Nanopublications

Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }

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NP395483.RAdivgogmsDN6EqH6K7mFwkFZO4lRR-q7TMm9E0895Sos130_assertion description "[These models have been designed to address key questions including: (1) whether NF1 loss in the Schwann cell lineage is essential for tumorigenesis; (2) what cell type(s) in the Schwann cell lineage gives rise to dermal neurofibromas, plexiform neurofibromas and MPNSTs; (3) how the tumor microenvironment contributes to neoplasia; (4) what additional mutations contribute to neurofibroma-MPNST progression; (5) what role different neurofibromin-regulated Ras proteins play in this process and (6) how dysregulated growth factor signaling facilitates PNS tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395483.RAdivgogmsDN6EqH6K7mFwkFZO4lRR-q7TMm9E0895Sos130_provenance.
NP395486.RAdvWjI_W942EAUGLqv_5CaH85dCLBUiPEnef2pSuD2Z8130_assertion description "[These data suggest that the target of deletion in glioblastoma multiforme includes both p15 and p16 genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395486.RAdvWjI_W942EAUGLqv_5CaH85dCLBUiPEnef2pSuD2Z8130_provenance.
NP395490.RAWxNMWpJ7T2QLCcebJW_k8WnwftbG4Xddd31TywyBzaw130_assertion description "[Loss of GSTP1 function also appears to be characteristic of prostatic epithelial neoplasia (PIN) lesions, thought to represent PCA precursors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395490.RAWxNMWpJ7T2QLCcebJW_k8WnwftbG4Xddd31TywyBzaw130_provenance.
NP395494.RAar_PRUfmbOM0BIKyZpfDS_LMhNp55GaE6vM1MB95XLU130_assertion description "[We evaluated the prevalence of the 2 most common genetic risk factors for thromboembolism, factor V Leiden (G1691A) and prothrombin G20210A, in young PFO patients who were referred for percutaneous transcatheter closure of their PFO.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395494.RAar_PRUfmbOM0BIKyZpfDS_LMhNp55GaE6vM1MB95XLU130_provenance.
NP395503.RATyrZ2karwPOJH0A10WiHEocSoikvg5t8O15Fspzdz38130_assertion description "[Here, we report that male mice deficient in PICK1 are infertile and have a phenotype resembling the human disease globozoospermia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395503.RATyrZ2karwPOJH0A10WiHEocSoikvg5t8O15Fspzdz38130_provenance.
NP395504.RAR26fGuWMoH9IgG8Xh9XeGRpPKH_g4tu5-IrNvLCNxvY130_assertion description "[However, the significance of the 4G/5G polymorphism of the PAI-I gene in the pathogenesis of ischemic heart diseases has not been determined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395504.RAR26fGuWMoH9IgG8Xh9XeGRpPKH_g4tu5-IrNvLCNxvY130_provenance.
NP395511.RAcY1w65PnxUWs8LoZqgy9hrl9-emwr9czl2I8KvbzwFk130_assertion description "[However, RA and OA FLS produced significantly greater levels of MCP-1 following stimulation by IL-2 and IL-1 beta; RA FLS produced significantly more MCP-1 than OA FLS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395511.RAcY1w65PnxUWs8LoZqgy9hrl9-emwr9czl2I8KvbzwFk130_provenance.
NP395512.RAd1pTNWJn9NGV5pJZlC8BnPjbQls0dEUjtaFeU3z_g3I130_assertion description "[A selective estrogen receptor-beta agonist causes lesion regression in an experimentally induced model of endometriosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395512.RAd1pTNWJn9NGV5pJZlC8BnPjbQls0dEUjtaFeU3z_g3I130_provenance.
NP395515.RAcGIhMPbKWk9TPdIXKiKFZWWqtyPnvnUtRklzoZkUUiY130_assertion description "[(1) Pauciarticular JA with late onset and a strong male proponderance is associated with HLA-B27 and represents the group of juvenile spondyloarthropathies related to adult ankylosing spondylitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395515.RAcGIhMPbKWk9TPdIXKiKFZWWqtyPnvnUtRklzoZkUUiY130_provenance.
NP395519.RAV5xOuDaOqhg4AA2E3H7CL4rtDdaILUckTJe_q_n9XjM130_assertion description "[Fibroblasts cultured from the skin of the affected dogs accumulated excessive 35S-labeled mucopolysaccharide; this accumulation could be decreased to a normal level by exogenous human high-uptake alpha-L-iduronidase (Hurler corrective factor) as well as by secretions of normal human or canine fibroblasts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395519.RAV5xOuDaOqhg4AA2E3H7CL4rtDdaILUckTJe_q_n9XjM130_provenance.
NP395522.RAZcxscBdHYYwVjQ2GedcvGhYVwfmKTsZvagtgKCjD-eI130_assertion description "[However, the biochemical function of merlin and the effector pathways critical for the pathogenesis of malignant mesothelioma and other NF2-related malignancies are not known.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395522.RAZcxscBdHYYwVjQ2GedcvGhYVwfmKTsZvagtgKCjD-eI130_provenance.
NP395532.RAfsZ7PYCXc8NWCjViTMwoJ7oL6x1vvb39dYJ7NG4Kl3Q130_assertion description "[Our findings suggest that in human pancreatic cancer cells, Cldn18 is primarily regulated at the transcriptional level via specific PKC signaling pathways and modified by DNA methylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395532.RAfsZ7PYCXc8NWCjViTMwoJ7oL6x1vvb39dYJ7NG4Kl3Q130_provenance.
NP395534.RAWhoaI-6g5SCsTygeV4wYnmELncfHlzPDBS52TB7IYHk130_assertion description "[Research on signaling pathways dysregulated in lung cancer is ongoing, including investigation of the hepatocyte growth factor receptor (HGFR) or c-Met.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395534.RAWhoaI-6g5SCsTygeV4wYnmELncfHlzPDBS52TB7IYHk130_provenance.
