Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB00203_nanopub.RAzn3f2nmbTNYPO4xPDdm48s2ezcEeWVoc8ixUFvsjpGA#assertion>. }
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- drugbank:DB00203 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00203 label "Sildenafil [drugbank:DB00203]" assertion.
- drugbank:DB00203 seeAlso viagra.htm assertion.
- drugbank:DB00203 seeAlso rx-mono.aspx?contentFileName=via1479.html&contentName=Viagra&contentId=818 assertion.
- drugbank:DB00203 seeAlso sildenafil.html assertion.
- drugbank:DB00203 seeAlso DB00203 assertion.
- drugbank:DB00203 description "Sildenfail is a vasoactive agent used to treat erectile dysfunction and reduce symptoms in patients with pulmonary arterial hypertension (PAH). Sildenafil elevates levels of the second messenger, cGMP, by inhibiting its breakdown via phosphodiesterase type 5 (PDE5). PDE5 is found in particularly high concentrations in the corpus cavernosum, erectile tissue of the penis. It is also found in the retina and vascular endothelium. Increased cGMP results in vasodilation which facilitates generation and maintenance of an erection. The vasodilatory effects of sildenafil also help reduce symptoms of PAH." assertion.
- drugbank:DB00203 identifier "drugbank:DB00203" assertion.
- drugbank:DB00203 title "Sildenafil" assertion.
- drugbank:DB00203 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46508371 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-pubchemcompound pubchem.compound:5212 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-chemspider chemspider:5023 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-cas cas:139755-83-2 assertion.
- drugbank:DB00203 drugbank_vocabulary:drugbank-id "APRD00556" assertion.
- drugbank:DB00203 drugbank_vocabulary:drugbank-id "DB00203" assertion.
- drugbank:DB00203 bio2rdf_vocabulary:x-identifiers.org DB00203 assertion.
- drugbank:DB00203 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00203" assertion.
- drugbank:DB00203 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00203 bio2rdf_vocabulary:identifier "DB00203" assertion.
- drugbank:DB00203 drugbank_vocabulary:x-wikipedia wikipedia:Sildenafil assertion.
- drugbank:DB00203 drugbank_vocabulary:x-pharmgkb pharmgkb:PA451346 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-kegg kegg:D02229 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-kegg kegg:C07259 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-dpd dpd:2239766 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-chebi chebi:9139 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-atc atc:G04BE03 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-ahfs ahfs:24:12.12 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-bindingdb bindingdb:14390 assertion.
- drugbank:DB00203 drugbank_vocabulary:x-ndc ndc:0069-4190-68 assertion.