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- _6 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _6 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion hadPrimarySource 16627617 provenance.
- _5 wasQuotedFrom 16627617 provenance.
- _5 value "The connection between TOR and PI3K is revealed by the observation that Akt, which is activated by the PI3K pathway, phosphorylates and inhibits TSC2 (19?21). Furthermore, the understanding of the molecular function of TSC1/2 in regulating TORC1 was significantly advanced when Ras homology enriched in brain (Rheb) was identified as a key component acting downstream of TSC1/2 and upstream of TOR (22?27)... Therefore, a signaling pathway of PI3K-Akt-TSC2-Rheb-TORC1 has been proposed. (from full text)" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.