Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP486943.RAZryP5B8ywpM9kRDMdeJA1rdiX6V1DzSo3CZ2Kg7fxJE130_assertion description "[The human gene HIRA lies within the smallest critical region for the DiGeorge syndrome (DGS), a haploinsufficiency developmental disorder associated with instertitial deletions in most patients in a juxtacentromeric region of chromosome 22.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP486943.RAZryP5B8ywpM9kRDMdeJA1rdiX6V1DzSo3CZ2Kg7fxJE130_provenance.
- NP486944.RAdxwmL4oAxY2aL221A_fzgwS0QCW1JzTfP8f1aVvboiA130_assertion description "[These data suggested that exogenous IL-10 may be useful in the treatment of pulmonary fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP486944.RAdxwmL4oAxY2aL221A_fzgwS0QCW1JzTfP8f1aVvboiA130_provenance.
- NP486950.RATOlOKiIp8M8huVQUoBw4SgxTyBZH-NPyLIpA1U_ImkU130_assertion description "[Immunoblotting detects up to seven different cross-reacting SHIP species, with peripheral blood mononuclear cells exhibiting primarily a 100-kD protein and a CD34+ acute myeloblastic leukemia expressing mainly 130-kD and 145-kD forms of SHIP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP486950.RATOlOKiIp8M8huVQUoBw4SgxTyBZH-NPyLIpA1U_ImkU130_provenance.
- NP486951.RASPc_zBUDV0f-xqRnANp_H6r1T4KnR0qbja9i0k3E1n4130_assertion description "[In vitro, the luciferase assay further showed an increased transcriptional activity of SNP309G allele compared with SNP309T allele, and the function of polymorphism T309G in MDM2 gene promoter was intensified by H. pylori LPS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP486951.RASPc_zBUDV0f-xqRnANp_H6r1T4KnR0qbja9i0k3E1n4130_provenance.
- NP486958.RAbp0N_H_A8JZmAJ8m8LHhIh4Qg6Y8KbxqI-7ZY4NlSLI130_assertion description "[Consistent with the absence of muscular symptoms in these patients, muscle biopsies from several epidermolysis bullosa simplex Ogna members of the Norwegian kindred showed normal staining patterns using antibodies to plectin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP486958.RAbp0N_H_A8JZmAJ8m8LHhIh4Qg6Y8KbxqI-7ZY4NlSLI130_provenance.
- NP486963.RAWJEwMr65qcCRoci_8s2JU2xKHLGZpI2Nql70XREhh44130_assertion description "[The activity of six P450 isoforms (CYP1A2, 2C9, 2C19, 2D6, 2E1, and 3A4) was evaluated in 31 patients with different pathologies, predominantly biliary atresia (n = 23).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP486963.RAWJEwMr65qcCRoci_8s2JU2xKHLGZpI2Nql70XREhh44130_provenance.
- NP486974.RAW-YazoO7H_E3EzNCR88OoQIIbg7Lj8vcSYj1whMcwJA130_assertion description "[Some of these gene products are specifically dedicated to B(12) transport, whereas others embrace additional roles, which explains the heterogeneity in the clinical picture of the many genetic disorders causing B(12) deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP486974.RAW-YazoO7H_E3EzNCR88OoQIIbg7Lj8vcSYj1whMcwJA130_provenance.
- NP486975.RAeKzbme1H2UyEUXPVHFKV6kSYCcwIvvpLrMC1-j3kj74130_assertion description "[Differential association of common carotid intima-media thickness and carotid atherosclerotic plaques with parental history of premature death from coronary heart disease : the EVA study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP486975.RAeKzbme1H2UyEUXPVHFKV6kSYCcwIvvpLrMC1-j3kj74130_provenance.
- NP486998.RAbqRXTTMVkFqAQwjhKu8nMEsrDDK7W97fuywVQN3CCjc130_assertion description "[One cardinal feature of Huntington's disease (HD) is the degeneration of striatal neurons, whose survival greatly depends on the binding of cortical brain-derived neurotrophic factor (BDNF) with high-affinity (TrkB) and low-affinity neurotrophin receptors [p75 pan-neurotrophin receptor (p75(NTR))].]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP486998.RAbqRXTTMVkFqAQwjhKu8nMEsrDDK7W97fuywVQN3CCjc130_provenance.
- NP487005.RAX6eaS7klkSe-D6zF1gT3uijt2zMXLJe3BKnWwNGmXO8130_assertion description "[Prenatal diagnosis of 3 HBB gene mutations causing β-thalassemia and hemoglobin D Punjab segregated in a South Indian nuclear family is reported along with a method identified as control for maternal cell contamination (MCC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487005.RAX6eaS7klkSe-D6zF1gT3uijt2zMXLJe3BKnWwNGmXO8130_provenance.
- NP487020.RAUMee36j_lZzJtMRemBXPecvlgV3RqDnDKSjusZ8q8Tc130_assertion description "[We conclude that both AIE-75 and villin appear to be brush border autoantigens in IPEX syndrome and could be used for the diagnosis of AIE in patients with presumptive IPEX syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487020.RAUMee36j_lZzJtMRemBXPecvlgV3RqDnDKSjusZ8q8Tc130_provenance.
- NP487030.RASEhb9VlAGX9bfT6fBBxYKEn8WdwOTpjWOHQnpt2OPv0130_assertion description "[NELL1 hypermethylation frequency was zero in NE but increased early during neoplastic progression, to 41.7% in BE from patients with Barrett's alone, 52.5% in D and 47.8% in EAC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487030.RASEhb9VlAGX9bfT6fBBxYKEn8WdwOTpjWOHQnpt2OPv0130_provenance.
