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- _5 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "1.4" provenance.
- large_corpus.bel authoredBy _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _4 provenance.
- assertion hadPrimarySource 9844018 provenance.
- _4 wasQuotedFrom 9844018 provenance.
- _4 value "We demonstrate that p90rsk-1, p90rsk-2, gsk-3, ERK-2, and p70S6K kinases are components of the protein translation complex. gsk-3b is a constitutively active kinase and phosphorylation by p90rsk inhibits its kinase activity (47). One of the known gsk-3 substrates is the translation initiation factor eIF2B. Phosphorylation of this translation initiation factor decreases translation (49, 50). Thus, inhibition of gsk-3b by p90rsk phosphorylation would result in a rapid increase in translation. " provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.