NP395536.RARdj0VxuwhWmSYNfTjzLtzjBQPUiB5q99a5qBksRSPQ0130_assertion description "[We report here 4 cases of ABL with a t(X;6)(p11;q23) translocation occurring in male infants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395536.RARdj0VxuwhWmSYNfTjzLtzjBQPUiB5q99a5qBksRSPQ0130_provenance.
NP395545.RAd--1Q4RNEO94eYCOo49nVo3V-2j-bqcbO8Ee6zd_Lb4130_assertion description "[T-cell leukemia/lymphoma 1 (TCL1) is an oncogene overexpressed in T-cell prolymphocytic leukemia and in B-cell malignancies including B-cell chronic lymphocytic leukemia and lymphomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395545.RAd--1Q4RNEO94eYCOo49nVo3V-2j-bqcbO8Ee6zd_Lb4130_provenance.
NP395549.RAffF71iddA8gxx_TZztcY9OUZJuIt8Cuk0wMD0bJt_eE130_assertion description "[Frequencies of methylation in GCTs were 40% for p16 and ER-alpha; 36% for BRCA1 and RASSF1A; 28% for hMLH1; 24% for TIMP3, Twist, and GSTP1; and 20% in TMS1 and AR.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395549.RAffF71iddA8gxx_TZztcY9OUZJuIt8Cuk0wMD0bJt_eE130_provenance.
NP395555.RARlfGWOrVN080usbiTrXbOexwVKf5gFGgRHYj9POfnd0130_assertion description "[Overall, these results suggest that γ-tocotrienol is a novel blocker of the STAT3 activation pathway, with a potential role in future therapies for HCC and other cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395555.RARlfGWOrVN080usbiTrXbOexwVKf5gFGgRHYj9POfnd0130_provenance.
NP395559.RAYCunEbmlF5KEH67Py_rJr4Fd-heDZlCgFTA9HWF25X0130_assertion description "[Salla disease (SD) and infantile sialic acid storage disease (ISSD) are recessively inherited, neuro-degenerative disorders caused by mutations in the SLC17A5 gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395559.RAYCunEbmlF5KEH67Py_rJr4Fd-heDZlCgFTA9HWF25X0130_provenance.
NP395561.RAUt4jNzWMumZBedalYaAksNuU_kXTmW63y4klRDFYX0E130_assertion description "[TBK1 silencing decreased expression of epithelial markers and increased expression of mesenchymal markers in ERα-positive breast cancer cells, enhancing tumor growth and lung metastasis in vivo in a manner associated with downregulation of ERα expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395561.RAUt4jNzWMumZBedalYaAksNuU_kXTmW63y4klRDFYX0E130_provenance.
NP395572.RAf03Rk18SxzktNlG7ZUoFOdXc7Wx0lZfAHm3WB44e87c130_assertion description "[Elevated immunoglobulin E against recombinant Brugia malayi gamma-glutamyl transpeptidase in patients with bancroftian filariasis: association with tropical pulmonary eosinophilia or putative immunity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395572.RAf03Rk18SxzktNlG7ZUoFOdXc7Wx0lZfAHm3WB44e87c130_provenance.
NP395578.RAXMwETafSsi7FzghPZrkR19LWi1hp1iBgHXy9IhB8wfQ130_assertion description "[Associations were observed between the risk of endometrial cancer and genotypes of the following steroid hormone metabolism genes: CYP1A1*2C (adjusted odds ratio [OR] = 1.68, 95% confidence interval [CI] = 1.08 to 2.61); SULT1A1*3 (adjusted OR = 0.51, 95% CI = 0.29 to 0.92); and the G --> A variant in the promoter of SULT1E1 at position -64 (adjusted OR = 1.45, 95% CI = 1.06 to 1.99).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395578.RAXMwETafSsi7FzghPZrkR19LWi1hp1iBgHXy9IhB8wfQ130_provenance.
NP395580.RARhCV1UVlP8Qho1pH2ih3H3NasL0zsYK70wySUZcx3WU130_assertion description "[The gene encoding a novel transporter, the breast cancer resistance protein (BCRP), was recently found to be overexpressed in a mitoxantrone-selected human colon cell line, S1-M1-3.2, which was used to identify FTC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395580.RARhCV1UVlP8Qho1pH2ih3H3NasL0zsYK70wySUZcx3WU130_provenance.
NP395584.RAdzX1WCCS_YIrjDDs3Telhv9k9w-APKHlfY0z8F2yx9Q130_assertion description "[In conclusion, MTDH expression is high in cervical cancer, and it contributes to chemoresistance of cervical cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395584.RAdzX1WCCS_YIrjDDs3Telhv9k9w-APKHlfY0z8F2yx9Q130_provenance.
NP395587.RAdD4xPoZOTrdGVaCjP_aVTGuT_29-sR_RAHXe7Uc-nPE130_assertion description "[Protein C and protein S deficiencies increase the risk of venous thrombosis and pulmonary embolism, but their role in arterial thrombosis or embolism is controversial.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395587.RAdD4xPoZOTrdGVaCjP_aVTGuT_29-sR_RAHXe7Uc-nPE130_provenance.
NP395592.RAaKeT1yaCBoE5t3wntLCFAAhD7V7uOhilRc05txFVrog130_assertion description "[Recent studies have highlighted the fact that WWOX acts as a tumor suppressor factor in various malignant tumors, including gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395592.RAaKeT1yaCBoE5t3wntLCFAAhD7V7uOhilRc05txFVrog130_provenance.
