Matches in Nanopublications for { ?s ?p ?o <http://www.tkuhn.ch/bel2nanopub/RA3d6BQNhjMkeCl655I9CvO7h9vFf8oRqN-A1e-Rbxbu8#provenance>. }
Showing items 1 to 11 of
11
with 100 items per page.
- _8 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _8 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _7 provenance.
- assertion hadPrimarySource 17463250 provenance.
- _7 wasQuotedFrom 17463250 provenance.
- _7 value "To investigate how MET activates ERBB3 tyrosine phosphorylation, we first expressed ERBB3 alone or in combination with MET in Chinese hamster ovary (CHO) cells, which normally do not express detectable levels of EGFR, ERBB2, or ERBB3. Coexpression of MET and ERBB3 resulted in marked phosphorylation of ERBB3 (Fig. 3D). This phosphorylation could be blocked with PHA-665752 but not with high concentrations of gefitinib (3 mM), lapatinib (3 mM) or the SRC family kinase inhibitor PP2 (10 mM). In addition, phosphorylated ERBB3 coimmunoprecipitated with p85 in a MET kinase–dependent manner (fig. S6). " provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.