Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP489402.RAb3rvfUdALu3-hedJkjQQb3dwIOm24B-a2ZwEp8cDvI8130_assertion description "[The molecular pathology of MITF/microphthalmia mutations appears to be different in humans and mice, with gene dosage having more significant effects in humans than in the mouse.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489402.RAb3rvfUdALu3-hedJkjQQb3dwIOm24B-a2ZwEp8cDvI8130_provenance.
- NP489404.RATOzmpgSbiHzF1OQItYxG4W6W6Nbllg0ScXa6ezNHACk130_assertion description "[To address a potential role for p53, Bcl2 associated protein X (Bax), and apoptosis in the processes associated with cell turnover during cystic medial degeneration (CMD) of the aorta.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489404.RATOzmpgSbiHzF1OQItYxG4W6W6Nbllg0ScXa6ezNHACk130_provenance.
- NP489408.RAZNNh7xonUgkTl5I_eI5sW-rtpvdYZ4gPdYiIY7HhFao130_assertion description "[We aimed at determining the frequency of c-KIT expression and mutations in a series of 109 CRC cases (73 primary tumours and 36 lymph node metastases) characterised for KRAS and BRAF mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489408.RAZNNh7xonUgkTl5I_eI5sW-rtpvdYZ4gPdYiIY7HhFao130_provenance.
- NP489411.RAdhEtoyMYzcaoNxAlcWVAkl0Sx8kwiSz-eRdjnIct-R8130_assertion description "[These results identify a BAP1-related cancer syndrome that is characterized by mesothelioma and uveal melanoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489411.RAdhEtoyMYzcaoNxAlcWVAkl0Sx8kwiSz-eRdjnIct-R8130_provenance.
- NP489413.RAXxYeKroaxPaoiNfpY2vZZGiNdttHd1nT9ORYkqgV3SQ130_assertion description "[Their cytotoxicity against colon cancer was mainly ascribed to peptide-specific and CD8+ CTLs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489413.RAXxYeKroaxPaoiNfpY2vZZGiNdttHd1nT9ORYkqgV3SQ130_provenance.
- NP489414.RAfbYs2Yc42h-73bJA9oeSDlrHRBq8J4-VHpZMwLVTPI0130_assertion description "[We detected no genome-wide significant association signals for CP; however, we found suggestive evidence of association (P < 5 × 10(-6)) for six loci, including NIN, NPY, WNT5A for severe CP and NCR2, EMR1, 10p15 for moderate CP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489414.RAfbYs2Yc42h-73bJA9oeSDlrHRBq8J4-VHpZMwLVTPI0130_provenance.
- NP489417.RAUZwegrhNXZykhUkca8DryfOKdTZIUIWle3FpokQ8mJQ130_assertion description "[Demographic and clinical characteristics associated with hepatic steatosis in patients with chronic hepatitis C including older age, higher BMI, more genotype 3 infection, and higher mean serum levels of triglyceride, alanine aminotransferase and γ-glutamyl transpeptidase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489417.RAUZwegrhNXZykhUkca8DryfOKdTZIUIWle3FpokQ8mJQ130_provenance.
- NP489421.RATZ37kw8948hd5Gt6Nwyv5qXtcvADauA5pLYh3nG8UTs130_assertion description "[We therefore investigated the expression of genes coding for major inward and outward ion channels, calcium binding proteins, ion receptors, ion exchangers, calcium ATPases, and calcium/calmodulin-dependent protein kinases in explanted hearts (n=13) of patients diagnosed with end-stage heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489421.RATZ37kw8948hd5Gt6Nwyv5qXtcvADauA5pLYh3nG8UTs130_provenance.
- NP489422.RAfHmy_FQyCtx4svls5lfxOI2E4UBnVW-oEaXDJVwqVqQ130_assertion description "[Moreover, SeV vectors significantly induced BDNF expression, ameliorating synaptic degeneration and memory deficits in a transgenic mouse model of AD (Tg2576).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489422.RAfHmy_FQyCtx4svls5lfxOI2E4UBnVW-oEaXDJVwqVqQ130_provenance.
- NP489427.RAY2gEEKwjzoQRYXB5FhoFR_BwuBcf-dxv6iN96ehAgWE130_assertion description "[The results indicated that overexpression of PRDX3 was associated with 94.9% HCC, and correlated with poor differentiation (P<0.05), which suggest that PRDX3 has substantial clinical impact on the progression of hepatocarcinoma, and may be a potential therapeutic target for HCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489427.RAY2gEEKwjzoQRYXB5FhoFR_BwuBcf-dxv6iN96ehAgWE130_provenance.
- NP489429.RAT5aEHNleiEEgg4iN5crp9H--7p60L_u7AKP6sf2NEbA130_assertion description "[Ocular involvement in primary antiphospholipid syndrome. Ocular involvement in primary APS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489429.RAT5aEHNleiEEgg4iN5crp9H--7p60L_u7AKP6sf2NEbA130_provenance.
- NP489430.RAbljfCeTTrxZrk-S69BOviMO99kr4vDpZfOxDgwJyZeQ130_assertion description "[Our meta-analysis showed that human leucocyte antigens HLA-DQB1*0201 (OR=2.64, P=0.018), DQB1*0303 (OR=1.93, P=0.008), and DRB1*0901 (OR=2.14, P=0.002) alleles and HLA-A1 (OR=5.10, P=0.001), A2 (OR=2.17, P=0.005), B5 (OR=4.63, P=0.001), B8 (OR=2.99, P=0.02), and B12 (OR=5.49, P=0.005) serotypes enhanced susceptibility to PSHD, whereas HLA-DQA1*0501 (OR=0.29, P≤0.001) and DQB1*0301 (OR=0.58, P=0.007) were protective factors against the disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489430.RAbljfCeTTrxZrk-S69BOviMO99kr4vDpZfOxDgwJyZeQ130_provenance.
