Matches in Nanopublications for { ?s <http://purl.org/nanopub/x/asSentence> ?o ?g. }
- assertion asSentence The+21+kDa+protein+overexpressed+in+Hodgkin+Lymphoma+and+aggressive+non-Hodgkin+Lymphomas+is+identical+to+CYB5B. assertion.
- assertion asSentence Expression+of+collagen+XVIII+in+tumor+tissue+is+strongly+associated+with+a+poorer+outcome+in+non-small-cell+lung+cancer+and+correlates+with+elevated+levels+of+circulating+serum+endostatin. assertion.
- assertion asSentence Naked+endostatin+plasmid+intratumoral+injection+can+get+a+similar+gene+transfection+efficiency+to+liposome-DNA+complex+when+used+in+situ+in+inhibiting+cell+growth. assertion.
- assertion asSentence Recombinant+human+endostatin+inhibits+choroidal+neovascularization+lesion+size+and+vascular+leakage+in+mutant+mice+lacking+collagen+XVIII+as+a+structural+membrane+component. assertion.
- assertion asSentence Zn%28II%29-binding+contributes+to+the+structural+integrity+of+endostatin. assertion.
- assertion asSentence Endostatin+and+angiostatin+are+increased+in+diabetic+patients+with+coronary+artery+disease+and+associated+with+impaired+coronary+collateral+formation. assertion.
- assertion asSentence Airway+concentrations+of+angiopoietin-1+and+endostatin+in+ventilated+extremely+premature+infants+are+decreased+after+funisitis+and+unbalanced+with+bronchopulmonary+dysplasia%2Fdeath. assertion.
- assertion asSentence Elevated+preoperative+serum+levels+of+endostatin+in+patients+with+clear+cell+renal+cell+carcinoma+are+associated+with+higher+stage+and+grade. assertion.
- assertion asSentence Arginine+clusters+in+the+heparin+binding+motif+of+endostatin+significantly+contribute+to+its+interaction+with+receptor+nucleolin+and+mediate+the+antiangiogenic+and+antitumor+activities+of+endostatin. assertion.
- assertion asSentence C-mip+inhibits+the+degradation+of+I-kappaBalpha+and+impedes+the+dissociation+of+the+NF-kappaB%2FI-kappaBalpha+complexes. assertion.
- assertion asSentence DUSPs+10+and+16+are+positive+regulators+of+activation%2C+apparently+acting+by+modulating+cross-talk+between+the+p38+and+ERK+pathways. assertion.
- assertion asSentence The+mechanism+of+interaction+of+the+sweet+protein+monellin+with+the+T1R2-T1R3+receptor. assertion.
- assertion asSentence Genetic+ablation+of+the+sweet+TR+protein+T1R2+obliterates+fructose-induced+insulin+release+and+its+potentiating+effects+on+glucose-stimulated+insulin+secretion+in+vitro+and+in+vivo. assertion.
- assertion asSentence Set7%2F9-KMT7+associates+with+the+HIV+promoter+in+vivo+and+monomethylates+lysine+51%2C+a+highly+conserved+residue+located+in+the+RNA-binding+domain+of+Tat. assertion.
- assertion asSentence Mutation+of+the+beta1-tubulin+gene+associated+with+congenital+macrothrombocytopenia+affecting+microtubule+assembly. assertion.
- assertion asSentence hZbeta%28DAI%29+binds+to+Z-DNA+via+an+active-di+B-Z+transition+mechanism. assertion.
- assertion asSentence Solution+structure+of+the+Zbeta+domain+of+human+DNA-dependent+activator+of+IFN-regulatory+factors+and+its+binding+modes+to+B-+and+Z-DNAs. assertion.
- assertion asSentence CL-P1+predominantly+mediated+phagocytosis+for+fungi+in+vascular+endothelia. assertion.
- assertion asSentence The+Le%28x%29+residues+of+both%2C+CEACAM1+and+CEA%2C+interact+with+the+human+Le%28x%29-binding+glycan+receptors+DC-SIGN+and+SRCL. assertion.
- assertion asSentence Single-nucleotide+polymorphisms+in+CLPTM1L+is+associated+with+lung+cancer. assertion.
- assertion asSentence Syncoilin+modulates+peripherin+filament+network+formation. assertion.
- assertion asSentence IMP1+is+a+bi-aspartic+polytopic+protease+capable+of+cleaving+transmembrane+proteins+such+as+presenilin+2. assertion.
- assertion asSentence SPP1+by+regulating+intracellular+S1P+homeostasis%2C+can+control+the+UPR+and+ER+stress-induced+autophagy. assertion.