- NP487032.RAchRzBzi0NTrKopVm_hZntyEYTB5Wed1IyZ4imIiOV84130_assertion description "[Compared with parental NU/Mock3, NU/Cap12, and NU/Cap32 cells: 1) induced higher tumor angiogenesis than NU/Mock3 cells accompanied by infiltration of tumor-associated macrophages in mouse dorsal air sac assay and Matrigel plug assay; 2) showed much higher expression of CXC chemokines, MMP-1, and the potent angiogenic factor VEGF-A; 3) increased the expression of the representative inflammatory cytokine, IL-1α; 4) augmented JNK phosphorylation and nuclear expression of activator protein 1 (AP-1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487032.RAchRzBzi0NTrKopVm_hZntyEYTB5Wed1IyZ4imIiOV84130_provenance.
- NP487036.RAW1PmHgFh7gxLJyTn8VGGbkIYGEZRI4NWDKRk9iIDD2U130_assertion description "[Thus, complete absence of ALDP expression results in a VLCFA storage disease but does not impair CNS function of young adult mice by pathologic and clinical criteria.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487036.RAW1PmHgFh7gxLJyTn8VGGbkIYGEZRI4NWDKRk9iIDD2U130_provenance.
- NP487039.RAdMDD2npakcYCRjmsise3kwytsWQ14x2hGNIN8ZM7vfY130_assertion description "[Expression of mutant catalytically inactive ADAM10 led to an enhancement of the number and size of amyloid plaques in the brains of double-transgenic mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487039.RAdMDD2npakcYCRjmsise3kwytsWQ14x2hGNIN8ZM7vfY130_provenance.
- NP487041.RAeqBu7VupUhksGO7sGwra-u7LmtzDuPXjjdl4xPprs4o130_assertion description "[Epstein-Barr virus DNA and EBV antibodies were not detected in the CSF of 17 EBV-seropositive patients with mumps meningitis, rubella encephalitis, unknown febrile convulsion, or partial epilepsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487041.RAeqBu7VupUhksGO7sGwra-u7LmtzDuPXjjdl4xPprs4o130_provenance.
- NP487042.RAVTjcudSZdI4odWvve2aJXnTB1ljEBGjVYsxtNCiShQY130_assertion description "[Therefore, in order to identify variant dopamine D2 receptors, we searched for mutations in the RNA transcripts for the dopamine D2 receptor in the striatum of post-mortem brains from individuals who died with psychosis, including schizophrenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487042.RAVTjcudSZdI4odWvve2aJXnTB1ljEBGjVYsxtNCiShQY130_provenance.
- NP487045.RAZPXYHEEUojqMYBvsNuV_YywKfmPeqlu79hwmcS0nW9k130_assertion description "[JAK2 V617F mutation was found to be positive in 100% of polycythemia vera cases, 68.29% of essential thrombocythemia cases, and 55.28% of all MPD cases whereas negative in idiopathic erythrocytosis, reactive thrombocytosis, and other non-MPD cases such as acute chronic myeloid leukemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487045.RAZPXYHEEUojqMYBvsNuV_YywKfmPeqlu79hwmcS0nW9k130_provenance.
- NP487051.RAVf3wIPCYHofDzBbicpbjBksAmW2cNtToxM-86DVD1rU130_assertion description "[Thus CAL appears to be an acceptable and effective method of teaching clinical medical students about familial breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487051.RAVf3wIPCYHofDzBbicpbjBksAmW2cNtToxM-86DVD1rU130_provenance.
- NP487057.RASEhs4YVPPEtEIR7KyHWibGgrvaPLtCctU6Exhq8glCc130_assertion description "[Junctional regions of rearranged TCR-gamma IgH genes in specimens of bone marrow aspirates of patients with ALL (precursor-B-ALL ten, T-ALL two, null-ALL one; ALL not classified one), of a patient with lymphoid blast crisis of chronic myeloid leukemia, of a B-cell chronic lymphocytic leukemia, and in DNA from peripheral blood mononuclear cells of ten healthy volunteers were amplified by polymerase chain reaction (PCR).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487057.RASEhs4YVPPEtEIR7KyHWibGgrvaPLtCctU6Exhq8glCc130_provenance.
- NP487060.RAfnr5ILd7GlMGdxx6eohXYecD6AjhAmdn5X1s-j0chww130_assertion description "[Analysis of trypsin-digested cN-CAM fragments by matrix-assisted laser desorption ionization on a time-of-flight mass spectrometer (MALDI-TOF) yielded peptides that could be identified as being derived from the first 548 amino acid residues of the expected N-CAM amino acid sequence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487060.RAfnr5ILd7GlMGdxx6eohXYecD6AjhAmdn5X1s-j0chww130_provenance.
- NP487065.RAUsErWsI5X1wZ11VpKU0K_FrJYxtGF7XRvSSNab2c-gc130_assertion description "[Immunoprecipitation and mass spectrometry analyses showed that antibodies from patients with limbic encephalitis previously attributed to voltage-gated potassium channels recognise LGI1, a neuronal secreted protein that interacts with presynaptic ADAM23 and postsynaptic ADAM22.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487065.RAUsErWsI5X1wZ11VpKU0K_FrJYxtGF7XRvSSNab2c-gc130_provenance.
- NP487072.RAZoi_snNoc_AwEV4DPnJBJ2dSo3DoJ7TXXmLKjvoskjA130_assertion description "[In contrast, the 2 polyps not associated with serrated crypts were negative for a BRAF mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487072.RAZoi_snNoc_AwEV4DPnJBJ2dSo3DoJ7TXXmLKjvoskjA130_provenance.
- NP487073.RAXFMD49NR-kfHyb4Ws0tM7O0XSTXEvUQFtCXYZ84BMdc130_assertion description "[We aimed to study the usefulness of trabectedin in the treatment of patients with myxoid liposarcomas, a subtype of liposarcoma that is associated with specific chromosomal translocations t(12;16)(q13;p11) or t(12;22)(q13;q12) that result in the formation of DDIT3-FUS or DDIT3-EWSR1 fusion proteins.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487073.RAXFMD49NR-kfHyb4Ws0tM7O0XSTXEvUQFtCXYZ84BMdc130_provenance.
