Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Sleep+apnea+syndrome+is+associated+with+plasma+soluble+leptin+receptor+and+insulin+resistance+independently+of+body+mass+index. assertion.
- assertion asSentence Human+natural+killer+cell+lines+express+leptin+receptors. assertion.
- assertion asSentence Effect+pf+genetic+and+environmental+factors+on+levels+in+female+twins+in+puberty. assertion.
- assertion asSentence Allelic+variants+are+specifically+associated+with+distinctly+different+eating+patterns%2C+namely+extreme+snacking+behavior+or+excessive+portion+size. assertion.
- assertion asSentence Polymorphism+of+human+leptin+receptor+gene+is+associated+with+type+2+diabetic+patients+complicated+with+non-alcoholic+fatty+liver+disease+in+China. assertion.
- assertion asSentence LEPR+Q223R+polymorphism+is+one+of+the+factors+contributing+to+the+high+prevalence+of+obesity+in+the+Pacific+Island+populations. assertion.
- assertion asSentence Leptin+receptor+ventral+tegmental+area+%28VTA%29neurons+represent+a+subclass+of+VTA+dopaminergic+neurons+that+innervates+and+controls+the+extended+central+amygdala. assertion.
- assertion asSentence Both+endospanins+are+regulators+of+postinternalization+membrane+traffic+of+the+endocytic+pathway+of+OB-R. assertion.
- assertion asSentence LETM1+is+evolutionarily+conserved+throughout+the+eukaryotic+kingdom+and+located+in+the+mitochondria. assertion.
- assertion asSentence Galectin-1+decreases+Smad3-complex+from+binding+to+the+SBE%2C+down-regulating+transcription+of+COL1A2+in+TGF-beta1-stimulated+renal+epithelial+cells. assertion.
- assertion asSentence Galectin-3+expressed+in+human+monocytes+is+a+receptor+for+the+major+xenoantigen+Gal-alpha%281%2C3%29Gal-beta%281%2C4%29GlcNAc-R%2C+expressed+on+porcine+endothelial+cells. assertion.
- assertion asSentence Mutational+tuning+of+galectin-3+specificity+and+biological+function. assertion.
- assertion asSentence High+Galectin-3+is+associated+with+undifferentiated+nasopharyngeal+carcinoma. assertion.
- assertion asSentence Galectin-3+contributes+to+the+plasma+membrane+retention+and+proangiogenic+function+of+VEGF-R2. assertion.
- assertion asSentence Serum+concentrations+of+high+galectin-3+is+not+associated+with+pancreatic+ductal+adenocarcinoma. assertion.
- assertion asSentence Changes+in+the+cellular+level+of+galectin-3+correlate+with+the+development+of+clear+cell+renal+cell+carcinoma. assertion.
- assertion asSentence Galectin-3+is+overexpressed+in+hepatocellular+carcinoma+tissues+and+is+correlated+with+the+tumor+differentiation. assertion.
- assertion asSentence DC-expressed+Gal-1+and+Gal-3+are+regulatory+molecules+that+favor+the+inhibition+of+T+cell+activation. assertion.
- assertion asSentence High+galectin-3+is+associated+with+mesothelioma+in+pleural+effusions. assertion.
- assertion asSentence The+combination+of+Galectin-3+and+PTTG+is+complementary+as+a+diagnostic+biomarker+for+patients+with+papillary+carcinoma. assertion.
- assertion asSentence GAL7+is+a+negative+growth+regulator+for+human+neuroblastoma+cells. assertion.
- assertion asSentence Galectin-7+modulates+the+length+of+the+primary+cilia+and+wound+repair+in+polarized+kidney+epithelial+cells. assertion.
- assertion asSentence Inactivating+mutations+of+luteinizing+hormone+beta-subunit+or+luteinizing+hormone+receptor+cause+oligo-amenorrhea+and+infertility+in+women. assertion.
- assertion asSentence Variant+LH+remains+longer+in+circulation+than+wild+type+during+GnRH+receptor+blockade+in+heterozygous+women%2C+in+accord+with+its+higher+content+of+sialic+acid. assertion.
- assertion asSentence Ectodomain+has+major+function+apart+from+hormone+binding%2C+also+interacts+with+transmembrane+domain. assertion.
- assertion asSentence LIF+plays+an+essential+role+in+the+preimplantation+embryo+development+and+the+blastocyst+implantation+and+its+gene+mutations+in+women+contribute+to+the+implantation+failure+and+subsequent+infertility. assertion.
- assertion asSentence Ciliary+neurotrophic+factor%2FLIF+signaling+pathway+acts+via+regulation+of+nitric+oxide+production+to+modulate+developmental+programmed+cell+death+of+postmitotic+rod+precursor+cells. assertion.
