Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB01194_nanopub.RACwVUhQ88h99Vk7l64IFxH6APqBuQXwk5dqU7_icwwvs#assertion>. }
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- drugbank:DB01194 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01194 label "Brinzolamide [drugbank:DB01194]" assertion.
- drugbank:DB01194 seeAlso brinzolamide.htm assertion.
- drugbank:DB01194 seeAlso brinzolamide-drops.html assertion.
- drugbank:DB01194 seeAlso DB01194 assertion.
- drugbank:DB01194 description "Brinzolamide is a highly specific, non-competitive, reversible carbonic anhydrase inhibitor. Carbonic anhydrase (CA) is an enzyme found in many tissues of the body including the eye. It catalyzes the reversible reaction involving the hydration of carbon dioxide and the dehydration of carbonic acid. In humans, carbonic anhydrase exists as a number of isoenzymes, the most active being carbonic anhydrase II (CA-II). Inhibition of carbonic anhydrase in the ciliary processes of the eye decreases aqueous humor secretion, presumably by slowing the formation of bicarbonate ions with subsequent reduction in sodium and fluid transport. The result is a reduction in intraocular pressure. Brinzolamide is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma." assertion.
- drugbank:DB01194 identifier "drugbank:DB01194" assertion.
- drugbank:DB01194 title "Brinzolamide" assertion.
- drugbank:DB01194 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46507071 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-pubchemcompound pubchem.compound:68844 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-pdb pdb:BZU assertion.
- drugbank:DB01194 drugbank_vocabulary:x-chemspider chemspider:62077 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-cas cas:138890-62-7 assertion.
- drugbank:DB01194 drugbank_vocabulary:drugbank-id "APRD00475" assertion.
- drugbank:DB01194 drugbank_vocabulary:drugbank-id "DB01194" assertion.
- drugbank:DB01194 bio2rdf_vocabulary:x-identifiers.org DB01194 assertion.
- drugbank:DB01194 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01194" assertion.
- drugbank:DB01194 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01194 bio2rdf_vocabulary:identifier "DB01194" assertion.
- drugbank:DB01194 drugbank_vocabulary:x-wikipedia wikipedia:Brinzolamide assertion.
- drugbank:DB01194 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164744929 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-kegg kegg:D00652 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-kegg kegg:C07760 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-dpd dpd:2238873 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-chebi chebi:3176 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-atc atc:S01EC04 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-ahfs ahfs:52:10.00 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-bindingdb bindingdb:10885 assertion.
- drugbank:DB01194 drugbank_vocabulary:x-ndc ndc:0065-0275-25 assertion.