Nanopublications

Matches in Nanopublications for { ?s ?p ?o <http://purl.org/np/RAYOsXf6wLjW5R7f7Sjg4bjbYzKnxF5hS7EPHa73sCnP4#assertion>. }

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has_phenotype label "has phenotype - holds between a biological entity and a phenotype, where a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). In SNOMEDCT, disorders with keyword 'characterized by' should translate into this predicate." assertion.
treats label "treats - holds between a therapeutic procedure or chemical entity and a disease or phenotypic feature that it is used to treat" assertion.
interacts_with label "interacts with - holds between any two entities that directly or indirectly interact with each other" assertion.
correlated_with label "correlated with - A relationship that holds between two concepts represented by variables for which a statistical dependence is demonstrated using a correlation analysis method." assertion.
affects label "affects - describes an entity that has a direct affect on the state or quality of another existing entity. Use of the 'affects' predicate implies that the affected entity already exists, unlike predicates such as 'affects risk for' and 'prevents, where the outcome is something that may or may not come to be." assertion.
treated_by label "treated by - holds between a disease or phenotypic feature and a therapeutic process or chemical entity that is used to treat the condition" assertion.
associated_with label "associated with - Expresses a relationship between two named things where the relationship is typically generated statistically (though not in all cases), and is weaker than its child, 'correlated with', but stronger than its parent, 'related to'. This relationship holds between two concepts represented by variables for which a statistical dependence is demonstrated. E.g. the statement “Atrial Fibrillation (Afib) is associated with Myocardial Infarction (MI)” asserts that having Afib is not statistically independent from whether a patient will also have MI. Note that in Translator associations, the subject and object concepts may map exactly to the statistical variables, or represent related entities for which the variables serve as proxies in an Association (e.g. diseases, chemical entities or processes)." assertion.
ameliorates label "ameliorates - A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure, clinical intervention) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition." assertion.
prevents label "prevents - holds between an entity whose application or use reduces the likelihood of a potential outcome. Typically used to associate a chemical entity, exposure, activity, or medical intervention that can prevent the onset a disease or phenotypic feature." assertion.
predisposes label "predisposes - holds between two entities where exposure to one entity increases the chance of developing the other" assertion.
positively_correlated_with label "positively correlated with - A relationship that holds between two concepts represented by variables for which a statistical correlation is demonstrated, wherein variable values move together in the same direction (i.e. increased in one or presence of one correlates with an increase or presence of the other)." assertion.
xenologous_to label "xenologous to - a homology relationship characterized by an interspecies (horizontal) transfer since the common ancestor." assertion.
translation_of label "translation of - inverse of translates to" assertion.
translates_to label "translates to - x (amino acid chain/polypeptide) is the ribosomal translation of y (transcript) if and only if a ribosome reads y (transcript) through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces x (amino acid chain/polypeptide)" assertion.
transcribed_to label "transcribed to - inverse of transcribed from" assertion.
transcribed_from label "transcribed from - x is transcribed from y if and only if x is synthesized from template y" assertion.
temporally_related_to label "temporally related to - holds between two entities with a temporal relationship" assertion.
target_for label "target for - A gene is a target of a disease when its products are druggable and when a drug interaction with the gene product could have a therapeutic effect" assertion.
similar_to label "similar to - holds between an entity and some other entity with similar features." assertion.
response_affected_by label "response affected by - holds between two chemical entities where the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) of one is affected by the action of the other." assertion.
related_to label "related to - A relationship that is asserted between two named things" assertion.
regulates label "regulates - A more specific form of affects, that implies the effect results from a biologically evolved control mechanism. Gene-affects-gene relationships will (almost) always involve regulation. Exogenous/environmental chemical-affects-gene relationships are not cases of regulation in this definition. Instead these would be captured using the 'affects' predicate, or possibly one of the 'interacts with' predicates depending on the nature of the interaction." assertion.
produces label "produces - holds between a material entity and a product that is generated through the intentional actions or functioning of the material entity" assertion.
prevented_by label "prevented by - holds between a potential outcome of which the likelihood was reduced by the application or use of an entity." assertion.
precedes label "precedes - holds between two processes, where one completes before the other begins" assertion.
preceded_by label "preceded by - holds between two processes, where the other is completed before the one begins" assertion.
physically_interacts_with label "physically interacts with - holds between two entities that make physical contact as part of some interaction. does not imply a causal relationship." assertion.
participates_in label "participates in - holds between a continuant and a process, where the continuant is somehow involved in the process" assertion.
part_of label "part of - holds between parts and wholes (material entities or processes)" assertion.
paralogous_to label "paralogous to - a homology relationship that holds between entities (typically genes) that diverged after a duplication event." assertion.
overlaps label "overlaps - holds between entities that overlap in their extents (materials or processes)" assertion.
