Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB05447_nanopub.RAyee4IXURTxoepzbaX-LE8vrptasaJu0bc8W8pKGFNtk#assertion>. }
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- drugbank:DB05447 type drugbank_vocabulary:Drug assertion.
- drugbank:DB05447 label "AVI-4557 [drugbank:DB05447]" assertion.
- drugbank:DB05447 seeAlso DB05447 assertion.
- drugbank:DB05447 description "AVI-4557 is an oral antisense compound that selectively inhibits the metabolic enzyme cytochrome P450 3A4 (CYP), a liver enzyme responsible for the metabolism or breakdown of approximately half of currently marketed drugs. Studies indicate that AVI-4557 can successfully reduce the rate of metabolism for certain drugs, therefore allowing greater and longer availability of the drug in the patient's system through a decrease in clearance and an increase in maximal blood concentration (Cmax). AVI-4557 is therefore indicated to limit toxicity for patients receiving highly-toxic therapeutic drugs for treatment of anxiety, cancer, and a number of other serious conditions." assertion.
- drugbank:DB05447 identifier "drugbank:DB05447" assertion.
- drugbank:DB05447 title "AVI-4557" assertion.
- drugbank:DB05447 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB05447 drugbank_vocabulary:drugbank-id "DB05447" assertion.
- drugbank:DB05447 bio2rdf_vocabulary:x-identifiers.org DB05447 assertion.
- drugbank:DB05447 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB05447" assertion.
- drugbank:DB05447 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB05447 bio2rdf_vocabulary:identifier "DB05447" assertion.