- NP489433.RAXqIDiwvLXLblQLW4udKLSDvbmFqpr_kReqcqbbbmgEc130_assertion description "[Factors influencing the outcome of anti-VEGF treatment in neovascular AMD are still investigated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489433.RAXqIDiwvLXLblQLW4udKLSDvbmFqpr_kReqcqbbbmgEc130_provenance.
- NP489436.RATHdcgtWKnyUAWU6l7c7YQAm2X0fHb13H5RD6hY4mwVY130_assertion description "[We recently reported that a single nucleotide polymorphism (SNP) rs2596542 located in the MICA promoter region was significantly associated with the risk for hepatitis C virus (HCV)-induced hepatocellular carcinoma (HCC) and also with serum levels of soluble MICA (sMICA).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489436.RATHdcgtWKnyUAWU6l7c7YQAm2X0fHb13H5RD6hY4mwVY130_provenance.
- NP489438.RASo0ReZom0MOZiRNnhyIJzaOpY4mB3zvWIqH4MkJ7Tf0130_assertion description "[Immunohistochemical analyses were performed for RUNX3, E-cadherin, N-cadherin and TWIST1 in 33 human HCC tissues, also divided into low- and high-EMT HCC, based on TWIST1 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489438.RASo0ReZom0MOZiRNnhyIJzaOpY4mB3zvWIqH4MkJ7Tf0130_provenance.
- NP489439.RAQZUrARmN8A-5JkvQ-u0QBN0JsBkVo2SSa81xg2J0VOM130_assertion description "[In summary, our study proves HMG1 and p65 to be important factors in MIA regulation and melanoma progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489439.RAQZUrARmN8A-5JkvQ-u0QBN0JsBkVo2SSa81xg2J0VOM130_provenance.
- NP489443.RAYkYXADcT_izCFsN3aOQV_2KZzx_z-NcOCxSnTKdy8Ck130_assertion description "[Although none of these were found in 100 normal-weight white control subjects, L73P in PYY and F87I and A172T in Y2R did not segregate with obesity in family studies, and family data were unavailable for IVS2 + 32delG in PYY and L40F in Y2R.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489443.RAYkYXADcT_izCFsN3aOQV_2KZzx_z-NcOCxSnTKdy8Ck130_provenance.
- NP489449.RAYFEMtNDvv16UjCMVaFrD48tXekA1VClYMuaJDQPSy_0130_assertion description "[Therefore, the DeltaS6 mutation may cause XLRP because it prevents normal amounts of RP2 reaching the correct cellular locale, whereas the R118H mutation is in a region of the protein that is vital for another aspect of RP2 function in the retina.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489449.RAYFEMtNDvv16UjCMVaFrD48tXekA1VClYMuaJDQPSy_0130_provenance.
- NP489450.RAbSY5CZ0B6KJoZoRqoBaSb0gq3KiW1tHPEh09lTZwdRg130_assertion description "[Two and 18 additional SNPs in GABRA4 and GABRA2, respectively, were associated with nicotine dependence.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489450.RAbSY5CZ0B6KJoZoRqoBaSb0gq3KiW1tHPEh09lTZwdRg130_provenance.
- NP489454.RAYrPINB7OYTMV0yrRW0U3WYVRTg9HkX1emYDyserbUJE130_assertion description "[In pregnant animals, these responses are exaggerated by moderate undernutrition and are mediated by reduced tissue sensitivity and responsiveness to insulin, associated with decreased tissue expression of the insulin-responsive facilitative glucose transporter, GLUT4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489454.RAYrPINB7OYTMV0yrRW0U3WYVRTg9HkX1emYDyserbUJE130_provenance.
- NP489456.RAcyDGaIH_1dg4hrSjDeq52tGoa0e_x1JiGlnDi7yjiqI130_assertion description "[Pharmacologic inhibition of sAC did not alter IOP or C(t) in sAC-deficient mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489456.RAcyDGaIH_1dg4hrSjDeq52tGoa0e_x1JiGlnDi7yjiqI130_provenance.
- NP489463.RAYpWNlVWKDf1vpoNUF_66nH8v4boLBEmOKe8Z1CaTvkc130_assertion description "[Impact: Additional research is warranted to determine the mechanism of GC genotype in influencing 25(OH)D concentrations and to further elucidate the role of CASR in colorectal neoplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489463.RAYpWNlVWKDf1vpoNUF_66nH8v4boLBEmOKe8Z1CaTvkc130_provenance.
- NP489468.RAfSP8jfgGQXy4iLEuAulxA4-FdB8EdFJ7uHa2Su_LHb8130_assertion description "[Evidence suggests that an increased NADH/NAD(+) ratio generated by reduced flux through the respiratory chain inhibits beta-oxidation, producing secondary carnitine deficiency while increasing reactive oxygen species and depleting alpha-tocopherol (alpha-TOC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489468.RAfSP8jfgGQXy4iLEuAulxA4-FdB8EdFJ7uHa2Su_LHb8130_provenance.
- NP489470.RAUCFLHJZeL1snUH-_r4_XAJ7CpZ1myC56r1LrDdB05TU130_assertion description "[Brain MRI in neurodegeneration with brain iron accumulation with and without PANK2 mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489470.RAUCFLHJZeL1snUH-_r4_XAJ7CpZ1myC56r1LrDdB05TU130_provenance.
- NP489473.RAcqtIh6tMJ4fNNa-lZ9_Tr6Otyr6qeqeVE4y8J3z9UZc130_assertion description "[Loss of heterozygosity of BRCA1, BRCA2 and ATM genes in sporadic invasive ductal breast carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489473.RAcqtIh6tMJ4fNNa-lZ9_Tr6Otyr6qeqeVE4y8J3z9UZc130_provenance.
- NP489474.RAR9wdSTQ-86ThnBRETts-AMI8eTZLN_HhEfZPqOFQltU130_assertion description "[Infants were tested after sedation with chloral hydrate, and monitored with ECG and transcutaneous oxygen and CO2 monitors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489474.RAR9wdSTQ-86ThnBRETts-AMI8eTZLN_HhEfZPqOFQltU130_provenance.
