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- source_evidence_literature type ECO_0000212 NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_provenance.
- befree-2016 importedOn "2016-02-19" NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_provenance.
- NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_assertion wasGeneratedBy ECO_0000203 NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_provenance.
- NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_assertion wasDerivedFrom befree-2016 NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_provenance.
- NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_assertion SIO_000772 15929167 NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_provenance.
- NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_assertion evidence source_evidence_literature NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_provenance.
- NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_assertion description "[The current studies showed that: (1) incubation of CagA-positive H pylori with MKN-45 cells significantly promotes gastric cancer cells invasion, and this effect is attenuated by pre-treatment with NS-398, a COX-2 inhibitor, or PDTC, a nuclear factor kappaB (NF-kappaB) inhibitor; (2) the induction of MKN-45 cells invasion by H pylori is associated with increases in COX-2, MMP-9, and VEGF protein expression, and co-incubation of NS-398 or PDTC significantly reduces these effects; (3) H pylori infection transactivates COX-2 promoter activity and increases the binding of NF-kappaB to this promoter.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP497344.RAdtZObtw-4vmrlKe5dAvJ-I31mUSQFC6ITNvs-j99neM130_provenance.