Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP498164.RAaySTUdFMqzaI73rrvIPKsdjeXrTyyhSddc8QAU2WE3c130_assertion description "[c-Jun/AP-1 has been linked to invasive properties of aggressive breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498164.RAaySTUdFMqzaI73rrvIPKsdjeXrTyyhSddc8QAU2WE3c130_provenance.
- NP498169.RAfQish4_8xlVLPcvRn5-DKGW_5-WNyFrGxCRu2_dcVnI130_assertion description "[The present review summarizes the effects of both acute and chronic exposure to various drugs of abuse on individual PKC isozymes in the brain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498169.RAfQish4_8xlVLPcvRn5-DKGW_5-WNyFrGxCRu2_dcVnI130_provenance.
- NP498180.RAXCyjnNmRwQHu26EbNI6mrPNBJobYnasm0UCEb1wMg4g130_assertion description "[The average MIB-1 proliferation indices were 1.2% for primary and 1.9% for recurrent adenomas (P < 0.005).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498180.RAXCyjnNmRwQHu26EbNI6mrPNBJobYnasm0UCEb1wMg4g130_provenance.
- NP498182.RAQEBAbmn90V6MTSzy9rWOTrZJVHdPfENUo6TOf4aRVAM130_assertion description "[Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498182.RAQEBAbmn90V6MTSzy9rWOTrZJVHdPfENUo6TOf4aRVAM130_provenance.
- NP498187.RAU3NAv-0HaR0RWLvAEXIwcgCoEuqzVw6dFlRp9ZHvKWA130_assertion description "[Mutations in other genes, including ATP13A2 (PARK9), PLA2G6 (PARK14), and FBX07 (PARK15), cause more rare forms of recessive parkinsonism with very early-onset (<30 years) and usually additional, atypical features (pyramidal, dystonic, ocular movement, and cognitive disturbances).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498187.RAU3NAv-0HaR0RWLvAEXIwcgCoEuqzVw6dFlRp9ZHvKWA130_provenance.
- NP498188.RAWRn5M537_PgQSjJ7VPim6xEeFFF6hxj912oLcIh82gg130_assertion description "[The so-called pituitary tumour transforming gene (PTTG) encodes a 23 kDa, 202 amino acid protein, and is located on chromosome 5q33, a locus previously associated with recurrent lung cancer and acute myelogenous leukaemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498188.RAWRn5M537_PgQSjJ7VPim6xEeFFF6hxj912oLcIh82gg130_provenance.
- NP498189.RAZwdfij4sIXLPBCSN-zt525nNF50g_Hy0punrHY1m02w130_assertion description "[To analyze the role of the two primary open angle glaucoma (POAG) genes, myocilin (MYOC) and optineurin (OPTN), in a large Philippine family segregating autosomal dominant juvenile onset open angle glaucoma (JOAG).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498189.RAZwdfij4sIXLPBCSN-zt525nNF50g_Hy0punrHY1m02w130_provenance.
- NP498190.RAcXiqI5dGBy6VdElxNuvBYr4twUGnQkKiAb_CzbvhonE130_assertion description "[In two β-lactamase-positive isolates without PBP3 mutations, the inhibitor-resistant TEM (IRT) β-lactamases TEM-34 and the novel TEM-182 were detected and carried by a TnA transposon of the Tn2 type; both isolates had an amoxicillin/clavulanic acid MIC of ≥8 mg/L.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498190.RAcXiqI5dGBy6VdElxNuvBYr4twUGnQkKiAb_CzbvhonE130_provenance.
- NP498191.RARrYXsMB-BlNzFEroZbwCilaE1i0afk3i0fhcn7Lt21k130_assertion description "[Peak 11-deoxycortisol responses to LDT were significantly (p < 0.05) higher in NCAH patients (15.7 +/- 1.8 nmol/L) than in the control subjects (6.5 +/- 0.8 nmol/L).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498191.RARrYXsMB-BlNzFEroZbwCilaE1i0afk3i0fhcn7Lt21k130_provenance.
- NP498195.RAdGyLjA88n98SgQdJ_FwgSZXBW97qllWyZA1pxtJXYoU130_assertion description "[Role of p97 AAA-ATPase in the retrotranslocation of the cholera toxin A1 chain, a non-ubiquitinated substrate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498195.RAdGyLjA88n98SgQdJ_FwgSZXBW97qllWyZA1pxtJXYoU130_provenance.
- NP498202.RAWGVek0rYAje7aZH9eGBrgcjJQxR6XtqlEc4r54r33wY130_assertion description "[In response to hematopoietic growth factors RA-derived CD34(+) HPC expanded significantly less than age-matched controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498202.RAWGVek0rYAje7aZH9eGBrgcjJQxR6XtqlEc4r54r33wY130_provenance.
- NP498204.RAS5MZBvjkqy3uQUCcotbbIufTOXClrHwMQT6-11HTxp0130_assertion description "[AMPK has emerged as a critical mechanism for salutary effects of polyphenols on lipid metabolic disorders in type 1 and type 2 diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498204.RAS5MZBvjkqy3uQUCcotbbIufTOXClrHwMQT6-11HTxp0130_provenance.
- NP498209.RAVVTK3K2lwR1TaiZkY8DwR56Pnw4r6M5nREJlLRxOs5U130_assertion description "[Reflecting its role in reverse cholesterol transport, the CETP gene is up-regulated in peripheral tissues and liver in responses to dietary or endogenous hypercholesterolemia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498209.RAVVTK3K2lwR1TaiZkY8DwR56Pnw4r6M5nREJlLRxOs5U130_provenance.