- NP489478.RAcQgmCYv7sgwqbqcLyGwTQq2H__We9zQG-EaO-MGdLqU130_assertion description "[The results indicate that VHL gene inactivation contributed to the oncogenesis of endolymphatic sac tumor and provide molecular genetic proof that this tumor is associated with VHL disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489478.RAcQgmCYv7sgwqbqcLyGwTQq2H__We9zQG-EaO-MGdLqU130_provenance.
- NP489486.RATeokM4U7ypldEp4vfC568QlU_nyo-rr8_65_BjiZisY130_assertion description "[We herewith report on a patient suffering from HER2 overexpressing MBC who received intrathecal methotrexate and trastuzumab for meningeal carcinomatosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489486.RATeokM4U7ypldEp4vfC568QlU_nyo-rr8_65_BjiZisY130_provenance.
- NP489488.RAY1OpsslGB8kDpNsK0KTZX8ehAJ6hDSaHaWHIEbpqlcY130_assertion description "[An infant with ambiguous genitalia was found to have a karyotype 45,X/46,X,r(Y)(p11.2;q11.23)/47,X,idic(Y)(p11.2),idic(Y)(p11.2) using G-banding, C-banding and FISH.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489488.RAY1OpsslGB8kDpNsK0KTZX8ehAJ6hDSaHaWHIEbpqlcY130_provenance.
- NP489491.RAWSsu9P4loKeqGzZdb5_DI2ZnQ61pn-ZG6ccBRXddCdk130_assertion description "[A role for NOS3 in onset of essential hypertension (HT) is, however, controversial.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489491.RAWSsu9P4loKeqGzZdb5_DI2ZnQ61pn-ZG6ccBRXddCdk130_provenance.
- NP489492.RAevJiUTgur5uHfTKejfrAITr9JCb8lizoNKQ2xQ1nnL0130_assertion description "[The map encompasses all the candidate loci of Bardet-Biedle syndrome type I (BBS1) and spinocerebellar ataxia type 5 (SCA5), one-third of the distal region for hereditary paraganglioma 2 (PGL2), and one-third of the central region for insulin-dependent diabetes mellitus 4 (IDDM4).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489492.RAevJiUTgur5uHfTKejfrAITr9JCb8lizoNKQ2xQ1nnL0130_provenance.
- NP489497.RAQbTjG5al_NexiqxTq6U-XqWMZC1DGq3pPffCeG70cIU130_assertion description "[Genotype FGB -455G>A (rs1800790) was associated with CRP elevations (≥ 10 mg/l) in both cohorts (RA, OR per allele 0.69, p=0.0007/P(adj)<0.015; non-RA, OR 0.70, p=0.0004/p(adj)<0.02; combined, OR 0.69, p<10(-5)/p(adj)=0.001).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489497.RAQbTjG5al_NexiqxTq6U-XqWMZC1DGq3pPffCeG70cIU130_provenance.
- NP489501.RAXoj4TTt1bhV0fLGd2OhqC-eF-7H0PwwSqmw9fjk8o0U130_assertion description "[We previously reported that a deficient form of the C4B gene, termed the C4B null allele (no C4B protein produced) had an increased frequently in autism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489501.RAXoj4TTt1bhV0fLGd2OhqC-eF-7H0PwwSqmw9fjk8o0U130_provenance.
- NP489505.RARMFVG3WN5ngkfuOljI04kT8YSsbZ4EmSuABZbv5C7VM130_assertion description "[NORE1B, a candidate tumor suppressor, is epigenetically silenced in human hepatocellular carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489505.RARMFVG3WN5ngkfuOljI04kT8YSsbZ4EmSuABZbv5C7VM130_provenance.
- NP489507.RAQMi8ZpuAmSymgyA_Z1x7iaotfvXXIhu_kLu2zVuvIsw130_assertion description "[In this study, we evaluated the association between genetic variation in BMP1 (11 tagSNPs), BMP2 (5 tagSNPs), BMP4 (3 tagSNPs), BMPR1A (9 tagSNPs), BMPR1B (21 tagSNPs), BMPR2 (11 tagSNPs) and GDF10 (7 tagSNPs) with risk of colon and rectal cancer and tumor molecular phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489507.RAQMi8ZpuAmSymgyA_Z1x7iaotfvXXIhu_kLu2zVuvIsw130_provenance.
- NP489508.RAZ8XNx6wgt_BB5si6ZmtVj6WRc0g39u9kRqtzVohldf8130_assertion description "[Molecular characterization revealed that, in addition to the pre-existing ESBL production (CTX-M-3 and SHV-5) and OmpK35 deficiency found in Lkp11-13, Lkp14 had acquired an extra plasmid-mediated AmpC beta-lactamase gene (blaDHA-1) and failed to express OmpK36, because of insertional inactivation by an insertion sequence IS5.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489508.RAZ8XNx6wgt_BB5si6ZmtVj6WRc0g39u9kRqtzVohldf8130_provenance.
- NP489510.RARhL2NM93PTktqz0lt8wQnnVargqNX0hmIPcXIiozOBw130_assertion description "[In the present study, 77 pairs of breast tumor and adjacent non-tumorous tissue samples were analyzed by polymerase chain reaction-single-strand conformational polymorphism, restriction fragment length polymorphism, and sequencing to evaluate the frequency of D310 (PCT) mutations and its association with clinicopathologic parameters of breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489510.RARhL2NM93PTktqz0lt8wQnnVargqNX0hmIPcXIiozOBw130_provenance.
- NP489512.RAcDOUyILNngjsOf1IdLx1w0sHgiumXmFPDkUlZzFxnRI130_assertion description "[Amplification of this region had not previously been associated with sarcoma development, but occasional amplification of CACY/S100A6 and MUC1 in 1q21 had been reported for melanoma and breast carcinoma respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489512.RAcDOUyILNngjsOf1IdLx1w0sHgiumXmFPDkUlZzFxnRI130_provenance.