NP395600.RAf37ai-wlPFlYLtEUbFKOqeoOOqL43-NQJt8HQqQrbf4130_assertion description "[Factor VIII inhibitor developed in a 60-year-old patient with mild hemophilia A after surgery for colon cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395600.RAf37ai-wlPFlYLtEUbFKOqeoOOqL43-NQJt8HQqQrbf4130_provenance.
NP395601.RAcjVFm0y3Svz2o8gTEhphVdCLzbaPJE7EOyBOAfmIFtI130_assertion description "[Heterozygous mutations in PKD1 or PKD2, which encode polycystin-1 (PC1) and polycystin-2 (PC2), respectively, cause autosomal dominant PKD (ADPKD), whereas mutations in PKHD1, which encodes fibrocystin/polyductin (FPC), cause autosomal recessive PKD (ARPKD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395601.RAcjVFm0y3Svz2o8gTEhphVdCLzbaPJE7EOyBOAfmIFtI130_provenance.
NP395604.RAe6zkcKrA4UcRnlvs9yA99m87d0hx_pxION7LKK5Gmlo130_assertion description "[The underlying causes of the DM1 and CMTX1 are mutations in the DMPK and GJB1 gene, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395604.RAe6zkcKrA4UcRnlvs9yA99m87d0hx_pxION7LKK5Gmlo130_provenance.
NP395611.RAawwfokztjblG756QFlrLTueKcv-NQ8grfPXWk8RyD7Q130_assertion description "[RHOU, MAP3K11 and WASF3 gene copy numbers were changed in the subset of leiomyomas with submicroscopic aberrations, and these genes have previously been implicated in tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395611.RAawwfokztjblG756QFlrLTueKcv-NQ8grfPXWk8RyD7Q130_provenance.
NP395612.RAdk8LfTHTmDm6CRZT9swXrFsXlItdqSHYmcPPd500AOM130_assertion description "[Long-term reconstitution of MPL W515 CD34(+) cells in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice was successful for as long as 12 weeks after transplantation, indicating that MPL W515 mutations were present in HSCs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395612.RAdk8LfTHTmDm6CRZT9swXrFsXlItdqSHYmcPPd500AOM130_provenance.
NP395615.RAT53vc0aApanJ_hkhLOd4HojbbAtCUH1B6TI390HYrcU130_assertion description "[Biallelic mutations of BRCA2 are a cause of Fanconi anemia and characteristic childhood cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395615.RAT53vc0aApanJ_hkhLOd4HojbbAtCUH1B6TI390HYrcU130_provenance.
NP395628.RAapjCm0O1p2m_9s_CbdbFnO3a2vP3ypbe7LJTzi7zQsU130_assertion description "[Taken together, these results identify ILK-regulated signaling as a broadly adaptive hypertrophic response mechanism relevant to a wide range of clinical heart disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395628.RAapjCm0O1p2m_9s_CbdbFnO3a2vP3ypbe7LJTzi7zQsU130_provenance.
NP395633.RAf85X1Qlr8uFW_ZGeDSoPKGzqnOY8SRbaWJeTQYeJZ6A130_assertion description "[These data suggest that genetic variation at the ESR2 locus may be associated with some determinants of blood pressure, and that there is a possible involvement of this polymorphism in causing hypertension in Japanese women.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395633.RAf85X1Qlr8uFW_ZGeDSoPKGzqnOY8SRbaWJeTQYeJZ6A130_provenance.
NP395636.RAWMtxLUETaVbcyWwd7zHigDhxI7ldGdvR8ZIpVXC4pLs130_assertion description "[Recessive loss-of-function mutations in the surfactant protein-B and the ATP-binding cassette family member A3 (ABCA3) genes present as lethal surfactant deficiency in the newborn, whereas other recessive mutations in ABCA3 and dominant mutations in the surfactant protein-C gene result in interstitial lung disease in older infants and children.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395636.RAWMtxLUETaVbcyWwd7zHigDhxI7ldGdvR8ZIpVXC4pLs130_provenance.
NP395638.RASluHYTEQd7pMjEmpjm63YklxemMYVXLJmIAEtwfz5_I130_assertion description "[Evidence for autocrine growth stimulation by a gastrin/CCK-like peptide of the gastric cancer HGT-1 cell line.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395638.RASluHYTEQd7pMjEmpjm63YklxemMYVXLJmIAEtwfz5_I130_provenance.
NP395639.RAY3q5sRlI00W3S2Jg_aDoOi0lziS6DhpKFPOJn3131t8130_assertion description "[Transcript levels of PAR-2, TPH-1 and 5-HT(3) receptor subunits did not differ between IBS and HS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395639.RAY3q5sRlI00W3S2Jg_aDoOi0lziS6DhpKFPOJn3131t8130_provenance.
NP395649.RAcX2YDfEBy1-ekWU-WqV9CtS3Nr6Vfzp591s8hDixtl4130_assertion description "[The levels of miR-10b and miR-21 are found significantly increased in the CSF of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395649.RAcX2YDfEBy1-ekWU-WqV9CtS3Nr6Vfzp591s8hDixtl4130_provenance.
NP395652.RAYO9Rs-RkAAmjQ61kUa8Q8jm-zIO9CDmY7U-OaIySJXI130_assertion description "[Although no association of any CYP3A4 polymorphisms and breast cancer has been documented, the CYP3A4*1B (392A>G) variant, correlates with earlier menarche and endometrial cancer secondary to tamoxifen therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395652.RAYO9Rs-RkAAmjQ61kUa8Q8jm-zIO9CDmY7U-OaIySJXI130_provenance.
NP395668.RATgg9U_az2gYLqsJKwEnuDPviJZQUGSP40pCMOyeAhnw130_assertion description "[These results suggest that FST plays a critical role in the production of multiple-organ metastasis, predominantly by inhibiting the angiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395668.RATgg9U_az2gYLqsJKwEnuDPviJZQUGSP40pCMOyeAhnw130_provenance.
