Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB01109_nanopub.RA5pIOv0MBuh1Q3Omy1uiEzQEfdGkUmKPz2EgTS6M2KdA#assertion>. }
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- drugbank:DB01109 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01109 label "Heparin [drugbank:DB01109]" assertion.
- drugbank:DB01109 seeAlso heparin.htm assertion.
- drugbank:DB01109 seeAlso heparin.html assertion.
- drugbank:DB01109 seeAlso DB01109 assertion.
- drugbank:DB01109 description "Unfractionated heparin (UH) is a heterogenous preparation of anionic, sulfated glycosaminoglycan polymers with weights ranging from 3000 to 30,000 Da. It is a naturally occurring anticoagulant released from mast cells. It binds reversibly to antithrombin III (ATIII) and greatly accelerates the rate at which ATIII inactivates coagulation enzymes thrombin (factor IIa) and factor Xa. UH is different from low molecular weight heparin (LMWH) in the following ways: the average molecular weight of LMWH is about 4.5 kDa whereas it is 15 kDa for UH; UH requires continuous infusions; activated partial prothrombin time (aPTT) monitoring is required when using UH; and UH has a higher risk of bleeding and higher risk of osteoporosis in long term use. Unfractionated heparin is more specific than LMWH for thrombin. Furthermore, the effects of UH can typically be reversed by using protamine sulfate." assertion.
- drugbank:DB01109 identifier "drugbank:DB01109" assertion.
- drugbank:DB01109 title "Heparin" assertion.
- drugbank:DB01109 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46507594 assertion.
- drugbank:DB01109 drugbank_vocabulary:x-chemspider chemspider:751 assertion.
- drugbank:DB01109 drugbank_vocabulary:x-cas cas:9005-49-6 assertion.
- drugbank:DB01109 drugbank_vocabulary:drugbank-id "APRD00056" assertion.
- drugbank:DB01109 drugbank_vocabulary:drugbank-id "DB01109" assertion.
- drugbank:DB01109 bio2rdf_vocabulary:x-identifiers.org DB01109 assertion.
- drugbank:DB01109 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01109" assertion.
- drugbank:DB01109 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01109 bio2rdf_vocabulary:identifier "DB01109" assertion.
- drugbank:DB01109 drugbank_vocabulary:x-wikipedia wikipedia:Heparin assertion.
- drugbank:DB01109 drugbank_vocabulary:x-pharmgkb pharmgkb:PA449855 assertion.
- drugbank:DB01109 drugbank_vocabulary:x-kegg kegg:C00374 assertion.
- drugbank:DB01109 drugbank_vocabulary:x-dpd dpd:453781 assertion.
- drugbank:DB01109 drugbank_vocabulary:x-chebi chebi:28304 assertion.
- drugbank:DB01109 drugbank_vocabulary:x-atc atc:C05BA01 assertion.
- drugbank:DB01109 drugbank_vocabulary:x-ahfs ahfs:20:12.04.16 assertion.
- drugbank:DB01109 drugbank_vocabulary:x-ndc ndc:0009-0268-01 assertion.