Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP498549.RAWOQZB3_L2ZmFM6Avom5sExUXJ2d0JH-uXF1rmiIsSf0130_assertion description "[The exact relationship between transforming growth factor beta-1 (TGFbeta-1) and the development of chronic graft nephropathy remains uncertain; however, it would appear that TGFbeta-1 is up-regulated at the protein and mRNA levels during the first year following cadaveric renal transplantation and the effect of 'high producer' gene polymorphisms may also be important.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498549.RAWOQZB3_L2ZmFM6Avom5sExUXJ2d0JH-uXF1rmiIsSf0130_provenance.
- NP498555.RAQVNO0_sv_PIQ3ULPlnpHT-gzLYQWTC6z-wSNoRsNBeY130_assertion description "[Screening for hot spots mutations in BRAF (exons 11 and 15) and NRAS (exons 2 and 3) was performed.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498555.RAQVNO0_sv_PIQ3ULPlnpHT-gzLYQWTC6z-wSNoRsNBeY130_provenance.
- NP498557.RAYZJVYOd8gPyGjPchbvG0Prpc9RLPCit-uMx7Rk2B-90130_assertion description "[Global miRNA profiling identified 46 miRNAs at significantly altered levels (p ≤ 0.05) in the serum of TRansgenic Adenocarcinoma of Mouse Prostate (TRAMP) mice with advanced prostate cancer compared to healthy controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498557.RAYZJVYOd8gPyGjPchbvG0Prpc9RLPCit-uMx7Rk2B-90130_provenance.
- NP498562.RAWA11U0NfCG748nZe2vc-UHZxp-2ob57o7Ssw9Dfi1ls130_assertion description "[In conclusion, our findings suggest an essential contribution of combined KLF4 K409Q and TRAF7 mutations in the genesis of secretory meningioma and demonstrate a role for TRAF7 alterations in other non-NF2 meningiomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498562.RAWA11U0NfCG748nZe2vc-UHZxp-2ob57o7Ssw9Dfi1ls130_provenance.
- NP498568.RASgvgtbGTdFf2L-WPx1y6dlgm9lQAlV04CYG-jVIQe40130_assertion description "[AMDM is characterised by severe dwarfism with shortening of the middle and distal segments of the limbs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498568.RASgvgtbGTdFf2L-WPx1y6dlgm9lQAlV04CYG-jVIQe40130_provenance.
- NP498574.RAWdvyN0Vp3r1ebXvwWT-5Br_hWh0QTPUQkz-RnyvHAB0130_assertion description "[We could previously demonstrate an expression of HMGI-C mRNA in the peripheral blood of breast cancer patients for the first time.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498574.RAWdvyN0Vp3r1ebXvwWT-5Br_hWh0QTPUQkz-RnyvHAB0130_provenance.
- NP498576.RAVWhmr9yqjK8waDPJGiNoaksQDjK2mWZ0NAr29w-IPmA130_assertion description "[Because IL-17A and IL-17F, ligands for IL-17 receptor antagonist (IL-17RA), have been shown to mediate neutrophil migration into the lung in response to LPS or Gram-negative bacterial pneumonia, we hypothesized that IL-17RA signaling was critical for acute lung injury in response to pulmonary influenza infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498576.RAVWhmr9yqjK8waDPJGiNoaksQDjK2mWZ0NAr29w-IPmA130_provenance.
- NP498583.RAYyHL3ZUX7BydxJ0UweqfF_yQHqlnJ7Ovce-ooRJtY80130_assertion description "[We explored serum concentrations and mRNA expression of insulin-like-growth factor-1 (IGF-1) axis components in subcutaneous adipose tissue (SCAT) and peripheral monocytes (PM) of 18 healthy females, 11 obese non-diabetic females (OB) and 13 obese women with type 2 diabetes (T2DM) examined at baseline and after very-low-calorie diet (VLCD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498583.RAYyHL3ZUX7BydxJ0UweqfF_yQHqlnJ7Ovce-ooRJtY80130_provenance.
- NP498584.RAV57esp4jmMCJxoCKG121DDOLQcKqjV6p_O9rIf62wCo130_assertion description "[Expression of the hematopoietic growth factor receptor FLT3 (STK-1/Flk2) in human leukemias.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498584.RAV57esp4jmMCJxoCKG121DDOLQcKqjV6p_O9rIf62wCo130_provenance.
- NP498585.RAWmRNOrmVK_2RhAodW2uArSUQeLORL_xxyImwvB_M6sc130_assertion description "[The YB-1/Notch-3 interaction may be of particular relevance for inflammatory mesangioproliferative disease, as both proteins co-localize in an experimental nephritis model and receptor activation temporally and spatially correlates with YB-1 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498585.RAWmRNOrmVK_2RhAodW2uArSUQeLORL_xxyImwvB_M6sc130_provenance.
- NP498587.RAVQTGRvtoQ1Yqj_d82yCt5sBcwMTSCmV2vb14jmmEsY8130_assertion description "[The aim was to examine the association between alcohol intake and diabetes and intermediate CHD risk factors in relation to selected ADH and ALDH gene variants.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498587.RAVQTGRvtoQ1Yqj_d82yCt5sBcwMTSCmV2vb14jmmEsY8130_provenance.
- NP498591.RAUHtBOL3-qEDk2FNMdaQVuvCrIHodGz2SBwQjB6Xxmu8130_assertion description "[The current study was designed: (i) to characterize the cpk-associated biliary disease in affected F(2) homozygotes from intercrosses with either CAST or D2; and (ii) to evaluate focal biliary cysts identified in heterozygotes from a D2-cpk congenic strain.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498591.RAUHtBOL3-qEDk2FNMdaQVuvCrIHodGz2SBwQjB6Xxmu8130_provenance.
