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- drugbank:DB05489 type drugbank_vocabulary:Drug assertion.
- drugbank:DB05489 label "ACA 125 [drugbank:DB05489]" assertion.
- drugbank:DB05489 seeAlso DB05489 assertion.
- drugbank:DB05489 description "An IgG1 murine monoclonal anti-idiotype antibody (Ab2), ACA-125, was developed to bind to anti-CA 125 antibodies. ACA-125 mimics the tumor-associated antigen CA-125, which can be detected in about 80% of ovarian carcinomas. This new concept of oncological immunotherapy consists of an attempt to trigger the immune system of the host to respond against tumor cells. Antiidiotypic antibodies bearing the internal image of an antigen expressed on the surface of the tumor are suited to this approach. To create ACA-125, a hybridoma cell was adapted to serum-free medium and antibody was produced in a hollow fiber cell culture system. Positive clinical results are now being reported." assertion.
- drugbank:DB05489 identifier "drugbank:DB05489" assertion.
- drugbank:DB05489 title "ACA 125" assertion.
- drugbank:DB05489 drugbank_vocabulary:x-cas cas: assertion.
- drugbank:DB05489 drugbank_vocabulary:drugbank-id "DB05489" assertion.
- drugbank:DB05489 bio2rdf_vocabulary:x-identifiers.org DB05489 assertion.
- drugbank:DB05489 bio2rdf_vocabulary:uri "http://bio2rdf.org/drugbank:DB05489" assertion.
- drugbank:DB05489 bio2rdf_vocabulary:namespace "drugbank" assertion.
- drugbank:DB05489 bio2rdf_vocabulary:identifier "DB05489" assertion.