- assertion asSentence SNAT1+is+a+key+contributor+to+system+A+activity+at+term. assertion.
- assertion asSentence NDEL1+significantly+influences+risk+for+schizophrenia+via+an+interaction+with+DISC1. assertion.
- assertion asSentence LBH+is+aberrantly+overexpressed+in+mammary+tumors+of+mouse+mammary+tumor+virus+%28MMTV%29-Wnt1-transgenic+mice+and+in+aggressive+basal+subtype+human+breast+cancers+that+display+Wnt%2Fbeta-catenin+hyperactivation. assertion.
- assertion asSentence Overexpression+of+SNX17+in+mammalian+cells+promotes+the+endocytosis+of+P-selectin+from+the+plasma+membrane+and+inhibits+its+movement+into+lysosomes. assertion.
- assertion asSentence PCNA+is+involved+in+mediating+Cdt1+degradation+by+the+Cul4-Ddb1+ligase+in+response+to+DNA+damage. assertion.
- assertion asSentence L2DTL+and+PCNA+interact+with+CUL4%2FDDB1+complexes+and+are+involved+in+CDT1+degradation+after+DNA+damage. assertion.
- assertion asSentence FOXO3+is+a+binding+partner+of+Cdt1. assertion.
- assertion asSentence Isoform-selective+actin+assembly+by+DIAPH3+exerts+specific+and+differentially+regulated+functions+during+cell+adhesion+and+motility. assertion.
- assertion asSentence Endogenously+expressed+Vmp1+is+essentially+a+cell+membrane+protein+that+is+involved+in+cell-cell+adhesion%2C+invasion+and+metastasis. assertion.
- assertion asSentence Required+for+functional+heme+biosynthesis+in+erythroid+cells. assertion.
- assertion asSentence Involvement+of+DOCK8+in+processes+that+affect+the+organisation+of+filamentous+actin. assertion.
- assertion asSentence RNF170+plays+an+essential+role+in+IP%283%29+receptor+processing+via+the+ubiquitin-proteasome+pathway. assertion.
- assertion asSentence No+significant+differences+are+found+in+the+TLR3+and+TLR10+genotypes+or+allele+distribution+between+rheumatoid+arthritis+patients+and+control+individuals. assertion.
- assertion asSentence Pam%283%29CSK%284%29+is+the+ligand+for+the+hTLR10%2F2+complex+and+PamCysPamSK4+activates+hTLR10%2F1+hetero+and+hTLR10+homodimer. assertion.
- assertion asSentence Absence+of+the+common+haplotype+in+the+TLR10-TLR1-TLR6+gene+cluster+increases+the+risk+of+developing+chronic+disease+in+patients+already+affected+by+sarcoidosis. assertion.
- assertion asSentence Mutations+in+ADAMTS10+gene+is+not+responsible+for+microspherophakia. assertion.
- assertion asSentence Mouse+neto1+plays+a+critical+role+in+spatial+learning+and+memory+through+the+regulation+of+NMDAR+subunit+abundance+at+synapses. assertion.
- assertion asSentence KITENIN+plays+an+important+role+in+human+gastric+cancer+progression+by+AP-1+activation. assertion.
- assertion asSentence TRIM56+is+an+interferon-inducible+E3+ubiquitin+ligase+that+modulates+STING+to+confer+double-stranded+DNA-mediated+innate+immune+responses. assertion.
- assertion asSentence SHARPIN+inhibits+the+critical+switching+of+beta1-integrins+from+inactive+to+active+conformations. assertion.
- assertion asSentence SLIRP+plays+an+essential+role+in+maintaining+mitochondrial-localized+mRNA+transcripts+that+encode+OxPhos+protein+subunits. assertion.
- assertion asSentence The+kinesin-8+Kif18A+dampens+microtubule+plus-end+dynamics. assertion.
- assertion asSentence High+Kif18A+is+associated+with+breast+carcinogenesis. assertion.
- assertion asSentence Fc+receptor-like+1-5+molecules+are+similarly+expressed+in+progressive+and+indolent+clinical+subtypes+of+B-cell+chronic+lymphocytic+leukemia. assertion.
- assertion asSentence Monocytoid+B+cells+differ+in+their+antigen+profile+%28presence+of+IRTA1%29+from+splenic+and+nodal+marginal+zone+B+cells. assertion.
- assertion asSentence Cell+surface+expression+of+this+immunoregulatory+molecule+is+restricted+to+a+subpopulation+of+memory+B+cells. assertion.
- assertion asSentence Fc+receptor-like+1-5+molecules+are+similarly+expressed+in+progressive+and+indolent+clinical+subtypes+of+B-cell+chronic+lymphocytic+leukemia. assertion.
