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- drugbank:DB01268 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01268 label "Sunitinib [drugbank:DB01268]" assertion.
- drugbank:DB01268 seeAlso sutent.htm assertion.
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- drugbank:DB01268 seeAlso DB01268 assertion.
- drugbank:DB01268 description "Sunitinib is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006. Sunitinib inhibits cellular signaling by targeting multiple RTKs. These include all platelet-derived growth factor receptors (PDGF-R) and vascular endothelial growth factor receptors (VEGF-R). Sunitinib also inhibits KIT (CD117), the RTK that drives the majority of GISTs. In addition, sunitinib inhibits other RTKs including RET, CSF-1R, and flt3." assertion.
- drugbank:DB01268 identifier "drugbank:DB01268" assertion.
- drugbank:DB01268 title "Sunitinib" assertion.
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