Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP490582.RAQU_N0qlBypW3BxqkDYuKyutFdz42OyiBfEA97p3KR-s130_assertion description "[Expressions of cytochrome P450, UDP-glucuronosyltranferase, and transporter genes in monolayer carcinoma cells change in subcutaneous tumors grown as xenografts in immunodeficient nude mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490582.RAQU_N0qlBypW3BxqkDYuKyutFdz42OyiBfEA97p3KR-s130_provenance.
- NP490585.RAQ2sgqo0MP-pA14ajW5ojtzvvBaGvj0hiqRtOV20wdlk130_assertion description "[The role of different DNA-repair genes (OGG1, XRCC1, XRCC2 and XRCC3) on both the spontaneous and the induced frequency of micronuclei (MN) has been studied in the lymphocytes of a group of 114 patients with differentiated thyroid cancer (DTC).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490585.RAQ2sgqo0MP-pA14ajW5ojtzvvBaGvj0hiqRtOV20wdlk130_provenance.
- NP490586.RAVitbNnQhMMXHazS7fRAEA_bKmPN9fa4visceF64f2XA130_assertion description "[Mutations involving the GRD region of the NF1 gene (GRD-NF1) have been described in a variety of tumors such as colon carcinoma and astrocytoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490586.RAVitbNnQhMMXHazS7fRAEA_bKmPN9fa4visceF64f2XA130_provenance.
- NP490592.RAdUh9ZbE-lhfmLQLQiaBMApgRFppPlcmAjfem6xVqkGM130_assertion description "[Screening for CFH-Ab and the CFHR1/CFHR3 deficiency should be included in the diagnostic tests for patients with aHUS.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490592.RAdUh9ZbE-lhfmLQLQiaBMApgRFppPlcmAjfem6xVqkGM130_provenance.
- NP490594.RAcZ0auLG8UvlMmLoerJT08_O4HK5cUbVNRmewGnSkfhg130_assertion description "[Cell adhesion may play a role in metastasis, and we have shown recently that expression of integrin alpha v beta 5 protein and mRNA is up-regulated in ganglioneuroblastomas in vivo.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490594.RAcZ0auLG8UvlMmLoerJT08_O4HK5cUbVNRmewGnSkfhg130_provenance.
- NP490595.RAe7OU_i3u3yL2Q13SUWlgXfXv7ui2ZV9FSHHnim0yezQ130_assertion description "[Host cells respond to viral infection through the activation of multiple signaling cascades, including the activation of NF-kappaB, c-Jun/ATF-2 (AP-1), and the interferon regulatory factors (IRFs).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490595.RAe7OU_i3u3yL2Q13SUWlgXfXv7ui2ZV9FSHHnim0yezQ130_provenance.
- NP490596.RAVDDgDVecY5L2I6580w__x9sW1xhL0bBUF-DB7pOjaYE130_assertion description "[Previous in vitro experiments demonstrated that Skp2, an E3 ubiquitin ligase aberrantly overexpressed in PCa, is involved in the proteolytic degradation of BRCA2 in PCa cells, suggesting that the BRCA2-Skp2 interaction may play a role in prostate tumorigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490596.RAVDDgDVecY5L2I6580w__x9sW1xhL0bBUF-DB7pOjaYE130_provenance.
- NP490600.RAd6mvsNPShfqWHYN4hY8CGtjrnOgQVK_8s13k-LWL9es130_assertion description "[We have investigated whether gallic acid (GA), an abundant red wine polyphenol, modulates the activity of P-selectin, an adhesion molecule that is critically involved in the recruitment of inflammatory cells to the vessel wall and thus in atherosclerosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490600.RAd6mvsNPShfqWHYN4hY8CGtjrnOgQVK_8s13k-LWL9es130_provenance.
- NP490605.RAR3GseuCxVGOXQ3ERAI3h9OAseKkL7ab0W-j4ZzXdqEY130_assertion description "[Our results showed positive statistical significant correlation between ZAP-70 expression and CD38 expression with some of the chromosomal aberrations encompassing bad prognosis as ATM and p53.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490605.RAR3GseuCxVGOXQ3ERAI3h9OAseKkL7ab0W-j4ZzXdqEY130_provenance.
- NP490607.RAQN34oEWhT1Bfkun9beP1geglnROVc8mTKLpgj73rBKM130_assertion description "[These findings show that excessive action of PQBP-1 causes neuronal dysfunction and support PQBP-1 being involved in the pathology of SCA1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490607.RAQN34oEWhT1Bfkun9beP1geglnROVc8mTKLpgj73rBKM130_provenance.
- NP490609.RAYQFRTsJ2b0YtKZ3U9rWiE7gxWbcfd3WJ21Ejv9d5_KA130_assertion description "[In this first phase of the project, the objective was to investigate the distribution of four candidate genetic polymorphisms for functional psychosis (Ser9Gly DRD3, 5HTTLPR, the VNTR 3'-UTR SLC6A3 and Val66Met BDNF) in a case-control sample.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490609.RAYQFRTsJ2b0YtKZ3U9rWiE7gxWbcfd3WJ21Ejv9d5_KA130_provenance.
- NP490610.RAQIaMrk3mCLlGo_kCeX1Y40Ezv5_cJDUziJS10trg4vk130_assertion description "[Of these four non-synonymous polymorphisms, the MTRR 1049GG variant was significantly associated with PD susceptibility (OR=3.17, 95%CI=1.08-9.35).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490610.RAQIaMrk3mCLlGo_kCeX1Y40Ezv5_cJDUziJS10trg4vk130_provenance.
- NP490611.RAVVGIowJ2SG1KJTTGVPdWpVpuF9GGzGUt7IilIapKHd8130_assertion description "[IRF4 is involved in the differentiation of B and T cells and is overexpressed in B-cell malignancies as a result of c-REL (NF-kappaB) hyperactivation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490611.RAVVGIowJ2SG1KJTTGVPdWpVpuF9GGzGUt7IilIapKHd8130_provenance.