- NP498223.RAXtm6bXCkf0A_aMGc-lm3FhPPEqHFT8vscK6yvdNuf3w130_assertion description "[In a single-center, population-based prospective study, allelic imbalance in chromosomes 1p36, 19q13, 17p13, 10p12-15, and 10q22-26 has been investigated in 19 oligodendroglioma WHO grade 2 (OII), 20 oligoastrocytoma WHO grade 2 (OAII), 8 oligodendroglioma WHO grade 3 (OIII), and 12 oligoastrocytoma WHO grade 3 (OAIII), and compared with pretherapy histopathology, computed tomography and/or magnetic resonance (CT and/or MR), [fluorine-18]fluoro-2-deoxyglucose (18F-FDG), and thallium-201 single-photon emission computed tomography (201Tl SPECT).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498223.RAXtm6bXCkf0A_aMGc-lm3FhPPEqHFT8vscK6yvdNuf3w130_provenance.
- NP498231.RAeDrSxOzgIWBG4GMpfhqS6PsuX8XPko8K2Z1WhiyboSw130_assertion description "[Interestingly, several genes (TESK2, TIPARP, THEMIS, ABLIM1, RFX4, STON2 and LILRA1) are associated with three personality traits with p < 10(-3) using single trait analysis and AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498231.RAeDrSxOzgIWBG4GMpfhqS6PsuX8XPko8K2Z1WhiyboSw130_provenance.
- NP498240.RAYmignS7bVUchLRiC3AxQfyvAK-umfE9V-3pn9Jr6vts130_assertion description "[The -374T/A RAGE promotor single nucleotide polymorphism (SNP) was negatively associated with CD (odds ratio = 0.708, 95% confidence interval = 0.535-0.938, P = 0.016) and with stenosis (OR = 0.627, P = 0.04) in the German sample.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498240.RAYmignS7bVUchLRiC3AxQfyvAK-umfE9V-3pn9Jr6vts130_provenance.
- NP498247.RAVbfWJhzxW89XRtd50TRUViA9H6byXvOo2jgD5LCa-v4130_assertion description "[The results obtained with the study of HLA-DRB1 locus in patients affected by OA and living in Liguria may suggest a research on a larger number of OA patients to confirm the data obtained in this study and to define DRB1 haplotypes as more frequent markers both in OA of the hand and in OA of other joints.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498247.RAVbfWJhzxW89XRtd50TRUViA9H6byXvOo2jgD5LCa-v4130_provenance.
- NP498253.RATluamM7Onpcdj8h3dsP3pvWvKZN9qtt0JfulPW_8z3M130_assertion description "[Evidence for a locus (EJM1) in the HLA region of chromosome 6p predisposing to idiopathic generalized epilepsy (IGE) in the families of patients with juvenile myoclonic epilepsy (JME) has been obtained in two previous studies of separately ascertained groups of kindreds.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498253.RATluamM7Onpcdj8h3dsP3pvWvKZN9qtt0JfulPW_8z3M130_provenance.
- NP498254.RAbsDQKD5qV6HLReObNqAjuuBsCdsgiUemjlbC70RDAN4130_assertion description "[Mutations in WNK1 and WNK4 cause familial hypertension, the Gordon syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498254.RAbsDQKD5qV6HLReObNqAjuuBsCdsgiUemjlbC70RDAN4130_provenance.
- NP498256.RAc5eR-UvTT9j3X3pTYngNAE3ILroDZZ1ZTNJe4B2g8q4130_assertion description "[Monitored noninvasively through radioiodine-based single-photon emission computed tomography/computed tomography, intratumorally virus-delivered NIS has concentrated the radioiodine in the MV-NIS-treated tumors in the FaDu mouse xenograft model of human SCCHN, and the antitumor effect could be boosted significantly (p<0.05) either with concomitant cyclophosphamide therapy or with appropriately timed administration of radioiodine (131)I. MV-NIS could be a promising new anticancer agent that may substantially enhance the outcomes of standard therapy after intratumoral administration in patients with locally advanced SCCHN.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498256.RAc5eR-UvTT9j3X3pTYngNAE3ILroDZZ1ZTNJe4B2g8q4130_provenance.
- NP498257.RAaqMAzO7pmYfqa461oZKzwkkdrV0qGeNWjLIxFlfRbH4130_assertion description "[To investigate whether BLM was involved in cellular responses to DNA damage Bloom's syndrome fibroblasts were treated with either UV or ionizing radiation and the levels of p53 and two of its down stream effectors, p21waf1/cip1 and hdm2, were determined by western blot analysis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498257.RAaqMAzO7pmYfqa461oZKzwkkdrV0qGeNWjLIxFlfRbH4130_provenance.
- NP498261.RAY2liXB9L3gk7RkR-jUR4-O5Y_CsAbDQTEMg8BxGI1MU130_assertion description "[We report an unusual case of a white man with a CD56-positive T-cell lymphoma in the ileum.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498261.RAY2liXB9L3gk7RkR-jUR4-O5Y_CsAbDQTEMg8BxGI1MU130_provenance.
- NP498271.RARzUyso3sS9Ev3pgIL19Ks-ngd1AMLcyIZbtW-x07-qI130_assertion description "[Value of MLH1 and MSH2 mutations in the appearance of Muir-Torre syndrome phenotype in HNPCC patients presenting sebaceous gland tumors or keratoacanthomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498271.RARzUyso3sS9Ev3pgIL19Ks-ngd1AMLcyIZbtW-x07-qI130_provenance.
- NP498274.RAfNQvrEAIu8Z7vJsPPb52_bAU0V0fhcAInLNbxdmsEdc130_assertion description "[Importantly, a clear loss of function could be observed in the cells carrying the Crohn-associated variant L1007fsinsC, whereas the NOD2(wt) cells showed differential regulation of growth factors, chemokines, and several antagonists of NF-κB (e.g., TNFAIP3 [A20] and IER3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498274.RAfNQvrEAIu8Z7vJsPPb52_bAU0V0fhcAInLNbxdmsEdc130_provenance.
