Matches in Nanopublications for { ?s <http://purl.org/dc/terms/description> ?o ?g. }
- NP498962.RARrBG-yWZr2Jfy79YUCmkBOXTdqJP7Qkt4IEPqC1yljw130_assertion description "[p38 activation by both adenovirus-mediated gene delivery of constitutively active p38 activator MKK6 and by arsenite selectively induces cell death in K-ras-activated human colon cancer HCT116 cells but not in the K-ras-disrupted HCT116-derived sublines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498962.RARrBG-yWZr2Jfy79YUCmkBOXTdqJP7Qkt4IEPqC1yljw130_provenance.
- NP498974.RAeP9aOA3VEfSp6pMyPJ7iTqk8Upr205JiSuO5FB2eUDU130_assertion description "[Insulin-like growth factor binding protein 2 (IGFBP-2) has been implicated in the pathophysiology of neoplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498974.RAeP9aOA3VEfSp6pMyPJ7iTqk8Upr205JiSuO5FB2eUDU130_provenance.
- NP498975.RAedwOgfADeF4zjiEeBqAP0gubJEMFGDowqW9XOdviFFY130_assertion description "[While the proband did not have the classic features of CFC, he had some dysmorphic craniofacial characteristics, ectodermal anomalies and moderate developmental delay which were suggestive of CFC syndrome; however, this patient did not have classical CFC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498975.RAedwOgfADeF4zjiEeBqAP0gubJEMFGDowqW9XOdviFFY130_provenance.
- NP498976.RAXzMbQ0WylOMlcP2ZCCVCRDygJ3wRrlOTiK0bTJa3z4E130_assertion description "[We analyzed the whole mitochondrial genome from seven PTC and three FTC tumors along with the corresponding normal thyroid tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498976.RAXzMbQ0WylOMlcP2ZCCVCRDygJ3wRrlOTiK0bTJa3z4E130_provenance.
- NP498977.RAYqWaSe5-ufogaaDsiUqmc_dRw_iXpuzyAE1zoRUDIMA130_assertion description "[Inactivating mutations of the LHR cause Leydig cell hypoplasia (LCH) in males while that of the FSHR causes hereditary hypergonadotropic ovarian dysgenesis (ODG) in females.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498977.RAYqWaSe5-ufogaaDsiUqmc_dRw_iXpuzyAE1zoRUDIMA130_provenance.
- NP498979.RAW6UfV7Vp9Ky8lo0YzT1Sd2sM1Q6t_nrQrW5NUdMjfIc130_assertion description "[The characterization of epsilon-sarcoglycan should make it possible to determine if it, like the other sarcoglycan genes, is mutated in muscular dystrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498979.RAW6UfV7Vp9Ky8lo0YzT1Sd2sM1Q6t_nrQrW5NUdMjfIc130_provenance.
- NP498982.RATduOCoHBqUkF8Q68BWJ2icO3d4_TKwHKxQgb0Fm-IQc130_assertion description "[PPAR-gamma agonist Azelaoyl PAF increases both messenger RNA and protein levels of frataxin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498982.RATduOCoHBqUkF8Q68BWJ2icO3d4_TKwHKxQgb0Fm-IQc130_provenance.
- NP498985.RAStTqP8Tm5X6HG6iH-aaWtIwWDpfYwol6P3r70xNpuio130_assertion description "[Microscopic agglutination test (MAT), as well as other serological assays that aimed at detecting antibodies to Leptospira, supplements the leptospirosis diagnosis based on the clinical features.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498985.RAStTqP8Tm5X6HG6iH-aaWtIwWDpfYwol6P3r70xNpuio130_provenance.
- NP498989.RAfeEvnFHcPyHkRkAKyK5YeBbS9HDI1eFTnz-ldY9gngU130_assertion description "[To study the controversial role of cytomegalovirus (CMV) in glioblastoma, we assessed the effects of murine CMV (MCMV) perinatal infection in a GFAP-cre; Nf1(loxP/+); Trp53(-/+) genetic mouse model of glioma (Mut3 mice).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498989.RAfeEvnFHcPyHkRkAKyK5YeBbS9HDI1eFTnz-ldY9gngU130_provenance.
- NP498990.RAWh4cL4C1BaLkwZ1bkw9CXr7se94lp1XYH-x6cS9av2E130_assertion description "[MED12, the mediator complex subunit 12 gene, has been recently implicated as an oncogene in as many as 70% of sporadic uterine leiomyoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498990.RAWh4cL4C1BaLkwZ1bkw9CXr7se94lp1XYH-x6cS9av2E130_provenance.
- NP498993.RAcsxQub9gAGJEk6gudqMiYGxmwbLb7EbCevBzuEoiyzs130_assertion description "[Immunophenotypic analysis of reticulocytes in peripheral blood of patients with PNH demonstrated the conserved patterns of DAF and CD59 expression in circulating erythroid cells and the discrepancies between granulocytic and erythroid lineages.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498993.RAcsxQub9gAGJEk6gudqMiYGxmwbLb7EbCevBzuEoiyzs130_provenance.
- NP498994.RAYiF3RczQ62fAYPFzVbrp6Eq6y_OTyb2YkJ0hZcO_1jY130_assertion description "[The role of the calcium binding protein, Calbindin 2 (CALB2), in regulating the response of colorectal cancer (CRC) cells to 5-Fluorouracil (5-FU) was investigated.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP498994.RAYiF3RczQ62fAYPFzVbrp6Eq6y_OTyb2YkJ0hZcO_1jY130_provenance.
- NP499004.RAXfPCJm1shKt-49LuoxKUO0UZPF_q-xc_9NKiED4MjaM130_assertion description "[To determine the association between polymorphisms of the multidrug transporter genes ABCC2, ABCC5 and ABCG2, and drug resistance in epilepsy by genotyping comprehensive sets of tagging SNPs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499004.RAXfPCJm1shKt-49LuoxKUO0UZPF_q-xc_9NKiED4MjaM130_provenance.