- NP498599.RAQdcsAvlLZBtQdiktJJ_yMpypeUqqQFthafDgjNUJW7E130_assertion description "[We used neuronal and brain endothelial cell injury models and middle cerebral artery occlusion in mice to compare efficacy and safety of drotrecogin-alfa activated and human 3K3A-APC, an APC nonanticoagulant mutant.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498599.RAQdcsAvlLZBtQdiktJJ_yMpypeUqqQFthafDgjNUJW7E130_provenance.
- NP498607.RAT7dYCiRRFzt_wFIi6tBQmnvj0QRLQPrzHWMqexKoqEQ130_assertion description "[ACA11 suppressed oxidative stress, afforded resistance to chemotherapy, and increased the proliferation of MM cells, demonstrating that ACA11 is a critical target of the t(4;14) translocation in MM and suggesting an oncogenic role in other cancers as well.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498607.RAT7dYCiRRFzt_wFIi6tBQmnvj0QRLQPrzHWMqexKoqEQ130_provenance.
- NP498615.RAceQG23V8hyCDxdmFUqnWXOpa1uiVWWYfldD0rM0ubVs130_assertion description "[The non-receptor tyrosine kinase focal adhesion kinase (FAK) was found to be co-associated with and highly activated by EphB2 expression, and FAK activation facilitated focal adhesion formation, cytoskeleton structure change and cell migration in EphB2-expressing GBM neurosphere cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498615.RAceQG23V8hyCDxdmFUqnWXOpa1uiVWWYfldD0rM0ubVs130_provenance.
- NP498616.RAbHetzDcLdfmAomwuL7RpfLny61D8GuKK72fHXp62QBg130_assertion description "[NRP/B also enhanced Nrf2-mediated NAD(P)H:quinine oxidoreductase 1 promoter activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498616.RAbHetzDcLdfmAomwuL7RpfLny61D8GuKK72fHXp62QBg130_provenance.
- NP498617.RAaSkMdxhI7zHqsnlS55hN27QDFzFR2Fx3xgjf11EQ7B8130_assertion description "[The relationship of the ALDH2 genotype with proliferative retinopathy is interesting, because it resembles that of chlorpropamide alcohol flushing with severe diabetic retinopathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498617.RAaSkMdxhI7zHqsnlS55hN27QDFzFR2Fx3xgjf11EQ7B8130_provenance.
- NP498618.RAf3xnr6E8IHy1hA6f11JHMwijkloKSRXfOLlKsagaVmE130_assertion description "[To clarify the significance of GPI-AP(-) T cells in BMF, peripheral blood from 562 patients was examined for the presence of CD48(-) CD59(-) CD3(+) cells using high-resolution flow cytometry (FCM), and the GPI-AP(-) T cells were characterized with regard to their phenotype and sensitivity to inhibitory molecules, including herpesvirus entry mediator (HVEM) and a myelosuppressive cytokine, TGF-β.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498618.RAf3xnr6E8IHy1hA6f11JHMwijkloKSRXfOLlKsagaVmE130_provenance.
- NP498626.RARVHcFwy-XDgDdUj7Ad6prppPdp6OXpmlb8T9qjNrX0w130_assertion description "[Genetic ablation of Insl3 or its G protein-coupled receptor, leucine-rich repeat-containing G-protein-coupled receptor (Lgr8), causes cryptorchidism in mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498626.RARVHcFwy-XDgDdUj7Ad6prppPdp6OXpmlb8T9qjNrX0w130_provenance.
- NP498630.RAX5h-_EC9T7YISLW3-SsXq3zcG5QyNYkBxjbzAvGt4-M130_assertion description "[Within the group of differentially expressed genes were SPARC, DAB2, CP, EVI1, ELF3, and EHD2, known to play a role in ovarian cancer, genes implicated in other cancers, such as GREM1 and GLIPR1, as well as genes not previously reported in a cancer context such as AKAP2 and ATAD4.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498630.RAX5h-_EC9T7YISLW3-SsXq3zcG5QyNYkBxjbzAvGt4-M130_provenance.
- NP498642.RASFH1iasIqKmWO2J5zhTuZldGOtl_ALxEbxb8jDveUBg130_assertion description "[High prevalence, recurrent BRAF mutations in LCH indicate that it is a neoplastic disease that may respond to RAF pathway inhibitors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498642.RASFH1iasIqKmWO2J5zhTuZldGOtl_ALxEbxb8jDveUBg130_provenance.
- NP498643.RAZJFSbVOexQXPQLoUnmiYXKpN9p0WalM-AtP0bU6_jzY130_assertion description "[Increased miR-222 in H. pylori-associated gastric cancer correlated with tumor progression by promoting cancer cell proliferation and targeting RECK.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498643.RAZJFSbVOexQXPQLoUnmiYXKpN9p0WalM-AtP0bU6_jzY130_provenance.
- NP498646.RAdsEkYvPlW4O3ompqSTmuvqdc9F5csVzdKkcitW7iaDw130_assertion description "[We now report a case of Hb H hydrops foetalis syndrome, caused by the inheritance of a hitherto novel alpha-globin gene point mutation (codon 35 TCC-->CCC or Serine-->Proline) and an alpha-thalassaemia deletion of the Filipino type removing all zeta-alpha-globin genes on the other chromosome 16.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498646.RAdsEkYvPlW4O3ompqSTmuvqdc9F5csVzdKkcitW7iaDw130_provenance.
- NP498648.RAa9NXoPybpsFK5OKaXw-fgpghc-6bX89uTfxbsrqUBlI130_assertion description "[As a functional indicator of Tcf-4 protein, quantitative binding analysis with nuclear extracts from small intestine biopsies to a Tcf-4 high-affinity binding site in the HD-5 and HD-6 promoters showed significantly reduced activity in ileal CD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498648.RAa9NXoPybpsFK5OKaXw-fgpghc-6bX89uTfxbsrqUBlI130_provenance.