orthologous_to label "orthologous to - a homology relationship between entities (typically genes) that diverged after a speciation event." assertion.
opposite_of label "opposite of - x is the opposite of y if there exists some distance metric M, and there exists no z such as M(x,z) <= M(x,y) or M(y,z) <= M(y,x). (This description is from RO. Needs to be rephrased)." assertion.
occurs_together_in_literature_with label "occurs together in literature with - holds between two entities where their co-occurrence is correlated by counts of publications in which both occur, using some threshold of occurrence as defined by the edge provider." assertion.
occurs_in label "occurs in - holds between a process and a material entity or site within which the process occurs" assertion.
nutrient_of label "nutrient of - holds between a one or more chemical entities present in food, irrespective of nutritional value (i.e. could also be a contaminant or additive)" assertion.
negatively_correlated_with label "negatively correlated with - A relationship that holds between two concepts represented by variables for which a statistical correlation is demonstrated, wherein variable values move in opposite directions (i.e. increased in one or presence of one correlates with a decrease or absence of the other)." assertion.
molecular_activity_has_output label "molecular activity has output - A chemical entity that is the output for the reaction" assertion.
molecular_activity_has_input label "molecular activity has input - A chemical entity that is the input for the reaction" assertion.
molecular_activity_enabled_by label "molecular activity enabled by - The gene product, gene, or complex that catalyzes the reaction" assertion.
model_of label "model of - holds between a thing and some other thing it approximates for purposes of scientific study, in virtue of its exhibiting similar features of the studied entity." assertion.
mentions label "mentions - refers to is a relation between one information content entity and the named thing that it makes reference to." assertion.
mentioned_by label "mentioned by - refers to is a relation between one named thing and the information content entity that it makes reference to." assertion.
member_of label "member of - Defines a mereological relation between a item and a collection." assertion.
manifestation_of label "manifestation of - that part of a phenomenon which is directly observable or visibly expressed, or which gives evidence to the underlying process; used in SemMedDB for linking things like dysfunctions and processes to some disease or syndrome" assertion.
location_of label "location of - holds between material entity or site and a material entity that is located within it (but not considered a part of it)" assertion.
located_in label "located in - holds between a material entity and a material entity or site within which it is located (but of which it is not considered a part)" assertion.
likelihood_associated_with label "likelihood associated with - " assertion.
is_synonymous_variant_of label "is synonymous variant of - holds between a sequence variant and a gene, such the sequence variant is in the coding sequence of the gene, but results in the same amino acid sequence" assertion.
is_splice_site_variant_of label "is splice site variant of - holds between a sequence variant and a gene, such the sequence variant is in the canonical splice site of one of the gene's exons." assertion.
is_sequence_variant_of label "is sequence variant of - holds between a sequence variant and a nucleic acid entity" assertion.
is_nonsense_variant_of label "is nonsense variant of - holds between a sequence variant and a gene, such the sequence variant results in a premature stop codon" assertion.
is_non_coding_variant_of label "is non coding variant of - holds between a sequence variant and a gene, where the variant does not affect the coding sequence" assertion.
is_nearby_variant_of label "is nearby variant of - holds between a sequence variant and a gene sequence that the variant is genomically close to." assertion.
is_missense_variant_of label "is missense variant of - holds between a gene and a sequence variant, such the sequence variant results in a different amino acid sequence but where the length is preserved." assertion.
is_metabolite_of label "is metabolite of - holds between two molecular entities in which the first one is derived from the second one as a product of metabolism" assertion.
is_frameshift_variant_of label "is frameshift variant of - holds between a sequence variant and a gene, such the sequence variant causes a disruption of the translational reading frame, because the number of nucleotides inserted or deleted is not a multiple of three." assertion.
is_excipient_of label "is excipient of - holds between a molecular entity and a drug in which the former is a part of the latter, and is a biologically inactive component" assertion.
is_active_ingredient_of label "is active ingredient of - holds between a molecular entity and a drug, in which the former is a part of the latter, and is a biologically active component" assertion.
increases_response_to label "increases response to - holds between two chemical entities where the action or effect of one increases the susceptibility of a biological entity or system (e.g. an organism, cell, cellular component, macromolecular machine mixin, biological or pathological process) to the other" assertion.
increases_amount_or_activity_of label "increases amount or activity of - A grouping mixin to help with searching for all the predicates that increase the amount or activity of the object." assertion.
increased_likelihood_associated_with label "increased likelihood associated with - " assertion.
in_taxon label "in taxon - connects an entity to its taxonomic classification. Only certain kinds of entities can be taxonomically classified; see 'thing with taxon'" assertion.
in_pathway_with label "in pathway with - holds between two genes or gene products that are part of in the same biological pathway" assertion.
in_linkage_disequilibrium_with label "in linkage disequilibrium with - holds between two sequence variants, the presence of which are correlated in a population" assertion.
