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- assertion asSentence Pigment+eppitheliuim+derived+factor+%28PEDF%29+plays+a+protective+role+against+tubular+injury+in+diabetic+nephropathy+by+attenuating+the+deleterious+effects+of+advanced+glycation+end+products+%28AGEs%29+via+down-regulation+of+RAGE+expression. assertion.
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