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- drugbank:DB00605 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00605 label "Sulindac [drugbank:DB00605]" assertion.
- drugbank:DB00605 seeAlso sulindac.htm assertion.
- drugbank:DB00605 seeAlso cli1087.shtml assertion.
- drugbank:DB00605 seeAlso sulindac.html assertion.
- drugbank:DB00605 seeAlso DB00605 assertion.
- drugbank:DB00605 description "Sulindac is a nonsteroidal anti-inflammatory agent (NSAIA) of the arylalkanoic acid class that is marketed in the U.S. by Merck as Clinoril. Like other NSAIAs, it may be used in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in vivo to an active sulfide compound by liver enzymes. The sulfide metabolite then undergoes enterohepatic circulation; it is excreted in the bile and then reabsorbed from the intestine. This is thought to help maintain constant blood levels with reduced gastrointestinal side effects. Some studies have shown sulindac to be relatively less irritating to the stomach than other NSAIA's except for drugs of the cyclooxygenase-2 (COX-2) inhibitor class. The exact mechanism of its NSAIA properties is unknown, but it is thought to act on enzymes COX-1 and COX-2, inhibiting prostaglandin synthesis." assertion.
- drugbank:DB00605 identifier "drugbank:DB00605" assertion.
- drugbank:DB00605 title "Sulindac" assertion.
- drugbank:DB00605 drugbank_vocabulary:x-cas cas:38194-50-2 assertion.
- drugbank:DB00605 drugbank_vocabulary:drugbank-id "APRD01243" assertion.
- drugbank:DB00605 drugbank_vocabulary:drugbank-id "DB00605" assertion.
- drugbank:DB00605 bio2rdf_vocabulary:x-identifiers.org DB00605 assertion.
- drugbank:DB00605 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00605" assertion.
- drugbank:DB00605 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00605 bio2rdf_vocabulary:identifier "DB00605" assertion.
- drugbank:DB00605 drugbank_vocabulary:x-wikipedia wikipedia:Sulindac assertion.
- drugbank:DB00605 drugbank_vocabulary:x-pharmgkb pharmgkb:PA451565 assertion.
- drugbank:DB00605 drugbank_vocabulary:x-kegg kegg:D00120 assertion.
- drugbank:DB00605 drugbank_vocabulary:x-kegg kegg:C01531 assertion.
- drugbank:DB00605 drugbank_vocabulary:x-dpd dpd:808636 assertion.
- drugbank:DB00605 drugbank_vocabulary:x-chebi chebi:9352 assertion.
- drugbank:DB00605 drugbank_vocabulary:x-atc atc:M01AB02 assertion.
- drugbank:DB00605 drugbank_vocabulary:x-ahfs ahfs:28:08.04.92 assertion.
- drugbank:DB00605 drugbank_vocabulary:x-ndc ndc:0006-0941-68 assertion.