- NP489528.RAXMsN4qgCn3hg99cDny7F_fmXrgBohv050vyarN7tQ1I130_assertion description "[These findings suggest that mammalian MLL3 and MLL4 function in the regulation of enhancer activity and that mutations of MLL3 and MLL4 that are found in cancers could exert their properties through malfunction of these Trr/MLL3/MLL4-specific (Trrific) enhancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489528.RAXMsN4qgCn3hg99cDny7F_fmXrgBohv050vyarN7tQ1I130_provenance.
- NP489530.RAdEzhX1Kn1u4WRkbsobp4o2M23NuY1Ur-YU1BuyFymk0130_assertion description "[Notch signaling is critically important for proper architecture of the vascular system, and mutations in NOTCH3 are associated with CADASIL, a stroke and dementia syndrome with vascular smooth muscle cell (VSMC) dysfunction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489530.RAdEzhX1Kn1u4WRkbsobp4o2M23NuY1Ur-YU1BuyFymk0130_provenance.
- NP489532.RAf6DVENxrf3k6C5p7whhsuqhe9-Zpyar4YRJn9tliDrE130_assertion description "[The term vulvar intraepithelial neoplasia (VIN) introduced in 1986 incorporates 3 grades of usual VIN (u-VIN I-III) and the differentiated VIN (d-VIN).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489532.RAf6DVENxrf3k6C5p7whhsuqhe9-Zpyar4YRJn9tliDrE130_provenance.
- NP489533.RAUNWrjcxHlFnTZ7cpfFafXAAQb-ZTTlnrXLkSfD8jUQY130_assertion description "[Therefore, 746 HIV-1-infected persons were examined for associations of previously described stromal cell-derived factor 1 (SDF-1) chemokine and CCR5 and CCR2 chemokine receptor gene variants with the risk of B-cell non-Hodgkin's lymphoma (NHL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489533.RAUNWrjcxHlFnTZ7cpfFafXAAQb-ZTTlnrXLkSfD8jUQY130_provenance.
- NP489534.RAVwSAQ722l5buYQlxDHC12antI5n6oqVzDHWdcf_mHpM130_assertion description "[Immunological response after WT1 mRNA-loaded dendritic cell immunotherapy in ovarian carcinoma and carcinosarcoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489534.RAVwSAQ722l5buYQlxDHC12antI5n6oqVzDHWdcf_mHpM130_provenance.
- NP489536.RAeVa_qd0HK2dP-DN38UQ_94lhfittCOh8Ni794PHNWJQ130_assertion description "[The pp32r1 mutation could thus be causally associated with the neoplastic growth properties of PC-3, and be of potential clinical significance.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489536.RAeVa_qd0HK2dP-DN38UQ_94lhfittCOh8Ni794PHNWJQ130_provenance.
- NP489539.RATMEN_Ze4yPgB0AP51gWiYcwqJuLLyjFSYhoCmZEuJaU130_assertion description "[The participation of other MALT1 gene translocations in PCMZL pathogenesis seems also unlikely.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489539.RATMEN_Ze4yPgB0AP51gWiYcwqJuLLyjFSYhoCmZEuJaU130_provenance.
- NP489540.RAdgH3gDt_L9qLGHQxVuzhkw6BkPoL1qvq7BOaca36fuE130_assertion description "[We used tissue microarray and immunohistochemistry to examine PUMA expression in 107 primary melanomas, 51 metastatic melanomas, and 64 dysplastic nevi.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489540.RAdgH3gDt_L9qLGHQxVuzhkw6BkPoL1qvq7BOaca36fuE130_provenance.
- NP489545.RAVsTiC9C5zEgLbj9rQ4oxcH_SV0QCLHqaSWjso83EjpY130_assertion description "[We hypothesize that either the low activity allele of catechol-O-methyltransferase is a risk factor for bipolar affective disorder in Chinese populations or is in linkage disequilibrium with a nearby susceptibility gene or polymorphism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489545.RAVsTiC9C5zEgLbj9rQ4oxcH_SV0QCLHqaSWjso83EjpY130_provenance.
- NP489548.RATtoggEfRjhhsABQNpbQqr5vqHRtpxqegFzuUGQiSQ9o130_assertion description "[Although no significant case-control differences in frequency of associated GG(-1575)CC(-1306)TT(-790) MMP-2 promoter genotype were observed, the genotype was found to be significantly less frequent in patients with family history of psoriasis (close as well as distant), family history of diabetes and personal history of allergy (2/11 vs. 55/32, odds ratio (OR) for GGCCTT 0.11, 95% confidential interval 0.02-0.50, Pcorr = 0.01).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489548.RATtoggEfRjhhsABQNpbQqr5vqHRtpxqegFzuUGQiSQ9o130_provenance.
- NP489549.RAegXYqPRN29BkKBCUxr82l2hqiX1VUc6jUjRlFDzJJxw130_assertion description "[In the present study we genotyped two clinically well-defined cohorts of Caucasian sarcoidosis patients from different European countries (each with their own controls) for the following polymorphisms using SSP-PCR: IL6 -174(G/C), IL6 intron 4(A/G) and IL1A-889(C/T).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489549.RAegXYqPRN29BkKBCUxr82l2hqiX1VUc6jUjRlFDzJJxw130_provenance.
- NP489553.RAaScBlVuL9F7n9XaRdx6YhXEC8ctmPMy9VL0VHywawq8130_assertion description "[NEK8/NPHP9 is a ciliary kinase associated with two renal ciliopathies in humans and mice, nephronophthisis (NPHP) and polycystic kidney disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489553.RAaScBlVuL9F7n9XaRdx6YhXEC8ctmPMy9VL0VHywawq8130_provenance.
- NP489559.RAdF7v6dh8NQVmMefAnhxgYy9pquWq5G72ClDjZM0OSMk130_assertion description "[The number of CD20 and CD138 cells was evaluated, and the presence and abundance of the chemokines macrophage inflammatory protein (MIP)-3alpha, CXCL9, CXCL10, CXCL11, CXCL12, and their receptors CCR-6, CXCR3, and CXCR4 were examined.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489559.RAdF7v6dh8NQVmMefAnhxgYy9pquWq5G72ClDjZM0OSMk130_provenance.