- NP490615.RAUUUIH60u7euDiklWbtWNdf0yDldJg8zoA-Ni-fNi87Q130_assertion description "[Here we report that this process partially recapitulates embryonic endochondral bone formation in a spontaneous model of arthritis in DBA/1 mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490615.RAUUUIH60u7euDiklWbtWNdf0yDldJg8zoA-Ni-fNi87Q130_provenance.
- NP490633.RAXCD0atJKMXYlaC3Gac-8t0WktpDHits8fR5k9_Fhrxk130_assertion description "[Using immunocytochemistry, we explored the expression and cellular pattern of CBR 1 and 2 (CB1 and CB2) during prenatal human cortical development, as well as in focal malformations of cortical development associated with intractable epilepsy (focal cortical dysplasia; cortical tubers in patients with the tuberous sclerosis complex and glioneuronal tumors).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490633.RAXCD0atJKMXYlaC3Gac-8t0WktpDHits8fR5k9_Fhrxk130_provenance.
- NP490636.RARNiR6jCOZIaYDvsqB4fxA3aiUHxMlHs7FFIkGg764NQ130_assertion description "[Our results suggest that GJB2 and SLC26A4 mutations together make up a major cause of congenital hearing loss in the Korean population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490636.RARNiR6jCOZIaYDvsqB4fxA3aiUHxMlHs7FFIkGg764NQ130_provenance.
- NP490637.RAXCj5wJy79xfZ2W2RgwDk8rTxZWJe51F6heUm1_j1aoA130_assertion description "[Two types of single-point mutation in the cationic trypsinogen gene, which were identical with those reported in white families with hereditary pancreatitis, were observed in separate Japanese families with hereditary pancreatitis: 21Asn (AAC) to Ile (ATC) (N21I) in exon 2 and 117Arg (CGC) to His (CAC) (R117H) in exon 3.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490637.RAXCj5wJy79xfZ2W2RgwDk8rTxZWJe51F6heUm1_j1aoA130_provenance.
- NP490641.RAQcshEcOsYhNmgMvIReU61HjaSgIIrK5Sefg0l3CnXQg130_assertion description "[A large body of preclinical and clinical evidence points to a key role of the corticotropin-releasing hormone (CRH) receptor 1 subtype (CRHR1) in mediating CRH-elicited effects in anxiety, depressive disorders and stress-associated pathologies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490641.RAQcshEcOsYhNmgMvIReU61HjaSgIIrK5Sefg0l3CnXQg130_provenance.
- NP490643.RAUrsF-ive2uCZSn4VsLZ40U3Gq93XCOuIOW3O_WCV2Lw130_assertion description "[We identified SIRT2, which preferentially deacetylates tubulin and histone H4, as a downregulated protein in gliomas due to its epigenetic aberration.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490643.RAUrsF-ive2uCZSn4VsLZ40U3Gq93XCOuIOW3O_WCV2Lw130_provenance.
- NP490644.RAbP9hgTMniONI1I7UXylWKj_WwtcrFk81KPaQ2Ou_-GI130_assertion description "[Hb A2/E levels found in co-inheritance with the α-thalassemia-1 - -(SEA)/type deletion and either Hb E or β-thalassemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490644.RAbP9hgTMniONI1I7UXylWKj_WwtcrFk81KPaQ2Ou_-GI130_provenance.
- NP490647.RAWLLp-BsKw259VbR_i93VqB9idTdbw9hl3EL63x7hI9Q130_assertion description "[For three of these five genes [PGR (coding for the progesterone receptor), HSD17B4 (coding for type 4 17-beta-hydroxysteroid dehydrogenase, an enzyme that mainly degrades active 17-beta-estradiol into inactive metabolites), and CDH13 (coding for H-cadherin)] a higher prevalence of DNA methylation in HER-2/neu-positive cancers was confirmed in an independent set of microdissected primary breast cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490647.RAWLLp-BsKw259VbR_i93VqB9idTdbw9hl3EL63x7hI9Q130_provenance.
- NP490650.RAXrWbJOaWL0BuzSC4O_TGzWg7CAmhudNKoJxkee7jhlo130_assertion description "[Similarly, HCC risk associated with heavy alcohol intake and current smoking differed by this polymorphism among CLD patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490650.RAXrWbJOaWL0BuzSC4O_TGzWg7CAmhudNKoJxkee7jhlo130_provenance.
- NP490663.RAfzd9BC4i_UvX_AwvgyBiXarqNniYLj3rYbpywNZ0nWs130_assertion description "[We have determined that the human gene (PDEB) maps to 4p16.3, very close to the Huntington disease (HD) region.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490663.RAfzd9BC4i_UvX_AwvgyBiXarqNniYLj3rYbpywNZ0nWs130_provenance.
- NP490667.RAX_ZvzvL052DDqOWtFey5ETmE5kjCFx3408Y2-iw5Hok130_assertion description "[These findings suggest that the 5-HT1B polymorphism is unlikely to play a major role in the genetic susceptibility to suicide attempts.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490667.RAX_ZvzvL052DDqOWtFey5ETmE5kjCFx3408Y2-iw5Hok130_provenance.
- NP490669.RARdLxxHBevnp_EnMaKsIGafvJfYVZh9IUPQFyEjf4_cI130_assertion description "[CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490669.RARdLxxHBevnp_EnMaKsIGafvJfYVZh9IUPQFyEjf4_cI130_provenance.
- NP490672.RAXNOsVYpL4YNy9qzWOHWK9mgJL2yB7ur6_8pmYju9zYw130_assertion description "[Genome-wide association studies have revealed that the 16p13 chromosomal region, including CLEC16A, DEXI, CIITA and SOCS1, is associated with susceptibility to autoimmune diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490672.RAXNOsVYpL4YNy9qzWOHWK9mgJL2yB7ur6_8pmYju9zYw130_provenance.
