Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence Inhibition+of+NOX5+activity+reduces+spermatozoa+motility. assertion.
- assertion asSentence SMAC+negatively+regulates+the+anti-apoptotic+activity+of+melanoma+inhibitor+of+apoptosis+%28ML-IAP%29. assertion.
- assertion asSentence ULBP3+binds+to+the+NGK2D+receptor+and+activates+multiple+signaling+pathways+in+primary+natural+killer+cells. assertion.
- assertion asSentence ULBPs+and+MICA+are+expressed+in+lipid+rafts+at+the+cell+surface+of+NK+and+T+cells. assertion.
- assertion asSentence Mutations+in+HRPT2+is+associated+with+Hyperparathyroidism+Jaw-tumor+syndrome. assertion.
- assertion asSentence Mutations+in+HRPT2+is+associated+with+Hyperparathyroidism+Jaw-tumor+syndrome. assertion.
- assertion asSentence Mutation+of+HRPT2+is+associated+with+the+formation+of+parathyroid+tumors+in+hyperparathyroidism-jaw+tumor+syndrome. assertion.
- assertion asSentence HRPT2+inactivation+is+not+an+important+participant+in+the+pathogenesis+of+typical+parathyroid+adenomas. assertion.
- assertion asSentence A+non-consensus+%28non-canonical%29+donor+splice+site+within+exon+1+of+the+HRPT2+gene+is+associated+with+familial+isolated+primary+hyperparathyroidism+%28FIHP%29. assertion.
- assertion asSentence Loss+of+HRPT2+gene+expression+is+strongly+associated+with+parathyroid+carcinomas. assertion.
- assertion asSentence Positive+staining+for+PGP9.5+has+utility+as+a+marker+for+parathyroid+malignancy%2C+with+a+slightly+superior+sensitivity+%28P+%3D+0.03%29+and+similar+high+specificity+to+that+of+parafibromin. assertion.
- assertion asSentence Endogenous+GRAIL+regulates+general+cell+cycle+and+proliferation+of+primary+naive+CD4+T+cells. assertion.
- assertion asSentence Mutations+in+Tctn1+is+associated+with+ciliopathies. assertion.
- assertion asSentence In+patients+with+chronic+hepatitis+c%2C+adiponectin+and+receptors%28AdipoR1+and+AdipoR2%29play+a+role+in+hepatic+inflammation+in+both+sexes+and+liver+steatosis+in+males. assertion.
- assertion asSentence Upregulated+in+insulin-resistant+women+with+polycystic+ovary+syndrome. assertion.
- assertion asSentence Mutations+in+the+ric-3+gene+affect+maturation+of+nicotinic+acetylcholine+receptors. assertion.
- assertion asSentence The+RIC-3e+protein+is+functionally+active+and+enables+surface+expression+of+mature+alpha7-nAChRs+in+cell+lines+not+otherwise+permissive+for+the+expression+of+this+receptor. assertion.
- assertion asSentence Higher+HMGB1%28homeobox+containing+1%29+levels+in+Tracheal+aspirates+are+associated+with+the+development+of+bronchopulmonary+dysplasia+or+death+in+ventilated+premature+infants. assertion.
- assertion asSentence HMBOX1+negatively+regulates+the+expression+of+NKG2D+and+the+activation+of+the+NKG2D%2FDAP10+signaling+pathway+in+NK+cells. assertion.
- assertion asSentence Mistargeting+of+SH3TC2+away+from+the+recycling+endosome+is+the+fundamental+molecular+defect+that+leads+to+Charcot-Marie-Tooth+disease+type+4C. assertion.
- assertion asSentence Compared+with+other+BRCT+domain+structures%2C+the+most+striking+differences+are+an+elongated%2C+ordered+beta1-alpha1+loop+and+an+adjacent+hydrophobic+pocket. assertion.
- assertion asSentence In+the+Australian+GWAS%2C+one+SNP+achieved+genomewide+significance+%28p+%3C+5+x+10%28-8%29%29+for+ND+%28rs964170+in+ARHGAP10+on+chromosome+4%2C+p+%3D+4.43+x+10%28-8%29%29. assertion.
- assertion asSentence Pyrimidine+dimer+repair+enzyme+located+on+the+long+arm+of+chromosome+15+that+is+frequently+deleted+in+human+cancers. assertion.
- assertion asSentence The+ability+of+Neil1+to+recognize+a+variety+of+pyrimidine+lesions+is+connected+to+the+flexible+binding+pocket+of+the+enzyme+and+the+common+chemical+features+of+lesions+that+contain+a+pyrimidine+ring. assertion.
- assertion asSentence B7-H4+directly+promotes+malignant+transformation+of+ovarian+cancer+cell+line. assertion.