- NP489564.RAdBjMbagUqHPFTNzvGlEMzj2YiJWoKiQLV-kq1tAZQg8130_assertion description "[In laboratory models, downstream post-transcriptional modifiers such as TWIST and SNAIL contribute to the dissociation of the intracellular component of the cadherin-catenin complex (CCC), resulting in tumor progression and invasion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489564.RAdBjMbagUqHPFTNzvGlEMzj2YiJWoKiQLV-kq1tAZQg8130_provenance.
- NP489571.RAXIWT9HkzUBP7GXAZIDAZ54zwbEx9LMU-XU2c4AnWweA130_assertion description "[Protein-tyrosine phosphatase sigma is associated with ulcerative colitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489571.RAXIWT9HkzUBP7GXAZIDAZ54zwbEx9LMU-XU2c4AnWweA130_provenance.
- NP489575.RAW7uYkK7FIeTeH1Bz8Tpma52lFf9KavNbdWUmUblh1E8130_assertion description "[All four of the X-linked AI families (100%) had disease-causing mutations in AMELX, suggesting that AMELX is the only gene involved in the aetiology of X-linked AI.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489575.RAW7uYkK7FIeTeH1Bz8Tpma52lFf9KavNbdWUmUblh1E8130_provenance.
- NP489581.RAVmder5-7txJdWxcw7BNLiMrUxdShPHCP7TxedmSOAsE130_assertion description "[Antithrombin III, protein C, protein S, and the APC ratio, followed by a molecular genetic analysis, were measured, and molecular analysis of factor II G20210A mutation was used to detect the presence of an antithrombin III-, protein C- and protein S-deficiency, as well as factor V Leiden (factor V 506Arg to Gln) and factor II G20210A mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489581.RAVmder5-7txJdWxcw7BNLiMrUxdShPHCP7TxedmSOAsE130_provenance.
- NP489585.RAXxUWO0cCho2q-jQ6aSi8a_IfZRsY8Kx-alP-E4mNi6M130_assertion description "[Our aim was to investigate the function(s) of RACK1 and its involvement in mechanisms of breast carcinoma proliferation and invasion/metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489585.RAXxUWO0cCho2q-jQ6aSi8a_IfZRsY8Kx-alP-E4mNi6M130_provenance.
- NP489591.RARAffmGPPuhz5on-I4WYtVa2oIDVPsoQa3rOuW3wvvTc130_assertion description "[In order to investigate the mechanism of interferon-alpha (IFNalpha) action in the treatment of chronic myelogenous leukemia (CML), we examined surface expressions of both type I interferon receptor 1 (IFNAR1) and 2 (IFNAR2) subunits on CD34-positive cells in bone marrow (BM) in a total of 57 CML patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489591.RARAffmGPPuhz5on-I4WYtVa2oIDVPsoQa3rOuW3wvvTc130_provenance.
- NP489606.RASaObr7wvnJ2T2vsHCSrr48bWajz-dGUStPyDqTyqVDg130_assertion description "[In this study, we have applied 250K SNP array technology to detect previously cryptic chromosomal changes, particularly UPD, in a cohort of 301 patients with myelodysplastic syndromes (MDS), overlap MDS/myeloproliferative disorders (MPD), MPD, and acute myeloid leukemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489606.RASaObr7wvnJ2T2vsHCSrr48bWajz-dGUStPyDqTyqVDg130_provenance.
- NP489612.RAYx241SXqgfcblChYFbRuOCCX16a4mifv7NavVc-xAdY130_assertion description "[Overexpression of FOLR1 was observed in 11/16 (69%) of USC and 0/10 normal endometrium cases using frozen tissue specimens.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489612.RAYx241SXqgfcblChYFbRuOCCX16a4mifv7NavVc-xAdY130_provenance.
- NP489615.RAZGxHapt6Om3DBYj5RbZhV_Qc03YRJhVDRC7DTdxoni4130_assertion description "[The method was used to determine levels of three miRNA biomarkers of breast cancer (miRNA 21, 125b, 145) in a human breast cancer cell line (MCF-7).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489615.RAZGxHapt6Om3DBYj5RbZhV_Qc03YRJhVDRC7DTdxoni4130_provenance.
- NP489619.RAdhMC3mM_t6X0YweD_unvipqo2e9Jdt2dPkKm6vihlms130_assertion description "[Treatment with AL selected for the chloroquine-susceptible pfcrt K76 allele (P < .0001) and, to a lesser extent, the pfmdr1 N86 (P = .048) allele among recurrent infections.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489619.RAdhMC3mM_t6X0YweD_unvipqo2e9Jdt2dPkKm6vihlms130_provenance.
- NP489623.RAb1O2Yj3veeUkHeubHFvl4DfazvJUHfEud4gUNIytnII130_assertion description "[The mean age-matched value of BMD (Z scores) at the lumbar spine in patients with osteoporosis was significantly lower than that in patients with osteoarthrosis or healthy volunteers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489623.RAb1O2Yj3veeUkHeubHFvl4DfazvJUHfEud4gUNIytnII130_provenance.
- NP489633.RAfIRQNZcB_casF_bl7GzpOuuPYheg79vCIvqjdo5AZVk130_assertion description "[Mutations in NKX2.1, NKX2.5, FOXE1 and PAX8 genes, encoding for transcription factors involved in the development of the thyroid gland, have been identified in a minority of patients with syndromic and non-syndromic congenital hypothyroidism (CH).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489633.RAfIRQNZcB_casF_bl7GzpOuuPYheg79vCIvqjdo5AZVk130_provenance.
- NP489636.RASICgW3dRfqcavnHINDZZZbUb-1-oRj7QUWH4Rn7ksoA130_assertion description "[In this study, we evaluated the risk of acute graft-versus-host disease (GVHD) associated with genetic variation in recipient and donor MTHFR and TS genotypes to assess whether genotype alters the efficacy of MTX in acute GVHD prophylaxis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489636.RASICgW3dRfqcavnHINDZZZbUb-1-oRj7QUWH4Rn7ksoA130_provenance.
