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- _6 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _6 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion hadPrimarySource 14580340 provenance.
- _5 wasQuotedFrom 14580340 provenance.
- _5 value "In metabolically labelled Ntva-RA cells the Akt signalling was therapeutically blocked to see the effect on synthesis of VEGF. The effect of Akt blockade on the normalised polysome RNA values for VEGF frequently resulted in a shift of mRNA away from the polysome fraction and correlated well with reduction in protein synthesis. The effects on polysome recruitment occur within 2 h and at this point the effects on transcription are minimal suggesting that the transduction precedes the transcriptional effects due to the fact that 20% of the mRNA that are differentially recruited to ribosomes at 2 h encode transcription factors." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.