Matches in Nanopublications for { ?s ?p ?o <http://www.tkuhn.ch/bel2nanopub/RA18OsGnsvSyZ0K5fmQa5J_2kEfZ87vzVtmdJ7ZiiriS8#provenance>. }
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- _6 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "1.4" provenance.
- large_corpus.bel authoredBy _6 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion hadPrimarySource 15863030 provenance.
- _5 wasQuotedFrom 15863030 provenance.
- _5 value " PLC gamma is phosphorylated by activated FGFR, resulting in PLC gamma activation, stimulation of phosphatidyl inositol hydrolysis and generation of two second messengers, diacylglycerol and inositol (1,4,5) P3. Tyrosine phosphorylation of PLCgamma by FGFR4 is weaker than that seen by other isoforms of FGFR.Three tyrosine residues in PLC gamma have been identified as sites of receptor tyrosine kinase phosphorylation. Mutagenesis indicates that the phosphorylation at Tyr 783 is essential for IP3 formation, phosphorylation of Tyr 771 is dispensable, and phosphorylation of Tyr 1254 is necessary to achieve maximal IP3 formation. " provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.