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- source_evidence_literature type ECO_0000212 NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_provenance.
- source_evidence_literature label "DisGeNET evidence - LITERATURE" NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_provenance.
- source_evidence_literature comment "Gene-disease associations inferred from text-mining the literature." NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_provenance.
- befree-2016 importedOn "2016-02-19" NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_provenance.
- NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_assertion wasGeneratedBy ECO_0000203 NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_provenance.
- NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_assertion wasDerivedFrom befree-2016 NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_provenance.
- NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_assertion SIO_000772 17079443 NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_provenance.
- NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_assertion evidence source_evidence_literature NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_provenance.
- NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_assertion description "[In contrast, inactivation of pRb, the key component of the pathway, activated the DDR in cultured human or mouse cells, analogous to elevated cyclin E. These results highlight differential effect of diverse oncogenic events on driving the 'cancer cell cycles' and their ability to deregulate the replication-driving CDK2 kinase and to alarm the DDR as a potential anticancer barrier in accordance with their hierarchical positions along the retinoblastoma pathway.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine." NP577329.RA0hi3IgTNxKcmH8FPhKAxfqaVC2OYBBadx64xmaYkUSw130_provenance.