- assertion asSentence The+antiphospolipid+antibodies+%28aPLs%29+are+elevated+in+infertile+women+with+LIF+gene+mutations. assertion.
- assertion asSentence Extensive+mannose+phosphorylation+on+leukemia+inhibitory+factor+%28LIF%29+controls+its+extracellular+levels+by+multiple+mechanisms. assertion.
- assertion asSentence LIF+delivery+can+be+harnessed+to+enhance+the+generation+of+oligodendrocytes+that+express+myelin+proteins+and+reform+the+nodes+of+Ranvier+in+the+context+of+chronic+demyelination+in+the+adult+mouse+hippocampus. assertion.
- assertion asSentence Expression+of+LIF+and+integrin-beta3+%28ITGB3%29+in+the+peri-implantation+endometrium+does+not+change+in+women+with+unexplained+recurrent+pregnancy+loss. assertion.
- assertion asSentence DNA+ligase+I+competes+with+FEN1+to+expand+repetitive+DNA+sequences+in+vitro. assertion.
- assertion asSentence DNA+Ligase+IV%2FXRCC4+recruitment+by+DNA-PK+to+DNA+double-strand+breaks+prevents+the+formation+of+long+ssDNA+ends+at+double-strand+breaks+during+the+S+phase. assertion.
- assertion asSentence Omenn+syndrome+is+associated+with+mutations+in+DNA+ligase+IV. assertion.
- assertion asSentence LIM+kinase+1+%28LIMK1%29%2C+a+critical+regulator+of+actin+dynamics%2C+plays+a+regulatory+role+in+tumor+cell+invasion. assertion.
- assertion asSentence High+LIMK1+is+associated+with+cervical+cancer+dysplasia. assertion.
- assertion asSentence PINCH+protein+is+overexpressed+in+tumor-associated+stroma+of+esophageal+squamous+cell+carcinoma. assertion.
- assertion asSentence Hepatic+lipase+C514T+polymorphism+and+its+relationship+with+coronary+artery+disease+in+Koreans. assertion.
- assertion asSentence The+-250G%2FA+polymorphism+in+the+HL+gene+is+associated+with+significant+variations+in+high-density+lipoprotein+C+levels+and+coronary+artery+disease+risk+in+males. assertion.
- assertion asSentence -514C--%3ET+gene+polymorphism+correlates+with+elevated+fasting+insulin+concentrations+in+a+German+population. assertion.
- assertion asSentence Plasma+HDL-Cholesterol+varied+according+to+hepatic+lipase+%28LIPC%29+genotypes+and+with+dietary+intake+of+fats. assertion.
- assertion asSentence Hence%2C+rs6084+is+not+consistently+associated+with+LOAD. assertion.
- assertion asSentence LIPC+is+associated+with+reduced+risk+of+advanced+age-related+macular+degeneration. assertion.
- assertion asSentence Adipose+triglyceride+lipase+and+hormone+sensitive+lipase+are+responsible+for+more+than+95%25+of+the+triacylglycerol+hydrolase+activity+present+in+murine+white+adipose+tissue. assertion.
- assertion asSentence M.+leprae+suppresses+lipid+degradation+through+inhibition+of+HSL+expression. assertion.
- assertion asSentence Genetic+variants+of+the+fatty+acid+desaturase+gene+cluster+predict+amounts+of+red+blood+cell+docosahexaenoic+and+other+polyunsaturated+fatty+acids+in+pregnant+women. assertion.
- assertion asSentence There+is+a+role+of+Lgl2+immunohistochemistry+as+an+adjunct+in+the+diagnosis+of+foveolar-type+gastric+dysplasia. assertion.
- assertion asSentence UBXD1+modulates+the+trafficking+of+ERGIC-53-containing+vesicles+by+controlling+the+interaction+of+transport+factors+with+the+cytoplasmic+tail+of+ERGIC-53. assertion.
- assertion asSentence Lamin+A-binding+is+mediated+by+the+central+region+of+emerin%2C+residues+70-178%2C+outside+the+LEM-domain. assertion.
- assertion asSentence LMNA+missense+mutations+in+nondiabetic+carriers+with+Dunnigan-type+familial+partial+lipodystrophy+%28FPLD%29+are+associated+with+elevated+levels+of+serum+C-reactive+protein+and+free+fatty+acid%2C+particularly+in+women. assertion.
- assertion asSentence Mutations+in+LMNA+cause+a+severe+and+progressive+dilated+cardiomyopathy+in+a+relevant+proportion+of+patients. assertion.