- NP499006.RAfi0jNbqNdehggXwbba8PmDyr9n_t0hYbDTKW_0KdymQ130_assertion description "[Genetic heterogeneity evidenced by low incidence of KAL-1 gene mutations in sporadic cases of gonadotropin-releasing hormone deficiency.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499006.RAfi0jNbqNdehggXwbba8PmDyr9n_t0hYbDTKW_0KdymQ130_provenance.
- NP499011.RAVtCwdvUuvKl9EldzG5l0aS-UNmpQ6nBcK6TUhNVVssA130_assertion description "[We reported previously that MPS-1 was highly expressed in human gastric cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499011.RAVtCwdvUuvKl9EldzG5l0aS-UNmpQ6nBcK6TUhNVVssA130_provenance.
- NP499016.RAf3ypra1EOQNLjrU8DiCNR1sDr4tMjH0y5pgtr7F5h2A130_assertion description "[Because other studies have implicated the MMP family in promoting tumor metastasis, we investigated the apparently paradoxical expression of MMP-8 in these cell lines.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499016.RAf3ypra1EOQNLjrU8DiCNR1sDr4tMjH0y5pgtr7F5h2A130_provenance.
- NP499019.RAXUgF1hUauiC_ZSrzpafiezLC6hkZCIFEkI7QPxLVQsg130_assertion description "[This new paradigm places EMP centrally in the process of tumour progression and metastasis, as well as modulating drug response to current forms of chemotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499019.RAXUgF1hUauiC_ZSrzpafiezLC6hkZCIFEkI7QPxLVQsg130_provenance.
- NP499020.RAbuiQN8KEmG1E9gTBSv0Fn4zkNWOWB2UE3Eupsus9XQY130_assertion description "[TSP-1 immunohistochemistry was performed in the eyes of human donors (8 normal and 17 with glaucoma).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499020.RAbuiQN8KEmG1E9gTBSv0Fn4zkNWOWB2UE3Eupsus9XQY130_provenance.
- NP499022.RAR1AIdYEJTCtH5C1DZcz9zXsOznoCyPa1XXxp0v2z_NY130_assertion description "[Pemphigus vulgaris (PV) and pemphigus foliaceus (PF), in which autoantibodies bind, respectively, to desmoglein 3 and desmoglein 1, are strongly associated with HLA-class II DR4 and DR14 alleles.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499022.RAR1AIdYEJTCtH5C1DZcz9zXsOznoCyPa1XXxp0v2z_NY130_provenance.
- NP499025.RARf9IzirQ9Ltjv8T7qzE7FKcg7ooLcKCQGciXY9kjawY130_assertion description "[We have capitalized on the susceptibility of p53+/- mice to chronic, low dose, aromatic amine-induced bladder carcinogenesis to develop a useful model for evaluating bladder cancer prevention approaches such as cyclooxygenase-2 inhibition.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499025.RARf9IzirQ9Ltjv8T7qzE7FKcg7ooLcKCQGciXY9kjawY130_provenance.
- NP499026.RAS0fFrhH5P5GjUbP09ZtVKsdn3FNSmcFvotCsny1BySM130_assertion description "[Archipelago (AGO, also known as hCdc4, Fbw7, or Sel-10) is an F-box containing component of the SCF complex implicated in the ubiquitination and proteolysis of cyclin E and c-Myc, and found to be mutated in 16% of endometrial carcinomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499026.RAS0fFrhH5P5GjUbP09ZtVKsdn3FNSmcFvotCsny1BySM130_provenance.
- NP499028.RAQBPHjolYFkMPL2kVTEuWpS1H9rYdWML23m9TaMOD4L8130_assertion description "[We have analyzed common risk variants within RD (MRPL19/C2ORF3, KIAA0319, and DCDC2) and language impairment (CMIP and ATP2C2) candidate loci in the Avon Longitudinal Study of Parents and Children cohort (n = 3725), representing children born in southwest England in the early 1990s.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499028.RAQBPHjolYFkMPL2kVTEuWpS1H9rYdWML23m9TaMOD4L8130_provenance.
- NP499032.RAd4jesc7wscYLgboFe0M2PhSyLlWtV0kwnqul3vCWJPk130_assertion description "[No statistical difference was found in IL-23 mRNA expression or plasma IL-22, IL-17 levels among E-MDS, L-MDS and controls.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499032.RAd4jesc7wscYLgboFe0M2PhSyLlWtV0kwnqul3vCWJPk130_provenance.
- NP499034.RAWQkYCPEk6JLRJv9BV31ApBiBx8F_wpXtghEooikNtdE130_assertion description "[Characteristics of small bowel carcinoma in hereditary nonpolyposis colorectal carcinoma. International Collaborative Group on HNPCC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499034.RAWQkYCPEk6JLRJv9BV31ApBiBx8F_wpXtghEooikNtdE130_provenance.
- NP499035.RAeTnp2aeAEqD-KdEgv9Ie9agtjCejsoqqMpl-LpyocpQ130_assertion description "[Genetics of focal segmental glomerulosclerosis and human immunodeficiency virus-associated collapsing glomerulopathy: the role of MYH9 genetic variation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499035.RAeTnp2aeAEqD-KdEgv9Ie9agtjCejsoqqMpl-LpyocpQ130_provenance.
- NP499036.RAXGAIXXB4DpSDqukAVlsT-7UVrt2JCIAYddp-7WQoQuc130_assertion description "[Our results showed that compared with uninfected control mice, hepatic NKT cells from HBV transgenic mice displayed lower frequencies (7.91% vs 16.74%, P < 0.05), impaired capabilities to produce interferon (IFN)-γ (5.6% vs 1.4%, P < 0.05) and interleukin (IL)-4 (6.8% vs 0.3%, P < 0.05), higher expression of PD-1 (9.64% vs 6.36%, P < 0.05) and lower expression of CD28 (5.05% vs 28.88%, P < 0.05).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499036.RAXGAIXXB4DpSDqukAVlsT-7UVrt2JCIAYddp-7WQoQuc130_provenance.