- NP489637.RAdk4tCIOE0mutVTC8LxydbjP4MBgjw-UhkU_oZiJyNVY130_assertion description "[There have been several conflicting reports of association of monoamine oxidase (MAO) A gene polymorphisms and bipolar affective disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489637.RAdk4tCIOE0mutVTC8LxydbjP4MBgjw-UhkU_oZiJyNVY130_provenance.
- NP489644.RAVvBmBc5VG5yEvy71XBhct_HUlu0_DGjITQdo68yotI4130_assertion description "[In a multivariable logistic regression analysis adjusted for traditional cardiovascular risk factors and chronic obstructive pulmonary disease, -1306C/T MMP2 (odds ratios [OR] = 0.55 [95% confidence interval, CI .34-.85], P < .007) and G1355A ELN (OR = 0.64 ([95% CI .41-.99], P = .046) polymorphisms resulted in independent protective factors for abdominal aortic aneurysm (AAA), whereas 5A/6A MMP3 (OR = 1.82 [95% CI 1.04-3.12], P = .034) and -77 A/G MMP-13 (OR = 2.14 [95% CI 1.18-3.86], P = .012) polymorphisms resulted in independent risk factors for AAA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489644.RAVvBmBc5VG5yEvy71XBhct_HUlu0_DGjITQdo68yotI4130_provenance.
- NP489647.RAa9aYGuU3_qHqZ-PkvEjMXpGnURTLOCmy1TvVnLYM1WA130_assertion description "[Intratumoral administration of adenoviruses expressing Flagrp170 induces a superior antitumor response against B16 melanoma and its distant lung metastasis compared with unmodified Grp170 and flagellin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489647.RAa9aYGuU3_qHqZ-PkvEjMXpGnURTLOCmy1TvVnLYM1WA130_provenance.
- NP489650.RAZokd6hRV00GBHX_eEFLfOVB2JdbjOybAbWfqDVMOZ3E130_assertion description "[Three hundred and eighty-nine and 261 consecutive BP-II and MDD patients, respectively, presenting for treatment of depression in an Italian private practice, were interviewed by a mood specialist psychiatrist using the Structured Clinical Interview for DSM-IV Axis I Disorders - Clinician Version as modified by the authors to improve the probing for hypomania.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489650.RAZokd6hRV00GBHX_eEFLfOVB2JdbjOybAbWfqDVMOZ3E130_provenance.
- NP489651.RAS_U3PhlgsQJQKSxSbHDD_isnHxYCLELuhDbk2JS-YrQ130_assertion description "[Previously, we analyzed 115 human post-mortem brain samples from the frontal lobe and reported DNA hypo methylation of the membrane-bound catechol-O-methyltransferase (MB-COMT) gene promoter, associated with an increased gene expression, as a risk factor for schizophrenia (SCZ) and bipolar disorder (BD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489651.RAS_U3PhlgsQJQKSxSbHDD_isnHxYCLELuhDbk2JS-YrQ130_provenance.
- NP489659.RATuUelGB62NTLo4ZKnHmUY-VvpG5WonhD43_R8Kxq_U0130_assertion description "[We also detected a relatively high incidence (12.3%) of c.871G > A, and all of them harbored the silent mutation c.1311C > T. Apart from the screening program, the pharmacogenetic relationship between G6PD level and residual reduced glutathione (GSH) level was studied upon oxidative challenge by alpha-naphthol.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489659.RATuUelGB62NTLo4ZKnHmUY-VvpG5WonhD43_R8Kxq_U0130_provenance.
- NP489660.RAYHNXBXfDWHI7skdDgHNWagIM_3MatEo8XX8bZhKhF1s130_assertion description "[These observations suggest that the NAT1*11 variant and the GSTM1 wild-type genotype contribute to a more favorable outcome in patients treated for neuroblastoma and are the first to demonstrate a relationship between NAT1 and GSTM1 genotypes in childhood neuroblastoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489660.RAYHNXBXfDWHI7skdDgHNWagIM_3MatEo8XX8bZhKhF1s130_provenance.
- NP489665.RAWa_seQrws7Cgfl9XOvTSC9kWPjAsQusOjSA1lprVNC8130_assertion description "[The transgenic astrocytomas exhibit additional molecular alterations associated with human astrocytomas, including a decreased or absent expression of p16, p19, and PTEN as well as overexpression of EGFR, MDM2, and CDK4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489665.RAWa_seQrws7Cgfl9XOvTSC9kWPjAsQusOjSA1lprVNC8130_provenance.
- NP489670.RAeZ-oPf4ewWI78LeIMRTgcsPsdSu3mw-x02f-cFoviME130_assertion description "[Conventional CGH revealed gains or amplifications of 12q13-q15 in six sarcomas and in two adrenocortical carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489670.RAeZ-oPf4ewWI78LeIMRTgcsPsdSu3mw-x02f-cFoviME130_provenance.
- NP489671.RAe2mmLQLNkBPq-bsIuIUfPhXLM2t53Fs6EWjMCE6Rko0130_assertion description "[In addition, we hypothesized WTIP gene haploinsufficiency as responsible for hypospadias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489671.RAe2mmLQLNkBPq-bsIuIUfPhXLM2t53Fs6EWjMCE6Rko0130_provenance.
- NP489672.RAao9LMG5T4udgiMIuEunLVSBIupA9gehBOojMajhtMus130_assertion description "[A secondary objective was to use the sperm chromatin dispersion test (SCD) to study antioxidant effects upon a specific subpopulation of highly DNA degraded sperm (DDS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489672.RAao9LMG5T4udgiMIuEunLVSBIupA9gehBOojMajhtMus130_provenance.