- NP498651.RAZHt3AsZnYjDExco9tsljrQixbYDDREheI5MBfAFlA1w130_assertion description "[The conversion of Pseudomonas aeruginosa PAO to the mucoid phenotype has been reported for a chronic pulmonary infection model in rats (D. E. Woods, P. A. Sokol, L. E. Bryan, D. G. Storey, S. J. Mattingly, H. J. Vogel, and H. Ceri, J. Infect.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498651.RAZHt3AsZnYjDExco9tsljrQixbYDDREheI5MBfAFlA1w130_provenance.
- NP498652.RASJBoFvnG7aTbd2Yw1DbasSzfF7NQt7qvvkbUPcKeT9o130_assertion description "[Autosomal dominant hyper-IgE syndrome (AD-HIES), characterised by eczema, increased susceptibility to skin and lung infections, elevated IgE and skeletal abnormalities is associated with heterozygous STAT3 mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498652.RASJBoFvnG7aTbd2Yw1DbasSzfF7NQt7qvvkbUPcKeT9o130_provenance.
- NP498654.RAZ6aSqh_BdZt8mr1Xtv891VjN9oRIp_gtej14p-6nv3Q130_assertion description "[PAH was assessed via measurement of right ventricular systolic pressure (RVSP), pulmonary vascular remodelling (PVR), and right ventricular hypertrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498654.RAZ6aSqh_BdZt8mr1Xtv891VjN9oRIp_gtej14p-6nv3Q130_provenance.
- NP498657.RAXa5wtTikn0fUEgachXfLVDe1OBhQ-YEg_hPKKdudh6A130_assertion description "[Seventy-two paraffin-embedded primary CRC and paired SLN were evaluated by PNA clamp PCR for K-ras mutations.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498657.RAXa5wtTikn0fUEgachXfLVDe1OBhQ-YEg_hPKKdudh6A130_provenance.
- NP498664.RAbaEld9GYKe0L_jZx1ACmAUYn-ofisUtKwJVVzUR5lZ0130_assertion description "[We observed a significant association of the deletion polymorphism of ACE gene with renal insufficiency, hypertension and severe glomerular lesions at biopsy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498664.RAbaEld9GYKe0L_jZx1ACmAUYn-ofisUtKwJVVzUR5lZ0130_provenance.
- NP498665.RAek5pmS61ySXvWkkIHLaIsvhrOSmcYV-ePzXjWdFDC7c130_assertion description "[Major histocompatibility complex (MHC) class II genes, and probably also MHC class I genes, regulate both human multiple sclerosis and rodent experimental autoimmune encephalomyelitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498665.RAek5pmS61ySXvWkkIHLaIsvhrOSmcYV-ePzXjWdFDC7c130_provenance.
- NP498669.RAVVzE57eBe8rLCyvkMdg1V-diQWaJlSeVJeyqFBTmgzs130_assertion description "[Infection with H. pylori consistently upregulated annexin II, S100 A7, Rho-GTP, and IQGAP-1, whereas SSTR-1 was downregulated upon H. pylori infection.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498669.RAVVzE57eBe8rLCyvkMdg1V-diQWaJlSeVJeyqFBTmgzs130_provenance.
- NP498670.RAVMYUCgwZqItp4ambZEK8rYm83n35SFwu5CSZLkVLBck130_assertion description "[The ability of CO to reverse PAH requires functional endothelial nitric oxide synthase (eNOS/NOS3) and NO generation, as indicated by the inability of CO to reverse chronic hypoxia-induced PAH in eNOS-deficient (nos3-/-) mice versus wild-type mice.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498670.RAVMYUCgwZqItp4ambZEK8rYm83n35SFwu5CSZLkVLBck130_provenance.
- NP498674.RAbL4h8X0744Qfo_me5zu2a3hgNxtyZKKB5EeruYA0Z4o130_assertion description "[Other members of the SMAD family are excellent candidates for JPS, especially SMAD2 (which, like SMAD4, is mutated somatically in colorectal cancers), SMAD3 (which causes colorectal cancer when `knocked out` in mice), SMAD5, and SMAD1.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498674.RAbL4h8X0744Qfo_me5zu2a3hgNxtyZKKB5EeruYA0Z4o130_provenance.
- NP498678.RAXTUiyvdEWFs-rsozT_-FTzWvY1lb-jKmZlxYwh8ulFU130_assertion description "[The broad expression of Pirt among dorsal root ganglion neurons suggests it may modulate other transient receptor potentials, such as the menthol and cooling sensor TRPM8.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498678.RAXTUiyvdEWFs-rsozT_-FTzWvY1lb-jKmZlxYwh8ulFU130_provenance.
- NP498679.RAaEudXOKF3UQJrljxnyl4TSdwgaFZ-Lt7ePRNPNADDuA130_assertion description "[These results suggest that LKB1 inactivation in the context of RAS activation facilitates metastasis by inducing an SFK-dependent expansion of a prometastatic, CD24(+) tumor subpopulation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498679.RAaEudXOKF3UQJrljxnyl4TSdwgaFZ-Lt7ePRNPNADDuA130_provenance.
- NP498680.RATxuD5eDgd-JyiYOCaW9okl_NHc1vhoaJamMit0nALTE130_assertion description "[Our results suggest that the leukemia with inv(3)(q21q26) represents a new cytogenetic-clinicopathologic subtype, characterized by 1) abnormal megakaryopoiesis and multiple hematopoietic lineage involvement; 2) an antecedent MDS; 3) poor response to conventional chemotherapy; and 4) expression of CD7, CD34, CD38, HLA-DR, CD13, and CD33 antigens.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498680.RATxuD5eDgd-JyiYOCaW9okl_NHc1vhoaJamMit0nALTE130_provenance.
