhanced+susceptibility+to+pneumonia. assertion.
- assertion asSentence Metaplastic+squamous+cells+differentiate+with+a+decrease+of+CK18+and+an+increase+of+CK13+expression. assertion.
- assertion asSentence CK13+expression+is+elevated+in+KB+cells+treated+with+all-trans+retinoic+acid+or+arsenic+trioxide. assertion.
- assertion asSentence Antikeratin+16+autoAbs+are+involved+in+psoriasis%2C+by+exaggerating+the+innate+immune+response+of+keratinocytes. assertion.
- assertion asSentence KRT17+is+upregulated+in+gastric+adenocarcinoma+and+is+associated+with+tumor+progression. assertion.
- assertion asSentence Cancer-associated+cleavage+of+cytokeratin+8%2F18+heterotypic+complexes+exposes+a+neoepitope+in+human+adenocarcinomas. assertion.
- assertion asSentence Keratin+hyperphosphorylation+on+most+K8%2F18+sites+in+all+cirrhotic+liver+explants+tested+and+in+most+liver+biopsies+from+patients+with+chronic+hepatitis+C. assertion.
- assertion asSentence Keratin+18+%28K18%29+expression+in+tumor+cells+is+associated+with+reduced+invasiveness+in+vitro. assertion.
- assertion asSentence Serum+levels+of+the+apoptotic+marker+cytokeratin+18%2FM30+peak+at+24+h+after+acute+myocardial+infarction+and+reflects+the+extent+of+coronary+artery+disease+in+this+patient+group. assertion.
- assertion asSentence CK19+is+consistently+expressed+in+the+epithelial+cells+of+pancreatic+ducts. assertion.
- assertion asSentence CK19+modulates+ER+stress+signaling+and+contributes+to+cell+survival+and+dormancy+in+breast+cancer+cells. assertion.
- assertion asSentence The+kinesin-1+deficiency+weakened+intercellular+adhesion%2C+despite+the+maintenance+of+adherens+junctions+and+other+desmosome+components+at+the+plasma+membrane. assertion.