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- _5 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _4 provenance.
- assertion hadPrimarySource 19962312 provenance.
- _4 wasQuotedFrom 19962312 provenance.
- _4 value "We show that, upon DNA damage, RASSF1A is phosphorylated by ATM on Ser131 and is involved in the activation of both MST2 and LATS1, leading to the stabilization of p73....As shown previously, expression of RASSF1A enhances the stability of p73 [7], but this stabilization was further enhanced when combined with DNA damage (Figure 4C, left). In agreement with a role for the ATM phosphorylation site in pathway signaling, RASSF1A-S131A blocked the stabilization of p73 in response to cisplatin-mediated DNA damage (Figure 4C, right)." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.