- assertion asSentence PV1+is+a+key+structural+component%2C+necessary+for+the+biogenesis+of+the+stomatal+and+fenestral+diaphragms. assertion.
- assertion asSentence The+crystal+structure+of+Rab7-GTP+in+complex+with+the+Rab7+binding+domain+of+RILP+reveals+that+Rab7+interacts+with+RILP+specifically+via+two+distinct+areas. assertion.
- assertion asSentence NORE1A+activates+p21%28CIP1%29+via+promoting+p53+nuclear+localization. assertion.
- assertion asSentence BCL2L12+mRNA+expression+is+significantly+higher+in+CLL+patients+than+in+healthy+blood+donors. assertion.
- assertion asSentence In+breast+cancer+cells+SESN2+is+associated+with+AMPK. assertion.
- assertion asSentence Human+deafness+and+vestibular+dysfunction+co-segregated+with+either+of+two+frameshift+mutations+in+ESPN. assertion.
- assertion asSentence Reults+demonstrate+the+function+of+atrophin-1-interacting+protein+4+as+an+ubiquitin+E3+ligase+for+human+enhancer+of+filamentation+1. assertion.
- assertion asSentence Ubiquitination+of+cFLIP%28L%29+inhibits+the+interaction+between+cFLIP%28L%29+and+Itch+in+T.+cruzi-infected+cells. assertion.
- assertion asSentence Expressed+in+the+sweet%2Fumami+gustatory+pathways+in+taste+receptor+cells+and+trigeminal+neural+pathways+in+transgenic+mice. assertion.
- assertion asSentence The+heteromeric+G-protein-coupled+receptor+T1R2%3AT1R3+responds+to+a+vast+array+of+chemically+diverse+natural+and+artificial+sweeteners. assertion.
- assertion asSentence The+sweet+taste+receptors+%28alpha-gustducin+and+T1R3%29+are+involved+in+glucose-stimulated+secretion+of+GLP-1+and+PYY. assertion.
- assertion asSentence Targeted+insertion+in+human+embryonic+stem+cells+of+sequences+encoding+green+fluorescent+protein+%28GFP%29+into+the+locus+of+MIXL1%2C+a+gene+transiently+expressed+in+the+primitive+streak+during+embryogenesis. assertion.
- assertion asSentence Secreted+from+NK+cells+in+decidua%2C+elevated+at+late+gestational+period. assertion.
- assertion asSentence SNX25+negatively+regulates+TGF-beta+signaling+by+enhancing+the+receptor+degradation+through+lysosome+pathway. assertion.
- assertion asSentence Haspin+is+required+to+maintain+centromeric+cohesion+during+mitosis. assertion.
- assertion asSentence Haspin-depleted+cells+reveal+that+spindle-pole+integrity+in+mitosis+requires+chromosome+cohesion. assertion.
- assertion asSentence Tyrosine+phosphorylation+acts+as+a+molecular+switch+to+full-scale+activation+of+the+eIF2alpha+RNA-dependent+protein+kinase. assertion.
- assertion asSentence Comprehensive+survey+of+naturally+occurring+polymorphisms+in+rhesus+macaques+and+in+humans. assertion.
- assertion asSentence The+corneal+dystrophy+and+perceptive+deafness+%28Harboyan+syndrome%29+gene+%28CDPD1%29+maps+to+chromosome+20p13. assertion.
- assertion asSentence CHED2+%28congenital+hereditary+endothelial+dystrophy%29+is+associated+with+mutations+in+SLC4A11%2C+a+member+of+the+SLC4+family+of+base+transporters. assertion.
- assertion asSentence p90+is+a+critical+cofactor+for+p53-mediated+apoptosis+through+promoting+Tip60-mediated+p53+acetylation. assertion.
- assertion asSentence The+X-ray+crystal+structure+at+a+resolution+of+1.85+A+of+the+BRCA1+tandem+BRCT+domains+in+complex+with+a+phosphorylated+peptide+representing+the+minimal+interacting+region+of+the+DEAH-box+helicase+BACH1. assertion.
- assertion asSentence Recurrent+truncating+germline+mutation+in+the+BRIP1+gene+is+associated+with+prostate+cancer. assertion.
- assertion asSentence Epac+inhibits+migration+and+proliferation+of+human+prostate+carcinoma+cells. assertion.
- assertion asSentence In+human+cells+BRCA1+binding+to+FANCJ+is+critical+to+regulate+DNA+repair+choice+and+promote+genomic+stability. assertion.
- assertion asSentence CORTBP2+%28CTTNBP2%29+has+a+transcription-dependent+spatial+arrangement. assertion.