- NP498681.RAXOMoAatXQSOC0x-NBpOpGRpohW0C4-G7Zs9z2XS4-xY130_assertion description "[This is indicative of MCL, like B-CLL, being derived from naive pre-germinal center B cells and furthermore underscores the postulated relationship of MCLs with the B cells of the normal follicular mantle zone because it has recently been shown that this mantle zone is solely or at least largely composed of naive (nonmutated) B cells.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498681.RAXOMoAatXQSOC0x-NBpOpGRpohW0C4-G7Zs9z2XS4-xY130_provenance.
- NP498683.RAfK3fj3URn9wPwY9Fe0zQwHDMgbgg6LJVrppQfKo--Sw130_assertion description "[Fibrodysplasia ossificans progressiva (FOP; OMIM 135100) is a rare but extremely disabling genetic disorder of the skeletal system, and is characterized by the progressive development of ectopic ossification of skeletal muscles and subsequent joint ankylosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498683.RAfK3fj3URn9wPwY9Fe0zQwHDMgbgg6LJVrppQfKo--Sw130_provenance.
- NP498685.RAXIjJQXjSnoXlPRLo2YNJAFMnqqW5_-PcVv0-AA99Nu0130_assertion description "[Epstein-Barr virus infection in XLP-1 and XLP-2 was the common trigger of HLH (XLP-1, 92%; XLP-2, 83%).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498685.RAXIjJQXjSnoXlPRLo2YNJAFMnqqW5_-PcVv0-AA99Nu0130_provenance.
- NP498688.RAZ0cEElX2_V8XZ-ijTeBjus6pHiW64Ey-MFm_PdvgCJE130_assertion description "[Levels of the prostaglandin D2 synthase (PTGDS) gene, recently associated with the progression of atherosclerosis, were significantly different in the three pairwise comparisons (EAT>MAT>SAT).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498688.RAZ0cEElX2_V8XZ-ijTeBjus6pHiW64Ey-MFm_PdvgCJE130_provenance.
- NP498695.RAToLgty8oGw5mxYdX-Ko7I8FYTfz2SvDD7DZNtF44DAs130_assertion description "[The molecular basis of IHH/KS is reviewed, with particular emphasis on the three most common genes ( KAL1, FGFR1, and GNRHR) that possess mutations in these patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498695.RAToLgty8oGw5mxYdX-Ko7I8FYTfz2SvDD7DZNtF44DAs130_provenance.
- NP498697.RAYTt10HOqojYGRnw9cCEk1hUNkS7jN5Rn4HKyIfYmpWA130_assertion description "[Haploinsufficiency of desmoplakin causes a striate subtype of palmoplantar keratoderma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498697.RAYTt10HOqojYGRnw9cCEk1hUNkS7jN5Rn4HKyIfYmpWA130_provenance.
- NP498708.RAf0reYCybUlvIP3SBNozSveuiLUPfR-KFogWyWGLoKGo130_assertion description "[CYP2C and IL-6 expression in breast cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498708.RAf0reYCybUlvIP3SBNozSveuiLUPfR-KFogWyWGLoKGo130_provenance.
- NP498710.RARnHH3uKcbO8RqcdS7wtTQuXDUHy41p7b6wSAQI3b8so130_assertion description "[The involvement of the serotonin transporter (SERT) and 5-HT(2A) receptor (5-HT(2A)R) in diabetes has also been suggested.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498710.RARnHH3uKcbO8RqcdS7wtTQuXDUHy41p7b6wSAQI3b8so130_provenance.
- NP498716.RAZJhVVJftFFCnpB3SRAkuPpLu2jqdcUsLocw0lI-y_jU130_assertion description "[Mice lacking the gene for TrkA, a receptor tyrosine kinase for NGF, share dramatic phenotypic features of CIPA, including loss of responses to painful stimuli, although anhidrosis is not apparent in these animals.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498716.RAZJhVVJftFFCnpB3SRAkuPpLu2jqdcUsLocw0lI-y_jU130_provenance.
- NP498717.RAUr7d3X-JAmcXWyWAHM9GJUba2xO21k-jCFxbw5Q7Nyo130_assertion description "[Dysregulation of epidermal growth factor and insulin-like growth factor signaling play important roles in human hepatocellular carcinoma (HCC), leading to frequent activation of their downstream targets, the ras/raf/extracellular signal-regulated kinase (ERK) and the phosphoinositide 3-kinase (PI3K)/Akt/mammalian Target of Rapamycin (mTOR) pathways.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498717.RAUr7d3X-JAmcXWyWAHM9GJUba2xO21k-jCFxbw5Q7Nyo130_provenance.
- NP498724.RAUZOhcvZ69Au5RhViMJYW9ZhEuTBA481cKJa6GmFuVDY130_assertion description "[Therefore, blocking CD40 and inhibiting MRP1 are potential targets to treat CD40-induced drug resistance in multiple myeloma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498724.RAUZOhcvZ69Au5RhViMJYW9ZhEuTBA481cKJa6GmFuVDY130_provenance.
- NP498728.RAQne6EZg_yL99BNMF_OxAK6zP1yJ3JXyk1fdSvEtL_3E130_assertion description "[In a specialized ataxia clinic, 54 presymptomatic carriers of SCA2 polyglutamine expansions and 56 relatives without mutation were documented with regard to their maximal saccade velocity (MSV).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498728.RAQne6EZg_yL99BNMF_OxAK6zP1yJ3JXyk1fdSvEtL_3E130_provenance.
- NP498730.RAVvx2RohINtnAUtsfPR2orRgZrVXCmmr8WAciKL79J6o130_assertion description "[Soluble gp130 is up-regulated in the implantation window and shows altered secretion in patients with primary unexplained infertility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498730.RAVvx2RohINtnAUtsfPR2orRgZrVXCmmr8WAciKL79J6o130_provenance.