in_complex_with label "in complex with - holds between two genes or gene products that are part of (or code for products that are part of) in the same macromolecular complex" assertion.
in_cell_population_with label "in cell population with - holds between two genes or gene products that are expressed in the same cell type or population" assertion.
homologous_to label "homologous to - holds between two biological entities that have common evolutionary origin" assertion.
has_variant_part label "has variant part - holds between a nucleic acid entity and a nucleic acid entity that is a sub-component of it" assertion.
has_side_effect label "has side effect - An unintended, but predictable, secondary effect shown to be correlated with a therapeutic agent, drug or treatment. Side effects happen at normal, recommended doses or treatments, and are unrelated to the intended purpose of the medication." assertion.
has_sequence_location label "has sequence location - holds between two nucleic acid entities when the subject can be localized in sequence coordinates on the object. For example, between an exon and a chromosome/contig." assertion.
has_plasma_membrane_part label "has plasma membrane part - Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part." assertion.
has_participant label "has participant - holds between a process and a continuant, where the continuant is somehow involved in the process" assertion.
has_part label "has part - holds between wholes and their parts (material entities or processes)" assertion.
has_output label "has output - holds between a process and a continuant, where the continuant is an output of the process" assertion.
has_nutrient label "has nutrient - one or more nutrients which are growth factors for a living organism" assertion.
has_not_completed label "has not completed - holds between an entity and a process that the entity is capable of, but has not completed" assertion.
has_molecular_consequence label "has molecular consequence - connects a sequence variant to a class describing the molecular consequence. E.g. SO:0001583" assertion.
has_mode_of_inheritance label "has mode of inheritance - Relates a disease or phenotypic feature to its observed genetic segregation and assumed associated underlying DNA manifestation (i.e. autosomal, sex or mitochondrial chromosome)." assertion.
has_metabolite label "has metabolite - holds between two molecular entities in which the second one is derived from the first one as a product of metabolism" assertion.
has_member label "has member - Defines a mereological relation between a collection and an item." assertion.
has_input label "has input - holds between a process and a continuant, where the continuant is an input into the process" assertion.
has_gene_product label "has gene product - holds between a gene and a transcribed and/or translated product generated from it" assertion.
has_food_component label "has food component - holds between food and one or more chemical entities composing it, irrespective of nutritional value (i.e. could also be a contaminant or additive)" assertion.
has_excipient label "has excipient - holds between a drug and a molecular entities in which the latter is a part of the former, and is a biologically inactive component" assertion.
has_completed label "has completed - holds between an entity and a process that the entity is capable of and has completed" assertion.
has_chemical_role label "has chemical role - A role is particular behaviour which a chemical entity may exhibit." assertion.
has_biomarker label "has biomarker - holds between a disease or phenotypic feature and a measurable chemical entity that is used as an indicator of the presence or state of the disease or feature. # metabolite" assertion.
has_adverse_event label "has adverse event - An untoward medical occurrence in a patient or clinical investigation subject that happens during treatment with a therapeutic agent. Adverse events may be caused by something other than the drug or therapy being given and may include abnormal laboratory finding, symptoms, or diseases temporally associated with the treatment, whether or not considered related to the treatment. Adverse events are unintended effects that occur when a medication is administered correctly." assertion.
has_active_ingredient label "has active ingredient - holds between a drug and a molecular entity in which the latter is a part of the former, and is a biologically active component" assertion.
genetically_interacts_with label "genetically interacts with - holds between two genes whose phenotypic effects are dependent on each other in some way - such that their combined phenotypic effects are the result of some interaction between the activity of their gene products. Examples include epistasis and synthetic lethality." assertion.
genetic_neighborhood_of label "genetic neighborhood of - holds between two genes located nearby one another on a chromosome. " assertion.
genetic_association label "genetic association - Co-occurrence of a certain allele of a genetic marker and the phenotype of interest in the same individuals at above-chance level" assertion.
gene_product_of label "gene product of - definition x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of thatf process is either y or something that is ribosomally translated from x" assertion.
gene_fusion_with label "gene fusion with - holds between two independent genes that have fused through translocation, interstitial deletion, or chromosomal inversion to form a new, hybrid gene. Fusion genes are often implicated in various neoplasms and cancers." assertion.
gene_associated_with_condition label "gene associated with condition - holds between a gene and a disease or phenotypic feature that the gene or its alleles/products may influence, contribute to, or correlate with" assertion.
food_component_of label "food component of - holds between a one or more chemical entities present in food, irrespective of nutritional value (i.e. could also be a contaminant or additive)" assertion.
expresses label "expresses - holds between an anatomical entity and gene or gene product that is expressed there" assertion.
expressed_in label "expressed in - holds between a gene or gene product and an anatomical entity in which it is expressed" assertion.
exacerbates label "exacerbates - A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition." assertion.