- NP487074.RAQeIyyb4R6l_lujx3sFqhjW8ZneVFf8d6b4eysEckKGo130_assertion description "[SLA/LP/tRNP((Ser)Sec) antigen in autoimmune hepatitis: identification of the native protein in human hepatic cell extract.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487074.RAQeIyyb4R6l_lujx3sFqhjW8ZneVFf8d6b4eysEckKGo130_provenance.
- NP487081.RASyRhG1DpAIaLLdXRxu2-lqw1ipYm2jRHxfSV8JQOMgc130_assertion description "[Polymerase chain reaction, denaturing high-performance liquid chromatography, and DNA sequencing were used for a comprehensive mutational analysis of the 3 major LQTS-susceptibility genes (KCNQ1, KCNH2, and SCN5A), and a targeted analysis of the CPVT1-associated, RYR2-encoded cardiac ryanodine receptor was conducted.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487081.RASyRhG1DpAIaLLdXRxu2-lqw1ipYm2jRHxfSV8JQOMgc130_provenance.
- NP487083.RASCau9Sn-F1S2gASxU49g3osUNysNL_AOZpo17hfI1r8130_assertion description "[This study analysed 12 single-nucleotide polymorphisms (SNPs) in selenoprotein genes [glutathione peroxidase 1 (GPX1), GPX4, 15 kDa selenoprotein (SEP15), selenoprotein S (SELS), selenoprotein P (SEPP1) and thioredoxin reductase 2 (TXNRD2)] and in genes that code for a key protein in Se incorporation [SECIS-binding protein 2 (SBP2)] and in antioxidant defence [superoxide dismutase 2 (SOD2)] in relation to sporadic CRC incidence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487083.RASCau9Sn-F1S2gASxU49g3osUNysNL_AOZpo17hfI1r8130_provenance.
- NP487089.RAU4GZSXLPZOKfwAL2qMtaGcaJhrHCnD9JTYQ2VCNUE-Q130_assertion description "[The C-terminal tail of influenza virus NS1 protein constitutes a nucleolar localization signal (NoLS) and is the binding domain of the cellular pre-mRNA processing protein, poly(A)-binding protein II (PABII).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487089.RAU4GZSXLPZOKfwAL2qMtaGcaJhrHCnD9JTYQ2VCNUE-Q130_provenance.
- NP487093.RAU7Xg8J0eP-pHYFAwzmCsPMi8ErXUMM9qnheycybSwsQ130_assertion description "[Reduced expression of Popdc3 may play a significant role in the carcinogenesis and progression of gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487093.RAU7Xg8J0eP-pHYFAwzmCsPMi8ErXUMM9qnheycybSwsQ130_provenance.
- NP487094.RASy6m9enoW8s_MGPBxQLR4h3QMSOsz1Jsv-jzJqvc-x0130_assertion description "[These experiments of nature suggest that the TLR7-, TLR8-, and TLR9-dependent induction of IFN-alpha, IFN-beta, and IFN-lambda is largely redundant in human antiviral immunity, whereas the TLR3-dependent induction of IFN-alpha, IFN-beta, and IFN-lambda is critical for primary immunity to HSV-1 in the central nervous system in children but redundant for immunity to most other viral infections.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487094.RASy6m9enoW8s_MGPBxQLR4h3QMSOsz1Jsv-jzJqvc-x0130_provenance.
- NP487096.RAeykGbl1fUqj_HpVBYSGozkQvnD3uuk9Rju6TeFoXYvk130_assertion description "[Here we demonstrate the crucial role of CKS1B in multiple myeloma (MM) progression and define CKS1B-mediated SKP2/p27(Kip1)-independent down-stream signaling pathways.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487096.RAeykGbl1fUqj_HpVBYSGozkQvnD3uuk9Rju6TeFoXYvk130_provenance.
- NP487098.RAflmjBGC4z6x5neIZgPW-qM6dZj3J5nhx1_MImY00uSg130_assertion description "[Here, the known somatic mutational spectrum for the NF1 gene in a range of NF1-associated neoplasms - including peripheral nerve sheath tumours (neurofibromas), malignant peripheral nerve sheath tumours, gastrointestinal stromal tumours, gastric carcinoid, juvenile myelomonocytic leukaemia, glomus tumours, astrocytomas and phaeochromocytomas - have been collated and analysed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487098.RAflmjBGC4z6x5neIZgPW-qM6dZj3J5nhx1_MImY00uSg130_provenance.
- NP487103.RAY1uLRT0kcvETiDh5DFtaYem7jfsS3QZkDQiDz6YupNc130_assertion description "[Our results suggest that an area on chromosome 15 that includes DUOX1, DUOX2, and their maturation factors is a frequent target for epigenetic silencing in lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487103.RAY1uLRT0kcvETiDh5DFtaYem7jfsS3QZkDQiDz6YupNc130_provenance.
- NP487108.RAdOhc2x-ZKJ_K3l6_WwnX1xTXu7-uIxfLCvSfaT1IWMQ130_assertion description "[The predominance of genotype 2 in this study meant that we could not draw a conclusion for the role of GBV-C genotype in the reduced severity of liver disease in co-infected patients but CD4 positive T-cell counts appeared to be unaffected by GBV-C genotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487108.RAdOhc2x-ZKJ_K3l6_WwnX1xTXu7-uIxfLCvSfaT1IWMQ130_provenance.
- NP487112.RAcKGytb3ZY1hHxrF2jXR2bTKH-Exycn1JTfwHhfMouZc130_assertion description "[Here, we examined the Ig gene rearrangements of four patients with classical CVID and of one child suffering from an unusual immunodeficiency associated with CD5+ B cell lymphocytosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487112.RAcKGytb3ZY1hHxrF2jXR2bTKH-Exycn1JTfwHhfMouZc130_provenance.