- NP499037.RAYhH2jaYZ10fTbXfXF24K6loojobSEDDayFL8sWAmHCM130_assertion description "[To examine the role of alpha-1,3-fucosyltransferase in the synthesis of sialyl Lewis x and the prognosis of lung cancer, PCR amplification of five fucosyltransferase genes and immunohistochemical staining of sialyl Lewis x were performed in 333 patients with lung cancer who underwent surgical resection from 1980 to 1993.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499037.RAYhH2jaYZ10fTbXfXF24K6loojobSEDDayFL8sWAmHCM130_provenance.
- NP499042.RAa8EH9_MRYQI1L1sPtflZYUWZ_B_LeyhboE2i6O8hseI130_assertion description "[Study of the molecular basis of HMPS will enhance our knowledge of the genetic basis of the mixed polyposis-carcinoma sequence in both hereditary and sporadic CRC.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499042.RAa8EH9_MRYQI1L1sPtflZYUWZ_B_LeyhboE2i6O8hseI130_provenance.
- NP499047.RAS1l_nR_zjbMYCSsa2OYy2PUhjHrulfy7ELAoHPI1RnQ130_assertion description "[The mapping of the human tuftelin gene to a well-defined cytogenetic region could be important in understanding the etiology of autosomally inherited amelogenesis imperfecta, the most common hereditary disease of enamel.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499047.RAS1l_nR_zjbMYCSsa2OYy2PUhjHrulfy7ELAoHPI1RnQ130_provenance.
- NP499049.RAaZTWUZtjlo5UXaQC-7f9Q7YRFv1i9KnvSkTkkcP3oIo130_assertion description "[Distant recurrence remains the major cause of mortality in rectal cancer patients with preoperative chemoradiotherapy (CRT).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499049.RAaZTWUZtjlo5UXaQC-7f9Q7YRFv1i9KnvSkTkkcP3oIo130_provenance.
- NP499050.RAfmpfjdS2WoJWQKGX3MO6b0yMQ3Ouw6xHbK7pCxaoV6s130_assertion description "[HSP70-hom gene polymorphism in allogeneic hematopoietic stem-cell transplant recipients correlates with the development of acute graft-versus-host disease.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499050.RAfmpfjdS2WoJWQKGX3MO6b0yMQ3Ouw6xHbK7pCxaoV6s130_provenance.
- NP499055.RAYfpq6PbFiM4gAJ77EXx6ZH019k8UN4XeyrQTy13yVdM130_assertion description "[In conclusion, we were unable to confirm previously reported associations between the DRD3 BalI polymorphism and psychotic symptoms in AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499055.RAYfpq6PbFiM4gAJ77EXx6ZH019k8UN4XeyrQTy13yVdM130_provenance.
- NP499057.RAfbZ7OcJOIUrMdwLBOW9tXi_dWmAEAaXQlxl27RnaTK8130_assertion description "[Two genomewide association studies of predominantly sporadic but also familial cases of TGCT have implicated the KIT-ligand, SPRY4, and BAK1 genes as TGCT risk modifiers.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499057.RAfbZ7OcJOIUrMdwLBOW9tXi_dWmAEAaXQlxl27RnaTK8130_provenance.
- NP499063.RAQ7rxQkjfMb0FMZEe5263dIknErBn9uESE8xW833YoE0130_assertion description "[The defect in the type II OI patient affected residue 211 of the alpha 1(I) triple helical domain, and constitutes the most amino-terminal lethal glycine-->arginine substitution described to date.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499063.RAQ7rxQkjfMb0FMZEe5263dIknErBn9uESE8xW833YoE0130_provenance.
- NP499065.RAQVdxwePbJLUJS5DmHGR3fo2YFOrRhWZm1bfjkYbbKmw130_assertion description "[Two genes were associated with asthma in the entire sample before correction (CAT and NQO1) and one was associated after correction for multiple analyses (CAT).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499065.RAQVdxwePbJLUJS5DmHGR3fo2YFOrRhWZm1bfjkYbbKmw130_provenance.
- NP499068.RAeF1yXGHMvUs1BF2gP86ypT_sIkJjHAtHmYei2sC4Lnw130_assertion description "[Renal tumour subtype/nephron segment-specific gene expression detected by RQ-PCR demonstrated that the tumour expressed relatively high amounts of alpha-methylacyl-CoA racemase (AMACR) and the KIT oncogene, but relatively low amounts of carbonic anhydrase IX (CA9), aquaporin 1 (AQP1), claudin 7 (CLDN7), parvalbumin (PVALB), chloride channel Kb (CLCNKB) and 11-beta-hydroxysteroid dehydrogenase 2 (HSD11B2), suggesting diverse mRNA signatures.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499068.RAeF1yXGHMvUs1BF2gP86ypT_sIkJjHAtHmYei2sC4Lnw130_provenance.
- NP499074.RAdd1UB-ci43ZJqPJH-CCHC7DKbQVQTrFqoOpT1yCT09g130_assertion description "[The level of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in the lung cell suspension was also raised considerably following treatment with SP-D or rhSP-D. Our results appear to reaffirm the notion that under immunocompromised conditions, human SP-D or its truncated form can offer therapeutic protection against fatal challenge with Afu conidia challenge.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499074.RAdd1UB-ci43ZJqPJH-CCHC7DKbQVQTrFqoOpT1yCT09g130_provenance.
- NP499081.RAUvukPTX2E3oYes5WzOtJ7skZjsxLq4HH_yhGMmNkCpo130_assertion description "[We examined 10 surgically obtained sacral chordoma tissue samples to determine the expressions of NGF and TrkA and p75 receptors as well as markers of cellular proliferation and apoptosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499081.RAUvukPTX2E3oYes5WzOtJ7skZjsxLq4HH_yhGMmNkCpo130_provenance.