- NP490673.RAX8mltLZmBiMtXQuIIUKQ7xp3KGgQj_1_aRJu26eN3Fo130_assertion description "[However, mutation exclusivity may indicate negative genetic interactions, as proposed herein for PBRM1 and BAP1, and mutations in these genes define RCC with different pathologic features, gene expression profiles, and outcomes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490673.RAX8mltLZmBiMtXQuIIUKQ7xp3KGgQj_1_aRJu26eN3Fo130_provenance.
- NP490675.RAbpMz_dnrFZ71xn3RBuAsWkCghXoCRboNC8F15QXzbE0130_assertion description "[In this study, we examined the specificity of benzene-induced aneuploidy and the influence of genetic polymorphisms (GSTM1, GSTT1, GSTP1, NAT2, NQO1 and CYP2E1) on chromosomal aberrations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490675.RAbpMz_dnrFZ71xn3RBuAsWkCghXoCRboNC8F15QXzbE0130_provenance.
- NP490679.RAW2eriuBcATXugMYXoziNz8XiPBAdAs4HPJ8fJBFGRqM130_assertion description "[P105 expression is absent in 58% of high grade NHL, particularly in centroblastic and Burkitt's lymphomas, suggesting that inactivation of RB may play a crucial role in the pathogenesis of high grade NHL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490679.RAW2eriuBcATXugMYXoziNz8XiPBAdAs4HPJ8fJBFGRqM130_provenance.
- NP490683.RAUfFGfuy-28FLMKANQY75A13XUpzwas-N8gNrHbaDahg130_assertion description "[For this, IL-23p19(-/-), IL-17RA(-/-) and IL-22(-/-) mice were intravaginally inoculated with Candida, and vaginal lavage fluids were evaluated for fungal burden, PMN infiltration, the presence of S100 alarmins and inflammatory cytokines and chemokines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490683.RAUfFGfuy-28FLMKANQY75A13XUpzwas-N8gNrHbaDahg130_provenance.
- NP490686.RAfA8bFgFfYek9s0SOKjUrYz3b29cm7uuh7NCeXM-rDY0130_assertion description "[We genotyped nine SNPs for which there was some prior evidence of an association with breast cancer: CASP8 D302H (rs1045485), IGFBP3 -202 C --> A (rs2854744), SOD2 V16A (rs1799725), TGFB1 L10P (rs1982073), ATM S49C (rs1800054), ADH1B 3' UTR A --> G (rs1042026), CDKN1A S31R (rs1801270), ICAM5 V301I (rs1056538) and NUMA1 A794G (rs3750913).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490686.RAfA8bFgFfYek9s0SOKjUrYz3b29cm7uuh7NCeXM-rDY0130_provenance.
- NP490688.RATrCoPcJVAgwppZeqb_ZUdw1eJ_tdBhYqr1fujf17Mqo130_assertion description "[At present, there is no case report of HHV8- primary effusion lymphoma (PEL) with t(9;14)(p13;q32) involving both PAX-5 and immunoglobulin heavy chain gene rearrangement, which is a rare translocation in B-cell non-Hodgkin's lymphoma, in an HIV- patient.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490688.RATrCoPcJVAgwppZeqb_ZUdw1eJ_tdBhYqr1fujf17Mqo130_provenance.
- NP490691.RATi1-x3p4zWIwB8WGAH9uaBKVbUWMr06ZhNuaMjPg0Fk130_assertion description "[The enhanced therapeutic efficacy elicited by AdVPTEN plus DDP was closely associated with additive induction of G1 phase arrest and apoptosis via substantially modulating cell-cycle regulation molecules and activating intrinsic apoptotic pathway through P53 restoration, and overlapping inhibition of tumor angiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490691.RATi1-x3p4zWIwB8WGAH9uaBKVbUWMr06ZhNuaMjPg0Fk130_provenance.
- NP490694.RAW6xjRAz7KNxxKBkx8TrNnw-qYeM4w-eiDi8Q1rP0no4130_assertion description "[The observations on stomatocytes, normal absorption and synthesis of cholesterol and bile acids, abnormal kinetics of apolipoprotein A-I, evidence of normal ACAT activity and abnormal esterification of non-cholesterol sterols are findings presented for the first time in LCAT deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490694.RAW6xjRAz7KNxxKBkx8TrNnw-qYeM4w-eiDi8Q1rP0no4130_provenance.
- NP490697.RAU0Xne6AONaI6aVqz6Z20Bnzl2JNA-0rk9TEQJP83vXQ130_assertion description "[Based on the cytogenetic analysis, Ewing's sarcoma is related closely with PNET as shown by MIC2-protein reactivity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490697.RAU0Xne6AONaI6aVqz6Z20Bnzl2JNA-0rk9TEQJP83vXQ130_provenance.
- NP490700.RAd_GcJPxvAzku_UQranxcXNMKvRrIPAxaRJm3FK5gzvU130_assertion description "[To further assess the potential impact of IRF-2 mutations in tumorigenesis, we screened fresh pancreatic tumor explants and identified 2 IRF-2 point mutations in the 2 alleles of IRF-2 from a single tumor specimen.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490700.RAd_GcJPxvAzku_UQranxcXNMKvRrIPAxaRJm3FK5gzvU130_provenance.
- NP490710.RASO4Kf2gzdM0ZJvoy9aWyBfxG9UMrIfmNdyg0Gd6tJUc130_assertion description "[Amplification of the AIB1 gene was observed in 4.8% of breast cancers and 7.4% of ovarian cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490710.RASO4Kf2gzdM0ZJvoy9aWyBfxG9UMrIfmNdyg0Gd6tJUc130_provenance.
