Nanopublications LDF server

Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB01124_nanopub.RATyvfVKh7IorqJR_RIOpkdwMiUDMlJ62x664CPoWIY28#assertion>. }

• drugbank:DB01124 type drugbank_vocabulary:Drug assertion.
• drugbank:DB01124 label "Tolbutamide [drugbank:DB01124]" assertion.
• drugbank:DB01124 seeAlso tolbutamide.html assertion.
• drugbank:DB01124 seeAlso DB01124 assertion.
• drugbank:DB01124 description "Tolbutamide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It is structurally similar to acetohexamide, chlorpropamide and tolazamide and belongs to the sulfonylurea class of insulin secretagogues, which act by stimulating β cells of the pancreas to release insulin. Sulfonylureas increase both basal insulin secretion and meal-stimulated insulin release. Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. Sulfonylureas also increase peripheral glucose utilization, decrease hepatic gluconeogenesis and may increase the number and sensitivity of insulin receptors. Sulfonylureas are associated with weight gain, though less so than insulin. Due to their mechanism of action, sulfonylureas may cause hypoglycemia and require consistent food intake to decrease this risk. The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals. Tolbutamide appears to be metabolized in the liver. Tolbutamide and its metabolites are excreted in urine (75-85%) and feces." assertion.
• drugbank:DB01124 identifier "drugbank:DB01124" assertion.
• drugbank:DB01124 title "Tolbutamide" assertion.
• drugbank:DB01124 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46508421 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-pubchemcompound pubchem.compound:5505 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-chemspider chemspider:5304 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-cas cas:64-77-7 assertion.
• drugbank:DB01124 drugbank_vocabulary:drugbank-id "APRD00267" assertion.
• drugbank:DB01124 drugbank_vocabulary:drugbank-id "DB01124" assertion.
• drugbank:DB01124 bio2rdf_vocabulary:x-identifiers.org DB01124 assertion.
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• drugbank:DB01124 bio2rdf_vocabulary:namespace "drugbank" assertion.
• drugbank:DB01124 bio2rdf_vocabulary:identifier "DB01124" assertion.
• drugbank:DB01124 drugbank_vocabulary:x-wikipedia wikipedia:Tolbutamide assertion.
• drugbank:DB01124 drugbank_vocabulary:x-pharmgkb pharmgkb:PA451718 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-kegg kegg:D00380 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-kegg kegg:C07148 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-dpd dpd:156663 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-chebi chebi:27999 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-atc atc:A10BB03 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-ahfs ahfs:68:20.20 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-ndc ndc:0378-0215-01 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-iuphar iuphar:2415 assertion.
• drugbank:DB01124 drugbank_vocabulary:x-gtp gtp:2415 assertion.