- NP498731.RAdXktLrCy3t5baYXhvWeHJ6PT7SYS21o885OcGPgenWI130_assertion description "[MYC, ERBB2, and the 11q13 region were amplified in 23, 20, and 21% of breast tumors, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498731.RAdXktLrCy3t5baYXhvWeHJ6PT7SYS21o885OcGPgenWI130_provenance.
- NP498744.RAZSVKprlu9OCmekuhu8uZqdzqbUkCovVjKtGw4K1rPjs130_assertion description "[Dot blot analysis with 11 DNA sequences from this PAI demonstrated that 7 sequences were more prevalent among uropathogens: 2 probes were more prevalent among cystitis and pyelonephritis isolates, 2 among pyelonephritis isolates only, and 3 among cystitis isolates only than among fecal isolates.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498744.RAZSVKprlu9OCmekuhu8uZqdzqbUkCovVjKtGw4K1rPjs130_provenance.
- NP498745.RAep3kDgYqWDCqpFDOM5kOLDmPupc71nDTw2nWe9HQa0w130_assertion description "[To determine the incidence of copy number variants in cancer predisposition genes from families in the Wessex region, we have analysed the hMLH1 and hMSH2 genes in patients with hereditary nonpolyposis colorectal cancer (HNPCC), BRCA1 and BRCA2 in families with hereditary breast/ovarian cancer (BRCA) and APC in patients with familial adenomatous polyposis coli (FAP).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498745.RAep3kDgYqWDCqpFDOM5kOLDmPupc71nDTw2nWe9HQa0w130_provenance.
- NP498749.RAZmwKiHVSYB-SOotT2uKQnCAElf-xI8s3KX7CvEcPp7c130_assertion description "[After a long latency, secondary lesions, such as mutations in the SRSF2 gene, contribute to progression to full-blown malignancy, with abnormal differentiation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498749.RAZmwKiHVSYB-SOotT2uKQnCAElf-xI8s3KX7CvEcPp7c130_provenance.
- NP498753.RARv0vmawzm5bbWn7NQZpi-zbvevO9wI5YaW88iY7USNY130_assertion description "[Mutant ubiquitin and p62 immunoreactivity in cases of combined multiple system atrophy and Alzheimer's disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498753.RARv0vmawzm5bbWn7NQZpi-zbvevO9wI5YaW88iY7USNY130_provenance.
- NP498756.RAXG0qa-8_BrQCM-uZVJTCyZg-beDH5_eXcfCPh9tVD3A130_assertion description "[Both MHC and non-MHC associations have been described and the 8.1 haplotype has been significantly associated with autoimmunity in IgA deficiency patients over controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498756.RAXG0qa-8_BrQCM-uZVJTCyZg-beDH5_eXcfCPh9tVD3A130_provenance.
- NP498757.RAQq67XeYCr5V__pa0I8T1XSlesOmx6-2Lc48kKtYg9c4130_assertion description "[Mutations in genes involved in the control of steroidogenesis, such as NR5A1 (SF-1, Steroidogenic Factor 1), CYP17, CYP19A1 (aromatase), StAR (Steroidogenic Acute Regulatory), and the forkhead transcription factor FOXL2 have been associated with different forms of POI.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498757.RAQq67XeYCr5V__pa0I8T1XSlesOmx6-2Lc48kKtYg9c4130_provenance.
- NP498763.RATz6j4a0n4UwXecgZfLq0pqyIzGRZyukYBbPzhEM8SJs130_assertion description "[As far as lymphocyte subsets were concerned, we found a significant increase in the absolute number of total and activated (CD3+HLA-DR+) T lymphocytes and a significant increase in the absolute number and percentage of suppressor/cytotoxic T lymphocytes (CD8) and NK lymphocytes (CD57) in GDM patients compared with normal pregnant controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498763.RATz6j4a0n4UwXecgZfLq0pqyIzGRZyukYBbPzhEM8SJs130_provenance.
- NP498764.RARA_sNWXh8kByuOWmi2Dbcwy_toHUYesEGBcKoQrotpU130_assertion description "[An increased activation of the renin-angiotensin system probably plays a major role in the development of post-transplant erythrocytosis (PTE).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498764.RARA_sNWXh8kByuOWmi2Dbcwy_toHUYesEGBcKoQrotpU130_provenance.
- NP498769.RAQr9aFifUBPNDIhvuf3XI9cA3NIleMgNjNmehMdTIuqI130_assertion description "[A total of 2,049 individuals (656 Crohn's disease [CD], 544 ulcerative colitis [UC], and 849 controls) were genotyped and association studies were performed for 1 single nucleotide polymorphism (SNP) in MAGI2, 1 SNP in PARD3, and 6 SNPs in MYO9B.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498769.RAQr9aFifUBPNDIhvuf3XI9cA3NIleMgNjNmehMdTIuqI130_provenance.
- NP498772.RAXekA9y0B-Otf785eID7Nr-_f6TBkg2xQpoPr-TyK6Jc130_assertion description "[This study is to investigate the mechanisms by which epidermal growth factor (EGF) regulates NHE1 expression to promote cervical cancer cell invasiveness and the clinical significance in early-stage cervical cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498772.RAXekA9y0B-Otf785eID7Nr-_f6TBkg2xQpoPr-TyK6Jc130_provenance.
- NP498773.RAdrp1ubaE5T3SSGJOpLqj-OAgj0wH7wiw0m-cGOdqBdg130_assertion description "[p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498773.RAdrp1ubaE5T3SSGJOpLqj-OAgj0wH7wiw0m-cGOdqBdg130_provenance.