- NP499092.RASE70PPomCOCRhv7dGxTeeuydrzy6GCmxgSektx95fR4130_assertion description "[Global association with haplotypes comprising all four markers at IFNGR1 (chi(2)(10df)=21.97, P=0.015) was observed, associated with a significant (chi(2)(1df)=4.54, P=0.033) bias in transmission of the haplotype insTT T T T and less (chi(2)(1df)=5.59, P=0.018) than expected transmission of insTT C C C. When compared with data on malaria associations from Gambia, the results suggest a complex pattern of haplotypic variation at the IFNGR1 promoter locus associated with different infectious disease in African populations that reflect the complex roles of IFN-gamma in parasite killing versus inflammation and pathogenesis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499092.RASE70PPomCOCRhv7dGxTeeuydrzy6GCmxgSektx95fR4130_provenance.
- NP499094.RAdqRIAVibxsjO-xM9jP56aIlBhoQvJgv8KYnoNlQSo24130_assertion description "[The current study indicates that: (i) there are statistical differences between patients with double curve, with Cobb angle ≥ 40° and with thoracic curve and healthy controls in the polymorphic distribution of the rs2234693 site of the ER1 gene, (P= 0.014, 0.0128, 0.0184 respectively); (ii) there is a difference between patients with double curve and controls in the polymorphic distribution of the rs12885713 site in the CALM1 gene (P= 0.034); and (iii) there is a difference between thoracic curve patients and controls in the polymorphic distribution of the rs5871 site in the CALM1 gene (P= 0.0102).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499094.RAdqRIAVibxsjO-xM9jP56aIlBhoQvJgv8KYnoNlQSo24130_provenance.
- NP499099.RAV2cDp5ma7XzrfzdiJ96bKqsm3bTDWIdtYoCtAux7ZhI130_assertion description "[In this study, as we determined p53 gene mutation occurring in multinucleated giant cell glioblastoma, we investigated the role of Aurora-B in formation of multinucleated cells in human neoplasm cells with various p53 statuses as well as cytotoxity of glioma cells to temozolomide (TMZ), a common oral alkylating agent used in the treatment of gliomas.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499099.RAV2cDp5ma7XzrfzdiJ96bKqsm3bTDWIdtYoCtAux7ZhI130_provenance.
- NP499108.RAVwA5qDG2R8LvkoTsKj1soqozMtDGdi6l1SQarsDp_fI130_assertion description "[In murine models of autoimmune lupus, mutations in cell death receptor Fas (CD95) and its ligand, FasL (CD95 L), have been identified.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499108.RAVwA5qDG2R8LvkoTsKj1soqozMtDGdi6l1SQarsDp_fI130_provenance.
- NP499109.RAZM1V6RFWztDigCfqDxJ5mwSz2jrJnPJ32GuP8YpGLjM130_assertion description "[Coding polymorphisms in Casp5, Casp8 and DR4 genes may play a role in predisposition to lung cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499109.RAZM1V6RFWztDigCfqDxJ5mwSz2jrJnPJ32GuP8YpGLjM130_provenance.
- NP499111.RAdZR119Kog7Fw2Rv-YdYHnEZrHBBfqLm_rvNZoMcQ9NU130_assertion description "[Identification of a novel exon 4 SOD1 mutation in a sporadic amyotrophic lateral sclerosis patient.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499111.RAdZR119Kog7Fw2Rv-YdYHnEZrHBBfqLm_rvNZoMcQ9NU130_provenance.
- NP499112.RAQsWJ3hlUM0KNhcD9cA_j4WepdTGDOSEoqvtQqXin6kQ130_assertion description "[We found that in a mouse model of the human lysosomal storage disease GM1-gangliosidosis, GM1-ganglioside accumulates in the glycosphingolipid-enriched microdomain (GEM) fractions of MAMs, where it interacts with the phosphorylated form of IP3 receptor-1, influencing the activity of this channel.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499112.RAQsWJ3hlUM0KNhcD9cA_j4WepdTGDOSEoqvtQqXin6kQ130_provenance.
- NP499116.RAXpY4887we86Msvq3DT0ZNyEimTY3ouR5yblNzVJN_XQ130_assertion description "[This hypothesis has been provoked by the identification of loss of heterozygosity (LOH) at the M6P/IGF2R locus on chromosome 6q26 in breast and liver cancer, accompanied by point mutations in the remaining allele.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499116.RAXpY4887we86Msvq3DT0ZNyEimTY3ouR5yblNzVJN_XQ130_provenance.
- NP499117.RAVLolxPHpmd_oYezL5S8TJw_n-eruK4LOkcqxDIBh0QA130_assertion description "[Besides `typical HGPS,` several `atypical progeria` syndromes (APS) have been described, in a clinical spectrum ranging from mandibuloacral dysplasia to atypical Werner syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499117.RAVLolxPHpmd_oYezL5S8TJw_n-eruK4LOkcqxDIBh0QA130_provenance.
- NP499119.RAQe9yAsxwgsAF1eUyo2SXVAaf80W9L608brap4BlPsIs130_assertion description "[Narcolepsy is associated with polymorphisms of the genes encoding T cell receptor alpha chain, tumour necrosis factor alpha and tumour necrosis factor receptor II.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499119.RAQe9yAsxwgsAF1eUyo2SXVAaf80W9L608brap4BlPsIs130_provenance.
- NP499127.RAY7FllfFvc2mbHXUH9JObQ7TnZwS0h1BwCbSimyQiXLo130_assertion description "[Mutations in the NHEJ factor ARTEMIS cause radiation-sensitive severe combined immunodeficiency in humans and may increase susceptibility to lymphoma in some settings.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499127.RAY7FllfFvc2mbHXUH9JObQ7TnZwS0h1BwCbSimyQiXLo130_provenance.
- NP499130.RAXuNkYXHxivs02JcWa5qJO1RhWc-QdvB1Xt74svN2tNE130_assertion description "[Genetic defects in ISBT may result in malabsorption of bile acids and a loss of bile acids into the large intestine, with a resultant increase in the cytotoxic secondary bile acids in the colon.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499130.RAXuNkYXHxivs02JcWa5qJO1RhWc-QdvB1Xt74svN2tNE130_provenance.
