Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB01399_nanopub.RATcWJQxFKviifnnf6DunROrrYEJ-ZzR_GPmpx9W0I128#assertion>. }
Showing items 1 to 21 of
21
with 100 items per page.
- drugbank:DB01399 type drugbank_vocabulary:Drug assertion.
- drugbank:DB01399 label "Salsalate [drugbank:DB01399]" assertion.
- drugbank:DB01399 seeAlso salsalate.htm assertion.
- drugbank:DB01399 seeAlso dis1142.shtml assertion.
- drugbank:DB01399 seeAlso salsalate.html assertion.
- drugbank:DB01399 seeAlso DB01399 assertion.
- drugbank:DB01399 description "Salsalate is a nonsteroidal anti-inflammatory agent for oral administration. Salsalate's mode of action as an anti-inflammatory and antirheumatic agent may be due to inhibition of synthesis and release of prostaglandins. The usefulness of salicylic acid, the active in vivo product of salsalate, in the treatment of arthritic disorders has been established. In contrast to aspirin, salsalate causes no greater fecal gastrointestinal blood loss than placebo. Salsalate is readily soluble in the small intestine where it is partially hydrolyzed to two molecules of salicylic acid. A significant portion of the parent compound is absorbed unchanged and undergoes rapid esterase hydrolysis in the body. The parent compound has an elimination half-life of about 1 hour. Salicylic acid (the active metabolite) biotransformation is saturated at anti-inflammatory doses of salsalate. Such capacity limited biotransformation results in an increase in the half-life of salicylic acid from 3.5 to 16 or more hours." assertion.
- drugbank:DB01399 identifier "drugbank:DB01399" assertion.
- drugbank:DB01399 title "Salsalate" assertion.
- drugbank:DB01399 drugbank_vocabulary:x-pubchemsubstance pubchem.substance:46506882 assertion.
- drugbank:DB01399 drugbank_vocabulary:x-pubchemcompound pubchem.compound:5161 assertion.
- drugbank:DB01399 drugbank_vocabulary:x-chemspider chemspider:4977 assertion.
- drugbank:DB01399 drugbank_vocabulary:x-cas cas:552-94-3 assertion.
- drugbank:DB01399 drugbank_vocabulary:drugbank-id "DB01399" assertion.
- drugbank:DB01399 bio2rdf_vocabulary:x-identifiers.org DB01399 assertion.
- drugbank:DB01399 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB01399" assertion.
- drugbank:DB01399 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB01399 bio2rdf_vocabulary:identifier "DB01399" assertion.
- drugbank:DB01399 drugbank_vocabulary:x-pharmgkb pharmgkb:PA164745462 assertion.
- drugbank:DB01399 drugbank_vocabulary:x-kegg kegg:D00428 assertion.
- drugbank:DB01399 drugbank_vocabulary:x-atc atc:N02BA06 assertion.