- NP490720.RARAZaRNEQNTcwGiwU-gwswuAVqC_xaKaWR4FJvezwylc130_assertion description "[In this study, we examined the effectiveness of 4-1BBL-expressing tumor cell vaccine in combination with CTLA-4 blockade on rejection of murine prostate cancer RM-1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490720.RARAZaRNEQNTcwGiwU-gwswuAVqC_xaKaWR4FJvezwylc130_provenance.
- NP490722.RAavszHukdaWLfUpT5qBmA6N2npM7K9-gxsL0Xv4IaceQ130_assertion description "[CD68 and CD163 as prognostic factors for Korean patients with Hodgkin lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490722.RAavszHukdaWLfUpT5qBmA6N2npM7K9-gxsL0Xv4IaceQ130_provenance.
- NP490724.RAc_Ul743Oy_NAkVHS1MjpwHfrri0wigX2uKGY5EmMNs8130_assertion description "[Protective effect of DRB1 locus against type 2 diabetes mellitus in Mexican Mestizos.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490724.RAc_Ul743Oy_NAkVHS1MjpwHfrri0wigX2uKGY5EmMNs8130_provenance.
- NP490725.RAfRlHkuTQxquLitdRgmY8IfCTKyJt2wDtetCUJEjHnHA130_assertion description "[This study investigated whether Tg single nucleotide polymorphisms (SNPs) relate to GD development in a Taiwanese population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490725.RAfRlHkuTQxquLitdRgmY8IfCTKyJt2wDtetCUJEjHnHA130_provenance.
- NP490727.RAa2sFnR0dXMTJKpnzP7PdrDa9JXWp6IEArdU7YWenpkw130_assertion description "[In a lung metastasis model, EMAP II blocked outgrowth of Lewis lung carcinoma macrometastases; total surface metastases were diminished by 65%, and of the 35% metastases present, approximately 80% were inhibited with maximum diameter <2 mm (P < 0.002 vs. controls).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490727.RAa2sFnR0dXMTJKpnzP7PdrDa9JXWp6IEArdU7YWenpkw130_provenance.
- NP490729.RAdR6bbhCPB4hueQ_26-DMprJG4NFka8lgykqxRX5tqY4130_assertion description "[To our knowledge, this is the first report on the appearance of CMV-specific T cells in CSF samples from a patient with CMV meningoencephalitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490729.RAdR6bbhCPB4hueQ_26-DMprJG4NFka8lgykqxRX5tqY4130_provenance.
- NP490735.RAe-I_r-Sx_514X2zaYq0T62nnKixw6Snz3TZGXKguTrg130_assertion description "[We report here the most extensive analysis of alterations of PAX5 coding sequence in 117 adult BCP-ALL patients in the unique clinical protocol GRAALL-2003/GRAAPH-2003.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490735.RAe-I_r-Sx_514X2zaYq0T62nnKixw6Snz3TZGXKguTrg130_provenance.
- NP490738.RAegVseR7J7Jlfii6gfqWE0reCvQCHSZKOXXbBTBwgILk130_assertion description "[These results support a correlation between the level of haptoglobin and NMO.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490738.RAegVseR7J7Jlfii6gfqWE0reCvQCHSZKOXXbBTBwgILk130_provenance.
- NP490745.RAWLTHFZFOK4D3NC3yV-3ymTNe-KNEt04uIsKEalBeui4130_assertion description "[We screened the normolipidemic and hyperlipidemic apoE2 homozygotes for common variants in candidate genes involved in lipolysis-the APOA1-C3-A4 gene cluster, lipoprotein lipase, and hepatic lipase-and analyzed for associations with the expression of hyperlipidemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490745.RAWLTHFZFOK4D3NC3yV-3ymTNe-KNEt04uIsKEalBeui4130_provenance.
- NP490748.RASvjuWGnQL3qSOEW8tkk-vZWt0qMmIcPrXOge8y64UPo130_assertion description "[Accumulating evidence suggests that PPARgamma agonists such as the thiazolidinediones (TZDs) may prove to be useful anti-cancer agents exhibiting anti-proliferative and/or pro-apoptotic affects in a range of cancer cell types including melanoma, however, the mechanisms underlying this effect remain unclear.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490748.RASvjuWGnQL3qSOEW8tkk-vZWt0qMmIcPrXOge8y64UPo130_provenance.
- NP490751.RAdaS1eDmU7GD0cTgfbYs_f-SMlk94_VqscZJfR11S2Zo130_assertion description "[High levels of p53 protein expression do not correlate with p53 gene mutations in anaplastic large cell lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490751.RAdaS1eDmU7GD0cTgfbYs_f-SMlk94_VqscZJfR11S2Zo130_provenance.
- NP490760.RATRVjsBjrjwyfl7RpiI1EnbNTaCBQ_pPOkeN3usGllDw130_assertion description "[Combining our previous data together, our results indicate that ANXA2 excessive expression enhances the malignancy of cancers partially by remodeling the cell microstructures.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490760.RATRVjsBjrjwyfl7RpiI1EnbNTaCBQ_pPOkeN3usGllDw130_provenance.
- NP490761.RAWmzf3pupaYbYnyMyEy1yGTpcBMpzL8v6sbKE-hurFSM130_assertion description "[PICV P2 strain causes a mild febrile reaction in guinea pigs, while P18 causes severe disease with clinical and pathological features reminiscent of Lassa hemorrhagic fever in humans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490761.RAWmzf3pupaYbYnyMyEy1yGTpcBMpzL8v6sbKE-hurFSM130_provenance.
- NP490782.RAajRp1QLjOpVELLk80JQ3fA2x6UR3G0DPTjlizGCmC9k130_assertion description "[However, the remarkable success of imatinib mesylate in the treatment of CML relegated HHT to oblivion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490782.RAajRp1QLjOpVELLk80JQ3fA2x6UR3G0DPTjlizGCmC9k130_provenance.
