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- source_evidence_literature type ECO_0000212 NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_provenance.
- befree-20150227 importedOn "2015-02-27" NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_provenance.
- NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_assertion wasGeneratedBy ECO_0000203 NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_provenance.
- NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_assertion wasDerivedFrom befree-20150227 NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_provenance.
- NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_assertion SIO_000772 16949064 NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_provenance.
- NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_assertion evidence source_evidence_literature NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_provenance.
- NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_assertion description "[The initial study found that urine concentrations of the metabolites 1,2-dihydroxy-4-(acetyl) butane (M1) and 1-dihydroxy-2-(N-acetylcysteinyl)-3-butene (M2) and blood concentrations of the hemoglobin adducts N-[2-hydroxy-3-butenyl] valine (HB-Val) and N-[2,3,4-trihydroxy-butyl] valine (THB-Val) constitute excellent biomarkers of exposure, both being highly correlated with BD exposure levels, and that GST genotypes modulate at least one metabolic pathway, but that irreversible genotoxic effects such as chromosome aberrations and HPRT gene mutations are neither associated with BD exposure levels nor with worker genotypes (GST [glutathione-S-transferase]-M1, GSTT1, CYP2E1 (5' promoter), CYP2E1 (intron 6), EH [epoxide hydrolase] 113, EH139, ADH [alcohol dehydrogenase]2 and ADH3).]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP342792.RAYIAM-HYyAytCk3MluTJCxnDDWVxlChzgtsA2mgS-XHs130_provenance.