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- drugbank:DB00419 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00419 label "Miglustat [drugbank:DB00419]" assertion.
- drugbank:DB00419 seeAlso zavesca.htm assertion.
- drugbank:DB00419 seeAlso miglustat.html assertion.
- drugbank:DB00419 seeAlso DB00419 assertion.
- drugbank:DB00419 description "Miglustat is a drug used to treat Gaucher disease. It inhibits the enzyme glucosylceramide synthase, an essential enzyme for the synthesis of most glycosphingolipids. It is only used for patients who cannot be treated with enzyme replacement therapy with imiglucerase. Miglustat is marketed under the trade name Zavesca. Miglustat is now the first and only approved therapy for patients with Niemann-Pick disease type C (NP-C). It has recently been approved for treatment of progressive neurological symptoms in adult and pediatric patients in the European Union, Brazil, and South Korea. Miglustat was first developed as an anti-HIV agent in the 1990s. However, clinical experience with miglustat showed that therapeutic levels of the drug could not be achieved in patients without a high incidence of adverse effect." assertion.
- drugbank:DB00419 identifier "drugbank:DB00419" assertion.
- drugbank:DB00419 title "Miglustat" assertion.
- drugbank:DB00419 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46506350 assertion.
- drugbank:DB00419 drugbank_vocabulary:x-pubchemcompound pubchem.compound:51634 assertion.
- drugbank:DB00419 drugbank_vocabulary:x-chemspider chemspider:46764 assertion.
- drugbank:DB00419 drugbank_vocabulary:x-cas cas:72599-27-0 assertion.
- drugbank:DB00419 drugbank_vocabulary:drugbank-id "APRD01118" assertion.
- drugbank:DB00419 drugbank_vocabulary:drugbank-id "DB00419" assertion.
- drugbank:DB00419 bio2rdf_vocabulary:x-identifiers.org DB00419 assertion.
- drugbank:DB00419 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00419" assertion.
- drugbank:DB00419 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00419 bio2rdf_vocabulary:identifier "DB00419" assertion.
- drugbank:DB00419 drugbank_vocabulary:x-wikipedia wikipedia:Miglustat assertion.
- drugbank:DB00419 drugbank_vocabulary:x-pharmgkb pharmgkb:PA10140 assertion.
- drugbank:DB00419 drugbank_vocabulary:x-dpd dpd:2250519 assertion.
- drugbank:DB00419 drugbank_vocabulary:x-chebi chebi:50381 assertion.
- drugbank:DB00419 drugbank_vocabulary:x-atc atc:A16AX06 assertion.
- drugbank:DB00419 drugbank_vocabulary:x-ahfs ahfs:92:00.00 assertion.
- drugbank:DB00419 drugbank_vocabulary:x-bindingdb bindingdb:18355 assertion.