Nanopublications

Matches in Nanopublications for { ?s ?p ?o <http://www.tkuhn.ch/bel2nanopub/RA6S5dmclYyZhENnVX57nBCqtEGPHjbOQFHNGMUIZSQIE#provenance>. }

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_5 label "Selventa" provenance.
large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
large_corpus.bel description "Approximately 61,000 statements." provenance.
large_corpus.bel version "20131211" provenance.
large_corpus.bel authoredBy _5 provenance.
assertion wasDerivedFrom large_corpus.bel provenance.
assertion wasDerivedFrom _4 provenance.
assertion hadPrimarySource 16601225 provenance.
_4 wasQuotedFrom 16601225 provenance.
_4 value "Thrombin-induced NAD(P)H oxidase regulated expression of another 22 genes that belong to various functional groups at the G1/S transition point (supplemental Table II). Then we compared the differences in gene expression profiles of cell types with functional and impaired NAD(P)H oxidase. Microarray data analyzed with multiclass SAM (2000 permutations and value of 0.245 corresponding to a FDR of 5.1%) identified 28 genes as most significantly differentially regulated (supplemental Figure IB) in response to thrombin treatment. Real-time RT-PCR analysis confirmed the transcriptional pattern of 22 of 28 genes identified using SAM (78.5%). Among these 22 genes, 11 were upregulated and 11 were downregulated. These genes fall into various functional groups: 5 genes encoded proteins involved in transcriptional regulation; 5 encoded signal transduction proteins; 5 encoded metabolic pathway proteins; 1 gene encoded electron and ion transport proteins; and another 6 encoded extracellular matrix and cytoskeletal proteins (supplemental Table II)." provenance.