- assertion asSentence Overexpression+of+REGIV+mRNA+is+assessed+with+peritoneal+recurrence+in+gastric+adenocarcinoma. assertion.
- assertion asSentence The+possibility+of+using+EMILIN2+fragments+as+potent+antineoplastic+tools+for+cancer+treatment. assertion.
- assertion asSentence In+mouse%2C+dysbindin+binds+to+alpha-+and+beta-dystrobrevin+in+muscle+and+brain. assertion.
- assertion asSentence NF-kappaB+and+Sp1+response+elements+are+essential+for+the+basal+transcriptional+activity+of+the+Neph3+promoter. assertion.
- assertion asSentence Bardet-Biedl+syndrome-associated+small+GTPase+ARL6+%28BBS3%29+functions+at+or+near+the+ciliary+gate+and+modulates+Wnt+signaling. assertion.
- assertion asSentence PRAM-1+is+required+for+optimal+integrin-dependent+neutrophil+function. assertion.
- assertion asSentence ATRIP+is+required+for+ATR+accumulation+at+intranuclear+foci+induced+by+DNA+damage. assertion.
- assertion asSentence The+recurrent+Abraxas+c.1082G%3EA+mutation+connects+to+breast+cancer+predisposition. assertion.
- assertion asSentence No+significant+association+of+BDNF+or+DARPP-32+polymorphisms+with+schizophrenia+in+Malays. assertion.
- assertion asSentence Examination+of+the+effect+of+several+Aicardi-Goutieres+Syndrome-related+mutations+in+the+C+subunit+of+RNase+H2. assertion.
- assertion asSentence ARID5B+SNP+rs10821936+is+associated+with+risk+of+childhood+acute+lymphoblastic+leukemia+in+blacks+and+contributes+to+racial+differences+in+leukemia+incidence. assertion.
- assertion asSentence Single+nucleotide+polymorphism+in+ARID5B+gene+is+associated+with+childhood+acute+lymphoblastic+leukemia. assertion.
- assertion asSentence GTF2IRD2+genes+in+mice+and+humans+allows+refinement+of+the+centromeric+breakpoint+position+of+the+primate-specific+inversion+within+the+Williams-Beuren+syndrome+critical+region. assertion.
- assertion asSentence NLRC5+is+a+critical+component+of+inflammasome-dependent+interleukin+%28IL%29-1beta+secretion+in+response+to+a+repertoire+of+stimuli+that+also+activate+NLRP3. assertion.
- assertion asSentence SNPs+in+the+lysyl+oxidase-like+protein+4+and+complement+component+3+genes+are+associated+with+increased+risk+for+endometriosis+and+endometriosis-associated+infertility+in+a+Puerto+Rican+population. assertion.
- assertion asSentence Maf1%2C+a+repressor+that+binds+and+inhibits+pol+III%2C+is+phosphorylated+in+a+mTOR-dependent+manner+both+in+vitro+and+in+vivo+at+serine+75%2C+a+site+that+contributes+to+its+function+as+a+transcriptional+inhibitor. assertion.
- assertion asSentence SGIP1+and+the+signaling+adaptor+Reps1+interact+with+ITSN1+in+vivo. assertion.
- assertion asSentence SKAR-mediated+recruitment+of+activated+S6K1+to+newly+processed+mRNPs+serves+as+a+conduit+between+mTOR+checkpoint+signaling+and+the+pioneer+round+of+translation+when+cells+exist+in+conditions+supportive+of+protein+synthesis. assertion.
- assertion asSentence RNF135+mutations+are+not+present+in+patients+with+Sotos+syndrome-like+features. assertion.
- assertion asSentence Success+of+PHF6+screening+in+males+suspected+of+having+Borjeson-Forssman-Lehmann+syndrome+is+markedly+increased+if+there+is+a+positive+family+history+and%2For+skewed+X-inactivation+is+found+in+the+mother. assertion.
- assertion asSentence PHF6+as+a+tumor+suppressor+gene+mutated+in+acute+myeloid+leukemias+%28AML%29+and+extend+the+role+of+this+X-linked+tumor+suppressor+gene+in+the+pathogenesis+of+hematologic+tumors. assertion.
- assertion asSentence The+Hv1+channel+voltage+sensor+domain+by+itself+supports+H%28%2B%29+flux. assertion.
- assertion asSentence PRAS40+regulates+mTORC1+kinase+activity+by+functioning+as+a+direct+inhibitor+of+substrate+binding. assertion.
- assertion asSentence EF-G2mt+is+an+exclusive+recycling+factor+in+mammalian+mitochondrial+protein+synthesis. assertion.