- NP498277.RAQwiyJ3hCnlKs8cUvCb1tM97MH5b8pvlKwA9h3WmOBj4130_assertion description "[Activation of PI3K/AKT pathway correlates with poor prognosis in patients with neuroblastoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498277.RAQwiyJ3hCnlKs8cUvCb1tM97MH5b8pvlKwA9h3WmOBj4130_provenance.
- NP498278.RAfFn3gg0UnVuguybifD5H-TJZe0_bp1qgrJ_uqb_ctKw130_assertion description "[After sequential MALDI-TOF-MASS analysis, immuno-positive spots of 48 kDa (pI 7.3-7.8) detected from HE patient sera were identified as a novel autoimmuno-antigen, alpha-enolase, harboring several modifications.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498278.RAfFn3gg0UnVuguybifD5H-TJZe0_bp1qgrJ_uqb_ctKw130_provenance.
- NP498283.RAecIIYeZT1dto7iP87g7sR6Oadq5rQEFyp0Euo13p5kw130_assertion description "[Restin was also highly expressed in anaplastic large-cell lymphoma (so-called Ki-1 lymphoma).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498283.RAecIIYeZT1dto7iP87g7sR6Oadq5rQEFyp0Euo13p5kw130_provenance.
- NP498286.RAaOTlyn9BYRPKifdW69pad23Ym4Rtu93zLexK_A2AFEs130_assertion description "[To further elucidate the mechanism by which PLCE1 mutations cause nephrotic syndrome, we sought to identify new protein interaction partners of PLCepsilon1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498286.RAaOTlyn9BYRPKifdW69pad23Ym4Rtu93zLexK_A2AFEs130_provenance.
- NP498287.RAT99eRPZGbmKjb-GOrGAkkLVDhmAZe_FQa0T1Lcb-xlg130_assertion description "[ANRIL-regulated networks were confirmed in 2280 individuals with and without coronary artery disease and functionally validated in primary cells from patients carrying the Chr9p21 risk allele.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498287.RAT99eRPZGbmKjb-GOrGAkkLVDhmAZe_FQa0T1Lcb-xlg130_provenance.
- NP498290.RAQjJw3rnPgHDKDv8T2mE8liRest04oWC5ebHrUia7Qt8130_assertion description "[CTB is a specific protective antigen component of a widely registered oral cholera vaccine as well as a promising vector for either giving rise to mucosal anti-infective immunity or for inducing peripheral anti-inflammatory tolerance to chemically or genetically linked foreign antigens administered mucosally.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498290.RAQjJw3rnPgHDKDv8T2mE8liRest04oWC5ebHrUia7Qt8130_provenance.
- NP498295.RATKMaOI3EXzeb5keGLhAcdDZrDyDlnk80k_OMbctBCds130_assertion description "[There was a close correlation between the expression of SphK1 and FAK or p-FAK and the co-expression of SphK1, FAK and p-FAK significantly associated with histological grade, Dukes' stage, lymph node metastasis and distant metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498295.RATKMaOI3EXzeb5keGLhAcdDZrDyDlnk80k_OMbctBCds130_provenance.
- NP498310.RATWOBp8BC0fzHHULspZZ_bweAVfjeaiWAQaEtU7aDPQQ130_assertion description "[The clinical manifestations of CTnI mutations that cause FHC are diverse, ranging from asymptomatic with high life expectancy to severe heart failure and sudden cardiac death.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498310.RATWOBp8BC0fzHHULspZZ_bweAVfjeaiWAQaEtU7aDPQQ130_provenance.
- NP498316.RASJ67CtG9AqixWYqVntGHfhSaANnVDYOG9s38vHZ-C2U130_assertion description "[Biochemical studies have pinpointed the pathogenesis resulting in the deficiency of the fatty aldehyde dehydrogenase (FALDH) component of the fatty alcohol NAD+ oxidoreductase complex.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498316.RASJ67CtG9AqixWYqVntGHfhSaANnVDYOG9s38vHZ-C2U130_provenance.
- NP498317.RAUHbPIUMEeRXBNSQrQnfzIYEDrm6-FNoracsvyTvXcp4130_assertion description "[Postmortem findings in 2 familial amyloidosis patients with the transthyretin variant (ATTR), Asp38Ala, are described Both showed cardiac failure, and progressive peripheral and autonomic neuropathy and died at the ages 82 and 57, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498317.RAUHbPIUMEeRXBNSQrQnfzIYEDrm6-FNoracsvyTvXcp4130_provenance.
- NP498318.RATm-6CqDGrE8ulCE83qq7GnGvZq-LgODfZv4AMQ4QVpw130_assertion description "[Analysis of clonal immunoglobulin heavy chain rearrangements in ocular lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498318.RATm-6CqDGrE8ulCE83qq7GnGvZq-LgODfZv4AMQ4QVpw130_provenance.
- NP498319.RAZufo341M-bDiGVylouJDgkqcsLcv7-Ha-_xtkcGHbYM130_assertion description "[Using meta-analysis across case-control and family trio (affected child and parental controls) studies of severe malaria from The Gambia and Malawi, we sought evidence of association in six Gs pathway candidate genes: adenosine receptor 2A (ADORA2A) and 2B (ADORA2B), beta-adrenergic receptor kinase 1 (ADRBK1), adenylyl cyclase 9 (ADCY9), G protein beta subunit 3 (GNB3), and regulator of G protein signalling 2 (RGS2).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498319.RAZufo341M-bDiGVylouJDgkqcsLcv7-Ha-_xtkcGHbYM130_provenance.