- NP499131.RAS1pYGUMTzeq596giGIs1uKvldpBnn-aR4yEmJKaLAhc130_assertion description "[LAP1 and LAP2 may prove to be functionally independent promoter elements that control 2-kb LAT expression during different stages of HSV-1 infections.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499131.RAS1pYGUMTzeq596giGIs1uKvldpBnn-aR4yEmJKaLAhc130_provenance.
- NP499134.RAUwNAQvlUumEXq52kAYNQMOesa1a-Nwp2Gqnt6-f28uc130_assertion description "[FISH was performed on paraffin-embedded tissue from 40 histologically unequivocal melanocytic tumours (10 metastatic melanomas, 10 primary melanomas and 20 benign melanocytic naevi) using the product Vysis LSI RREB1/LSI MYB/LSI CCND1/CEP 6 probes (Abbott Molecular Laboratories, USA), which is designed to detect the copy number of the RREB1 (6p25), MYB (6q23), and CCND1 (11q13) genes and FISH positivity is defined by means of a scoring algorithm.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499134.RAUwNAQvlUumEXq52kAYNQMOesa1a-Nwp2Gqnt6-f28uc130_provenance.
- NP499135.RAWh-rN9vRsamVMSb9-w3wHaxq6VDqFEMGmzfNlXKeypg130_assertion description "[Both monocyte chemoattractant protein-1 (MCP-1), a member of chemokine family, and angiotensinogen, a precursor of angiotensin (ANG) II, are produced by adipose tissue and increased in obese state.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499135.RAWh-rN9vRsamVMSb9-w3wHaxq6VDqFEMGmzfNlXKeypg130_provenance.
- NP499136.RASeyyarEyDPsaja3mFDvvTWVUjRGyzXYTW-zYNC6t2yI130_assertion description "[CD14+CD33+ myeloid cell-CCL11-eosinophil signature in ulcerative colitis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499136.RASeyyarEyDPsaja3mFDvvTWVUjRGyzXYTW-zYNC6t2yI130_provenance.
- NP499142.RATs-pZzTwGzJrCywppj9v6QOsqIwfQd81iOoyhX8gOAQ130_assertion description "[The duplication 17p11.2 syndrome, associated with dup(17)(p11.2p11.2), is a recently recognized syndrome of multiple congenital anomalies and mental retardation and is the first predicted reciprocal microduplication syndrome described--the homologous recombination reciprocal of the Smith-Magenis syndrome (SMS) microdeletion (del(17)(p11.2p11.2)).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499142.RATs-pZzTwGzJrCywppj9v6QOsqIwfQd81iOoyhX8gOAQ130_provenance.
- NP499145.RAdCWWfSDeXq5WYvOrOnni9I-_OKp9Gf1QOxdDKxBswjI130_assertion description "[These results suggest that increased HTLV-1 proviral DNA loading may play an important role in the development of T lymphocyte alveolitis and myelopathy in patients with HAM/TSP.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499145.RAdCWWfSDeXq5WYvOrOnni9I-_OKp9Gf1QOxdDKxBswjI130_provenance.
- NP499146.RAUi_wCofl-syPu1_P6l8XDrZuWgB4T7zGSarTmjU4vvU130_assertion description "[These results confirm that TPO is expressed in thyroid carcinomas but in smaller amounts than in normal tissue and benign tumors.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499146.RAUi_wCofl-syPu1_P6l8XDrZuWgB4T7zGSarTmjU4vvU130_provenance.
- NP499149.RAQXdXG6xU3h-22gJL_NTY442DWASZIpa-lUFfu5q37yc130_assertion description "[However, our study indicates that a fraction of sporadic LAM can be a TSC1 disease; therefore, both TSC genes should be examined, even for patients with sporadic LAM.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499149.RAQXdXG6xU3h-22gJL_NTY442DWASZIpa-lUFfu5q37yc130_provenance.
- NP499155.RAV1Cvuny0dnaz1UAaAx4mGd422TSa1tmxr7A3aYGiVuc130_assertion description "[The percentages of CD19- and CD20-positive cells in MALT lymphoma tissue from the patients in remission were both significantly lower than those in the tissue from patients not in remission.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499155.RAV1Cvuny0dnaz1UAaAx4mGd422TSa1tmxr7A3aYGiVuc130_provenance.
- NP499159.RAavZKZXnMIMkLyxrHkbAfUbn88qjvnlmwjJDHVz0UGa8130_assertion description "[Cerebral arterial stenoses and stroke: novel features of Aicardi-Goutières syndrome caused by the Arg164X mutation in SAMHD1 are associated with altered cytokine expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499159.RAavZKZXnMIMkLyxrHkbAfUbn88qjvnlmwjJDHVz0UGa8130_provenance.
- NP499160.RAagRekG2xFOrJVFH-f9T8_xFWjgzpxEmNNa-1VC0WCT4130_assertion description "[This study was the first to suggest a possible role of gene expression analysis of ANK3, RASGRP1 and POLG1 in the LCLs as potential biomarkers of BD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499160.RAagRekG2xFOrJVFH-f9T8_xFWjgzpxEmNNa-1VC0WCT4130_provenance.
- NP499164.RAWVQHjh9TTqxJEC1waXKHMQ-hMcpeGP6Mj28Tlcgy7Iw130_assertion description "[Translocations involving the immunoglobulin heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499164.RAWVQHjh9TTqxJEC1waXKHMQ-hMcpeGP6Mj28Tlcgy7Iw130_provenance.
- NP499170.RARE7BfeP8V_ZyTf42BXQ9hW45chJefvFkGxSkLdeAMw0130_assertion description "[Mutations in genes that encode RET ligands (GDNF and NTN); components of another signaling pathway (EDNRB, EDN3, ECE-1); and the transcription factor, SOX10, have been identified in HSCR patients.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499170.RARE7BfeP8V_ZyTf42BXQ9hW45chJefvFkGxSkLdeAMw0130_provenance.
