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- drugbank:DB00641 type drugbank_vocabulary:Drug assertion.
- drugbank:DB00641 label "Simvastatin [drugbank:DB00641]" assertion.
- drugbank:DB00641 seeAlso simva.htm assertion.
- drugbank:DB00641 seeAlso zoc1500.shtml assertion.
- drugbank:DB00641 seeAlso simvastatin.html assertion.
- drugbank:DB00641 seeAlso DB00641 assertion.
- drugbank:DB00641 description "Simvastatin is a lipid-lowering agent that is derived synthetically from the fermentation of Aspergillus terreus. It is a potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (hydroxymethylglutaryl COA reductases), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL receptors, it increases breakdown of LDL cholesterol. [PubChem]" assertion.
- drugbank:DB00641 identifier "drugbank:DB00641" assertion.
- drugbank:DB00641 title "Simvastatin" assertion.
- drugbank:DB00641 drugbank_vocabulary:x-pdb pdb:SIM assertion.
- drugbank:DB00641 drugbank_vocabulary:x-cas cas:79902-63-9 assertion.
- drugbank:DB00641 drugbank_vocabulary:drugbank-id "APRD00104" assertion.
- drugbank:DB00641 drugbank_vocabulary:drugbank-id "DB00641" assertion.
- drugbank:DB00641 bio2rdf_vocabulary:x-identifiers.org DB00641 assertion.
- drugbank:DB00641 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB00641" assertion.
- drugbank:DB00641 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB00641 bio2rdf_vocabulary:identifier "DB00641" assertion.
- drugbank:DB00641 drugbank_vocabulary:x-wikipedia wikipedia:Simvastatin assertion.
- drugbank:DB00641 drugbank_vocabulary:x-pharmgkb pharmgkb:PA451363 assertion.
- drugbank:DB00641 drugbank_vocabulary:x-kegg kegg:D00434 assertion.
- drugbank:DB00641 drugbank_vocabulary:x-dpd dpd:2253747 assertion.
- drugbank:DB00641 drugbank_vocabulary:x-chebi chebi:9150 assertion.
- drugbank:DB00641 drugbank_vocabulary:x-atc atc:C10AA01 assertion.
- drugbank:DB00641 drugbank_vocabulary:x-ahfs ahfs:24:06.08 assertion.
- drugbank:DB00641 drugbank_vocabulary:x-ndc ndc:16714-681-01 assertion.