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- source_evidence_literature type ECO_0000212 NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_provenance.
- NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_assertion wasGeneratedBy ECO_0000203 NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_provenance.
- NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_assertion wasDerivedFrom befree-20140225 NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_provenance.
- NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_assertion SIO_000772 9746856 NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_provenance.
- NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_assertion evidence source_evidence_literature NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_provenance.
- NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_assertion description "[Universally binding nucleosomal epitopes are productively recognized by autoreactive T cells by binding to the T-cell receptor-alpha chain; (b) circulating T cells from patients with lupus commonly display a deficiency of the T-cell receptor zeta chain, and upon ligation of their cell-surface antigen receptor overproduce tyrosine phosphorylated proteins; (c) lupus and lupus nephritis are associated with a low-binding FcgammaRIIIA (CD16) polymorphism that crosses ethnic barriers; (d) the pathogenetic role of the cytokine interleukin-10 is expanding, because it is reportedly overproduced not only by cells from lupus patients but also by cells from their healthy relatives, and its overproduction in vitro is correlated with increased apoptotic cell death and with lymphopenia.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_provenance.
- befree-20140225 importedOn "2014-02-25" NP510461.RAPsmHpQWrp3lB50GXMcrRWzm0ZMuMx6jyAnMGJbzZhVI130_provenance.