- NP490783.RAQ89NnDfklLLwErYcDyamZgtPKGD4hXiyw8xssAy1OOs130_assertion description "[While genetic association and mRNA expression studies implicate the tryptophan hydroxylase isoform-1 gene (TPH1) in depression and suicidality, the TPH1 gene is 150-fold less expressed in mouse brain than TPH2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490783.RAQ89NnDfklLLwErYcDyamZgtPKGD4hXiyw8xssAy1OOs130_provenance.
- NP490786.RAcFeFINS-XmOnvcavzYgJB7j4hmijgk1L-Zf25CL-JJ0130_assertion description "[Taken together, our results demonstrate the roles of multiple microRNAs and p38 signaling in the progression of cancer and demonstrate the therapeutic potential of targeting the p38 MAPK pathway for reversing EMT in an advanced tumor phenotype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490786.RAcFeFINS-XmOnvcavzYgJB7j4hmijgk1L-Zf25CL-JJ0130_provenance.
- NP490791.RAeiSr1uQBdmEM3qrlnTPwXUY9MesOyzj7SATGkfhwiag130_assertion description "[To observe the effect of recombinant human epidermal growth factor (rhEGF) on ocular surface re-epithelization and the efficacy of amniotic membrane transplantation in patients with pterygium.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490791.RAeiSr1uQBdmEM3qrlnTPwXUY9MesOyzj7SATGkfhwiag130_provenance.
- NP490792.RAXpkJ0ctOLCBx1oFbelKyNcENQbyUIUK8D6ZwOAt9GhM130_assertion description "[Using polymerase chain reaction (PCR), we confirmed the expression of interleukin-1 alpha (IL-1 alpha) by the human nasopharyngeal carcinoma (NPC) cell line C15 without contribution of either human IL-1 beta or mouse IL-1 alpha in the biological activity previously found in C15.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490792.RAXpkJ0ctOLCBx1oFbelKyNcENQbyUIUK8D6ZwOAt9GhM130_provenance.
- NP490794.RAWjL97FSyZ8a4Ihg2ebXlQNbY5DE5MyFgZfSwP6mv9r0130_assertion description "[The mitogen-activated protein kinase kinase 1 and 2 signaling pathway is a major component of the RAS (Rat sarcoma)/RAF (Radpidly accelerated fibrosarcoma)/MEK (mitogen-activated protein kinase kinase)/ERKs (Extracellular signal-regulated kinases) signaling axis that regulates tumorigenesis and cancer cell growth.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490794.RAWjL97FSyZ8a4Ihg2ebXlQNbY5DE5MyFgZfSwP6mv9r0130_provenance.
- NP490795.RAfXHRsEduHRfXjtT-_qadHIRw3FQRFv46_Qo1cOQYLxQ130_assertion description "[Taken together, our findings are suggestive for a possible tumor suppressor role of DOK1 in EOC; however its implication in enhanced EOC cell migration and proliferation restrain us to conclude that DOK1 represents a true TSG in EOC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490795.RAfXHRsEduHRfXjtT-_qadHIRw3FQRFv46_Qo1cOQYLxQ130_provenance.
- NP490797.RAdJxSSnnQdcOxhL1JzN7Q18mMRMhVr6GHS210o0hgY_E130_assertion description "[Molecular cloning of a cell cycle regulation gene cyclin H from ischemic rat brain: expression in neurons after global cerebral ischemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490797.RAdJxSSnnQdcOxhL1JzN7Q18mMRMhVr6GHS210o0hgY_E130_provenance.
- NP490801.RAaPlwWfIEPuOF3RaMerCmFDUUXP3XBGFnMWBcHc6ZG8A130_assertion description "[The lysosomal cysteine protease cathepsin B has been implicated in tumor progression and metastasis in part due to its altered trafficking.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490801.RAaPlwWfIEPuOF3RaMerCmFDUUXP3XBGFnMWBcHc6ZG8A130_provenance.
- NP490802.RAXuPBTbUlVUzoP4zTyZ1xHcTooyT0M2v1HKbROGSho1c130_assertion description "[Our results demonstrate that the IL2/IL21 region, C8orf13-BLK, and CD226 influence RA in Colombians, and RA shares some of the pathogenic mechanisms associated with other autoimmune diseases.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490802.RAXuPBTbUlVUzoP4zTyZ1xHcTooyT0M2v1HKbROGSho1c130_provenance.
- NP490804.RAf1Bs-Ubx1WNTtGBuvKtOFaSId6_u6oo26fSJFt68IpY130_assertion description "[Taken together, we firstly demonstrated that the promoter methylation of MKP-1 gene is a potential breast cancer biomarker for breast malignancy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490804.RAf1Bs-Ubx1WNTtGBuvKtOFaSId6_u6oo26fSJFt68IpY130_provenance.
- NP490805.RAfCVcl6gAfsUVz2lDEKQS4vYy8D2DkP4E19uwq_syEXY130_assertion description "[Compared to younger adults, there was a 50% downregulation of CPT1 in elderly persons and in MDS patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490805.RAfCVcl6gAfsUVz2lDEKQS4vYy8D2DkP4E19uwq_syEXY130_provenance.
- NP490807.RAZU3SBXgac-xbV3B4EPMQFWJ4J2e7tNAZW3bCaC2qhic130_assertion description "[These data indicate that bile acid-mediated down-regulation of Cav1 marks early changes in the squamous epithelium, which may contribute to onset of Barrett esophagus metaplasia and progression to BAC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490807.RAZU3SBXgac-xbV3B4EPMQFWJ4J2e7tNAZW3bCaC2qhic130_provenance.