- assertion asSentence Two+patients+with+%27Dropped+head+syndrome%27+due+to+mutations+in+LMNA+genes. assertion.
- assertion asSentence Two+homozygous+missense+LMNA+mutations+involving+the+arginine+527+and+alanine+529+residues+cause+MAD+with+subtle+variations+in+phenotype. assertion.
- assertion asSentence The+mutant+lamin+A+%28progerin%29+accumulates+in+the+nucleus+in+a+cellular+age-dependent+manner. assertion.
- assertion asSentence The+major+causal+mutation+associated+with+HGPS+triggers+abnormal+messenger+RNA+splicing+of+the+lamin+A+gene+leading+to+changes+in+the+nuclear+architecture. assertion.
- assertion asSentence Unusual+LMNA+mutations+associated+with+severe+progeria. assertion.
- assertion asSentence Malignant+mutation+in+lamin+A%2FC+gene+causing+progressive+conduction+system+disease+and+early+death+in+limb-girdle+muscular+dystrophy. assertion.
- assertion asSentence Lamin+A-type+lamins+affect+both+nuclear+membrane+and+telomere+dynamics%2C+as+demonstrated+in+nonsense+mutations+in+progeria. assertion.
- assertion asSentence The+role+of+LMNA+mutations+at+position+R541+in+dilated+familial+cardiomyopathy+cases+with+segmental+LV+wall+motion+akinesis%2Fdyskinesis. assertion.
- assertion asSentence The+article+presents+clinical+description+of+nucleopathies+in+children%2C+their+causative+mutations+and+pathophysiology. assertion.
- assertion asSentence LMNA+1908T%2FT+and+C%2FT+genotypes+emerged+as+independent+genetic+risk+factors+for+generalized+obesity+in+Asian+north+Indians. assertion.
- assertion asSentence The+loss+of+nuclear+envelope+structural+proteins+lamin+A%2FC+in+breast+cancer+underlies+the+two+hallmarks+of+cancer+aberrations+in+nuclear+morphology+and+aneuploidy. assertion.
- assertion asSentence Three+of+87+patients+with+metabolic+syndrome+carry+a+heterozygous+mutation+in+LMNA+or+in+ZMPSTE24. assertion.
- assertion asSentence Autosomal+dominant+leukodystrophy+is+the+first+disease+that+has+ever+been+linked+to+lamin+B1+mutations+and+it+expands+the+pathological+role+of+the+nuclear+lamia+to+include+disorders+of+the+brain. assertion.
- assertion asSentence A+self-sustaining+triad+of+LMO2%2FERG%2FFLI1+stabilizes+the+expression+of+important+mediators+of+the+leukaemic+phenotype+such+as+HHEX%2FPRH. assertion.
- assertion asSentence Functional+interaction+between+emerin+and+Lmo7+is+crucial+for+temporally+regulating+the+expression+of+key+myogenic+differentiation+genes. assertion.
- assertion asSentence The+Lmx1a+can+induce+desired+neuronal+lineages+from+most+expressing+neural+progenitor+cells+by+a+mechanism+resembling+developmental+binary+cell-fate+switching. assertion.
- assertion asSentence Podocin+is+specifically+regulated+by+the+transcription+factor+Lmx1b+and+by+the+functional+polymorphism+-116C%2FT. assertion.
- assertion asSentence LOX+regulates+control+of+normal+collagen+deposition+in+differentiating+osteoblast+cultures. assertion.
- assertion asSentence High+Lysyl+oxidase+is+associated+with+lymph+node+metastasis+in+esophageal+squamous+cell+carcinoma. assertion.
- assertion asSentence The+LOXL1+SNPs+R141L+and+G153D+are+significantly+associated+with+exfoliation+syndrome+in+this+black+South+African+population. assertion.
- assertion asSentence LOXL1+is+a+susceptibility+gene+of+exfoliation+syndrome%2Fexfoliation+glaucoma+%28XFS%2FXFG%29+in+Uygur+populations+of+China. assertion.
- assertion asSentence The+human+lysyl+oxidase-like+1+gene+does+not+confer+increased+genotypic+risk+for+adolescent+idiopathic+scoliosis. assertion.
- assertion asSentence Three+LOXL1+single+nucleotide+polymorphisms+are+associated+with+exfoliation+syndrome+in+the+Korean+population. assertion.
- assertion asSentence The+R141L+and+G153D+variations+in+the+NH2-terminal+region+of+LOXL1+do+not+affect+the+amine+oxidase+activity+of+LOXL1+associated+with+exfoliation+glaucoma. assertion.
- assertion asSentence Blood+levels+are+higher+in+coronary+artery+disease+patients+compared+with+normal+values. assertion.