- NP499173.RAWvruZEO3eJQFfiPi3nqf5zED5-y1osHh2JkqQ0qGl_c130_assertion description "[These findings confirm previous studies that aneusomy of 7 is associated with prostate cancer progression, and there may be a tumor suppressor gene (TSG) at 7q31.1 which is associated with tumor progression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499173.RAWvruZEO3eJQFfiPi3nqf5zED5-y1osHh2JkqQ0qGl_c130_provenance.
- NP499175.RAQiM1g8yFiZ8XFGX5Ikv_l6NSEDfdjd68zDa8hlCgMdU130_assertion description "[Type I hyperlipoproteinemia (type I HLP) is a rare disorder of lipid metabolism characterized by fasting chylomicronemia and reduced postheparin plasma lipoprotein lipase (LPL) activity.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499175.RAQiM1g8yFiZ8XFGX5Ikv_l6NSEDfdjd68zDa8hlCgMdU130_provenance.
- NP499176.RAS-njdPYTPkMfKbQNoGOK00JPRQRx31bnijsRXh09HAQ130_assertion description "[Using denaturing high-performance liquid chromatography and DNA sequencing, mutational analysis of 23 RyR2 exons previously implicated in CPVT1, comprehensive analysis of all translated exons in CASQ2 (CPVT2), KCNQ1 (LQT1), KCNH2 (LQT2), SCN5A (LQT3), KCNE1 (LQT5), KCNE2 (LQT6), and KCNJ2 (Andersen-Tawil syndrome [ATS1], also annotated LQT7), and analysis of 10 ANK2 exons implicated in LQT4 were performed on genomic DNA from 11 unrelated patients (8 females) referred to Mayo Clinic's Sudden Death Genomics Laboratory explicitly for CPVT genetic testing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499176.RAS-njdPYTPkMfKbQNoGOK00JPRQRx31bnijsRXh09HAQ130_provenance.
- NP499180.RAcIf9ghYKA7tPI-P5ZF0XsTRHtyzTGayc0YMe46BaJRI130_assertion description "[We analyzed the GJB2 and SLC26A4 genes for the presence of mutations, screened for the mitochondrial DNA (mtDNA) A1555G mutation, and screened for congenital CMV infection in DNA isolated from dried newborn blood spots.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499180.RAcIf9ghYKA7tPI-P5ZF0XsTRHtyzTGayc0YMe46BaJRI130_provenance.
- NP499190.RARJ3IqVGDIO3NKkgrYZhTJICcIqDS_a-YnzsGAK9vAOo130_assertion description "[Antibody raised against the L2-I/beta-Gal protein in a rabbit reacted with viral antigens in the nuclei of cells in superficial epithelium of the condyloma acuminatum tissue, but did not react with the antigens in the bovine papilloma tissue.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499190.RARJ3IqVGDIO3NKkgrYZhTJICcIqDS_a-YnzsGAK9vAOo130_provenance.
- NP499193.RAbYei_EPL4cy8HEN3uko-FOjksbK_7wUqY-LTPvVF3L4130_assertion description "[mRNA levels of CENP-A and CENP-B, a centromere protein that binds independently of CENP-A, were measured in breast cancer specimens from 484 patients receiving no systemic therapy, 276 patients receiving tamoxifen, and 233 patients treated with neoadjuvant chemotherapy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499193.RAbYei_EPL4cy8HEN3uko-FOjksbK_7wUqY-LTPvVF3L4130_provenance.
- NP499202.RAdBAutO-yp6h7RGObfvpOJkWZ3e0tm6yp1aWaVndO0WI130_assertion description "[However, in the periodontitis group, a 24-year-old individual from Ghana with localized juvenile periodontitis was identified with an intraoral infection with highly toxic A. actinomycetemcomitans (JP2-like).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499202.RAdBAutO-yp6h7RGObfvpOJkWZ3e0tm6yp1aWaVndO0WI130_provenance.
- NP499207.RAf_gVvMxBRQe_P6YoFDsi1q15WjEsBL6jYIDbQ4FoJrs130_assertion description "[Plasmatherapy does not appear to influence the outcome of aHUS with membrane cofactor protein mutation, and its efficacy in patients with factor I, C3, or factor B mutations is suggested by a few reports.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499207.RAf_gVvMxBRQe_P6YoFDsi1q15WjEsBL6jYIDbQ4FoJrs130_provenance.
- NP499214.RARx3x2HA53bSFLRBR9mo8Cc9d4OKCsqHlHiQh4e3Fu1k130_assertion description "[Opioids regulate CREB level, its phosphorylation and binding to its corresponding response element in the promoters of several genes implicated in drug addiction.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499214.RARx3x2HA53bSFLRBR9mo8Cc9d4OKCsqHlHiQh4e3Fu1k130_provenance.
- NP499218.RAQcs4gNW1ggKG5R43MCGndnlk6AG9cUvQ0nxNwVu1YjY130_assertion description "[The polymorphism of the immunoglobulin heavy chain switch region gene in IgA nephropathy, Henoch-Schönlein nephritis and idiopathic nephrotic syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499218.RAQcs4gNW1ggKG5R43MCGndnlk6AG9cUvQ0nxNwVu1YjY130_provenance.
- NP499219.RASOlWQ-yFIh62qbOknmqJIFCwD_JZOj7qs7cSAGiscOs130_assertion description "[Mutation of PACRG was not identified as a cause of male infertility, but variation in the promoter was demonstrated to be a risk factor associated with azoospermia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499219.RASOlWQ-yFIh62qbOknmqJIFCwD_JZOj7qs7cSAGiscOs130_provenance.
- NP499220.RAQLmwPeNbbXKrlHZXRtERHw5KOYeazIITToDjzvN9IV0130_assertion description "[Unlike PNH cells, 6-TG-resistant cells expressed CD59, indicating that the HPRT mutations did not occur in PNH clones.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499220.RAQLmwPeNbbXKrlHZXRtERHw5KOYeazIITToDjzvN9IV0130_provenance.