- NP487116.RAUjPfXBpQS5QfyeVysG2pe8oEe-PpFBKWpxMUI4rPc58130_assertion description "[We found that expression of the ICSBP protein was significantly decreased in Bcr-Abl-induced CML-like disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487116.RAUjPfXBpQS5QfyeVysG2pe8oEe-PpFBKWpxMUI4rPc58130_provenance.
- NP487125.RAfHhQEBa85vRN_we5punpWOf4Pl7EoKdTb4s8AyNq_xA130_assertion description "[In multivariate Cox regression analyses, high NR4A2 expression in cancer nuclei (immunoreactive score ≥ 4) significantly predicted a shorter disease-specific survival (DSS) of CRC patients (hazard ratio [HR]=1.88, P=0.024).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487125.RAfHhQEBa85vRN_we5punpWOf4Pl7EoKdTb4s8AyNq_xA130_provenance.
- NP487126.RAYU3hlp_CiQ6jztgdEFchqaB34uf6O85SCCpGWIJekx4130_assertion description "[Together, our data indicate a positive cross talk between HBx and the MTA1/HDAC complex in stabilizing HIF-1 alpha, which may play a critical role in angiogenesis and metastasis of HBV-associated HCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487126.RAYU3hlp_CiQ6jztgdEFchqaB34uf6O85SCCpGWIJekx4130_provenance.
- NP487129.RAUn2yLAiRqOGTMYa5qgE0ToU5jjk7x4Smd8C77tCT6HU130_assertion description "[PAR1, alphavbeta5, and alpha-SMA colocalized to fibrotic foci in lung biopsy specimens from individuals with idiopathic pulmonary fibrosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487129.RAUn2yLAiRqOGTMYa5qgE0ToU5jjk7x4Smd8C77tCT6HU130_provenance.
- NP487131.RAVRIzkhQlz0CWyuIzy6vTYyTrRG55h1J9YkP3V9GzbDc130_assertion description "[High levels of plasma APOB and LDL cholesterol are strong predictors for risk of cardiovascular disease (CVD), while individuals with low APOB and LDL cholesterol levels are thought to have lower than average risk for CVD, and in fact, heterozygous FHBL patients appear to be asymptomatic.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487131.RAVRIzkhQlz0CWyuIzy6vTYyTrRG55h1J9YkP3V9GzbDc130_provenance.
- NP487133.RAf9UydOySW1vPx_ZYr1RsK_8pmbOroSV2mgISvsynnFk130_assertion description "[A novel 18-amino acid deletion in apolipoprotein E associated with lipoprotein glomerulopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487133.RAf9UydOySW1vPx_ZYr1RsK_8pmbOroSV2mgISvsynnFk130_provenance.
- NP487134.RATzrU1AMjAy07_qTYgjhqvsTZoDtjzXItHLKqzli9Ux0130_assertion description "[The DNA fragments including hot spots within the coding sequences of the MEFV gene were amplified by PCR using genomic DNA and analyzed by pyrosequencing technique.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487134.RATzrU1AMjAy07_qTYgjhqvsTZoDtjzXItHLKqzli9Ux0130_provenance.
- NP487137.RAZ7AlVlN1JrYti9ltPWbXHkwKuB0Kp-eGpoUi1HkVrzI130_assertion description "[Knockdown of integrin α(5) and RhoA attenuated fibrogenic, contractile, and migratory activities of IPF fibroblasts, in a manner similar to that observed with miR-31.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487137.RAZ7AlVlN1JrYti9ltPWbXHkwKuB0Kp-eGpoUi1HkVrzI130_provenance.
- NP487141.RAQqJjbxPr_uIsxcyeqpfx1jtYewX3fQhlbaDd69bvaZU130_assertion description "[Human Nude/SCID (severe combined immunodeficiency) is the first severe combined immunodeficiency caused by mutation of the winged-helix-nude (WHN) gene, which is expressed in the thymus but not in the hematopoietic lineage.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487141.RAQqJjbxPr_uIsxcyeqpfx1jtYewX3fQhlbaDd69bvaZU130_provenance.
- NP487143.RAW8vrcscl4BRlgxD3lF3YdMvBBnFjtGnVN0g6a8Ua3x4130_assertion description "[Single nucleotide polymorphisms (SNPs) in the progesterone receptor (PGR) gene have been associated with the risk of endometrial cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487143.RAW8vrcscl4BRlgxD3lF3YdMvBBnFjtGnVN0g6a8Ua3x4130_provenance.
- NP487144.RAa1gB6YigBOpW5tmIjYIlgiuN4ZD1HRH2_R9H0JMk-LU130_assertion description "[5), Huntington's disease (69.0) and spinal and bulbar muscular atrophy (16.3), which is consistent with the clinical observation that the genetic anticipation on the paternal transmission of DRPLA is the most prominent among CAG repeat diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487144.RAa1gB6YigBOpW5tmIjYIlgiuN4ZD1HRH2_R9H0JMk-LU130_provenance.
- NP487147.RAZLVY7zX--Irnbo3Ylre4F_n5uORtH3tI3fiTWZVQ3UY130_assertion description "[Combinations targeting ILK and components of the Ras/MAPK pathway result in synergy and could potentially be more effective against glioblastoma cancer than monotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487147.RAZLVY7zX--Irnbo3Ylre4F_n5uORtH3tI3fiTWZVQ3UY130_provenance.
- NP487156.RAZTVtkmUYqc61dQsgmdAhspz-vZs_LJBXC4CsjXmp5CQ130_assertion description "[The Enhancer of Zeste homologue2 gene (EZH2) is frequently expressed at high levels in malignant tumours, including bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487156.RAZTVtkmUYqc61dQsgmdAhspz-vZs_LJBXC4CsjXmp5CQ130_provenance.