- NP498324.RAVsxyE0bIdmpOToOki_vwMKAIeOBRILFZF7gN608H754130_assertion description "[The inhibition of TNF-α may thus provide a new therapeutic approach to control tumour progression and bone destruction in MM patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498324.RAVsxyE0bIdmpOToOki_vwMKAIeOBRILFZF7gN608H754130_provenance.
- NP498328.RASlbYrVpeBD4e8ngeJgBar1SFAIIIfGbfBmElUd0Gof8130_assertion description "[We considered blood cells as a new potential source of transcriptional biomarkers for these metabolic disorders and examined whether blood cell mRNA levels of some selected genes (LEPR, INSR, CPT1A, SLC27A2, UCP2, FASN, and PPARα) were altered in overweight children and whether their expression levels could be defined as markers of the insulin-resistant or dyslipidemic state associated with overweight.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498328.RASlbYrVpeBD4e8ngeJgBar1SFAIIIfGbfBmElUd0Gof8130_provenance.
- NP498331.RAZv28fV3NrdVXuinJ1DOhLqQfpGgpdOk8aarWX2F4Aro130_assertion description "[Serum level of soluble intercellular adhesion molecule 1 in patients with chronic liver disease related to hepatitis C virus: A prognostic marker for responses to interferon treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498331.RAZv28fV3NrdVXuinJ1DOhLqQfpGgpdOk8aarWX2F4Aro130_provenance.
- NP498334.RARjYjuryEhlBnLK0QMWZNfWjcY_1HGmcl2z17TzsW2w0130_assertion description "[However, rates of KRAS and BRAF mutations in prostate carcinoma are reported to vary in different populations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498334.RARjYjuryEhlBnLK0QMWZNfWjcY_1HGmcl2z17TzsW2w0130_provenance.
- NP498335.RAY82qNO4fVscUR59SfGE8IzRrKmxgu1F0cGfTonov4nE130_assertion description "[Fcγ receptor genes have been suggested to play an important role in the pathogenesis of SLE and lupus nephritis (LN).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498335.RAY82qNO4fVscUR59SfGE8IzRrKmxgu1F0cGfTonov4nE130_provenance.
- NP498337.RAZx0rKHLv95diyVGWHQwXLBz67YT_D3IodB0i8UkQLAw130_assertion description "[The Wellcome Trust Case Control Consortium (WTCCC) genome-wide study found association of PTPN2 with three autoimmune diseases, among them is type 1 diabetes (T1D).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498337.RAZx0rKHLv95diyVGWHQwXLBz67YT_D3IodB0i8UkQLAw130_provenance.
- NP498338.RAVjQPwFbZ471fLuqwY9ZnBoWbxxqtGYR1RKz8DDWSvaA130_assertion description "[Five minutes of 5% CO(2) produced much lower increases in anxiety than did the 35% exposure, but a dose by group interaction suggested that increasing exposure increased anxiety preferentially in the high-risk subjects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498338.RAVjQPwFbZ471fLuqwY9ZnBoWbxxqtGYR1RKz8DDWSvaA130_provenance.
- NP498344.RAR02YBGVGg6neFw_XITswZ8wvDw4KuZEptRvN67KYzZc130_assertion description "[The neurofibromatosis 2 (NF2) tumor suppressor protein, schwannomin or merlin, is commonly lost upon NF2 gene mutation in benign human brain tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498344.RAR02YBGVGg6neFw_XITswZ8wvDw4KuZEptRvN67KYzZc130_provenance.
- NP498348.RAb1tlanzJo2gBnrSiuzyW1WLhH-IHh9PE6wqTIhJ0BGA130_assertion description "[Homoharringtonine (HHT) is a novel plant alkaloid that produced a complete hematologic remission (CHR) in 72% of patients with late chronic phase chronic myelogenous leukemia (CML).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498348.RAb1tlanzJo2gBnrSiuzyW1WLhH-IHh9PE6wqTIhJ0BGA130_provenance.
- NP498349.RAVK0N7yr9WSroUtXptFtiHSHs98YbXjAowU2VQ2dHSlM130_assertion description "[FGF7-like gene is associated with pericentric inversion of chromosome 9, and FGF7 is involved in the development of ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498349.RAVK0N7yr9WSroUtXptFtiHSHs98YbXjAowU2VQ2dHSlM130_provenance.
- NP498356.RActr8d8FDLvW8nk4Buk9izJEQ1bGUvMtB-GTHEqz1eNU130_assertion description "[MSI and MSS/EBV+ GCs displayed a significantly higher mean number of cytotoxic-activated TILs and apoptotic tumour cells than MSS/EBV- GCs (CD8+ TILs/HPF, 21.7 and 69.6 vs 6.4; T-cell intracellular antigen (TIA)-1+ TILs/HPF, 16.7 and 32.05 vs 5.2; granzyme B+ TILs/HPF, 7.5 and 8.6 vs 0.8; perforin+ TILs/HPF, 5.9 and 9.2 vs 0.9; and M30 IR tumour cells, 5.9 and 2.9 vs 2.3%).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498356.RActr8d8FDLvW8nk4Buk9izJEQ1bGUvMtB-GTHEqz1eNU130_provenance.
- NP498362.RAZM9W3uKG3eB5LzV8ooH0-c9O3HU0P0g0dC5uOyiwJzQ130_assertion description "[The lack of 17betaHSD-2 expression in endometriosis is not due to alterations in the levels of immunoreactive progesterone or estrogen receptors in this tissue and may be related to an inhibitory aberration in the signaling pathway that regulates 17betaHSD-2 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498362.RAZM9W3uKG3eB5LzV8ooH0-c9O3HU0P0g0dC5uOyiwJzQ130_provenance.