- assertion asSentence Plk1+self-regulates+the+Plk1-PBIP1+interaction+to+timely+localize+to+the+kinetochores+and+promote+proper+chromosome+segregation. assertion.
- assertion asSentence Human+WAT+STAMP2+associates+with+obesity+and+insulin+resistance+independently+of+adiponectin. assertion.
- assertion asSentence The+knockdown+of+STEAP4+inhibits+insulin-stimulated+glucose+transport+and+GLUT4+translocation+via+the+attenuated+phosphorylation+of+Akt%2C+independent+of+the+effects+of+EEA1. assertion.
- assertion asSentence Association+of+variants+in+MANEA+with+cocaine+related+behavior+is+established. assertion.
- assertion asSentence Inherited+deleterious+variants+in+GALNT12+are+associated+with+CRC+susceptibility. assertion.
- assertion asSentence LRRK1+genes+encode+low+levels+of+expressed+mRNA+corresponding+to+low+levels+of+protein+during+development. assertion.
- assertion asSentence Importins+4+and+7+accomplish+nuclear+import+of+HIF-1alpha+more+efficiently+than+the+classical+importin+alpha%2Fbeta+NLS+receptor. assertion.
- assertion asSentence Lin28+mRNA+contains+ARE+within+its+3%27-UTR+and+TTP+enhances+the+decay+of+Lin28+mRNA+through+binding+to+its+3%27-UTR. assertion.
- assertion asSentence High+expression+of+Lin28+is+associated+with+poor+prognosis+and+high+tumour+aggressiveness+in+oesophageal+cancer+and+these+effects+are+mediated+through+increased+proliferation+and+invasiveness+of+oesophageal+cancer+cells. assertion.
- assertion asSentence BRCA2+and+PALB2+are+main+regulators+of+G2+checkpoint+maintenance+following+DNA-damage. assertion.
- assertion asSentence Smad-binding+peptide+aptamers+can+be+developed+to+selectively+inhibit+TGF-beta-induced+gene+expression. assertion.
- assertion asSentence ZNF750+directly+links+a+tissue-specifying+factor%2C+p63%2C+to+an+effector+of+terminal+differentiation%2C+KLF4. assertion.
- assertion asSentence MDM2+mediates+formation+of+p53-SUV39H1%2FEHMT1+complex+capable+of+methylating+H3-K9+in+vitro+and+on+p53+target+promoters+in+vivo. assertion.
- assertion asSentence Disruption+of+an+EHMT1-associated+chromatin-modification+module+causes+intellectual+disability. assertion.
- assertion asSentence Calmodulin+methyltransferase+is+an+evolutionarily+conserved+enzyme+that+trimethylates+Lys-115+in+calmodulin. assertion.
- assertion asSentence ASAM%2C+IGSF11%2C+CXADR+and+ESAM+are+type+I+transmembrane+proteins+and+members+of+the+same+IGSF+superfamily. assertion.
- assertion asSentence Gemin6+is+a+component+of+the+SMN+complex+that+localizes+to+gems+and+interacts+with+several+Sm+proteins+of+the+spliceosomal+snRNPs. assertion.
- assertion asSentence Taken+together%2C+CSPP+and+CSPP-L+interact+with+centrosomes+and+microtubules+and+can+differently+affect+microtubule+organization. assertion.
- assertion asSentence Regulation+of+NHE3+depends+on+the+nature+of+the+NHERF+family+member+associating+with+NHE3+and+the+accompanying+NHE3+complexes. assertion.
- assertion asSentence NEK11+regulates+CDC25A+degradation+and+the+IR-induced+G2%2FM+checkpoint. assertion.
- assertion asSentence CEBPA+mutation+status+and+BAALC+expression+are+important+prognostic+factors+in+acute+myeloid+leukemia+patients+with+normal+cytogenetics. assertion.
- assertion asSentence A+high+MEBE+%28MN1%2CERG%2C+BAALC%2C+EVI1%29+expression+score+is+an+unfavorable+prognostic+marker+in+Myelodysplastic+syndrome+and+is+associated+with+an+increased+risk+for+progression+to+Acute+myeloid+leukemia. assertion.
- assertion asSentence Hakai+dimerization+allows+the+formation+of+a+phosphotyrosine-binding+pocket+that+recognizes+specific+phosphorylated+tyrosines+and+flanking+acidic+amino+acids+of+Src+substrates%2C+such+as+E-cadherin%2C+cortactin+and+DOK1. assertion.
- assertion asSentence UBE1DC1+greatly+activated+SUMO2+in+the+nucleus+or+transferred+activated-SUMO2+to+nucleus+after+it+conjugated+SUMO2+in+the+cytoplasm. assertion.