- NP487157.RAbNznKZ94Oit0sOKrarIQAQpM-i-2GUUYA6Ekq-wH0kE130_assertion description "[These data suggest that miR-21 expression is increased in pancreatic cancer cells and that miR-21 contributes to the cell proliferation, invasion, and chemoresistance of pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487157.RAbNznKZ94Oit0sOKrarIQAQpM-i-2GUUYA6Ekq-wH0kE130_provenance.
- NP487160.RATz0JT6H6uE52K8UGv-ZuGVa8iFpFgBH4RDLlGQgMmzY130_assertion description "[In conclusion, these studies reveal that PAX3, PAX7 and their fusions with FKHR are each expressed in RMS tumors as a consistent mixture of functionally distinct isoforms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487160.RATz0JT6H6uE52K8UGv-ZuGVa8iFpFgBH4RDLlGQgMmzY130_provenance.
- NP487161.RATEYBWMYLaA1LyBISTDBmZlgF19VP4UkKTwogkRhAkHs130_assertion description "[Previous studies have demonstrated that susceptibility to experimentally induced SLE depended on the expression of MHC class I molecules: mice deficient in beta2-microglobulin did not express cell surface class I and were resistant to the induction of experimental SLE.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487161.RATEYBWMYLaA1LyBISTDBmZlgF19VP4UkKTwogkRhAkHs130_provenance.
- NP487162.RAauHqT3lZ0fvz4D-VQ94FcY9il9OwUIBcfSgyQbaJElw130_assertion description "[We find associations with the IRF8 region and the region containing CDH1 and CDH3, as well as substantial phenotypic and genetic heterogeneity for CD itself.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487162.RAauHqT3lZ0fvz4D-VQ94FcY9il9OwUIBcfSgyQbaJElw130_provenance.
- NP487170.RAcCXV-wr4FTfHiM1YjXNMg3gg3S19Hyj3ssu95Gj9CtQ130_assertion description "[p53 and proliferating cell nuclear antigen expression in JC virus-infected cells of progressive multifocal leukoencephalopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487170.RAcCXV-wr4FTfHiM1YjXNMg3gg3S19Hyj3ssu95Gj9CtQ130_provenance.
- NP487185.RAUyeYJjVqNY55HhhRhRh6sfWLP28zQxiMTed629HqkAU130_assertion description "[The three-dimensional structure result indicates that the nsp2 protein of GD strain is high homologous with 3CL(pro) of SARS-CoV urbani strain, 3CL(pro) of transmissible gastroenteritis virus and 3CL(pro) of human coronavirus 229E strain, which further suggests that nsp2 protein of GD strain possesses the activity of 3CL(pro).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487185.RAUyeYJjVqNY55HhhRhRh6sfWLP28zQxiMTed629HqkAU130_provenance.
- NP487186.RAW3oDsB2EfXGESyU3n-Cx-4lYRSl4jNgKHVL51_K6rLk130_assertion description "[Human GFRA1: cloning, mapping, genomic structure, and evaluation as a candidate gene for Hirschsprung disease susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487186.RAW3oDsB2EfXGESyU3n-Cx-4lYRSl4jNgKHVL51_K6rLk130_provenance.
- NP487190.RAd04LuKfa3vRZ8q1Ko8c_BUmMYXPHF8s_Zi_NW7LGtqM130_assertion description "[The coding region of NPY2R was analysed for mutations in 48 obese Danish white subjects and two silent substitutions were identified: SNPs 1 and 2 (rs1047214 and rs2880415).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487190.RAd04LuKfa3vRZ8q1Ko8c_BUmMYXPHF8s_Zi_NW7LGtqM130_provenance.
- NP487191.RAd5BcDVGF7V3WQJ5rjwI1BvOKSvyCOw7SXG51iqMrjx4130_assertion description "[As a candidate gene we further evaluated the expression of alpha(2)-zinc-glycoprotein 1 (AZGP1), a soluble protein that stimulates lipolysis, induces a reduction in body fat in mice, is associated with the cachexia related to cancer, and is known to be expressed in secretory cells of lung epithelium.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487191.RAd5BcDVGF7V3WQJ5rjwI1BvOKSvyCOw7SXG51iqMrjx4130_provenance.
- NP487195.RAZAjUqAt7OtkNiiSczVv5WFKjd2RYgS_wzLNExdnnBYw130_assertion description "[Although we only detected GSTP1 methylation in under one-third of voided urine samples, we have demonstrated that molecular diagnosis of prostate neoplasia in urine is feasible.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487195.RAZAjUqAt7OtkNiiSczVv5WFKjd2RYgS_wzLNExdnnBYw130_provenance.
- NP487197.RAdqI5wXZm5hyHzlNPhuL38AaJDN5Yd2_PC9BPKpjdQ8I130_assertion description "[Our immunohistochemistry assays of colorectal cancer revealed that heat shock protein (HSP) 27 overexpression relates to metastatic behavior of CRC cell.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487197.RAdqI5wXZm5hyHzlNPhuL38AaJDN5Yd2_PC9BPKpjdQ8I130_provenance.
- NP487200.RATx3TGkcI2WW7YIZQ4ehjMnVSeTQcmsTTcLc4i-Xgo-s130_assertion description "[The aims of our study were to clarify the relationship between TM4SF and pancreatic cancer and to determine the prognostic significance of TM4SF in human pancreatic cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487200.RATx3TGkcI2WW7YIZQ4ehjMnVSeTQcmsTTcLc4i-Xgo-s130_provenance.
- NP487204.RAf91_LPS73CPntCQIlNmhDBWcKQRQPD_mmyB4dM1TxR8130_assertion description "[Lastly, Rplp1 mRNA was found to be upregulated in 16 of 26 human colon cancer biopsy specimens, a finding that may be of relevance to cancer research.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487204.RAf91_LPS73CPntCQIlNmhDBWcKQRQPD_mmyB4dM1TxR8130_provenance.