- NP498363.RAYU4dRYZ70E90Ul4LEBta1Fgfh7NxamRS34XrSy7Q2wU130_assertion description "[No association between bipolar disorder risk polymorphisms in ANK3 and CACNA1C and common migraine.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498363.RAYU4dRYZ70E90Ul4LEBta1Fgfh7NxamRS34XrSy7Q2wU130_provenance.
- NP498366.RATaiZuUQ5-Hpuvhls1qqnW_eUmaA_J6BcMHN2QFd0x1Q130_assertion description "[We used a hierarchical model approach to include prior genetic knowledge of the specific and found that variants in CNTF, in its receptor CNTFR, and in NTRK2 were significantly associated with a lower age at onset of the ED.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498366.RATaiZuUQ5-Hpuvhls1qqnW_eUmaA_J6BcMHN2QFd0x1Q130_provenance.
- NP498370.RAeVT98hiIP0jXFIdL8yxyxqTrG_wVf5DDCGWBjXOK75w130_assertion description "[However, Restin was present in Reed-Sternberg cells and variants thereof in Hodgkin's disease, with the exception of the lymphocyte-predominant, paragranuloma subtype.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498370.RAeVT98hiIP0jXFIdL8yxyxqTrG_wVf5DDCGWBjXOK75w130_provenance.
- NP498381.RAZbd2YGw8vLwoiHLOuV21H3ZKGZuKegINRth0JxSKwAM130_assertion description "[In order to explore the underlying mechanism causing the disease after HTLV-I infection, we analyzed CD44 variant expression on peripheral blood mononuclear cells (PBMC) and in the spinal cord specimens from patients with HAM/TSP, and compared them with those from other HTLV-I-infected individuals and controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498381.RAZbd2YGw8vLwoiHLOuV21H3ZKGZuKegINRth0JxSKwAM130_provenance.
- NP498382.RAXqQDguRKq8q884jg4TeOa_BzzWTZMxkYhuEZ6Aa7LdQ130_assertion description "[Recent evidence suggests that the transcriptional coactivator peroxisome proliferator activated receptor gamma coactivator 1alpha (PGC-1alpha) is involved in the pathology of Huntington's Disease (HD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498382.RAXqQDguRKq8q884jg4TeOa_BzzWTZMxkYhuEZ6Aa7LdQ130_provenance.
- NP498383.RAUYHDOSZ2E8lWbHzY8oXVQPTWrax0REQ5eKZzNeMCu6Y130_assertion description "[No evidence for mutations of CTCFL/BORIS in Silver-Russell syndrome patients with IGF2/H19 imprinting control region 1 hypomethylation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498383.RAUYHDOSZ2E8lWbHzY8oXVQPTWrax0REQ5eKZzNeMCu6Y130_provenance.
- NP498385.RAc6C5n1gH_QpTYi6Dm-FtbP4ZVsStDoROdQGipS-QYAU130_assertion description "[We propose that GCKR is a susceptibility gene in Japanese families with clustered diabetes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498385.RAc6C5n1gH_QpTYi6Dm-FtbP4ZVsStDoROdQGipS-QYAU130_provenance.
- NP498387.RAXHL2FBxSoBvVK-jlwuoo-7l-CmHJk5wzngq08NyRLIE130_assertion description "[Recently, common genetic variants in the SPAK gene have been identified as HTN susceptibility factors in the general population, suggesting that altered WNK-SPAK signaling plays an important role in essential HTN.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498387.RAXHL2FBxSoBvVK-jlwuoo-7l-CmHJk5wzngq08NyRLIE130_provenance.
- NP498388.RAb4_1ul_oVuxu1FOzPfllZh4yl87_QR0Z7d-IAI_edYo130_assertion description "[Also, the observed association of SYNGR1 with both SCZ and BPAD suggests the likely involvement of a common pathway in the etiology of these disorders.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498388.RAb4_1ul_oVuxu1FOzPfllZh4yl87_QR0Z7d-IAI_edYo130_provenance.
- NP498391.RAZhOotS6_Ynvtu8uNW4b_DU94h4n478Oulk_psegQWIQ130_assertion description "[This raises the possibility that SFRP4 may be used both diagnostically and therapeutically in epithelial ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498391.RAZhOotS6_Ynvtu8uNW4b_DU94h4n478Oulk_psegQWIQ130_provenance.
- NP498392.RAXqNkeYIWTThHrc7mSpwEJArcLzfsIKOEpnelEt0JtNY130_assertion description "[In this study, cloned canine IL-6 cDNA was used as a molecular probe to study the regulation of IL-6 in an awake canine model of myocardial ischemia and reperfusion.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498392.RAXqNkeYIWTThHrc7mSpwEJArcLzfsIKOEpnelEt0JtNY130_provenance.
- NP498396.RAbowniQj8WrJQwPu9WZQVhjZowZyKJIlo5wyfFPnIuJs130_assertion description "[Osteogenesis imperfecta (OI) is a heritable bone fragility disorder that in the majority of cases is caused by mutations in COL1A1 or COL1A2, the genes that encode the two collagen type I alpha chains, alpha1(I) and alpha2(I).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498396.RAbowniQj8WrJQwPu9WZQVhjZowZyKJIlo5wyfFPnIuJs130_provenance.
- NP498398.RAQhclnmiobSMz9Z0D6L7gf_7DG2Y49YBGlk69sohwpTI130_assertion description "[We propose that the human DIA gene is one of the genes responsible for POF and that it affects the cell divisions that lead to ovarian follicle formation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498398.RAQhclnmiobSMz9Z0D6L7gf_7DG2Y49YBGlk69sohwpTI130_provenance.