- assertion asSentence ASAP+stabilizes+p53+both+by+alleviating+MDM2-mediated+p53+ubiquitination+and+by+enhancing+its+p300-dependent+acetylation. assertion.
- assertion asSentence The+CD2+domain+of+Nanog+is+a+unique+transactivator+that+utilizes+aromatic+residues+to+confer+specific+activity+absolutely+required+for+ES+self-renewal. assertion.
- assertion asSentence NANOG+regulates+S-phase+entry+in+human+embryonic+stem+cells+%28hESCs%29+via+transcriptional+regulation+of+cell+cycle+regulatory+components. assertion.
- assertion asSentence Downstream+effectors+of+Hedgehog+activity%2C+Gli1+and+Gli2%2C+bind+to+Nanog-specific+cis-regulatory+sequences+both+in+mouse+and+human+stem+cells. assertion.
- assertion asSentence A+variant+in+DHDDS+is+associated+with+retinitis+pigmentosa. assertion.
- assertion asSentence PDZD7+is+a+modifier+of+retinal+disease+and+a+contributor+to+digenic+Usher+syndrome. assertion.
- assertion asSentence The+ciliary+protein+nephrocystin-4+translocates+the+canonical+Wnt+regulator+Jade-1+to+the+nucleus+to+negatively+regulate+beta-catenin+signaling. assertion.
- assertion asSentence Mutations+in+DENND2D+in+melanoma+by+inhibition+of+nonsense-mediated+mRNA+decay. assertion.
- assertion asSentence HsMis13+phosphorylation+by+Aurora+B+is+required+for+organizing+a+stable+bi-oriented+microtubule+kinetochore+attachment+that+is+essential+for+faithful+chromosome+segregation+in+mitosis. assertion.
- assertion asSentence ESRP1+and+ESRP2+are+epithelial+cell-type-specific+regulators+of+FGFR2+splicing. assertion.
- assertion asSentence ESRP2+coordinates+a+complex+alternative+splicing+network+that+adds+an+important+post-transcriptional+layer+to+the+changes+in+gene+expression+that+underlie+epithelial-mesenchymal+transitions+during+development+and+disease. assertion.
- assertion asSentence Pantothenate+kinase-associated+neurodegeneration+is+an+autosomal-recessive+disorder+associated+with+the+accumulation+of+iron+in+the+basal+ganglia+associated+with+mutations+in+the+PANK2+gene. assertion.
- assertion asSentence Calmodulin+and+S100A1+protein+interact+with+N+terminus+of+TRPM3+channel. assertion.
- assertion asSentence PGAP1+encoded+an+ER-associated%2C+922-amino+acid+membrane+protein+bearing+a+lipase+consensus+motif. assertion.
- assertion asSentence Supramodular+nature+of+GRIP1+revealed+by+the+structure+of+its+PDZ12+tandem+in+complex+with+the+carboxhyl+tail+of+Fras1. assertion.
- assertion asSentence MCPIP1+ribonuclease+antagonizes+dicer+and+terminates+microRNA+biogenesis+through+precursor+microRNA+degradation. assertion.
- assertion asSentence Structural+basis+for+the+mutually+exclusive+anchoring+of+P+body+components+EDC3+and+Tral+to+the+DEAD+box+protein+DDX6%2FMe31B. assertion.
- assertion asSentence NATH+complexes+with+hARD1+in+a+ribosomal+associated+protein-N-acetyltransferase+complex. assertion.
- assertion asSentence SSB1%2F2+is+part+of+an+ssDNA-binding+heterotrimeric+complex%2C+SOSS+which+is+involved+in+the+maintenance+of+genome+stability. assertion.
- assertion asSentence CEP290+c.2991_1655A%3EG+mutation+frequency+in+Spanish+non-syndromic+Leber+congenital+amaurosis+families+is+lower+than+that+of+other+countries. assertion.
- assertion asSentence CEP290+binds+to+PCM-1+and+localizes+to+centriolar+satellites+in+a+PCM-1-+and+microtubule-dependent+manner. assertion.
- assertion asSentence Mus81+binds+to+a+homolog+of+fission+yeast+Eme1+in+vitro+and+in+vivo+and+Mus81-Eme1+resolves+Holliday+junctions+in+vivo. assertion.
- assertion asSentence Mus81-Eme1+can+ensure+coordinate%2C+bilateral+cleavage+of+Holliday+junction-like+structures. assertion.
- assertion asSentence MUS81+is+involved+in+the+maintenance+of+ALT+%28alternative+lengthening+of+telomeres%29+cell+survival+at+least+in+part+by+homologous+recombination+of+telomeres. assertion.