NP395671.RAVwIUIQd6IdVJYzdmEaMR3QyXmnb3dkiyvKDBoCQxGaI130_assertion description "[Cyclin-dependent kinase 5 (Cdk5) is known to regulate prostate cancer metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395671.RAVwIUIQd6IdVJYzdmEaMR3QyXmnb3dkiyvKDBoCQxGaI130_provenance.
NP395672.RAewOa0Lv-ndqO9jOE9vWxL8INncIlruayrU8oRHTDYvQ130_assertion description "[Future studies of MBL should be directed towards determining its relationship to clinical disease, particularly in individuals from families with a genetic predisposition to developing CLL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395672.RAewOa0Lv-ndqO9jOE9vWxL8INncIlruayrU8oRHTDYvQ130_provenance.
NP395685.RAfKIgY3ZqDDUN1l_TuNJzJ2QcXdb0_Kp8-y9GVT9rPjc130_assertion description "[A child with respiratory failure and cor pulmonale secondary to the obesity hypoventilation syndrome (OHS) was found to have abnormal beta-endorphin levels in cerebrospinal fluid (CSF) and serum.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395685.RAfKIgY3ZqDDUN1l_TuNJzJ2QcXdb0_Kp8-y9GVT9rPjc130_provenance.
NP395692.RAbgV6Clz9VnfM82fB0thaGrPj2uaxUxaZptF99E3b28I130_assertion description "[SCA2 and SCA3 mutations in young-onset dopa-responsive parkinsonism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395692.RAbgV6Clz9VnfM82fB0thaGrPj2uaxUxaZptF99E3b28I130_provenance.
NP395701.RAXTbM9vk6-8oQOF--P8UZbyaBkbA_dKV4B2BCDXLmY18130_assertion description "[Interestingly, PS2V-encoding protein was expressed in neuropathologically affected neurons of the hippocampal CA1 region and temporal cortex in AD patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395701.RAXTbM9vk6-8oQOF--P8UZbyaBkbA_dKV4B2BCDXLmY18130_provenance.
NP395705.RAejoyTDhGryg_NM8wY4J79wAyyOmZBDvX3XKBNGqPoBU130_assertion description "[Sequenom MassARRAY identified PIK3CA mutations restricted to the DCIS component in two cases, and in a third case the frequency of the PIK3CA mutant allele reduced from 49% in the DCIS to 25% in the IDC component.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395705.RAejoyTDhGryg_NM8wY4J79wAyyOmZBDvX3XKBNGqPoBU130_provenance.
NP395708.RAfkaktc20PPWqj6MvTQgHN5GlPiPSb_0MSfxEr6SHNxM130_assertion description "[A balanced de novo (X;9) translocation was observed in a patient with progressive muscular dystrophy of Duchenne's type (DMD), Turner's syndrome, epilepsy and mental retardation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395708.RAfkaktc20PPWqj6MvTQgHN5GlPiPSb_0MSfxEr6SHNxM130_provenance.
NP395709.RAXKOIHRoW6p1L2uk5VOiklANNe0XbUSqi3r6CzVCmK3Y130_assertion description "[Elevated SIRs were found mainly for female breast cancer (39.1, 95% CI 24.8 to 58.6), thyroid cancer in women (43.2, 95% CI 19.7 to 82.1) and in men (199.5, 95% CI 106.39 to 342.03), melanoma in women (28.3, 95% CI 7.6 to 35.4) and in men (39.4, 95% CI 10.6 to 100.9), and endometrial cancer (48.7, 95% CI 9.8 to 142.3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395709.RAXKOIHRoW6p1L2uk5VOiklANNe0XbUSqi3r6CzVCmK3Y130_provenance.
NP395710.RAVRwaRSd8OsBZHjw9WIZMEobadiz6-2aCta9YGHv0DqY130_assertion description "[Hypoxia-inducible factor 1 (HIF-1) plays essential roles in tumor angiogenesis and growth by regulating the transcription of several key genes in response to hypoxic stress and growth factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395710.RAVRwaRSd8OsBZHjw9WIZMEobadiz6-2aCta9YGHv0DqY130_provenance.
NP395712.RAV-zdhuER3fXJTdVW6lV5e0vjBeJG0NU4R9ZcNb3PJIs130_assertion description "[MIB-1 labeling index (LI) of >2% often heralds poor prognosis and tumour recurrence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395712.RAV-zdhuER3fXJTdVW6lV5e0vjBeJG0NU4R9ZcNb3PJIs130_provenance.
NP395715.RAQDzwJPBzkP5gS_4JmFnwCv0H1kO3QWvX6n-T8mq4unU130_assertion description "[Finally, AzaC treatment of mice that received a transplant of major histocompatibility complex mismatched allogeneic bone marrow and T cells mitigates GVHD while preserving GVL by peripheral conversion of alloreactive effector T cells into FOXP3(+) Tregs and epigenetic modulation of genes downstream of Foxp3 required for the suppressor function of Tregs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395715.RAQDzwJPBzkP5gS_4JmFnwCv0H1kO3QWvX6n-T8mq4unU130_provenance.
NP395716.RAe8oC4ErX3IPW0opi92FPsDSYPb3CgzmlRo9aGY7qiPI130_assertion description "[Variables with the greatest prognostic discrimination were the presence of another ipsilobar nodule and tumour size > 3 cm, followed by other anatomical and clinical factors, and molecular expressions of phosphorylated mammalian target of rapamycin (phospho-mTOR), Ki67cell proliferation index and phosphorylated acetyl-coenzyme A carboxylase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395716.RAe8oC4ErX3IPW0opi92FPsDSYPb3CgzmlRo9aGY7qiPI130_provenance.