- NP498403.RARjtyBWZ40A1Rhvkn5AyZ--mIEr_XCs7vaBVMJyRvOdY130_assertion description "[Alterations with aging and ischemia in nicotinic acetylcholine receptor subunits alpha4 and beta2 messenger RNA expression in postmortem human putamen. Implications for susceptibility to parkinsonism.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498403.RARjtyBWZ40A1Rhvkn5AyZ--mIEr_XCs7vaBVMJyRvOdY130_provenance.
- NP498407.RAVvLA5KeRrhq-MkKd7vbCmyvuMU2_uGAkWO43NOCaymw130_assertion description "[Gene expression profiles from cDNA microarray analyses of the same stromal tissue samples revealed that putative targets of these miRNA clusters, predicted by Target Scan, such as TGFBR2, SMAD2, and BMP family genes, were significantly downregulated in cancer stromal tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498407.RAVvLA5KeRrhq-MkKd7vbCmyvuMU2_uGAkWO43NOCaymw130_provenance.
- NP498408.RARKK6H9YDnkfWRd_TU-HjRmiind_ni1J5lOMShG5uE44130_assertion description "[Opa interacting protein 5 (OIP5) is a novel cancer-testis specific gene in gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498408.RARKK6H9YDnkfWRd_TU-HjRmiind_ni1J5lOMShG5uE44130_provenance.
- NP498412.RAXRveBa0hQmASfrEknRafeiEiGqjKvXQIZPGGk-KZJc4130_assertion description "[Hypoxia is one of the basic characteristics of the colorectal cancer and HIF1 plays a central role in tumor hypoxia adaptation and controls the expression of a variety of genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498412.RAXRveBa0hQmASfrEknRafeiEiGqjKvXQIZPGGk-KZJc4130_provenance.
- NP498416.RAcWp-S19DzssB3HfSEF1ao-EGiK1AuZ0hutcyIap3AUw130_assertion description "[We studied CD4(+) T lymphocyte proliferation together with interferon (IFN)-gamma and interleukin (IL)-10 production from peripheral blood mononuclear cells in response to 4 HCV antigens (core, NS3, NS4, and NS5) in 25 patients with chronic hepatitis C undergoing antiviral therapy with IFN alone or in combination with ribavirin, prospectively, before, during, and after treatment.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498416.RAcWp-S19DzssB3HfSEF1ao-EGiK1AuZ0hutcyIap3AUw130_provenance.
- NP498419.RARsRgMapCyFewaliQNRLJVckbp1sD3U8Xf43CFlhwP-E130_assertion description "[The role of endothelial nitric oxide synthase (eNOS) genetic variants in European patients with intracranial aneurysms.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498419.RARsRgMapCyFewaliQNRLJVckbp1sD3U8Xf43CFlhwP-E130_provenance.
- NP498425.RAQmsPQH-snbsw5x_7mBqz-GRVQxFxpFLaXrpFLhieuXw130_assertion description "[KIF14 also showed high expression in other cancers, notably an association with survival in lung tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498425.RAQmsPQH-snbsw5x_7mBqz-GRVQxFxpFLaXrpFLhieuXw130_provenance.
- NP498427.RAcpdNcNVFTGEM4eddcOYKMYcWmIX1aZM8hdJaD6YUwVA130_assertion description "[Mutations of the pendrin gene can lead to syndromic and non-syndromic hearing loss with EVA (enlarged vestibular aqueduct).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498427.RAcpdNcNVFTGEM4eddcOYKMYcWmIX1aZM8hdJaD6YUwVA130_provenance.
- NP498445.RAWG4QxldEvegivyK7Du5Zs5AciMexZkfk_EnF-z9A2kM130_assertion description "[Previously, it has been shown that interleukin (IL)-8 is elevated in the ascites of patients with ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498445.RAWG4QxldEvegivyK7Du5Zs5AciMexZkfk_EnF-z9A2kM130_provenance.
- NP498446.RAUlyDCBYfGjOvAXt5JY3GiRThA_nGbY0KNbl9yQjOG0Y130_assertion description "[However, there were differences in the k/l ratio (1.2:1 for SMZL and 4.5:1 for WM) and in some markers such as CD22 and CD11c, which were overexpressed in patients with SMZL compared with patients with WM, whereas CD25 was more frequently positive in WM (88% vs. 44%).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498446.RAUlyDCBYfGjOvAXt5JY3GiRThA_nGbY0KNbl9yQjOG0Y130_provenance.
- NP498449.RAfdoHJX9namQAv6VGn3hLxKli_dg6jW8Ak_6bMpe9DOo130_assertion description "[Increasing levels of MYC and MET co-amplification during tumor progression of a case of gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498449.RAfdoHJX9namQAv6VGn3hLxKli_dg6jW8Ak_6bMpe9DOo130_provenance.
- NP498451.RARz-NytTnSMx1tBtMytx0bCUxGcZZi1tDaAq5_jvSsBk130_assertion description "[The SCZ (schizophrenia)-associated GABA(A) receptor (gamma-aminobutyric acid type A receptor) beta(2) subunit gene GABRB2 was recently associated with BPD (bipolar disorder).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498451.RARz-NytTnSMx1tBtMytx0bCUxGcZZi1tDaAq5_jvSsBk130_provenance.
- NP498458.RAXlbwkbQ0tD518i_2mkKT0qHIJM6cGHkmCerIupWBD-U130_assertion description "[Taken together with our previous finding that matriptase is a proteolytic activator of PDGF D, this study provides a molecular insight into signal amplification of the proteolytic network and PDGF signaling loop during cancer progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498458.RAXlbwkbQ0tD518i_2mkKT0qHIJM6cGHkmCerIupWBD-U130_provenance.