- NP498776.RAfjx7ivyQbuwzoMKjA2GcOjnt5mghmiJhoJJuj-l79cs130_assertion description "[To investigate whether endothelial cells become activated during tumorigenesis and progression of human gliomas by a platelet-derived growth factor (PDGF) dependent pathway, we analyzed platelet-derived growth factor receptor-beta (PDGFR-beta) expression by in situ hybridization and immunocytochemistry in normal human brain, astrocytoma (grade II), anaplastic oligo-astrocytoma (grade III), and glioblastoma multiforme (grade IV).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498776.RAfjx7ivyQbuwzoMKjA2GcOjnt5mghmiJhoJJuj-l79cs130_provenance.
- NP498780.RAVK9dt2PFISJ_uQ1nNecYcrYuFhyQt7V8mTsqXUlpO1I130_assertion description "[The results reveal that synergy between the Wnt and mitogen-activated protein (MAP) kinase pathways may represent an important mechanism underpinning the genesis of melanoma, a highly aggressive and increasingly common disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498780.RAVK9dt2PFISJ_uQ1nNecYcrYuFhyQt7V8mTsqXUlpO1I130_provenance.
- NP498782.RAdzETxkckNkSAaFF6a_qmyGquK-suhLarRakSfxuwYRs130_assertion description "[Synthesis of PAI-2 and transcription of its mRNA could be induced by a protein kinase C (PKC) activator, phorbol myristate acetate.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498782.RAdzETxkckNkSAaFF6a_qmyGquK-suhLarRakSfxuwYRs130_provenance.
- NP498789.RAUecFb0dXFqNse0BXwy1q-faSUtV5XJ8DXPLA8rvTgE4130_assertion description "[Ovarian cancer has frequent loss of heterozygosity at chromosome 12p12.3-13.1 (region of TEL and Kip1 loci) and chromosome 12q23-ter: evidence for two new tumour-suppressor genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498789.RAUecFb0dXFqNse0BXwy1q-faSUtV5XJ8DXPLA8rvTgE4130_provenance.
- NP498793.RAUwv_N3QHGU2Gz6xyXilVeRq-9qDaFbEOIQpboHWZy7c130_assertion description "[Having a high IGF-I/IGFBP-3 ratio was associated with increased persistence of oncogenic HPV infection [that is, a lower rate of clearance; adjusted hazard ratio (AHR), 0.14; 95% confidence interval (95% CI), 0.04-0.57], whereas IGFBP-3 was inversely associated with both the incident detection of oncogenic HPV (AHR, 0.35; 95% CI, 0.13-0.93) and the incidence of oncogenic HPV-positive cervical neoplasia (that is, squamous intraepithelial lesions at risk of progression; AHR, 0.07; 95% CI, 0.01-0.66).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498793.RAUwv_N3QHGU2Gz6xyXilVeRq-9qDaFbEOIQpboHWZy7c130_provenance.
- NP498795.RAVAqHXGSJ9Yq6u3JLcW33wlE6yqKAvq2enFBNyEFTc1I130_assertion description "[The MCP-1 receptor, CCR2, was overexpressed in the glomerular podocytes of patients with overt nephropathy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498795.RAVAqHXGSJ9Yq6u3JLcW33wlE6yqKAvq2enFBNyEFTc1I130_provenance.
- NP498803.RAUyNAkPYeuqzfINUV8o5zkoKuyPJXefEeo7bZXxsk09o130_assertion description "[One FAOD, L-3-hydroxyacyl-CoA dehydrogenase (LCHAD) deficiency has been associated with liver disease in pregnancies involving a heterozygous mother carrying an affected fetus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498803.RAUyNAkPYeuqzfINUV8o5zkoKuyPJXefEeo7bZXxsk09o130_provenance.
- NP498827.RAS9ZM3urW0lW1WrP7EQc_CcK4UoxVHZ9lzA_b6TSCL5c130_assertion description "[First-degree relatives of persons with type 1 diabetes: insulin resistance and enterovirus infection are associated with different patterns of islet cell autoimmunity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498827.RAS9ZM3urW0lW1WrP7EQc_CcK4UoxVHZ9lzA_b6TSCL5c130_provenance.
- NP498831.RAXNbrIqS34yDXUvflOFGn3FDeMGkyS2Sf-oyVgswsXvI130_assertion description "[The HLA haplotype DRB1*15-DPB1*05 can be a susceptibility gene marker for the development of TDI-induced asthma among the exposed workers in the Korean population.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498831.RAXNbrIqS34yDXUvflOFGn3FDeMGkyS2Sf-oyVgswsXvI130_provenance.
- NP498833.RAe8heSFljbC1x1Q1K1lwKv6k0r9nTwlUSwuF9fh3mw5o130_assertion description "[Missense mutations in the sodium borate cotransporter SLC4A11 cause late-onset Fuchs corneal dystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498833.RAe8heSFljbC1x1Q1K1lwKv6k0r9nTwlUSwuF9fh3mw5o130_provenance.
- NP498834.RAcVhcCCTAvYoPioZ70Lnpgw99SOwg1hnyHBp7tjgJ2nc130_assertion description "[Our results show that array CGH is a useful tool for identification of gene alteration in lung cancer, and that the above-mentioned genes might represent potential candidate genes for pathogenesis and diagnosis of lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498834.RAcVhcCCTAvYoPioZ70Lnpgw99SOwg1hnyHBp7tjgJ2nc130_provenance.
- NP498838.RAdCCWo9HSaxYxjD4YOaHrXhm1Xy_zpuYBnE8qU01FaP8130_assertion description "[Mutations in the AFG3L2 gene have been linked to spinocerebellar ataxia type 28 and spastic ataxia-neuropathy syndrome in humans; however, the pathogenic mechanism is still unclear.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498838.RAdCCWo9HSaxYxjD4YOaHrXhm1Xy_zpuYBnE8qU01FaP8130_provenance.