- NP490813.RAf8Rrtddbv1BhvWDpjuBjSPLWQ3pcVp8jG69ZqpStnyg130_assertion description "[Cleidocranial dysplasia (CCD), which is caused by mutations of the core binding factor alpha 1 (CBFA1)/runt-related gene 2 (Runx2), is an autosomal, dominantly inherited disorder of high penetrance affecting skeletal ossification and tooth development.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490813.RAf8Rrtddbv1BhvWDpjuBjSPLWQ3pcVp8jG69ZqpStnyg130_provenance.
- NP490816.RAU4CN0Ahz1SeqgZ_AGrpnNM6OCCf6YlIycQArQK_ig2I130_assertion description "[Recently, it has been reported that colorectal carcinoma is created and propagated by a small number of undifferentiated tumorigenic CD133(+) cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490816.RAU4CN0Ahz1SeqgZ_AGrpnNM6OCCf6YlIycQArQK_ig2I130_provenance.
- NP490822.RAUonKDFDqrrtXGaW6CQUZE-RFq3GlAHMjWl4P7C8XDbc130_assertion description "[Strategies aiming at targeting cancer stem cell metabolic adaptative responses, such as that through LRP differential expression within the brain tissue microenvironmental niche, can now be envisioned.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490822.RAUonKDFDqrrtXGaW6CQUZE-RFq3GlAHMjWl4P7C8XDbc130_provenance.
- NP490824.RAW9ymFbekqVZosjeW-fpB-BSQo_cToZTOGOgCbDqKCFI130_assertion description "[Interleukin-2 gene therapy of chronic neuropathic pain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490824.RAW9ymFbekqVZosjeW-fpB-BSQo_cToZTOGOgCbDqKCFI130_provenance.
- NP490835.RAWnXqphWnoxyx6iot6N7sVQ6R7RqB8nl8e5vPbVsvNLs130_assertion description "[We reexamined these findings as well as the role of another inflammatory bowel disease (IBD) susceptibility gene (immunity-related GTPase family, M [IRGM]) on transplantation outcomes in 390 US patients and their matched unrelated donors, accrued between 1995 and 2004.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490835.RAWnXqphWnoxyx6iot6N7sVQ6R7RqB8nl8e5vPbVsvNLs130_provenance.
- NP490837.RAUbv-uJdH3vMV2eM02kfVlZsb7YCyrGu6u9yR3OxyaGI130_assertion description "[Associations of ABCB1 and IL-10 genetic polymorphisms with sirolimus-induced dyslipidemia in renal transplant recipients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490837.RAUbv-uJdH3vMV2eM02kfVlZsb7YCyrGu6u9yR3OxyaGI130_provenance.
- NP490849.RAWCil1QEGJ_MV7iCuc7VAWnUOlCerbnKRfwrzh_OiVtY130_assertion description "[A connection between MEFV gene mutations and rheumatic diseases has been suggested.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490849.RAWCil1QEGJ_MV7iCuc7VAWnUOlCerbnKRfwrzh_OiVtY130_provenance.
- NP490854.RASqaMgVdwugxoVu1ENyCl9bwqlSzwzymkBKK8MZbF2ww130_assertion description "[A phase I dose escalation clinical trial of the intralesional administration of Ad-OC-hsv-TK followed by oral valacyclovir was conducted at the University of Virginia (Charlottesville, VA) in 11 men with localized recurrent and metastatic hormone-refractory prostate cancer (2 local recurrent, 5 osseous metastasis, and 4 lymph node metastasis) in order to determine the usefulness of this vector for the palliation of androgen-independent prostate cancer metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490854.RASqaMgVdwugxoVu1ENyCl9bwqlSzwzymkBKK8MZbF2ww130_provenance.
- NP490859.RAQ5NtaQNgP8b7C8Q8But6Ohy53xnZtQpQQWx7keu9JT0130_assertion description "[DNA samples from 20 patients with EA (with or without interictal nystagmus) negative for CACNA1A mutations were analyzed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490859.RAQ5NtaQNgP8b7C8Q8But6Ohy53xnZtQpQQWx7keu9JT0130_provenance.
- NP490861.RAVXfb2jLSZbmBEHj3FvBpaQIUaTb94u30eDswklrykYo130_assertion description "[The present studies tested how TD alters brain pathology in Tg19959 transgenic mice over expressing a double mutant form of the amyloid precursor protein (APP).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490861.RAVXfb2jLSZbmBEHj3FvBpaQIUaTb94u30eDswklrykYo130_provenance.
- NP490864.RAU3Pvpa9QeZVBk4TtfJNb48BZSMHV7hqwzlvR4JiyNTM130_assertion description "[Expression of p110 and p75 CUX1 in transgenic mice increases the susceptibility to cancer in various organs and tissues.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490864.RAU3Pvpa9QeZVBk4TtfJNb48BZSMHV7hqwzlvR4JiyNTM130_provenance.
- NP490867.RAe2JcAPoJTkGx3D5XwlfuZkrxlu2jyGB7yq561F5QCn8130_assertion description "[We conclude that the patient harbored two distinct lymphoproliferative disorders, a TRAP+, Tac+ B cell malignancy consistent with hairy cell leukemia that did not contain HTLV-II and a Tac-, CD8+ lymphoproliferative syndrome with oligoclonally integrated HTLV-II.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490867.RAe2JcAPoJTkGx3D5XwlfuZkrxlu2jyGB7yq561F5QCn8130_provenance.
- NP490868.RASSecIYHj6919Lg5pGTTBaQN-MnNMe2Fd8cD_0hZOPyg130_assertion description "[We found that HDACIs Trichostatin A (TSA) and Suberoylanilide hydroxamic acid (SAHA) could induce epithelial-to-mesenchymal transition (EMT) phenotype in prostate cancer (PCa) cells, which was associated with changes in cellular morphology consistent with increased expression of transcription factors ZEB1, ZEB2 and Slug, and mesenchymal markers such as vimentin, N-cadherin and Fibronectin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490868.RASSecIYHj6919Lg5pGTTBaQN-MnNMe2Fd8cD_0hZOPyg130_provenance.