NP395717.RAag5noyCmWzAuPoqLnAl7-Oo4JqxFx1wdHH-uKCepRVM130_assertion description "[Hepatic function was assessed by evaluating the following parameters: liver histology; plasma levels of alanine aminotransferase (ALT), triglyceride (TG), malondialdehyde (MDA), and reduced glutathione (GSH); expression levels of TNF-α and IL-6; and levels of caspase-3 and pJNK/JNK protein.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395717.RAag5noyCmWzAuPoqLnAl7-Oo4JqxFx1wdHH-uKCepRVM130_provenance.
NP395719.RAdzSxZWWzsUm0ml_A5JTaWKcqXai7Pw09ooDuFuk7s0Q130_assertion description "[A new form of acute hepatic porphyria with double genetic defect--deficiency of porphobilinogen deaminase and coproporphyrinogen oxidase--is described.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395719.RAdzSxZWWzsUm0ml_A5JTaWKcqXai7Pw09ooDuFuk7s0Q130_provenance.
NP395726.RAfmKLiBV9BR-48zhonKuqLD77o3LiVOIYNyKh_wUDzH0130_assertion description "[Localization of the syndactyly type II (synpolydactyly) locus to 2q31 region and identification of tight linkage to HOXD8 intragenic marker.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395726.RAfmKLiBV9BR-48zhonKuqLD77o3LiVOIYNyKh_wUDzH0130_provenance.
NP395730.RAZV4OOo6C34PNMKSs6MGiF9jKodWBhWe795kyVH3RakY130_assertion description "[We resequenced the coding region, flanking intronic, and proximal promoter regions of the lamin a/c gene in 43 women with PCOS with evidence of upper-body obesity (waist circumference >88 cm) and identified 56 variants, two of which were nonsynonymous substitutions (lmna11 exon1 E98D; lmna24 exon 7 R455C).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395730.RAZV4OOo6C34PNMKSs6MGiF9jKodWBhWe795kyVH3RakY130_provenance.
NP395731.RAdnBgo2bIQnjqRg1_8EbU3Cu4deCGQTVtHt1LdQQQAeo130_assertion description "[However, little is known about the role of Nuclear factor kB (NF-kB) activity-dependent P-selectin in ox-LDL-induced foam cell formation during atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395731.RAdnBgo2bIQnjqRg1_8EbU3Cu4deCGQTVtHt1LdQQQAeo130_provenance.
NP395732.RAfBB_pmiim3begLEvyFBPZx974Xvv2v3r7UotE5hwpSs130_assertion description "[Enhanced levels of wild-type versus mutant thyroid hormone receptor beta 1 messenger RNA in fibroblasts from heterozygotes of kindred S with thyroid hormone resistance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395732.RAfBB_pmiim3begLEvyFBPZx974Xvv2v3r7UotE5hwpSs130_provenance.
NP395734.RAfLK3QIuJqzMl7Sj6V1I46Dn9wxMx3vvXG4JMikVGPLk130_assertion description "[For the first two subgroups, aberrations of the HMGIC and HMGIY genes have been described and are held responsible for tumor initiation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395734.RAfLK3QIuJqzMl7Sj6V1I46Dn9wxMx3vvXG4JMikVGPLk130_provenance.
NP395736.RAVT0mkskvpJjxpLYqC1CAe9zLd_5uLfAFsVBbt1yl3TA130_assertion description "[We used a standard 96-well microplate with a single PCR condition in an adaptation of the SCAIP (single-condition amplification with internal primer) method to sequence the HFE (hemochromatosis), HAMP (hepcidin antimicrobial peptide), HFE2/HJV [hemochromatosis type 2 (juvenile)], SLC40A1 (ferroportin), and TFR2 (transferrin receptor 2) genes, and the 5' untranslated region of the FTL (ferritin, light polypeptide) gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395736.RAVT0mkskvpJjxpLYqC1CAe9zLd_5uLfAFsVBbt1yl3TA130_provenance.
NP395740.RAcfPyZ7y_KmMLUJqj5Pe8TJi3g123uG1wokZyzDx7Kf0130_assertion description "[Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395740.RAcfPyZ7y_KmMLUJqj5Pe8TJi3g123uG1wokZyzDx7Kf0130_provenance.
NP395743.RAQVyyD6DrRNxJMCTyr0OCbh4cdEJKVBUIEI3yWSpBoGI130_assertion description "[To investigate its possible involvement in Zellweger syndrome (ZS), an inborn error of peroxisome assembly, we cloned and sequenced cDNAs for human PMP70 and mapped the gene to chromosome 1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395743.RAQVyyD6DrRNxJMCTyr0OCbh4cdEJKVBUIEI3yWSpBoGI130_provenance.
NP395744.RAYq8Fu52QMVJurTVmkxOjp2o9VZrD4s7pcikmsfKpaso130_assertion description "[A previously reported family with amyloid polyneuropathy (FAP) was reinvestigated to determine the type of mutation in the transthyretin (prealbumin) molecule.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395744.RAYq8Fu52QMVJurTVmkxOjp2o9VZrD4s7pcikmsfKpaso130_provenance.
NP395748.RAaQ_RljF3Xr3okFwLvz6S6RmiNQbIXCcj-0KbdPGyfic130_assertion description "[Dysplasia was graded in 212 biopsy sets taken during follow-up upper endoscopy in 27 patients in whom ultimately high-grade dysplasia (HGD) or EAC was detected.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395748.RAaQ_RljF3Xr3okFwLvz6S6RmiNQbIXCcj-0KbdPGyfic130_provenance.