- NP487206.RARfxT8F6yY7atXZGhNAjpzfUGGti3tSCfMA0E1YA68Q0130_assertion description "[In one family, the association of cortical dysplasia and congenital lymphedema have been related to mutations in the RELN gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487206.RARfxT8F6yY7atXZGhNAjpzfUGGti3tSCfMA0E1YA68Q0130_provenance.
- NP487207.RAUWw45OwUFmdjMHUEyPlwWCWEV9fmbUJ1xQBFfHnEaZs130_assertion description "[CREB/PKA sensitive signalling pathways activate and maintain expression levels of the hepatitis B virus pre-S2/S promoter.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487207.RAUWw45OwUFmdjMHUEyPlwWCWEV9fmbUJ1xQBFfHnEaZs130_provenance.
- NP487215.RARk4-bsscQ559KXfWELTucnE-e4NHJpJmoLu4NW5V2MI130_assertion description "[DNA mutations in the CLN1, CLN2, and CLN3 genes that underlie INCL (infantile NCL), LINCL, and JNCL (juvenile NCL), respectively, were studied with molecular analyses.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487215.RARk4-bsscQ559KXfWELTucnE-e4NHJpJmoLu4NW5V2MI130_provenance.
- NP487218.RAciLUHihaO6jehidkqOC1lUlJKRoUf57ZYs7R-3aiR_o130_assertion description "[Mutations of LAMB2 typically cause autosomal recessive Pierson syndrome, a disorder characterized by congenital nephrotic syndrome, ocular and neurologic abnormalities, but may occasionally be associated with milder or oligosymptomatic disease variants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487218.RAciLUHihaO6jehidkqOC1lUlJKRoUf57ZYs7R-3aiR_o130_provenance.
- NP487223.RAXuWi_GjERnZWXk3zKYEcQVedcW5mMYMCmkrofqjo6Fw130_assertion description "[We tested genomic instability in patients with myelodysplastic syndrome (MDS) by the comet assay and verified the suitability of this approach as a tool for analysis of ineffective hematopoiesis in refractory anemia (RA) and RA with ring sideroblasts (RARS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487223.RAXuWi_GjERnZWXk3zKYEcQVedcW5mMYMCmkrofqjo6Fw130_provenance.
- NP487231.RAanDpsoK4tzruU8hqJUMVoB3tOYQlXoW36tK0NgKmaHo130_assertion description "[Oophorectomy is associated with reduced risk of ovarian and fallopian tube cancer in high-risk women, although there is a substantial residual risk for peritoneal cancer in BRCA1 and BRCA2 mutation carriers following prophylactic salpingo-oophorectomy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487231.RAanDpsoK4tzruU8hqJUMVoB3tOYQlXoW36tK0NgKmaHo130_provenance.
- NP487233.RAQh3VYy24_6W_uBruuFFHXOxYbJPkCs4lmDziB3Bz0s0130_assertion description "[We examined, in 900 women from the Twins UK cohort, the relationship of carotid-femoral pulse wave velocity (cfPWV) to measures of atherosclerosis (carotid intima-media thickening; carotid/femoral plaque), calcification (calcified plaque [CP]; aortic calcification by computed tomography, performed in subsample of 40 age-matched women with low and high cfPWV), and BMD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487233.RAQh3VYy24_6W_uBruuFFHXOxYbJPkCs4lmDziB3Bz0s0130_provenance.
- NP487240.RAQu3RH3TYwBnhWAtEzjCBjkGKAkuMMQRM2qleXxFoFqM130_assertion description "[To reassess the biochemical features of MT6-MMP, we have expressed the MT6-MMP construct tagged with a FLAG tag in breast carcinoma MCF-7 and fibrosarcoma HT1080 cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487240.RAQu3RH3TYwBnhWAtEzjCBjkGKAkuMMQRM2qleXxFoFqM130_provenance.
- NP487245.RAXoLkehnwCefbdAw_eT2LZw1jU2UKue6Nkd0S0lKVYJo130_assertion description "[Saethre-Chotzen syndrome, a common autosomal dominant craniosynostosis in humans, is characterized by brachydactyly, soft tissue syndactyly and facial dysmorphism including ptosis, facial asymmetry, and prominent ear crura.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487245.RAXoLkehnwCefbdAw_eT2LZw1jU2UKue6Nkd0S0lKVYJo130_provenance.
- NP487247.RAR2tHfi9Pa1UK-EQlKeUv0YkDvNGg_E9ifQa7-wJzPAg130_assertion description "[Taken together these data suggest a so far unknown function of the RNA-binding protein La in promoting tumor progression of head and neck SCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487247.RAR2tHfi9Pa1UK-EQlKeUv0YkDvNGg_E9ifQa7-wJzPAg130_provenance.
- NP487255.RAeZLuBS6ZUcxQ1yEyr0huVReXO6v9pW_yT-hhEMLW-ic130_assertion description "[Rs11892031[A] on chromosome 2q37 in an intronic region of the UGT1A locus is associated with urinary bladder cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487255.RAeZLuBS6ZUcxQ1yEyr0huVReXO6v9pW_yT-hhEMLW-ic130_provenance.
- NP487257.RAUokrytvxz5NPNK_Tx4fzpUkY_DOS5IPyr85Md-baqsw130_assertion description "[A family-based association test (FBAT) was performed with both a quantitative measure of obesity [fat mass, lean mass, body mass index (BMI), and percentage fat mass (PFM)] and a dichotomously defined obesity phenotype-OB (OB if BMI > or = 30 kg/m(2)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487257.RAUokrytvxz5NPNK_Tx4fzpUkY_DOS5IPyr85Md-baqsw130_provenance.
- NP487259.RAV2lDwY4vUnKDnHZXorrn0SN8jXuoP_jGCWzo9ayr_yA130_assertion description "[Comparison of the transcriptional profile of PCNSL with various normal and neoplastic B-cell subsets demonstrated PCNSL (i) to display gene expression patterns most closely related to late germinal center B cells, (ii) to display a gene expression profile similar to systemic diffuse large B-cell lymphomas (DLBCLs) and (iii) to be in part assigned to the activated B-cell-like (ABC) or the germinal center B-cell-like (GCB) subtype of DLBCL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487259.RAV2lDwY4vUnKDnHZXorrn0SN8jXuoP_jGCWzo9ayr_yA130_provenance.