- NP490873.RAVOfFmu3giYPgN-0YjeNXmA_0xL-2r_Ha1k_GdjCHpdU130_assertion description "[These studies suggest that the expression and activation of CCR9 affect cancer cell migration, invasion, and MMP expression, which together may affect prostate cancer metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490873.RAVOfFmu3giYPgN-0YjeNXmA_0xL-2r_Ha1k_GdjCHpdU130_provenance.
- NP490879.RAd52-0kkIlqZPYvGo65_IwVDOk7kBWBcp38NPJlHkRfQ130_assertion description "[Loss of imprinting (LOI) at both H19 and IGF2 has been reported in seven fully informative adult testicular germ cell tumors (GCTs) and may contribute to germ cell carcinogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490879.RAd52-0kkIlqZPYvGo65_IwVDOk7kBWBcp38NPJlHkRfQ130_provenance.
- NP490891.RAeacglSrLx04HNb9yirV-Hi72amYKJDyynv3OJXukAk0130_assertion description "[A previous whole-genome scan (WGS) of 182 UK rheumatoid arthritis (RA) affected sibling pair (ASP) families suggested linkage to HLA and 11 other chromosome regions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490891.RAeacglSrLx04HNb9yirV-Hi72amYKJDyynv3OJXukAk0130_provenance.
- NP490900.RATh0m4cdiuUecRIBY9_GpWV7QGcIc-TYxqiwU3Nk0FWU130_assertion description "[However, activation of the RAS-RAF-MEK-ERK MAPK pathway is commonly observed in human breast cancers, suggesting that other genetic alterations lead to activation of this signaling pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490900.RATh0m4cdiuUecRIBY9_GpWV7QGcIc-TYxqiwU3Nk0FWU130_provenance.
- NP490904.RAe-SJE2g62r3Y2QCfcGhW1VglyUidzVrCWV3QCgC5BNk130_assertion description "[The authors used CGH to examine 40 primary and 13 recurrent adenomas obtained from 52 patients for loss and gain of genetic material.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490904.RAe-SJE2g62r3Y2QCfcGhW1VglyUidzVrCWV3QCgC5BNk130_provenance.
- NP490906.RAdvtg86Tc0FfPL5b47IP90EFIvzCXZZqdJDLEgHqzDk8130_assertion description "[Finally, Myc/TTP-directed control of select cancer-associated ARED genes is disabled during lymphomagenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490906.RAdvtg86Tc0FfPL5b47IP90EFIvzCXZZqdJDLEgHqzDk8130_provenance.
- NP490910.RAbnmV5_xjCH06qicFjoyVIjmFHf-talTSq0m0EaMxzbg130_assertion description "[We used human microvascular endothelial cells (HMEC-1) transfected with a DNAzyme targeting the c-Jun mRNA (Dz13), related oligonucleotides, or vehicle in in vitro models of microvascular endothelial cell proliferation, migration, chemoinvasion, and tubule formation, a rat model of corneal neovascularization, and a mouse model of solid tumor growth and vascular endothelial growth factor (VEGF)-induced angiogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490910.RAbnmV5_xjCH06qicFjoyVIjmFHf-talTSq0m0EaMxzbg130_provenance.
- NP490911.RAeVTvIt2U3XzAPJjuCeEryzM2WFbKV9tZWuWzjwjN5aU130_assertion description "[Neuronal nitric oxide synthase (nNOS) mRNA levels and NADPH diaphorase (NADPH-d) staining were compared in the frontal cortex, visual cortex and hippocampus (dentate gyrus and CA subfields of Ammon's horn) of five Alzheimer's disease (AD) and six control brains.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490911.RAeVTvIt2U3XzAPJjuCeEryzM2WFbKV9tZWuWzjwjN5aU130_provenance.
- NP490914.RAZKLc-21t1KXqmaIdQnwxpVeHdJyhORP6iw130jqfSdY130_assertion description "[In the present study, we used quantitative methylation-specific PCR (Q-MSP) assays to analyze promoter hypermethylation of nine genes in a large cohort of well-characterized non-small cell lung cancer (NSCLC) and explore their associations with the clinicopathological features of tumor.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490914.RAZKLc-21t1KXqmaIdQnwxpVeHdJyhORP6iw130jqfSdY130_provenance.
- NP490915.RAWp360dbfZMoqM_pHmkpjCN6KYDC2bxtUfTjW8LTmvYw130_assertion description "[General linear models (GLM) were fit to examine the relation of waist circumference (WC) to insulin resistance and metabolic risk scores.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490915.RAWp360dbfZMoqM_pHmkpjCN6KYDC2bxtUfTjW8LTmvYw130_provenance.
- NP490918.RAbHVh3Isf-tDo28Nyc-3Ol2bazal6fzSXGZQDTW2anNA130_assertion description "[The GSTM1 and GSTT1 genotypes did not seem to modify the association between cruciferous vegetable intake and colorectal adenomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490918.RAbHVh3Isf-tDo28Nyc-3Ol2bazal6fzSXGZQDTW2anNA130_provenance.
- NP490926.RAdHvh9bpgDxhjwDX3UmeEfbBK8KSit59q6RngFkINTvM130_assertion description "[In light of the reported functional involvement of the KLF6 gene in lung cancer and in other cancer types and to the functional nature of the rs3750861 SNP, our results suggest a potential involvement of KLF6 polymorphisms in lung cancer risk, although additional studies in large series are needed to confirm our findings and to elucidate the mechanism by which the KLF6 SNPs influence lung cancer risk.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490926.RAdHvh9bpgDxhjwDX3UmeEfbBK8KSit59q6RngFkINTvM130_provenance.