- NP499222.RAYNFlCTviRVviXpc12jf4MpWWI-JQrAQeIsMGQTt1m1Q130_assertion description "[Gaucher disease is a lysosomal storage disease resulting from a defect in the enzyme acid β-glucosidase 1. β-glucosidase 2 is an enzyme with similar glucosylceramidase activity but to date has not been associated with a monogenic disorder.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499222.RAYNFlCTviRVviXpc12jf4MpWWI-JQrAQeIsMGQTt1m1Q130_provenance.
- NP499224.RAR0ISEb-tNDzWF89jluAnn-xOEF1ecOM0FEzBs4wvyZM130_assertion description "[Chromosomal translocations in individuals with both syndromes had localized an autosomal sex reversal locus (SRA1) and a campomelic dysplasia locus (CMPD1) to the long arm of human chromosome 17.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499224.RAR0ISEb-tNDzWF89jluAnn-xOEF1ecOM0FEzBs4wvyZM130_provenance.
- NP499235.RAfbIokQeHTaFSCcBRsDj_5iKFQbaP_kFchYG67xIFBZk130_assertion description "[The implications of our results are discussed in light of the HLA-DR4-associated susceptibility to insulin autoimmune syndrome and HLA-DR9-associated susceptibility to juvenile-onset myasthenia gravis and systemic lupus erythematosus with antiphospholipid syndrome, in particular T cell responses to autoantigens.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499235.RAfbIokQeHTaFSCcBRsDj_5iKFQbaP_kFchYG67xIFBZk130_provenance.
- NP499236.RAacAp8IPIygbjfBnMY7ttPGom9LAPy5pmb0X12Fvg0Ps130_assertion description "[Similarly, we found that haplotype B which carried LMP7 and TAP1-2 variations significantly increased the susceptibility to TB (OR = 3.674, 95% CI: 2.254-5.988; P<0.0001).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499236.RAacAp8IPIygbjfBnMY7ttPGom9LAPy5pmb0X12Fvg0Ps130_provenance.
- NP499242.RAc7TlJqEq5T1nKfZj1gEeTntMUL_CP3hAVctxhS9tggw130_assertion description "[Initially identified as a serological marker for advanced squamous cell carcinomas of the cervix, SCCA1 has also been found to be associated with other cancer types of epithelial or endodermal origins such as lung cancer, head and neck cancer, melanoma, and hepatocellular carcinoma.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499242.RAc7TlJqEq5T1nKfZj1gEeTntMUL_CP3hAVctxhS9tggw130_provenance.
- NP499249.RAYip08yRGyceQg9HK_l50bo9xJSEfAo-Hgg7co-BmnY4130_assertion description "[Human CMV (HCMV)-encoded NK cell-evasion functions include an MHC class I homolog (UL18) with high affinity for the leukocyte inhibitory receptor-1 (CD85j, ILT2, or LILRB1) and a signal peptide (SP(UL40)) that acts by upregulating cell surface expression of HLA-E.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499249.RAYip08yRGyceQg9HK_l50bo9xJSEfAo-Hgg7co-BmnY4130_provenance.
- NP499251.RAX5N5wOGtm453HgTaG3agouBOFN1LhRKEyW3aU6AqK34130_assertion description "[ABO blood group alleles: A risk factor for coronary artery disease. An angiographic study.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499251.RAX5N5wOGtm453HgTaG3agouBOFN1LhRKEyW3aU6AqK34130_provenance.
- NP499253.RAcXxE9PLqi7h1NTMq_DhSViPpjy3d_dsR5DyYwMIiCvY130_assertion description "[Comprehensive mutational analysis of the 5 LQTS-causing channel genes, KCNQ1 (LQT1), KCNH2 (LQT2), SCN5A (LQT3), KCNE1 (LQT5), and KCNE2 (LQT6), along with KCNJ2 (Andersen-Tawil syndrome) and targeted analysis of 18 CPVT1-associated exons in RyR2, was performed with the use of denaturing high-performance liquid chromatography and direct DNA sequencing.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499253.RAcXxE9PLqi7h1NTMq_DhSViPpjy3d_dsR5DyYwMIiCvY130_provenance.
- NP499255.RAeytoiEAykYDdRM7IEEFroOk5Y8_WXZr8Ui72wfuRGOU130_assertion description "[Both SOX4 and SOX11 were significantly overexpressed in medulloblastoma (median, 11-fold and 5-fold, respectively) compared with ependymoma and normal cerebellum.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499255.RAeytoiEAykYDdRM7IEEFroOk5Y8_WXZr8Ui72wfuRGOU130_provenance.
- NP499256.RAX7P_M4TTRxU8ywdnyeH23s0FOW4DdkHorxh6ePvoQGg130_assertion description "[Using this new assay we could demonstrate that the majority of OPA1 mutations that lead to a premature termination codon (PTC) undergo nonsense-mediated mRNA decay (NMD).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499256.RAX7P_M4TTRxU8ywdnyeH23s0FOW4DdkHorxh6ePvoQGg130_provenance.
- NP499264.RAcYuL7XQNGXBqWlAUl2sPtcmuu_dGVmklNhCIKQ3gF9Q130_assertion description "[Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499264.RAcYuL7XQNGXBqWlAUl2sPtcmuu_dGVmklNhCIKQ3gF9Q130_provenance.
- NP499274.RAYaOHVuBOH7bWOKOax8QCxRh4LhTyrU_NNKBbioK3mx4130_assertion description "[We have previously shown that ezrin is regulated by androgen in rat prostate and that its expression is increased in prostate cancer and in prostate intraepithelial neoplasia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499274.RAYaOHVuBOH7bWOKOax8QCxRh4LhTyrU_NNKBbioK3mx4130_provenance.
