Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB05176_nanopub.RAdhcseMQlEp61Y5SgFQUVUFIN58AG-kGmfuUAtgZuZ9E#assertion>. }
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- drugbank:DB05176 type drugbank_vocabulary:Drug assertion.
- drugbank:DB05176 label "CMX001 [drugbank:DB05176]" assertion.
- drugbank:DB05176 seeAlso DB05176 assertion.
- drugbank:DB05176 description "CMX001 is an oral antiviral drug candidate for the treatment of smallpox infections and complications resulting from smallpox vaccine. It is a lipid mimic of cidofovir formed by linking a lipid 3-hexadecyloxy-1-propanol, to the phosphonate group of cidofovir. CMX001 is designed to cross cellular membranes by passive diffusion (vida supra, Phospholipid Mimics Designed to Facilitate Uptake in the Small Intestine). Uptake by this mechanism should be more efficient and lead to a more rapid accumulation of cidofovir in the cytoplasm of the target cell. Once it has reached the cytoplasm, CDV is phosphorylated by host cell nucleoside kinases to form the active antiviral agent cidofovir diphosphate." assertion.
- drugbank:DB05176 identifier "drugbank:DB05176" assertion.
- drugbank:DB05176 title "CMX001" assertion.
- drugbank:DB05176 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB05176 drugbank_vocabulary:drugbank-id "DB05176" assertion.
- drugbank:DB05176 bio2rdf_vocabulary:x-identifiers.org DB05176 assertion.
- drugbank:DB05176 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB05176" assertion.
- drugbank:DB05176 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB05176 bio2rdf_vocabulary:identifier "DB05176" assertion.