- NP489675.RAcMry7vpyF8_xCpk5jz3JIy39DKREZKhjRvHeZ4Mua5w130_assertion description "[All had been diagnosed as acute myeloid leukaemia (AML), 27 FAB subtype M2 and two M1, comprising 5% of all cytogenetically analysed AML during 18 yr. Auer rods were the most consistent t(8;21)-associated morphological finding and were demonstrated in 92% of the reviewed BM specimens, whereas BM eosinophilia was seen in only 24%.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489675.RAcMry7vpyF8_xCpk5jz3JIy39DKREZKhjRvHeZ4Mua5w130_provenance.
- NP489678.RAVpGNfAjPg1UU0Gt_lxBFnqyszuxHEAtWLTKnz3Y8wMc130_assertion description "[Both Raf/MEK/ERK and PI3K/Akt/mTOR pathways are over-expressed and/or over-activated in pituitary tumours: these pathways share a common root, including initial activation related to the tyrosine kinase receptor, and we speculate that a change to these receptors or their relationship to membrane matrix-related proteins may be an early event in pituitary tumourigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489678.RAVpGNfAjPg1UU0Gt_lxBFnqyszuxHEAtWLTKnz3Y8wMc130_provenance.
- NP489680.RAcQynJ7ZDHbX79Ut6P6k22ZRXF7o0lAUA2oX0YhIQED0130_assertion description "[To evaluate potential mechanisms of MMR regulation in arthritis, fibroblast-like synoviocytes (FLS) were isolated from synovial tissues and incubated with the NO donor S-nitroso-N-acetylpenicillamine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489680.RAcQynJ7ZDHbX79Ut6P6k22ZRXF7o0lAUA2oX0YhIQED0130_provenance.
- NP489684.RAcvoB5odnxcChgAn5BXIE6xRZ5kd7UiUkd_kyxlU5W2g130_assertion description "[The combined data for MTCs and pheochromocytomas suggest that the smallest region of overlap of LOH is bounded by D1S15 (1pter-p22) and D1Z2 (1P36.3), excluding a region around MYCL (1p32).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489684.RAcvoB5odnxcChgAn5BXIE6xRZ5kd7UiUkd_kyxlU5W2g130_provenance.
- NP489686.RAYRrPM05axlxFe8g9TKMRwGFKPM0mj5yX7ojVphdd7bE130_assertion description "[Among the various hereditary cancer syndromes, Hereditary non polyposis Colorectal Cancer (HNPCC or Lynch syndrome), Familial Adenomatous Polyposis (FAP) and related syndromes, Hereditary Breast tumours, Li-Fraumeni syndrome and Von Hippel-Lindau disease have been discussed in more detail.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489686.RAYRrPM05axlxFe8g9TKMRwGFKPM0mj5yX7ojVphdd7bE130_provenance.
- NP489688.RAclaCnI5Tjtw4mBJvCUmAAbeIoIuyEsvrc2WSjYe27y8130_assertion description "[We investigated the prevalence and the molecular characteristics of vancomycin-intermediate Staphylococcus aureus (VISA) among methicillin-resistant Staphylococcus aureus (MRSA) strains isolated from clinical samples at tertiary or general hospitals participating in a nationwide surveillance program for VISA and vancomycin-resistant Staphylococcus aureus (VRSA) in Korea during an 8-week period in each year from 2001 to 2006.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489688.RAclaCnI5Tjtw4mBJvCUmAAbeIoIuyEsvrc2WSjYe27y8130_provenance.
- NP489689.RAb_Ftj3dsit24oQUFcUY9JPZPCLrQH8rE7emkjCScQD0130_assertion description "[Epidermolysis bullosa with congenital pyloric atresia: novel mutations in the beta 4 integrin gene (ITGB4) and genotype/phenotype correlations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489689.RAb_Ftj3dsit24oQUFcUY9JPZPCLrQH8rE7emkjCScQD0130_provenance.
- NP489694.RAd3rQFoxsFJo-iBBExs1sjZMFGGxZdkFVr_kk8hiHbdQ130_assertion description "[Atypical chronic myeloid leukemia as defined in the WHO classification is a JAK2 V617F negative neoplasm.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489694.RAd3rQFoxsFJo-iBBExs1sjZMFGGxZdkFVr_kk8hiHbdQ130_provenance.
- NP489707.RAQShAjVjW3550xFzmvvZvH_rXK3MftggZk-noC3WFxKU130_assertion description "[Effectiveness of peripheral thyrotropin receptor mRNA in follow-up of differentiated thyroid cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489707.RAQShAjVjW3550xFzmvvZvH_rXK3MftggZk-noC3WFxKU130_provenance.
- NP489710.RAbudSJHGdNT4Q233J0SMODfUp-rYyYqI_hV82PokTY6M130_assertion description "[Despite significant similarities, HIF1 (HIF1α/ARNT) and HIF2 (HIF2α/ARNT) activate common as well as unique target genes and exhibit different functions in cancer biology.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489710.RAbudSJHGdNT4Q233J0SMODfUp-rYyYqI_hV82PokTY6M130_provenance.
- NP489713.RAaQ1D0R14DmF780pLBN5Uc3b-n47x1cBEdvUudTbaNNs130_assertion description "[To assess the relevance of MYCN amplification and bone lesions in stage 4 neuroblastoma (NB) in infants aged <1 year, 51 infants with stage 4 NB were enrolled.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489713.RAaQ1D0R14DmF780pLBN5Uc3b-n47x1cBEdvUudTbaNNs130_provenance.
- NP489714.RAQ_J8KDAA2-vaO3X52RvLNNdBWUbPXr0cYbIQ_VAUzcg130_assertion description "[Basal TNF-alpha mRNA expression was decreased in PBM from ACLD patients (-50.1+/-21.0%; P<0.05), with no significant differences in the other studied genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489714.RAQ_J8KDAA2-vaO3X52RvLNNdBWUbPXr0cYbIQ_VAUzcg130_provenance.