- NP498841.RAVEajtUGIhNOvcU-Htr0_ayQz9FbZM7YXoeJFyOwJG9E130_assertion description "[Here we explored the use of an intercomplementing anthrax toxin that requires combined cell surface uPA and MMP activities for cellular intoxication and specifically targets the ERK/MAPK pathway for the treatment of HNSCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498841.RAVEajtUGIhNOvcU-Htr0_ayQz9FbZM7YXoeJFyOwJG9E130_provenance.
- NP498852.RAelFaRI83XD18bgvSw_tO5RhPL4Pc0m3FZ3RmNiZzRqg130_assertion description "[Percutaneous coronary intervention (PCI) has become an effective therapy to treat obstructive coronary artery diseases (CAD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498852.RAelFaRI83XD18bgvSw_tO5RhPL4Pc0m3FZ3RmNiZzRqg130_provenance.
- NP498863.RATCXJiai-ckzqycnXmgLDPzz6TNMSVORTEshVFd4QGpM130_assertion description "[Although BLK has been reproducibly identified as a risk factor in rheumatoid arthritis (RA), reports are conflicting about the contribution of BANK1 to RA susceptibility.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498863.RATCXJiai-ckzqycnXmgLDPzz6TNMSVORTEshVFd4QGpM130_provenance.
- NP498866.RAQkx-GJE-IZVlAoOT87cPsrS8sQ_826N-Ca57pF-720A130_assertion description "[To study the mechanism of interleukin-6 (IL-6) induction of human C-reactive protein (CRP) gene expression, we have utilized a human hepatoma (PLC/PRF/5) cell culture system to analyze the trans-acting factors which bind to the 300 bp 5'-flanking region of human CRP gene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498866.RAQkx-GJE-IZVlAoOT87cPsrS8sQ_826N-Ca57pF-720A130_provenance.
- NP498868.RAWQYGwUQMeFuHTs0hqKRz6Ok29sEvvKpOb_NSYyJr6NY130_assertion description "[Thus, in this retroviral gene transfer model, NPM-ALK expression in mice causes B-lineage large-cell lymphoma, suggesting a direct causative role for this activated fusion tyrosine kinase in human lymphoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498868.RAWQYGwUQMeFuHTs0hqKRz6Ok29sEvvKpOb_NSYyJr6NY130_provenance.
- NP498869.RAdMKJ9qSsMosBpGDWi7cqtfDJe7I76gI21yviaGjgobw130_assertion description "[Human genetic studies have now shown that 25-30% of patients have hereditary PH due to a germline mutation in the SDHB, SDHD, VHL, RET or NF1 gene and that the identification of a germline SDHB mutation is associated with a high risk of malignancy and a poor prognosis in PH/PGL patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498869.RAdMKJ9qSsMosBpGDWi7cqtfDJe7I76gI21yviaGjgobw130_provenance.
- NP498870.RAXurR_7BOpfFHY9rnR1VzXX1ooCAHGI7Ih8rKati3hHU130_assertion description "[Hyaluronic acid and HYAL1-type hyaluronidase show high accuracy in detecting bladder cancer and evaluating its grade, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498870.RAXurR_7BOpfFHY9rnR1VzXX1ooCAHGI7Ih8rKati3hHU130_provenance.
- NP498871.RAbbPLAxhC10bK5JI5dnY2aMUHgsIRmh-b0cdxRW8cMXo130_assertion description "[Immunoblotting results showed that activated PKR (pPKR) and activated eIF2α (peIF2α) and BACE1 levels are increased in AD cortices and BACE1 correlate with phosphorylated eIF2α levels.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498871.RAbbPLAxhC10bK5JI5dnY2aMUHgsIRmh-b0cdxRW8cMXo130_provenance.
- NP498873.RAcozm1Xv5M8dQ2dKGS60uG6zY23RzTB-v7bxpgwQhK3Q130_assertion description "[We address the ways in which aggregated α-SYN mediates toxicity and might lead to PD, and propose possible therapeutic strategies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498873.RAcozm1Xv5M8dQ2dKGS60uG6zY23RzTB-v7bxpgwQhK3Q130_provenance.
- NP498882.RAX6x52YuBKsbES9KBezdUU9LV-00OsOwRPUnea-owcS4130_assertion description "[In preliminary studies, intermittent infusions of interleukin-2 led to increases in CD4 counts in patients with human immunodeficiency virus (HIV) infection and more than 200 CD4 cells per cubic millimeter.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498882.RAX6x52YuBKsbES9KBezdUU9LV-00OsOwRPUnea-owcS4130_provenance.
- NP498887.RAXE3IEWL4zbVpSaquyJUcvxphRou-sV-Heg0mXp1CmxQ130_assertion description "[How stromelysin-1 5A/6A polymorphism affects ISR appears to be linked to angina status.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498887.RAXE3IEWL4zbVpSaquyJUcvxphRou-sV-Heg0mXp1CmxQ130_provenance.
- NP498889.RAW_8DbTN_aq-7y5PZOI3gVISsCmB33pD2xSgQFB65LQI130_assertion description "[We also examined the 1p36 (CAPB) region in 13 PRCA families with at least one case of brain cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498889.RAW_8DbTN_aq-7y5PZOI3gVISsCmB33pD2xSgQFB65LQI130_provenance.
- NP498892.RATviuZWjr-P4bfXV_UXUXzKsEwPQduXAsqzrSEyEsU6E130_assertion description "[The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498892.RATviuZWjr-P4bfXV_UXUXzKsEwPQduXAsqzrSEyEsU6E130_provenance.
- NP498894.RAfr7uS8H0DaxTipoY9RhydK0jN_zrblAiQCGeiPWezvI130_assertion description "[High levels of type I PKA occur in primary breast carcinomas and patients exhibiting this phenotype show decreased survival.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498894.RAfr7uS8H0DaxTipoY9RhydK0jN_zrblAiQCGeiPWezvI130_provenance.