- NP498459.RAQPB1s9GnvPGm2gQuADubrjUW4bQv1soakaSnzyZ7N2Y130_assertion description "[Polymorphism of the vitamin D receptor (VDR) gene has recently been shown to be related to bone mineral density, and also associated with hyperparathyroidism and risk of prostatic carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498459.RAQPB1s9GnvPGm2gQuADubrjUW4bQv1soakaSnzyZ7N2Y130_provenance.
- NP498460.RAaNDxebUr0L2AP27T8M7fAKme1k7UQDCnjYCn6_KfLfY130_assertion description "[The DNA content and S-phase fraction (SPF) of pathological paraffin-embedded lymph node tissue from 47 patients with poor prognosis non-Hodgkin's lymphoma (NHL) were analyzed by flow cytometry (FCM).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498460.RAaNDxebUr0L2AP27T8M7fAKme1k7UQDCnjYCn6_KfLfY130_provenance.
- NP498462.RAYhFmbiUCASp7lfVHbtP7DbYSBKTTmc9pdt6GCwYSQc8130_assertion description "[Our findings suggest that both IGF-I and IGF-II are associated with an increased risk of screen-detected prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498462.RAYhFmbiUCASp7lfVHbtP7DbYSBKTTmc9pdt6GCwYSQc8130_provenance.
- NP498463.RARsNfyaXEC3nnEYXUdDByWs3d25XGGF2dqr4R_cD9D68130_assertion description "[These data suggest that the C(-634)G polymorphism in the 5'UTR of the VEGF gene is a novel genetic risk factor for diabetic retinopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498463.RARsNfyaXEC3nnEYXUdDByWs3d25XGGF2dqr4R_cD9D68130_provenance.
- NP498464.RAXyCtaPQtKwnNYDegrDSCMFZU1-rdhVk5u4vbor3IpDU130_assertion description "[Meanwhile, MDR1 gene expression in gallbladder carcinoma is correlated with some biological characteristics, takes part in the carcinogenesis of gallbladder tissues, and acts as a valuable biomarker of prognosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498464.RAXyCtaPQtKwnNYDegrDSCMFZU1-rdhVk5u4vbor3IpDU130_provenance.
- NP498466.RATuzfPQVvu0xQbejmSLS2uiz0XyI5i0U5242VImzmmSQ130_assertion description "[In informative cases with suitable internal controls, all primary tumors (n = 60), lymph node (n = 7), and bone metastases (n = 5) expressed the ERbeta at variable degree.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498466.RATuzfPQVvu0xQbejmSLS2uiz0XyI5i0U5242VImzmmSQ130_provenance.
- NP498467.RAYI84Caxc9ROoQb2XE67tcz1bXxA3ZDZz_CQy_VGNeUI130_assertion description "[The purpose of our study was to determine the likelihood of MMR defects (MSH2, MSH6, MLH1) in women with synchronous endometrial and ovarian cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498467.RAYI84Caxc9ROoQb2XE67tcz1bXxA3ZDZz_CQy_VGNeUI130_provenance.
- NP498468.RAW-7MHvQ_Ftx8cqXcDvEubnbVJjH3TXCWYZVU3LyXuEc130_assertion description "[BRUNOL3 appears to be an important factor for thymus development and is therefore a candidate gene for the thymus hypoplasia/aplasia seen in partial monosomy 10p patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498468.RAW-7MHvQ_Ftx8cqXcDvEubnbVJjH3TXCWYZVU3LyXuEc130_provenance.
- NP498471.RAW9jtNXnEGL5VH26lJJWIu-mUjeAdYPNDK6I5iiRSxEA130_assertion description "[The locus partially overlaps with the USH1 locus, USH1H, a novel unnamed USH2 locus, and the non-syndromic deafness locus DFNB48.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498471.RAW9jtNXnEGL5VH26lJJWIu-mUjeAdYPNDK6I5iiRSxEA130_provenance.
- NP498472.RAapCARw82fyvgHi0G4qY0lZxF7-4xqXpJ5DPkSZnnnic130_assertion description "[Homozygous protein C deficiency--management with protein C concentrate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498472.RAapCARw82fyvgHi0G4qY0lZxF7-4xqXpJ5DPkSZnnnic130_provenance.
- NP498477.RAYhuasFmKkNzDgVwbSjNnP-m0PGTsVsazO0eB7JrpFQA130_assertion description "[Analysis of aberrancies in expression of cytochrome c oxidase subunit I showed that, compared with nonneoplasia, the patients with neoplasia had a higher mean incidence of crypts having decreased expression (1.7 versus 22.8, P = 0.03) and a higher mean incidence having crypt-restricted loss (0.6 versus 3.2, P = 0.06).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498477.RAYhuasFmKkNzDgVwbSjNnP-m0PGTsVsazO0eB7JrpFQA130_provenance.
- NP498482.RAZ5nZwkWJvDGdy15h7FwaE1VxdWME06KK7wwnOPtAsq8130_assertion description "[The expression of mPGES-1 and COX-2 was correlated in tumour cells and vascular endothelium, and with prognostic parameters in breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498482.RAZ5nZwkWJvDGdy15h7FwaE1VxdWME06KK7wwnOPtAsq8130_provenance.
- NP498485.RAacETwksnxY6x-zAK3zY3v-r-i77ZZTFXMQvVQyvqpvU130_assertion description "[Moreover, deficiency in MPST activity has been suggested to be responsible for a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498485.RAacETwksnxY6x-zAK3zY3v-r-i77ZZTFXMQvVQyvqpvU130_provenance.