- NP487261.RAVz6zPgpj2O4swUNG-D7Nf5LCQuTwni_aeuf3fcXm75s130_assertion description "[Causes of aborted SCD/SUD were myocardial infarction (n = 2), idiopatic ventricular fibrillation (n = 1), and the Brugada syndrome (n = 1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487261.RAVz6zPgpj2O4swUNG-D7Nf5LCQuTwni_aeuf3fcXm75s130_provenance.
- NP487262.RAbezD2Ojt_bglrF6BDp_c9r8LZIGmIVL1NslA2qsKmco130_assertion description "[Sequence comparison revealed highest homology with the RET sequence previously identified in mouse myeloma SP2/0-AG14 cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487262.RAbezD2Ojt_bglrF6BDp_c9r8LZIGmIVL1NslA2qsKmco130_provenance.
- NP487268.RAQRIjrF_s4fMRu18ix4hIP3I9bTgAq7xIume4Mo1W4RU130_assertion description "[For overall survival, size, nuclear grade, MIB-1 <10% (p = 0.0167), pathologic stage group, metastasis, and combined score (p = 0.0456) were pronounced on univariate analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487268.RAQRIjrF_s4fMRu18ix4hIP3I9bTgAq7xIume4Mo1W4RU130_provenance.
- NP487269.RAVC-26FS5xAK5tXTjz4yhxn4doJfAIB6BOduCkD1PUDs130_assertion description "[Mutations in the gene-encoding Na(v)1.5, SCN5A, have been associated with a variety of arrhythmic disorders, including long QT, Brugada, and sick sinus syndromes as well as progressive cardiac conduction defect and atrial standstill.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487269.RAVC-26FS5xAK5tXTjz4yhxn4doJfAIB6BOduCkD1PUDs130_provenance.
- NP487270.RAZA4FPICdsaGvfMbDAmy0zTTcW3pPhxUZyGYTL36bXr8130_assertion description "[The impact on metastasis was assessed, the expressions of VEGF/bFGF in hepatoma tissues and in murine sera were evaluated, and the micro-vessel density (MVD) was counted as well.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487270.RAZA4FPICdsaGvfMbDAmy0zTTcW3pPhxUZyGYTL36bXr8130_provenance.
- NP487272.RAUky71HIgcHUUItx3-tuqZlA_rbp4ynBxd6-XzKwniPM130_assertion description "[To evaluate the association of TSPY1 with the tumor, we developed an interphase fluorescent in situ hybridization assay that uses probes that target the region of the GBY locus that contains TSPY1 and a commercially available chromosome X CEP probe.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487272.RAUky71HIgcHUUItx3-tuqZlA_rbp4ynBxd6-XzKwniPM130_provenance.
- NP487273.RAXWteLdDjOCk34bF1FyAiAaIQDCtvouSGdkqlBsNuIpk130_assertion description "[We found LOH at HIPK-2 gene locus in 37.5% of PTCs, 14.3% of FTCs and 18.2% of follicular adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487273.RAXWteLdDjOCk34bF1FyAiAaIQDCtvouSGdkqlBsNuIpk130_provenance.
- NP487274.RAZg6h4jiuvILiUuRr0RtVnYsMsEScs-nypFFJzMohvII130_assertion description "[This study examined the effects of exogenous human leptin on estrogen receptor (ER) alpha and beta in human breast tumor tissue in a nude mouse xenograft model.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487274.RAZg6h4jiuvILiUuRr0RtVnYsMsEScs-nypFFJzMohvII130_provenance.
- NP487287.RARCV9dGD2OAs8w87WqrWiJggM-VGwV07Go6q9g17kZWM130_assertion description "[In most IPF cases herein investigated, epithelial cells expressing deltaN-p63 were observed at sites of abnormal proliferation at the bronchiolo-alveolar junctions, characterized by epithelial hyperplasia, squamous metaplasia, bronchiolization, and abnormal p53 nuclear accumulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487287.RARCV9dGD2OAs8w87WqrWiJggM-VGwV07Go6q9g17kZWM130_provenance.
- NP487288.RAZetKlh855Lrv5jFOnGK-vdshamhYlT7WiUQTpe_1ma8130_assertion description "[Transcriptional activation of the Axl and PDGFR-α by c-Met through a ras- and Src-independent mechanism in human bladder cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487288.RAZetKlh855Lrv5jFOnGK-vdshamhYlT7WiUQTpe_1ma8130_provenance.
- NP487289.RATKFErGt1ZFJ9j03cYa4BzrIM9pxp_ysJfskGwxDvC-s130_assertion description "[Homozygosity for a nonsense mutation in CTNS (753G -->A), encoding a premature termination codon (PTC) at amino acid 138 (W138X), results in nephropathic cystinosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487289.RATKFErGt1ZFJ9j03cYa4BzrIM9pxp_ysJfskGwxDvC-s130_provenance.
- NP487291.RAbWG6_KQgreVzeooXNLqvSpKFndVr9KbibZeGjH1hRpQ130_assertion description "[Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487291.RAbWG6_KQgreVzeooXNLqvSpKFndVr9KbibZeGjH1hRpQ130_provenance.
- NP487296.RARitv0InWWwYJ0Foo3e3M20rNEe7jN5jMs1CTBn8_Uas130_assertion description "[The half-normal activity of human PBGD causes acute intermittent porphyria (AIP), an autosomal dominant inherited disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487296.RARitv0InWWwYJ0Foo3e3M20rNEe7jN5jMs1CTBn8_Uas130_provenance.
