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- drugbank:DB00612 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00612 label "Bisoprolol [drugbank:DB00612]" assertion.
- drugbank:DB00612 seeAlso bisoprolol.htm assertion.
- drugbank:DB00612 seeAlso zeb1667.shtml assertion.
- drugbank:DB00612 seeAlso bisoprolol.html assertion.
- drugbank:DB00612 seeAlso DB00612 assertion.
- drugbank:DB00612 description "Bisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. Bisoprolol is structurally similar to metoprolol, acebutolol and atenolol in that it has two substituents in the <i>para</i> position of the benzene ring. The β1-selectivity of these agents is thought to be due in part to the large substituents in the <i>para</i> position. At lower doses (less than 20 mg daily), bisoprolol selectively blocks cardiac β1-adrenergic receptors with little activity against β2-adrenergic receptors of the lungs and vascular smooth muscle. Receptor selectivity decreases with daily doses of 20 mg or greater. Unlike propranolol and pindolol, bisoprolol does not exhibit membrane-stabilizing or sympathomimetic activity. Bisoprolol possesses a single chiral centre and is administered as a racemic mixture. Only <i>l</i>-bisoprolol exhibits significant β-blocking activity." assertion.
- drugbank:DB00612 identifier "drugbank:DB00612" assertion.
- drugbank:DB00612 title "Bisoprolol" assertion.
- drugbank:DB00612 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46508844 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-pubchemcompound pubchem.compound:2405 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-chemspider chemspider:2312 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-cas cas:66722-44-9 assertion.
- drugbank:DB00612 drugbank_vocabulary:drugbank-id "APRD00257" assertion.
- drugbank:DB00612 drugbank_vocabulary:drugbank-id "DB00612" assertion.
- drugbank:DB00612 bio2rdf_vocabulary:x-identifiers.org DB00612 assertion.
- drugbank:DB00612 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00612" assertion.
- drugbank:DB00612 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00612 bio2rdf_vocabulary:identifier "DB00612" assertion.
- drugbank:DB00612 drugbank_vocabulary:x-wikipedia wikipedia:Bisoprolol assertion.
- drugbank:DB00612 drugbank_vocabulary:x-pharmgkb pharmgkb:PA448641 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-kegg kegg:D02342 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-kegg kegg:C06852 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-dpd dpd:2247439 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-chebi chebi:3127 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-atc atc:C07AB07 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-ahfs ahfs:24:24.00 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-bindingdb bindingdb:25751 assertion.
- drugbank:DB00612 drugbank_vocabulary:x-ndc ndc:0378-0523-93 assertion.