- assertion asSentence Major+5-polymorphic+compound+genotypes+are+not+associated+with+restricted+range+of+Lp%28a%29+levels. assertion.
- assertion asSentence Aspirin+lowers+the+increased+Lp%28a%29+levels+in+patients+with+ischemic+stroke. assertion.
- assertion asSentence Elevated+lipoprotein+Lp%28a%29+levels+confer+genetic+predisposition+to+coronary+artery+disease+in+young+Asian+Indians. assertion.
- assertion asSentence There+is+a+causal+association+between+elevated+lipoprotein%28a%29+levels+and+increased+risk+of+myocardial+infarction. assertion.
- assertion asSentence LPL+is+bound+to+postprandial+triglyceride-rich+lipoproteins+and+mediates+their+hepatic+clearance+in+vivo. assertion.
- assertion asSentence High+concentration+of+triglyceride+and%2For+low+concentration+of+HDL-cholesterol+are+associated+with+high+blood+pressure+in+hypertensive+patients+with+the+X447+allele+of+the+LPL+gene. assertion.
- assertion asSentence Beta-cell+LPL+has+two+physiologically+relevant+effects+in+islets%2C+the+inverse+regulation+of+glucose+metabolism+and+the+independent+mediation+of+insulin+secretion+through+effects+distal+to+membrane+depolarization. assertion.
- assertion asSentence The+polymorphisms+of+intron+8+in+lipoprotein+lipase+influence+the+blood-lipid+metabolism%2C+induce+blood+vessel+rebuilding+and+play+an+important+role+in+the+invasion+and+development+of+Essential+Hypertension. assertion.
- assertion asSentence Serum+levels+are+lower+in+type+2+diabetes+than+in+normal+persons. assertion.
- assertion asSentence Changes+in+DNA+methylation+at+adipogenic+promoters+during+cellular+aging. assertion.
- assertion asSentence The+12-amino+acid+consensus+motif+within+the+CCD+of+Angptl4%2C+especially+the+three+polar+residues+within+this+motif%2C+is+responsible+for+its+interaction+with+and+inhibition+of+LPL+by+blocking+the+enzyme+dimerization. assertion.
- assertion asSentence The+cleavage+of+ANGPTL4+by+these+PCs+modulates+its+inhibitory+effect+on+LPL+activity. assertion.
- assertion asSentence LPP+is+a+nucleocytoplasmatic+shuttle+protein+linking+focal+adhesion+dynamics+to+the+transcriptional+machinery. assertion.
- assertion asSentence Low-density+lipoprotein+receptor-related+protein+LRP+interaction+with+amyloid+beta-peptide+%28Abeta%29+and%2For+Abeta-induced+LRP+loss+at+the+blood-brain+barrier+mediate+brain+accumulation+of+neurotoxic+Abeta. assertion.
- assertion asSentence LRP-mediated+clearance+of+uPA+is+one+of+the+mechanisms+involved+during+the+control+of+human+thyroid+carcinoma+cell+invasion. assertion.
- assertion asSentence Low-density+lipoprotein+receptor-related+protein+1+is+an+essential+receptor+for+myelin+phagocytosis. assertion.
- assertion asSentence Hypoxia+upregulates+LRP1+expression+and+aggregated+low-density+lipoprotein-derived+intracellular+cholesterol+esters+accumulation+in+human+vascular+smooth+muscle+cells+through+HIF-1alpha+induction. assertion.
- assertion asSentence Polymorphisms+within+the+megalin+gene+for+associations+with+prostate+cancer+risk+and+outcomes. assertion.
- assertion asSentence Expression+of+the+Wnt+signaling+coreceptor+LRP6+is+up-regulated+in+a+subpopulation+of+human+breast+cancers. assertion.
- assertion asSentence Two+structural+and+functional+domains+of+MESD+required+for+proper+folding+and+trafficking+of+LRP5%2FLRP6. assertion.
- assertion asSentence Two+gene+variants+of+key+biological+proteins+increase+the+risk+of+osteoporosis+and+osteoporotic+fracture. assertion.
- assertion asSentence Two+structural+and+functional+domains+of+MESD+required+for+proper+folding+and+trafficking+of+LRP5%2FLRP6. assertion.
- assertion asSentence Suppression+of+2%2C3-oxidosqualene+cyclase+by+high+fat+diet+contributes+to+liver+X+receptor-alpha-mediated+improvement+of+hepatic+lipid+profile. assertion.
- assertion asSentence Role+of+specific+LTA+genetic+polymorphisms+on+lethal+infections+during+induction+chemotherapy+of+ALL+treatment. assertion.