NP395750.RATjzkPmrGiIF6KFOKEopNj11aK5tQr_bC78LrQ7FvmYc130_assertion description "[We recently demonstrated that RASSF1A, a new tumour-suppressor gene located at 3p21.3 is frequently inactivated by promoter region hypermethylation in a variety of human cancers including lung, breast, kidney and neuroblastoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395750.RATjzkPmrGiIF6KFOKEopNj11aK5tQr_bC78LrQ7FvmYc130_provenance.
NP395751.RAQjqd4Q2xIhjcigwF96K3R5E06kclxY-XEQqrUCv5bAE130_assertion description "[Furthermore, one SP-A2 allele (1A0) shown to associate with low SP-A mRNA levels is found with higher frequency in a subgroup with respiratory distress syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395751.RAQjqd4Q2xIhjcigwF96K3R5E06kclxY-XEQqrUCv5bAE130_provenance.
NP395755.RAbvRm7DajGPi2V4hdskAtdCYX4xRkG_oWe47Z7xE-P_o130_assertion description "[Here, we show that naturally occurring IDE missense mutations in a well-characterized rat model of type 2 diabetes mellitus (DM2) result in decreased catalytic efficiency and a significant approximately 15 to 30% deficit in the degradation of both insulin and Abeta.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395755.RAbvRm7DajGPi2V4hdskAtdCYX4xRkG_oWe47Z7xE-P_o130_provenance.
NP395756.RAYwLk9AIdWSNWRMx6s9aLbHU5m1u8PteJCi-njpGYD1k130_assertion description "[Two known DSAP loci, DSAP1 and DSAP2, two DSAP candidate genes (SART3 and SSH1), one DSP-linked locus and one PPPD-linked locus were first excluded in the family.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395756.RAYwLk9AIdWSNWRMx6s9aLbHU5m1u8PteJCi-njpGYD1k130_provenance.
NP395760.RAe78H-UPFMHZspbGIwXd3aoHSS9uKYc6vdZi1NW-GUJw130_assertion description "[We examined the antitumor effects of targeting SF/HGF and c-met expression in pre-established glioma xenografts by using novel chimeric U1snRNA/ribozymes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395760.RAe78H-UPFMHZspbGIwXd3aoHSS9uKYc6vdZi1NW-GUJw130_provenance.
NP395762.RAaoIzQsbWcntxy5CBrESeMPdJvV1LX6wWf39C6YCXRlk130_assertion description "[The hypervariable regions of 26 clones of six patients with chronic hepatitis C were expressed as proteins fused with glutathione S-transferase, and sera of the patients were serially tested for antibody to these proteins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395762.RAaoIzQsbWcntxy5CBrESeMPdJvV1LX6wWf39C6YCXRlk130_provenance.
NP395763.RAR68tuw94BhgF2sZnyE6NRYPaI_758L7UC2tvRED5kF0130_assertion description "[This case represents the first association of a somatic HIF2A gain-of-function mutation with PHEO and congenital polycythemia, and it alerts physicians to perform proper genetic screening in patients presenting with multiple norepinephrine-producing PHEOs and polycythemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395763.RAR68tuw94BhgF2sZnyE6NRYPaI_758L7UC2tvRED5kF0130_provenance.
NP395765.RAUazEwwXj1FDQ7gPaY7qAbXujxVKrw6Ki2XdJUA0GAtg130_assertion description "[Common polymorphisms involved in the tryptophan hydroxylase 1 (TPH1) and 2 (TPH2), serotonin transporter, monoamine oxidase A (MAOA) and brain-derived neurotrophic factor (BDNF) were investigated in a naturalistic inpatient study of the German research network on depression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395765.RAUazEwwXj1FDQ7gPaY7qAbXujxVKrw6Ki2XdJUA0GAtg130_provenance.
NP395772.RAcZ8M26BxjV_1uVfJNaCTEnIGNORo-PFjM3_wO3ofNKs130_assertion description "[However, when the wild-type MPO allele was considered together with the CYP2E1 and NQO1 risk-elevating genotypes, the risk of ALL was increased further (OR = 5.4, 95%CI, 1.2-23.4) suggesting a combined effect.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395772.RAcZ8M26BxjV_1uVfJNaCTEnIGNORo-PFjM3_wO3ofNKs130_provenance.
NP395773.RAXj63QTumQhr-ZIcV-nk-GrD3AymgJSBosWG-3dsWtNc130_assertion description "[The evidence that mechanisms other than P-170 expression may influence its `pump` and the retention/efflux of chemotherapeutic agents, prompted us to investigate the value of a functional multidrug resistance (MDR) assay in a series of childhood acute leukemia samples.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395773.RAXj63QTumQhr-ZIcV-nk-GrD3AymgJSBosWG-3dsWtNc130_provenance.
NP395783.RAcqCZok-ZKBoXlCGjV9_SIuh3hMZPbJuh4-ELNuCGjHo130_assertion description "[Our finding adds to the evidence for monoclonality in parathyroid adenomatosis, indicates that only one PTH gene copy is sufficient for hyperparathyroid tumor function, and raises the possibility that a tumor-suppressor gene important in the development of nonfamilial parathyroid neoplasia is located on chromosome 11.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395783.RAcqCZok-ZKBoXlCGjV9_SIuh3hMZPbJuh4-ELNuCGjHo130_provenance.
NP395787.RAX4xfkELn_EYZPlWVAMQb2NlVD6SiIe1x-xdltGKtdwk130_assertion description "[Association of EBF1, FAM167A(C8orf13)-BLK and TNFSF4 gene variants with primary Sjögren's syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395787.RAX4xfkELn_EYZPlWVAMQb2NlVD6SiIe1x-xdltGKtdwk130_provenance.
NP395791.RAeWIJV1IXzfwLwBRllb09WfRdx4L4YCCjj1ZTjKHCXUw130_assertion description "[In a case-control sample that has shown the well established associations between AMD and variants in CFH, CFB and C3 there was absence of association with SNPs in CFP, CD46, CD55 and CD59.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395791.RAeWIJV1IXzfwLwBRllb09WfRdx4L4YCCjj1ZTjKHCXUw130_provenance.
