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- _5 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "1.4" provenance.
- large_corpus.bel authoredBy _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _4 provenance.
- assertion hadPrimarySource 20724658 provenance.
- _4 wasQuotedFrom 20724658 provenance.
- _4 value "ROS signals can amplify AKT signaling cascades in the forward direction through transient oxidative inactivation of the phosphatase and tensin homolog (PTEN) and other phosphatases that oppose AKT phosphorylation (21). Accordingly, we utilized the phosphorylation status of AKT as a central marker for signal transduction that can be modulated by H2O2. Accordingly, we utilized the phosphorylation status of AKT as a central marker for signal transduction that can be modulated by H2O2. Initial experiments tested the direct effects of H2O2 on AKT phosphorylation. Serum-starved control HeLa cells do not exhibit increases in pAKT/AKT ratios upon addition of H2O2 (Fig. 2D)." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.