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- drugbank:DB05481 type drugbank_vocabulary:Drug assertion.
- drugbank:DB05481 label "Recombinant alpha 1-antitrypsin [drugbank:DB05481]" assertion.
- drugbank:DB05481 seeAlso DB05481 assertion.
- drugbank:DB05481 description "Alpha 1-antitrypsin is a glycoprotein primarily produced by hepatocytes, and to a lesser extent, immune system cells. Recombinant alpha 1-antitrypsin (rAAT) is produced from yeast, which unlike commercially available forms of plasma-derived AAT, eliminates the risk associated with blood-borne infectious agents and allows for a increased manufacturing. rAAT belongs to a family of structurally-related proteins classified as serine protease inhibitors or SERPINS, which are known to inhibit several proteases including trypsin, cathepsin G, thrombin, tissue kallikrein, as well as neutrophil elastase. The proteinase/antiproteinase balance is believed to be important for maintaining healthy skin. The rAAT topical gel (Dermolastinâ¢) is indicated for patients with atopic dermatitis and psoriasis. The company has indicated that other formulations for gastroenterological and urological indications will also be developed." assertion.
- drugbank:DB05481 identifier "drugbank:DB05481" assertion.
- drugbank:DB05481 title "Recombinant alpha 1-antitrypsin" assertion.
- drugbank:DB05481 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB05481 drugbank_vocabulary:drugbank-id "DB05481" assertion.
- drugbank:DB05481 bio2rdf_vocabulary:x-identifiers.org DB05481 assertion.
- drugbank:DB05481 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB05481" assertion.
- drugbank:DB05481 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB05481 bio2rdf_vocabulary:identifier "DB05481" assertion.