Matches in Nanopublications for { ?s ?p ?o <http://bio2rdf.org/drugbank:DB05463_nanopub.RAKQcABa5ovsWRY0GBf-afUuDajygcV8WPzZtDLen36uw#assertion>. }
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- drugbank:DB05463 type drugbank_vocabulary:Drug assertion.
- drugbank:DB05463 label "ISS-1018 [drugbank:DB05463]" assertion.
- drugbank:DB05463 seeAlso DB05463 assertion.
- drugbank:DB05463 description "ISS 1018 is a short, synthetic, unmethylated CpG oligodeoxynucleotide (CpG ODN) with immunostimulatory activity. ISS 1018 signals through Toll-like receptor 9 (TLR9) to induce the production of immunoglobulin by B cells and interferon (IFN) -alpha, IFN-beta, interleukin-12 (IL-12), and tumor necrosis factor - alpha (TNF-alpha) by plasmacytoid dendritic cells (pDC). ISS 1018 CpG ODN promotes antigen presentation and co-stimulatory molecule expression. ISS 1018 is currently being investigated in combination with HBsAg vaccine as a prophylactic treatment for to prevent Hepatitis B in adults. It is also being investigated in combination with rituximab for treatment of b-cell or non-hodgkin's lymphoma." assertion.
- drugbank:DB05463 identifier "drugbank:DB05463" assertion.
- drugbank:DB05463 title "ISS-1018" assertion.
- drugbank:DB05463 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB05463 drugbank_vocabulary:drugbank-id "DB05463" assertion.
- drugbank:DB05463 bio2rdf_vocabulary:x-identifiers.org DB05463 assertion.
- drugbank:DB05463 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB05463" assertion.
- drugbank:DB05463 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB05463 bio2rdf_vocabulary:identifier "DB05463" assertion.