- NP490935.RAc781Qtg-QyDVtW98goCXI1XjeOP_q4l3FC4Ytzdj1os130_assertion description "[This patient's intermediate-risk HPV infection (HPV-83) rapidly progressed to severe cervical intraepithelial neoplasia (CIN III) with strong anti-P16(INK4a) immunolabelling.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490935.RAc781Qtg-QyDVtW98goCXI1XjeOP_q4l3FC4Ytzdj1os130_provenance.
- NP490942.RASZmkScefINAFQ4htYMBo5LuN85c7-owb09CjzKQSDpM130_assertion description "[This paper introduces triplex PCR-CTPP to simultaneously genotype three functional polymorphisms of carcinogen-detoxifying enzymes, NQO1 C609T, GSTM1 null, and GSTT1 null, all of which are reported to have a significant association with smoking-related cancers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490942.RASZmkScefINAFQ4htYMBo5LuN85c7-owb09CjzKQSDpM130_provenance.
- NP490943.RATXKl46NGWe8ob3omzqbNcgwYYc_OQE0KMFR-HwxSrqA130_assertion description "[A deletion of Asn169 in the peripherin/RDS protein causes a peculiar form of autosomal dominant macular dystrophy in a large family from the Netherlands.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490943.RATXKl46NGWe8ob3omzqbNcgwYYc_OQE0KMFR-HwxSrqA130_provenance.
- NP490948.RAYUY9UmsqVqppJ1tx40vUT8znmmj74lQ8P7SiZXZpu8s130_assertion description "[However, the role of MAPK kinases (MAPKKs or MEKs) in cancer is unclear, although constitutively activated MEK1, which does not exist in nature, is `oncogenic.` Herein, we found that T-cell-originated protein kinase (TOPK), a member of the MAPKK protein family, is highly expressed in human colorectal cancer tissues and cell lines and plays an important role in the transformation of colorectal cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490948.RAYUY9UmsqVqppJ1tx40vUT8znmmj74lQ8P7SiZXZpu8s130_provenance.
- NP490954.RASrV77SKQznp-ZU_KPck-RBAuR9rFIiw042C-RnGCGJs130_assertion description "[HT1080 fibrosarcoma and C32 melanoma cells utilize GPIV in concert with a heparin-modulated binding systems to attach and spread on TSP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490954.RASrV77SKQznp-ZU_KPck-RBAuR9rFIiw042C-RnGCGJs130_provenance.
- NP490959.RARXJDGgjDB4kxmckKjyw4WO-PdRsw_v0Xvbxs5M0G5HQ130_assertion description "[The goal of the study reported here was to assess the role of the INSIG2 single nucleotide polymorphism (SNP) in susceptibility to obesity in the prospective longitudinal Atherosclerosis Risk in Communities (ARIC) study (n = 14,566) and in three other cohorts: the Coronary Artery Risk Development in Young Adults (CARDIA) study (n = 3,888), the Genetic Epidemiology Network of Arteriopathy (GENOA) study (n = 4,766), and extremely obese and lean individuals ascertained at the University of Ottawa (n = 1,502).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490959.RARXJDGgjDB4kxmckKjyw4WO-PdRsw_v0Xvbxs5M0G5HQ130_provenance.
- NP490961.RAbO0zXpA8GoMsFGB4UidiciWBeVCeAZYOBP_ia3T59nk130_assertion description "[Congenital acute monoblastic leukemia with double translocation (8;16) (p11;p13) and (16;20) (q13;p13).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490961.RAbO0zXpA8GoMsFGB4UidiciWBeVCeAZYOBP_ia3T59nk130_provenance.
- NP490962.RAXEMxSPF-oKjlh3yVR2n0RDhA46Fz4a1GOrl4QTQ6AfI130_assertion description "[Our results support a role for HLA in the etiology of NHL and its subtypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490962.RAXEMxSPF-oKjlh3yVR2n0RDhA46Fz4a1GOrl4QTQ6AfI130_provenance.
- NP490970.RAbWKvnj7txkTrxaD3RXytVKjJKmWfq5HnHIpyyr6udQc130_assertion description "[The clinical, pathological, and radiological features are similar to the phenotype associated with fetal exposure to angiotensin converting enzyme (ACE) inhibitors: intrauterine growth retardation, skull ossification defects, and fetal/ neonatal anuric renal failure associated with renal tubular dysplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490970.RAbWKvnj7txkTrxaD3RXytVKjJKmWfq5HnHIpyyr6udQc130_provenance.
- NP490978.RAfviRFlVzTDQlMn4eb74E52QZ1rn_XB_rMMzjWJBti6E130_assertion description "[We evaluated 107 subfertile patients, male partners of infertile couples, affected by non-obstructive azoospermia (n = 38) and oligoasthenoteratozoospermia (OAT) (n = 69), and 102 men with proven fertility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490978.RAfviRFlVzTDQlMn4eb74E52QZ1rn_XB_rMMzjWJBti6E130_provenance.
- NP490981.RAVOREibtHMDEvz_h_6lvckyyTLnM1zvngL5D4QOIrMeM130_assertion description "[Numerous genes were identified as being differentially expressed, some of which have been previously implicated in pancreatic adenocarcinoma (S100P, S100A4, prostate stem cell antigen, lipocalin 2, claudins 3 and 4, trefoil factors 1 and 2) as well as several novel genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490981.RAVOREibtHMDEvz_h_6lvckyyTLnM1zvngL5D4QOIrMeM130_provenance.
- NP490982.RAYFiQn2qcq8jE2pGNQ-Td8FsURs4prYLS6uqMT6Vvm8A130_assertion description "[Since the beginning of our PGD activity, we have had 43 PGD referrals for HD, of which 24 were from patients who know their genetic status and 19 from patients who do not wish to perform PT.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP490982.RAYFiQn2qcq8jE2pGNQ-Td8FsURs4prYLS6uqMT6Vvm8A130_provenance.