NP395800.RAXmeB1etNP_9Wca3QfuX3yNDMoMB4prJdqw0jtV_o9Tk130_assertion description "[Thus, targeting the Ras-Raf-ERK pathway for HO-1 overexpression may serve as novel therapeutics for the treatment of renal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395800.RAXmeB1etNP_9Wca3QfuX3yNDMoMB4prJdqw0jtV_o9Tk130_provenance.
NP395803.RAZ3iwhs21eWkZfztduK5vleU6BfdhzZmcN8auK7msrlk130_assertion description "[Patients with thymoma were typically homozygous for both the TNFA*T1 and the TNFB*2 alleles, but patients having an early onset of MG without thymoma were carriers of the TNFA*T2 and TNFB*1 alleles.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395803.RAZ3iwhs21eWkZfztduK5vleU6BfdhzZmcN8auK7msrlk130_provenance.
NP395804.RAZW9NSIqjFPZ6-pRSCsVUhTb8OzUBcOCzjIX1gXVj1Hg130_assertion description "[The A-allele of rs2070106 within the 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), an oligodendrocyte-related gene, was reported to show reduced expression compared with the G-allele, and proposed to be associated with schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395804.RAZW9NSIqjFPZ6-pRSCsVUhTb8OzUBcOCzjIX1gXVj1Hg130_provenance.
NP395808.RAV8XcY5GAcHjdcMDfVeki17HBjv1VUDKoNK-qL-Bbyz8130_assertion description "[Gastrin-induced release of calcitonin from medullary thyroid carcinomas (MTC) is based on the expression of the cholecystokinin(2)-receptor (CCK(2)R) in these tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395808.RAV8XcY5GAcHjdcMDfVeki17HBjv1VUDKoNK-qL-Bbyz8130_provenance.
NP395809.RAcFSBcNgp263OBZAoQ8QtKef9jDtX6-DJoOgJ9LZ-2t4130_assertion description "[Following the discovery of two disorders associated with premutation alleles of the fragile X mental retardation gene (FMR1), primary ovarian insufficiency [fragile X-associated primary ovarian insufficiency (FXPOI)] and a tremor/ataxia syndrome [fragile X-associated tremor/ataxia disorder (FXTAS)], numerous studies have examined other potential co-morbid conditions, including neuropsychological deficits.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395809.RAcFSBcNgp263OBZAoQ8QtKef9jDtX6-DJoOgJ9LZ-2t4130_provenance.
NP395811.RAWI3YqX8FLQsSqa9N21dn7lV2x-7Mbhzn5L0Uuw-JfKE130_assertion description "[Significantly higher frequencies of the G allele and CG/GG genotype of the 213 SOD3 polymorphism were found in resistant smokers (odds ratios (ORs) 4.3 (95% CI 1.5 to 13.3) and 4.2, 95% CI 1.4 to 13.3), Bonferroni corrected p = 0.02 and p = 0.02, respectively) than in those with COPD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395811.RAWI3YqX8FLQsSqa9N21dn7lV2x-7Mbhzn5L0Uuw-JfKE130_provenance.
NP395825.RAR1Nmi50J0ppqy4IHiGUA6I84XGQCtuEPb5R3R_lF6kM130_assertion description "[We assessed atherosclerosis in LZ-Tg mice crossed with ApoE((-/-)) mice (LZ/ApoE((-/-))) and found increased serum LZ levels and decreased AGE and 8-isoprostanes levels, although hyperlipidemia remained similar to ApoE((-/-)) controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395825.RAR1Nmi50J0ppqy4IHiGUA6I84XGQCtuEPb5R3R_lF6kM130_provenance.
NP395830.RAQ4sWQyd08c0Y4Jc2CoYB0hDxBRBx6PWaphFIREqAROI130_assertion description "[Apart from neurological impairment, the disease is also accompanied by progressive weight loss, abnormalities in glucose homeostasis and a higher prevalence of diabetes mellitus, which may partly be caused by disturbed growth hormone (GH) and ghrelin secretion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395830.RAQ4sWQyd08c0Y4Jc2CoYB0hDxBRBx6PWaphFIREqAROI130_provenance.
NP395831.RAd6pUsXsTeZ4PIfAH5g0SIxhf4JBMvzmbe5Vd4FIvrBk130_assertion description "[The mitochondrial ribosomal protein S30 gene (MRPS30) rs10941679 was associated with breast cancer risk only among women with more than 30 years of menstruation (odds ratio = 1.15, 95% confidence interval: 1.05, 1.26).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395831.RAd6pUsXsTeZ4PIfAH5g0SIxhf4JBMvzmbe5Vd4FIvrBk130_provenance.
NP395839.RASVSLVkYUiv1sOUZi_MUpZ5r_2_B0Ng8wtSnFX8ggoaM130_assertion description "[A large-scale screening of mtDNA molecules from skeletal muscle was performed in 14 patients with progressive external ophthalmoplegia (PEO) and 2 patients with mitochondrial neurogastrointestinal encephalomyopathy carrying mutations on ANT1, C10ORF2 or POLG1, and TP genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395839.RASVSLVkYUiv1sOUZi_MUpZ5r_2_B0Ng8wtSnFX8ggoaM130_provenance.
NP395845.RAYw394JbBNpeOh6-EnCBqmi9xSuJ-oaIcx9mw3itJjeI130_assertion description "[Audioprofiling identifies TECTA and GJB2-related deafness segregating in a single extended pedigree.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395845.RAYw394JbBNpeOh6-EnCBqmi9xSuJ-oaIcx9mw3itJjeI130_provenance.