- NP498492.RAaPLn5bJG7Uhp4hADNW0DvuevcFEkmt34nA4XFDtF-f4130_assertion description "[We attempted to investigate whether the Val158Met polymorphism of COMT was associated with the risk of prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498492.RAaPLn5bJG7Uhp4hADNW0DvuevcFEkmt34nA4XFDtF-f4130_provenance.
- NP498501.RAfic53ToJCmDtaxYfWoiF0UF-I_1SOb0tP-BCpR22EtU130_assertion description "[We aimed to examine the association between the aromatase polymorphism g.132810C>T, and the estrogen receptor polymorphisms g.156705T>C and g.156751A>G, and the risk of BP-related ONJ.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498501.RAfic53ToJCmDtaxYfWoiF0UF-I_1SOb0tP-BCpR22EtU130_provenance.
- NP498502.RAQp8eT7yarwG-CxLmrnsHkZG3jXqLenBu2BAaKBAwuGw130_assertion description "[Scores computed from the cell-by cell features and the clinical grade of CIN/SIL were highly correlated, as were those of the architectural features and the clinical grade of CIN/SIL.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498502.RAQp8eT7yarwG-CxLmrnsHkZG3jXqLenBu2BAaKBAwuGw130_provenance.
- NP498505.RAT5eB91oHYhojfIZBY-mfM9VLD5SiR9vnsPatdDnEBW0130_assertion description "[In multivariable models, dMMR was independently associated with delayed TTR (hazard ratio = 0.72, 95% confidence interval = 0.56 to 0.91, P = .005) and improved DFS (P = .035) and OS (P = .031).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498505.RAT5eB91oHYhojfIZBY-mfM9VLD5SiR9vnsPatdDnEBW0130_provenance.
- NP498510.RAYKtwc1e-HaBJwnoBtm2k0_f2wWMuWrh5Es8RIGi6GvM130_assertion description "[For the four trisomy 15 mosaics detected at CVS, molecular analysis was performed on direct amniotic fluid cell lysates for prospective diagnosis of UPD at 14-16 weeks' gestation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498510.RAYKtwc1e-HaBJwnoBtm2k0_f2wWMuWrh5Es8RIGi6GvM130_provenance.
- NP498513.RAWXJEwQ9uQXEDpoztLAvWxxaAiw1fQ4YxNRvCVD1dnnw130_assertion description "[Our data suggest that the P48T mutation of p16 is a strong melanoma-predisposing factor, but the fact that the heterozygous mutant parents have not yet exhibited melanoma or atypical moles indicates that the penetrance of this allele might depend on modifying factors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498513.RAWXJEwQ9uQXEDpoztLAvWxxaAiw1fQ4YxNRvCVD1dnnw130_provenance.
- NP498514.RASmPFVw5U9aTixwZaDCbFl-RK_2bPqUBpJGg70nFC-4Q130_assertion description "[No significant differences were found between obese BED and obese non-BED individuals, suggesting that this polymorphism does not genetically distinguish these two phenotypes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498514.RASmPFVw5U9aTixwZaDCbFl-RK_2bPqUBpJGg70nFC-4Q130_provenance.
- NP498515.RAchmaM6TWT-OX-7M_otEh4BLJ6QQdzt5fGaD2H36JSiM130_assertion description "[These reports clearly point to genes located in the MHC region, in particular HLA-DRB1*04 alleles, and other key members of the immune and inflammatory response (including cytokines, adhesion molecules and regulators of innate immunity), as crucial players in the development and progression of GCA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498515.RAchmaM6TWT-OX-7M_otEh4BLJ6QQdzt5fGaD2H36JSiM130_provenance.
- NP498531.RAewV6Omr3fYqXtXm0PcW9CrHzgm2m29S4Y7wHH-27uO4130_assertion description "[Both Raf/MEK/ERK and PI3K/Akt/mTOR pathways are over-expressed and/or over-activated in pituitary tumours: these pathways share a common root, including initial activation related to the tyrosine kinase receptor, and we speculate that a change to these receptors or their relationship to membrane matrix-related proteins may be an early event in pituitary tumourigenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498531.RAewV6Omr3fYqXtXm0PcW9CrHzgm2m29S4Y7wHH-27uO4130_provenance.
- NP498536.RAYY4XFLK6drMOfG3I9qwquB4638zb49X5egdWhFNOzp4130_assertion description "[Poly(ADP)-ribose polymerase inhibition: frequent durable responses in BRCA carrier ovarian cancer correlating with platinum-free interval.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498536.RAYY4XFLK6drMOfG3I9qwquB4638zb49X5egdWhFNOzp4130_provenance.
- NP498538.RAfQdLvuYxfJqGXPaMCBYui8Hx5rZo5sNVOx8ZQe1QFk8130_assertion description "[Desmin myopathy is a familial or sporadic disorder characterized by the presence of desmin mutations that cause skeletal muscle weakness associated with cardiac conduction block, arrhythmia and heart failure.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498538.RAfQdLvuYxfJqGXPaMCBYui8Hx5rZo5sNVOx8ZQe1QFk8130_provenance.
- NP498540.RAQzuRT7NO2ZAoA3sAskUbMpDg1Cs3jPjczpmtijtpl4A130_assertion description "[Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498540.RAQzuRT7NO2ZAoA3sAskUbMpDg1Cs3jPjczpmtijtpl4A130_provenance.
- NP498545.RAcK-dy4roOXy-OM3h75LW8L70xpynE4n9-YQLKMg1f5o130_assertion description "[Functional significance of Wnt inhibitory factor-1 gene in kidney cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498545.RAcK-dy4roOXy-OM3h75LW8L70xpynE4n9-YQLKMg1f5o130_provenance.