- NP487298.RAcJ2hc8zC2fYEeNv7WSRuChbZKQ3Fi5tdlEoDKGuwKtA130_assertion description "[SCA2 and SCA3 mutations in young-onset dopa-responsive parkinsonism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487298.RAcJ2hc8zC2fYEeNv7WSRuChbZKQ3Fi5tdlEoDKGuwKtA130_provenance.
- NP487299.RAVhpQAJbuf2CNRYLv7vTemaIozbeUXm0U_BxXo16p05w130_assertion description "[Transcription of SOCS1, SOCS2, CDKN2a, and RASSF1a genes was significantly reduced in fresh melanoma samples, while MGMT showed a 12-fold upregulation at the messenger ribonucleic acid level (P < 0.001).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487299.RAVhpQAJbuf2CNRYLv7vTemaIozbeUXm0U_BxXo16p05w130_provenance.
- NP487302.RASB0n15Gcd-2VWLiiKufNgCWqUyZiXKnNRO9_7hCnvso130_assertion description "[The phenotype maps on chromosome 2q34-q36 and was designated as SD1 (ie syndactyly 1).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487302.RASB0n15Gcd-2VWLiiKufNgCWqUyZiXKnNRO9_7hCnvso130_provenance.
- NP487305.RAbachZDSWtBrfhlIqNQQbV0i1d62Ho6Pg-58g0egFqVo130_assertion description "[Finally, the optimized and validated QEXT assay correctly distinguished normal placentas from trisomy 21 placentas in tests of the following clinically relevant combinations: diploid homozygous (CC), diploid heterozygous (AC), triploid homozygous (AAA), and triploid heterozygous (AAC or ACC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487305.RAbachZDSWtBrfhlIqNQQbV0i1d62Ho6Pg-58g0egFqVo130_provenance.
- NP487309.RAalM_wRJWtG-v3CcKqC-k2ux4ckfg66jWAhZ2mVYBypo130_assertion description "[Further studies are required on other more prevalent genetic variants of RAGE and cardiovascular disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487309.RAalM_wRJWtG-v3CcKqC-k2ux4ckfg66jWAhZ2mVYBypo130_provenance.
- NP487311.RAc2CfntlH1orXq14uhvw_aXbBj1PgLxYty59SjhyvWKg130_assertion description "[PON1 and LCAT as well as HDL constituent apolipoprotein (apo) AI and apo AII, were altered significantly in RA patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487311.RAc2CfntlH1orXq14uhvw_aXbBj1PgLxYty59SjhyvWKg130_provenance.
- NP487316.RAYmPEaxFcL7nZHfcbh8Fpg5rexqCJLIi2DTAtoL3dfjg130_assertion description "[We recently showed platelets can contribute to the pathophysiology of inflammatory arthritis via IL-1- containing microparticles.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487316.RAYmPEaxFcL7nZHfcbh8Fpg5rexqCJLIi2DTAtoL3dfjg130_provenance.
- NP487319.RAbXRt6T5L06pX3Zr_8FyLZqanYQFCw46bxzvVdQHLtFQ130_assertion description "[Recently it was reported that plasminogen activator inhibitor type one (PAI-1) inactivation can alleviate the symptoms of Alzheimer's disease and reduce the body weight of obese individuals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487319.RAbXRt6T5L06pX3Zr_8FyLZqanYQFCw46bxzvVdQHLtFQ130_provenance.
- NP487320.RAbwEqm7vzBCc5Bn8a_D3mhCMwkUYO2i1mZWq1YdVxX_I130_assertion description "[It became evident in recent years that mutations in the COL4A3 or the COL4A4 gene can give rise not only to autosomal recessive ATS syndrome, in which males and females are severely affected, but also to an autosomal dominant form, where the clinical progression towards impaired renal function can be very slow and also to benign familial hematuria (BFH) in which renal function is preserved.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487320.RAbwEqm7vzBCc5Bn8a_D3mhCMwkUYO2i1mZWq1YdVxX_I130_provenance.
- NP487323.RAf5yJV797avGnXQZcaOoMy5AkHfc0nqmbyBQJYxwsYl8130_assertion description "[Rottlerin induces heme oxygenase-1 (HO-1) up-regulation through reactive oxygen species (ROS) dependent and PKC delta-independent pathway in human colon cancer HT29 cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487323.RAf5yJV797avGnXQZcaOoMy5AkHfc0nqmbyBQJYxwsYl8130_provenance.
- NP487324.RAfFeVyaxq1GJ6IfCCIyyBtPdBxxyYAUW82Hv7NRUDnRk130_assertion description "[Acquired somatic uniparental disomy (UPD) is commonly observed in myelodysplastic syndromes (MDS), myelodysplastic/myeloproliferative neoplasms (MDS/MPN), or secondary acute myelogenous leukemia (sAML) and may point toward genes harboring mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487324.RAfFeVyaxq1GJ6IfCCIyyBtPdBxxyYAUW82Hv7NRUDnRk130_provenance.
- NP487328.RAcUFpG74ZiGt2c2ngs2_o4Qy23tfziVqiMX0OzyyBmIc130_assertion description "[Furthermore, isolated microvascular endothelial cells (MVECs) from 4 patients with diffuse cutaneous SSc (dcSSc) and 3 controls were analyzed for SDF-1 and CXCR4 by confocal laser scanning microscopy, RT-PCR, and Western blotting.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487328.RAcUFpG74ZiGt2c2ngs2_o4Qy23tfziVqiMX0OzyyBmIc130_provenance.
- NP487329.RATtGQtMecLQNa8lFSjFwu8yJObkbmuOy9ldEhX5lX7Bk130_assertion description "[Statistically significant association with melanoma risk was also observed for the carriers of the variant T-allele of rs3088440 (540 C>T) at the 3' UTR of CDKN2A gene with an OR 1.52 (95% CI 1.14-2.04).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP487329.RATtGQtMecLQNa8lFSjFwu8yJObkbmuOy9ldEhX5lX7Bk130_provenance.