- assertion asSentence FBXO11+has+a+lower+expression+in+skin+lesion+tissues+than+in+normal+tissues+from+vitiligo+patients. assertion.
- assertion asSentence Actin+dynamics+regulated+by+Fhod3+are+critical+for+sarcomere+organization+in+striated+muscle+cells. assertion.
- assertion asSentence The+mouse+ortholog+of+OPA3+purifies+with+mitochondrial+inner+membranes. assertion.
- assertion asSentence SPG11%2C+the+most+frequent+gene+associated+with+hereditary+spastic+paraplegia+with+thin+corpus+callosum+%28HSP-TCC%29+encodes+spatacsin%2C+demonstrating+the+extensive+genetic+heterogeneity+of+this+condition. assertion.
- assertion asSentence Endothelium-specific+overexpression+of+human+IC53+downregulates+endothelial+nitric+oxide+synthase+activity+and+elevates+systolic+blood+pressure+in+mice. assertion.
- assertion asSentence PDGF+D+is+activated+and+processed+by+urokinase+plasminogen+activator+and+they+colocalize+in+human+prostate+carcinoma. assertion.
- assertion asSentence Human+umbilical+cord+blood+tropism+toward+glioma+cells+are+partially+dependent+on+the+PDGF%2FPGGFR+system. assertion.
- assertion asSentence Investigation+of+the+sequence+and+structural+requirements+for+hPus1p+activity+on+human+tRNASer. assertion.
- assertion asSentence Mantle+cell+lymphoma+highly+and+consistently+expressed+Wnt3+and+Wnt10. assertion.
- assertion asSentence ULBP2+binds+to+the+NKG2D+receptor+and+activates+multiple+signaling+pathways+in+primary+natural+killer+cells. assertion.
- assertion asSentence ULBPs+and+MICA+are+expressed+in+lipid+rafts+at+the+cell+surface+of+NK+and+T+cells. assertion.
- assertion asSentence ULBP1+binds+to+the+NKG2D+receptor+and+activates+multiple+signaling+pathways+in+primary+natural+killer+cells. assertion.
- assertion asSentence As+NKG2D+ligand%2C+ULBP1+are+expressed+on+immature+dendritic+cells+and+plays+an+important+role+in+the+cytotoxic+effect+of+NK+cells+against+iDC. assertion.
- assertion asSentence Has+a+role+in+exocytosis+of+large+dense+core+vesicles. assertion.
- assertion asSentence Sequence+variations+in+ADAM33+are+associated+with+susceptibility+to+aspirin-intolerant+asthama+in+the+Japanese+population. assertion.
- assertion asSentence There+is+an+association+between+ADAM33+polymorphisms+and+chronic+obstructive+pulmonary+disease+in+Tibetan+population+of+China. assertion.
- assertion asSentence Mutation+of+KCNIP4+is+associated+with+renal+cell+carcinoma. assertion.
- assertion asSentence CALP+and+calsenilin+are+involved+in+the+trafficking+of+Golgi+glycosyltransferases. assertion.
- assertion asSentence No+association+of+a+single+nucleotide+polymorphism+in+the+adiponutrin+gene+and+type+2+diabetes+in+a+Chinese+population. assertion.
- assertion asSentence Genetic+variation+at+PNPLA3+confers+a+markedly+increased+risk+of+increasingly+severe+histological+features+of+nonalcoholic+fatty+liver+disease%2C+without+a+strong+effect+on+metabolic+syndrome+component+traits. assertion.
- assertion asSentence Genotype+PNPLA3+rs738409%28GG%29+is+associated+with+alcoholic+liver+cirrhosis+and+elevated+aminotransferase+levels+in+alcoholic+Caucasians. assertion.
- assertion asSentence CoA+synthase+is+involved+in+signaling+events+in+the+cell+and+forms+a+functional+complex+with+p85alphaPI3K+in+vivo. assertion.
- assertion asSentence Overexpression+of+B7H3+is+associated+with+tumor+cell+migration+and+invasion. assertion.
- assertion asSentence THTR2+is+involved+in+thiamine+transport+by+reginal+pigment+epithelium. assertion.
- assertion asSentence G6b-B+inhibits+constitutive+and+agonist-induced+signaling+by+glycoprotein+VI+and+CLEC-2. assertion.
- assertion asSentence Promoter+methylation-mediated+loss+of+ITIH5+expression+is+associated+with+unfavourable+outcome+in+breast+cancer+patients. assertion.
- assertion asSentence ITIH5+gene+expression+is+regulated+both+by+obesity+and+by+the+region+between+visceral+and+subcutaneous+adipose+tissue. assertion.