- NP499277.RAXUxvcrrwj3WsiVJb6c5ZH0APIVHsCJS3vUekYe9bWZ8130_assertion description "[AD-ADMD is characterized by early contractures of elbows and Achilles tendons and a humero-peroneal distribution of weakness combined with a cardiomyopathy with conduction defects.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499277.RAXUxvcrrwj3WsiVJb6c5ZH0APIVHsCJS3vUekYe9bWZ8130_provenance.
- NP499278.RAdSQqYvXA9jUV15C6_KqRMBTXgAwHgNwuHrETjhUCCfI130_assertion description "[A pathological hallmark of both sporadic and familial ALS is the presence of abnormal accumulations of neurofilament and peripherin proteins in motor neurons.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499278.RAdSQqYvXA9jUV15C6_KqRMBTXgAwHgNwuHrETjhUCCfI130_provenance.
- NP499281.RAUcNrRPSv7W6c-Qq9xq8KjoO5AwIYh5eVUk_xQmGWVOo130_assertion description "[We compared multilayer perceptron (MLP) and logistic regression (LR) analysis for predicting prostate cancer in a screening population of 974 men, ages 55-66 years.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499281.RAUcNrRPSv7W6c-Qq9xq8KjoO5AwIYh5eVUk_xQmGWVOo130_provenance.
- NP499283.RAWw5qegdhgbZX-n4dVu63iKJx3t704XybyrTM19tYa18130_assertion description "[Detailed clinical description showed that all four individuals with a GATAD2B aberration had a distinctive phenotype with childhood hypotonia, severe intellectual disability, limited speech, tubular shaped nose with broad nasal tip, short philtrum, sparse hair and strabismus.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499283.RAWw5qegdhgbZX-n4dVu63iKJx3t704XybyrTM19tYa18130_provenance.
- NP499287.RAb-Ad_x4FRHF8NNKcg0jxJkirWqnmLpXUNbOs8BqiBJM130_assertion description "[We studied the relationships among DNA methyltransferase (DNMT) genotype, DNA methylation, Gleason score, and mortality in two cohorts of prostate cancer patients, previously reported with associations between DNA methylation in GSTP1, APC, and RUNX3 and prostate cancer mortality.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499287.RAb-Ad_x4FRHF8NNKcg0jxJkirWqnmLpXUNbOs8BqiBJM130_provenance.
- NP499289.RAeJHMOmRKLT9S7RiXoeucTWwU5pBzAW2WmjlHk2__UR8130_assertion description "[The lack of the alpha6 chain does not obviously result in disease, in particular leiomyomatosis, as is seen in Alport patients with deletions involving the COL4A5 and COL4A6 genes.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499289.RAeJHMOmRKLT9S7RiXoeucTWwU5pBzAW2WmjlHk2__UR8130_provenance.
- NP499299.RASySzqc6CCWWWCrgpJD4VqQPhXmoGIp0DL2hQQqsHy2c130_assertion description "[Melanoma tumor antigen p97 or melanotransferrin (MTf) is an iron (Fe)-binding protein with high homology to serum transferrin.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499299.RASySzqc6CCWWWCrgpJD4VqQPhXmoGIp0DL2hQQqsHy2c130_provenance.
- NP499300.RAW7xz40XhFBglpM3urVApoj13zPzGbJYH-nxE7sc1b0E130_assertion description "[In addition to their different clonal origin, Reed-Sternberg cells of Hodgkin's disease expressed a CD15+, CD20+ (rare cells), CD30+, Oct-2-, EBNA2-, LMP1+ phenotype, whereas anaplastic and Reed-Sternberg-like cells of diffuse large B-cell lymphoma were CD15-, CD20+, CD30+, Oct-2+, EBNA2+, and LMP1+.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499300.RAW7xz40XhFBglpM3urVApoj13zPzGbJYH-nxE7sc1b0E130_provenance.
- NP499303.RATtCAcWiDZLlqNmLkyeQj480w-lMJ5FafsMbNcV6Bgpk130_assertion description "[Mutations in the gene SURF1 prevent synthesis of cytochrome-c oxidase (COX)-specific assembly protein and result in a fatal neurological disorder, Leigh syndrome.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499303.RATtCAcWiDZLlqNmLkyeQj480w-lMJ5FafsMbNcV6Bgpk130_provenance.
- NP499305.RAbUUhMdAPcabL4724_ROGarduFPN-P5Vjm-raGAvzPQc130_assertion description "[p300 and CBP are implicated in regulation of ER-β activity and cellular migration in prostate cancer.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499305.RAbUUhMdAPcabL4724_ROGarduFPN-P5Vjm-raGAvzPQc130_provenance.
- NP499311.RAcwLzLCr7x-2Uq-MtNocmb7SJj214Rfi8DXG2HH8ikGE130_assertion description "[This study provides a pathogenetic psoriasis model using a psoriasis candidate gene to link the epidermis and innate immune system in inflammation priming, highlighting the S100A7A15-RAGE axis as a potential therapeutic target.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499311.RAcwLzLCr7x-2Uq-MtNocmb7SJj214Rfi8DXG2HH8ikGE130_provenance.
- NP499312.RAfYD7vA7zdZCNZynwIOjsylzbFOiFoJIkNLtjXUmNVZU130_assertion description "[FEV, adenylate cyclase 2 (ADCY2), nuclear receptor subfamily 4, group A, member 2 (NR4A2), and growth arrest and DNA-damage-inducible, beta (GADD45b) were the most highly up-regulated genes in the malignant group of PNETs.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499312.RAfYD7vA7zdZCNZynwIOjsylzbFOiFoJIkNLtjXUmNVZU130_provenance.
- NP499322.RAQAKBkFY2gyh3tBJpPf952dPS_lKD3SsREgtGKvAwkEo130_assertion description "[Microarray analysis demonstrated that HM-3 at high dose could up-regulate the transcription of AKT1 and MEK1, which resulted in the promotion of tumorigenesis and metastasis.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP499322.RAQAKBkFY2gyh3tBJpPf952dPS_lKD3SsREgtGKvAwkEo130_provenance.