Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB05200_nanopub.RA7PiBeS0Ka1zGjixgfG-oUnP0EPsNEZS_gwdA1zfGp9U#assertion>. }
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- drugbank:DB05200 type drugbank_vocabulary:Drug assertion.
- drugbank:DB05200 label "AT2220 [drugbank:DB05200]" assertion.
- drugbank:DB05200 seeAlso DB05200 assertion.
- drugbank:DB05200 description "AT2220 is an experimental, oral therapy for the treatment of Pompe disease and belongs to a class of molecules known as pharmacological chaperones. It is a small molecule designed to act as a pharmacological chaperone that specifically binds, stabilizes, and facilitates the proper folding and trafficking of α-glucosidase (GAA). GAA to the lysosome, where it can perform its normal function. AT2220 has been shown to increase GAA activity in cell lines derived from Pompe patients and in transfected cells expressing misfolded forms of GAA." assertion.
- drugbank:DB05200 identifier "drugbank:DB05200" assertion.
- drugbank:DB05200 title "AT2220" assertion.
- drugbank:DB05200 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB05200 drugbank_vocabulary:drugbank-id "DB05200" assertion.
- drugbank:DB05200 bio2rdf_vocabulary:x-identifiers.org DB05200 assertion.
- drugbank:DB05200 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB05200" assertion.
- drugbank:DB05200 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB05200 bio2rdf_vocabulary:identifier "DB05200" assertion.