Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB04991_nanopub.RAThbUPgCqg6TngTWKDEftwJPEkpCKR5F-IBvIap7xK18#assertion>. }
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- drugbank:DB04991 type drugbank_vocabulary:Drug assertion.
- drugbank:DB04991 label "XL784 [drugbank:DB04991]" assertion.
- drugbank:DB04991 seeAlso DB04991 assertion.
- drugbank:DB04991 description "XL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation. XL784 was specifically optimized to be MMP-1 sparing, thus potentially enhancing its safety profile and enabling higher dosing compared with other previously studied metalloprotease inhibitors. Results of single dose Phase I clinical trials of XL784 administered orally to 96 healthy volunteers have demonstrated that XL784 has attractive safety and pharmacokinetic profiles. It is being developed by Exelixis, Inc." assertion.
- drugbank:DB04991 identifier "drugbank:DB04991" assertion.
- drugbank:DB04991 title "XL784" assertion.
- drugbank:DB04991 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB04991 drugbank_vocabulary:drugbank-id "DB04991" assertion.
- drugbank:DB04991 bio2rdf_vocabulary:x-identifiers.org DB04991 assertion.
- drugbank:DB04991 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB04991" assertion.
- drugbank:DB04991 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB04991 bio2rdf_vocabulary:identifier "DB04991" assertion.