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- drugbank:DB01115 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01115 label "Nifedipine [drugbank:DB01115]" assertion.
- drugbank:DB01115 seeAlso nifedip.htm assertion.
- drugbank:DB01115 seeAlso nifedipine.html assertion.
- drugbank:DB01115 seeAlso DB01115 assertion.
- drugbank:DB01115 description "Nifedipine has been formulated as both a long- and short-acting 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nifedipine prevents calcium-dependent myocyte contraction and vasoconstriction. A second proposed mechanism for the drugâs vasodilatory effects involves pH-dependent inhibition of calcium influx via inhibition of smooth muscle carbonic anhydrase. Nifedipine is used to treat hypertension and chronic stable angina." assertion.
- drugbank:DB01115 identifier "drugbank:DB01115" assertion.
- drugbank:DB01115 title "Nifedipine" assertion.
- drugbank:DB01115 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46505103 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-pubchemcompound pubchem.compound:4485 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-chemspider chemspider:4330 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-cas cas:21829-25-4 assertion.
- drugbank:DB01115 drugbank_vocabulary:drugbank-id "APRD00590" assertion.
- drugbank:DB01115 drugbank_vocabulary:drugbank-id "DB01115" assertion.
- drugbank:DB01115 bio2rdf_vocabulary:x-identifiers.org DB01115 assertion.
- drugbank:DB01115 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01115" assertion.
- drugbank:DB01115 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01115 bio2rdf_vocabulary:identifier "DB01115" assertion.
- drugbank:DB01115 drugbank_vocabulary:x-wikipedia wikipedia:Nifedipine assertion.
- drugbank:DB01115 drugbank_vocabulary:x-pharmgkb pharmgkb:PA450631 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-kegg kegg:D00437 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-kegg kegg:C07266 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-dpd dpd:2235898 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-chebi chebi:7565 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-atc atc:C08CA05 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-ahfs ahfs:24:28.08 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-bindingdb bindingdb:50000778 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-ndc ndc:0378-3475-01 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-iuphar iuphar:2514 assertion.
- drugbank:DB01115 drugbank_vocabulary:x-gtp gtp:2514 assertion.