NP395847.RAWo94M7UO1RJ5kOhgKcwMA-14I1OroGpNtQ70ID7N_ns130_assertion description "[A gene-based analysis adjusting for the number of tag SNPs genotyped in each gene showed significant associations with risk of NHL combined and one or more NHL subtypes for Th1 (IL12A and IL12RB1) and Th2 (IL4, IL10RB, and IL18) genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395847.RAWo94M7UO1RJ5kOhgKcwMA-14I1OroGpNtQ70ID7N_ns130_provenance.
NP395849.RAQRjFIaHJKE4zHtc2aYf4CUiBNbnqjunidnIq8-ugh7Y130_assertion description "[Methylation-specific PCR (MSP) of cervical smears showed aberrant methylation of CHFR in 12.3% (2/14) of adenocarcinoma specimens.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395849.RAQRjFIaHJKE4zHtc2aYf4CUiBNbnqjunidnIq8-ugh7Y130_provenance.
NP395850.RAQj-_FzfxN5IoUUnAIH1OfaAoJ5VRNzsi9_CVXJV0uPM130_assertion description "[We found no consistent evidence of aberrant splicing or point mutations in breast cancer or Wilms' tumor suggesting that TSG101 is not a primary target of inactivation in human cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395850.RAQj-_FzfxN5IoUUnAIH1OfaAoJ5VRNzsi9_CVXJV0uPM130_provenance.
NP395858.RAajq2fMMwOa8JL3hICq2UwKqmukwhQsfjDJCldxrlGtI130_assertion description "[One third of Trypanosoma cruzi-infected individuals develop chronic Chagas disease cardiomyopathy (CCC) while the majority remains asymptomatic (ASY).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395858.RAajq2fMMwOa8JL3hICq2UwKqmukwhQsfjDJCldxrlGtI130_provenance.
NP395861.RASapDwZ75Ke_wgMJFCrKS-q6STtp45zYDq2yrPnF5vZU130_assertion description "[Our results suggest that PUMA induction through p73 represents a new mechanism of EGFR inhibitor-induced apoptosis, and provide potential ways for enhancing and predicting the sensitivity to EGFR-targeted therapies in HNSCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395861.RASapDwZ75Ke_wgMJFCrKS-q6STtp45zYDq2yrPnF5vZU130_provenance.
NP395862.RAap0lwVerSQ6tKYtTje0z-H7nEihVmEkejqSwrbD_WBo130_assertion description "[TP53 mutations in early-stage ovarian carcinoma, relation to long-term survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395862.RAap0lwVerSQ6tKYtTje0z-H7nEihVmEkejqSwrbD_WBo130_provenance.
NP395863.RAXMVPiVDDPf8gGLaazquxPLvbNFncT1bFhxbRb-JLcAc130_assertion description "[Upregulation of epidermal growth factor receptor (EGFR) and subsequent increases in extracellular-regulated kinase (ERK) and Akt signaling are implicated in prostate cancer progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395863.RAXMVPiVDDPf8gGLaazquxPLvbNFncT1bFhxbRb-JLcAc130_provenance.
NP395866.RAe_WZpdeJStH53eG5PN5BOErzecEfA3WrQwgfbuwn-fQ130_assertion description "[Consistent with the upregulated TGF-beta pathway in RA SFBs, stimulation with TGF-beta1 resulted in a significantly enhanced expression of matrix-metalloproteinase (MMP)-11 mRNA and protein in RA SFBs, but not in OA SFBs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395866.RAe_WZpdeJStH53eG5PN5BOErzecEfA3WrQwgfbuwn-fQ130_provenance.
NP395868.RAalm2xUtHNz8D5xoxoqK8vjWVed4uy_L3v8pZrZkgspY130_assertion description "[Our findings demonstrated that CAC1 promoted the proliferation of human lung cancer A549 cells with activation of ERK1/2 signaling pathways, suggesting a potential cure target for treatment of human lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395868.RAalm2xUtHNz8D5xoxoqK8vjWVed4uy_L3v8pZrZkgspY130_provenance.
NP395869.RAdw5cNAUZadrlKW3Nmgdw5-m6IkYbPEzQEHJrPaMKDgg130_assertion description "[The miRNA-17∼92 cluster mediates chemoresistance and enhances tumor growth in mantle cell lymphoma via PI3K/AKT pathway activation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395869.RAdw5cNAUZadrlKW3Nmgdw5-m6IkYbPEzQEHJrPaMKDgg130_provenance.
NP395870.RAezO5csK4WyEHv3aO1cSCiRsnNqxSd28xPpQccRGiCAQ130_assertion description "[Ad-SCL was able to enhance c-Kit expression, reactivate the c-Kit/SCF pathway, and rescue ICC in ICC-loss mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395870.RAezO5csK4WyEHv3aO1cSCiRsnNqxSd28xPpQccRGiCAQ130_provenance.
NP395872.RAR19Qa5vNQddOgbLRlfWPQu7cFOPCTlQ50hi_8ZESAcA130_assertion description "[In ovarian carcinoma, acquisition of invasiveness is accompanied by the loss of the epithelial features and the gain of a mesenchymal phenotype, a process known as epithelial-mesenchymal transition (EMT).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395872.RAR19Qa5vNQddOgbLRlfWPQu7cFOPCTlQ50hi_8ZESAcA130_provenance.
NP395885.RAXHW1aTT4p4FQofVlQe29QJy_YSj4fepYqmTBFy4Xsco130_assertion description "[A murine in vivo xenograft model of the most common paxillin mutation (A127T) showed increased cell proliferation and invasive tumour growth, establishing an important role for paxillin in the development of lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP395885.RAXHW1aTT4p4FQofVlQe29QJy_YSj4fepYqmTBFy4Xsco130_provenance.

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