- NP489717.RAdPBGqmMLBohXAJ3lauYq_7_xrZUXILzItda1HZsb8ok130_assertion description "[Taken together, these results support SBSN as novel oncogene candidate in ACC, and the methylation changes could be a promising biomarker for ACC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489717.RAdPBGqmMLBohXAJ3lauYq_7_xrZUXILzItda1HZsb8ok130_provenance.
- NP489718.RAQW7RsWEZSVMtDpqAe2jJEHGCvHGztHixWKtTlyV_ooE130_assertion description "[Cytogenetic studies on a 17-year-old phenotypic male, with short stature and clinical and hormonal features of hypogonadism similar to those of an XX male, revealed an X;Y translocation, karyotype, 46,Xt(X;Y)(p22;?p11?q11).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489718.RAQW7RsWEZSVMtDpqAe2jJEHGCvHGztHixWKtTlyV_ooE130_provenance.
- NP489725.RAYouDn9ceZLrGG0B6tDSTto6TpK6dlTJUgwhRVV73NIA130_assertion description "[Genetic polymorphisms in folate pathway related enzymes including methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C, methionine synthase (MTR) A2756G, thymidylate synthase (TS) 28-bp tandem repeat, and reduced folate carrier (RFC) G80A have been shown to be associated with increased susceptibility for several cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489725.RAYouDn9ceZLrGG0B6tDSTto6TpK6dlTJUgwhRVV73NIA130_provenance.
- NP489726.RAbk4QkaWY9PuKDUgWns5hEnruD9BtJKVlnRfZaYTwf1M130_assertion description "[Although it shares many immunologic features with inflammatory bowel disease, celiac disease is uniquely characterized by (1) a defined trigger (gluten proteins from wheat and related cereals), (2) the necessary presence of HLA-DQ2 or HLA-DQ8, and (3) the generation of circulating autoantibodies to the enzyme tissue transglutaminase (TG2).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489726.RAbk4QkaWY9PuKDUgWns5hEnruD9BtJKVlnRfZaYTwf1M130_provenance.
- NP489729.RAe1MUVk3dcnLdiSfdSGbq4UgiSi9q0I0cghXCaLg7v3A130_assertion description "[Signaling mediated by the cytokine interleukin-7 is essential for the differentiation of T cells from lymphoid progenitors, and mutations of either the interleukin-7 receptor alpha chain (IL-7Ralpha) or its associated cytokine receptor chain, the common gamma chain (gammac), result in SCID.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489729.RAe1MUVk3dcnLdiSfdSGbq4UgiSi9q0I0cghXCaLg7v3A130_provenance.
- NP489731.RAfX6a-NhvYo9jJq5iex4c59s6wWsCC99Hu8oAIpE-jPQ130_assertion description "[Clonal analysis using X-chromosome inactivation patterns of the hypoxanthine phosphoribosyl transferase (HPRT) and phosphoglycerate kinase (PGK) genes has been used in the assessment of haematological malignancies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489731.RAfX6a-NhvYo9jJq5iex4c59s6wWsCC99Hu8oAIpE-jPQ130_provenance.
- NP489732.RAZlbL5ExR0jnlgrG453ehAFtCvBHAzl2f76XoUCLRSSM130_assertion description "[The data suggest that vitamin D3-repression of FAS mRNA expression is the consequence of feedback inhibition of FAS expression by long chain fatty acyl-CoAs, which are formed by FACL3 during its upregulation by vitamin D3 in human prostate cancer LNCaP cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489732.RAZlbL5ExR0jnlgrG453ehAFtCvBHAzl2f76XoUCLRSSM130_provenance.
- NP489743.RAQFX2ZDzNH18Q51H4qRM2nv7Zs8lek6NWyteGjiIoVaU130_assertion description "[RNAi-mediated suppression of FOXQ1 expression in highly invasive human breast cancer cells reversed EMT, reduced invasive ability, and alleviated other aggressive cancer phenotypes manifested in 3-dimensional Matrigel (BD Biosciences) culture.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489743.RAQFX2ZDzNH18Q51H4qRM2nv7Zs8lek6NWyteGjiIoVaU130_provenance.
- NP489759.RAekjU4-3MTRlo1UNY2k8ZQJ6fLIzYrPdKo2DearMN1xw130_assertion description "[The CD susceptibility gene has recently been identified as the PTEN/MMAC1/TEP1 gene localized at 10q23 and coding for a dual specificity protein phosphatase.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489759.RAekjU4-3MTRlo1UNY2k8ZQJ6fLIzYrPdKo2DearMN1xw130_provenance.
- NP489760.RAbixVeHY9YrvCxvtNtjTSQhoBsdrmvKmmnA2nHFMAT-A130_assertion description "[Therefore, SKY was used to characterize 37 cases of newly diagnosed AML-M2, previously analysed using G-banding.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489760.RAbixVeHY9YrvCxvtNtjTSQhoBsdrmvKmmnA2nHFMAT-A130_provenance.
- NP489762.RAYZCqXJVY64hjrDr7_hlUNa5EUzCTshVep_0Ro7wQWpE130_assertion description "[EMT transcription factors snail and slug directly contribute to cisplatin resistance in ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489762.RAYZCqXJVY64hjrDr7_hlUNa5EUzCTshVep_0Ro7wQWpE130_provenance.
- NP489769.RAeWOJOyjDrEr-b43_LjoZmoqzD_6_AEsS26B374w9U70130_assertion description "[URI is an `addicting` oncogene selectively required for the survival of ovarian cancer cells with increased URI copy number.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489769.RAeWOJOyjDrEr-b43_LjoZmoqzD_6_AEsS26B374w9U70130_provenance.
- NP489778.RARCJGPhxC-UOMz24dU5nyb1j4dnn25D7L_gwN2fUdbSY130_assertion description "[Among these are mutations in TNNC1- encoded cardiac troponin C, PLN-encoded phospholamban, and JPH2-encoded junctophilin 2 which have each been associated with HCM in multiple studies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP489778.RARCJGPhxC-UOMz24dU5nyb1j4dnn25D7L_gwN2fUdbSY130_provenance.