- NP498895.RAUU0aS2MDii631XcslEul5fpPfVlzowyTKQxaMljU2Ko130_assertion description "[After adenomectomy the hypokalemia and hypertension were resolved, and the plasma ACTH, cortisol, and PRA remained within the reference ranges.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498895.RAUU0aS2MDii631XcslEul5fpPfVlzowyTKQxaMljU2Ko130_provenance.
- NP498897.RAbCQARKgctqEsOkwgivB7QUIYeGI5fMz-ZhIrc3QbcnM130_assertion description "[Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498897.RAbCQARKgctqEsOkwgivB7QUIYeGI5fMz-ZhIrc3QbcnM130_provenance.
- NP498905.RAXG0q7gl-AreH1LJeo_8xKLN8DC5bKAxVT-hCQ-S2aew130_assertion description "[We aimed at evaluating the role of those MSH5 polymorphisms on IgAD susceptibility considering their linkage with other classically associated HLA markers, specifically DRB1*0102 and B*08-DRB1*03.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498905.RAXG0q7gl-AreH1LJeo_8xKLN8DC5bKAxVT-hCQ-S2aew130_provenance.
- NP498911.RAR0b8V3MXq0mSqkG9PjZW2dr2xJLNXUzgWsdoKSj-POk130_assertion description "[The chromosomal translocation t(12;21) (p12;q22) which results in the TEL-AML1 fusion gene is the most frequent genetic rearrangement in childhood B-lineage acute lymphoblastic leukemia (ALL).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498911.RAR0b8V3MXq0mSqkG9PjZW2dr2xJLNXUzgWsdoKSj-POk130_provenance.
- NP498914.RAXIVw7YLrjwLl239YoQf6UU9822YH8VsX6LYQi0LFrK0130_assertion description "[No X-linked AS cases are due to COL4A6 mutations, but all DL/AS cases are always associated with deletions spanning the 5' regions of the COL4A5/COL4A6 cluster.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498914.RAXIVw7YLrjwLl239YoQf6UU9822YH8VsX6LYQi0LFrK0130_provenance.
- NP498922.RAYoBfaH73o3w6QcGjKg8VpurQW8Ay__jBtetWAF3nHG8130_assertion description "[Using an in vitro assay, we further show that non-Smad signaling pathways, including p38 and c-Jun NH(2)-terminal kinase, cooperate with TGF-beta/Smads in enhancing migration of metastatic MCF10CA1a cells, but that, although necessary for migration, these other pathways are not sufficient for metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498922.RAYoBfaH73o3w6QcGjKg8VpurQW8Ay__jBtetWAF3nHG8130_provenance.
- NP498930.RAdsCvGQCAp7r6Z6xNp-2vTMcGbRSzWNKRnJSURJBxMxg130_assertion description "[Among the genes disrupted by the remaining rare CNVs are MYT1L, CTNND2, NRXN1, and ASTN2, genes that play an important role in neuronal functioning but--except for NRXN1--have not been associated with schizophrenia before.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498930.RAdsCvGQCAp7r6Z6xNp-2vTMcGbRSzWNKRnJSURJBxMxg130_provenance.
- NP498937.RAXa_rJKSmqylEyFtJk0YeNKPpWhLUlNp1Qopm95W17a8130_assertion description "[Mir-17-5p and mir-20a, members of the mir-17-92 family, down-regulate E2F1, which is over-expressed in myelodysplastic syndromes (MDS).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498937.RAXa_rJKSmqylEyFtJk0YeNKPpWhLUlNp1Qopm95W17a8130_provenance.
- NP498938.RASN7HtTOHYJSD56lSnT1xBPrOWg0sVKz38fpL3wVwW1s130_assertion description "[Influence of killer cell immunoglobulin-like receptor genotypes on acute graft-vs-host disease after unrelated hematopoietic stem cell transplantation in Koreans.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498938.RASN7HtTOHYJSD56lSnT1xBPrOWg0sVKz38fpL3wVwW1s130_provenance.
- NP498941.RAQg4dxm_stzr656GUZhuP6efrTpXESwUsntnEPQoRfAk130_assertion description "[Familial amyloidotic polyneuropathy (FAP) is an autosomal dominant genetic disease, and the major component of the amyloid fibrils from FAP patients was shown to be variants of transthyretin (TTR) with single amino acid substitutions.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498941.RAQg4dxm_stzr656GUZhuP6efrTpXESwUsntnEPQoRfAk130_provenance.
- NP498943.RAWt14Mly37SkhPzfMzKpKIDZL84AVw8-4Zv1gYzDYxfI130_assertion description "[Only the second compound heterozygous IGF1R mutations to be identified, the p.E121K/E234K variant is the cause of intrauterine growth retardation and the most severe postnatal growth failure described to date in a patient with IGF1R defects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498943.RAWt14Mly37SkhPzfMzKpKIDZL84AVw8-4Zv1gYzDYxfI130_provenance.
- NP498944.RAVelrZ3JfFg95vqRzFleamxbzaiX1GWbTOH_TZ1shPns130_assertion description "[Primary hyperparathyroidism (PHP; serum calcium 2.75 mmol/L, PTH 226 pg/ml) had been the first clinical manifestation of MEN-2A in a female patient (aged 55 years) with a mutation (Y791F, TAT-->TTT) in exon 13 of the RET proto-oncogene.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498944.RAVelrZ3JfFg95vqRzFleamxbzaiX1GWbTOH_TZ1shPns130_provenance.
- NP498949.RAQ527ni90LPSn7lccccAPY5BK1WNe-ck3BPJdlic2Ix4130_assertion description "[Here we report the characterization, at the genomic level and at the cDNA level, of both the MCCA gene and the MCCB gene, encoding the MCC alpha and MCC beta subunits, respectively.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498949.RAQ527ni90LPSn7lccccAPY5BK1WNe-ck3BPJdlic2Ix4130_provenance.