Matches in Nanopublications for { ?s ?p ?o <http://www.tkuhn.ch/bel2nanopub/RAE7FhkIpqJlKR9qwq7Kj6oLYH4RFVIrhRv2HQfuCWbtY#provenance>. }
Showing items 1 to 11 of
11
with 100 items per page.
- _7 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "1.4" provenance.
- large_corpus.bel authoredBy _7 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _6 provenance.
- assertion hadPrimarySource 11864996 provenance.
- _6 wasQuotedFrom 11864996 provenance.
- _6 value "To investigate the normal intracellular distribution of 14-3-3 proteins and their ligands, U2OS cells were immunostained with a polyclonal antibody that recognizes all 14-3-3 isotypes (pan-14-3-3) or with a monoclonal antibody generated against the 14-3-3sigma isotype (Fig. 1 A). Upon growth factor stimulation, Akt is activated, directly phosphorylating FKHRL1 at T32 and S253, and to a lesser extent at S315, and resulting in FKHRL1 relocalization from the nucleus to the cytoplasm .... Similar AKT-dependent changes in subcellular localization have also been observed for the additional FKHRL1 human homologs AFX and FKHR.... Phosphorylation at T32 and S253 causes FKHRL1 to bind to 14-3-3, suggesting that the interaction between FKHRL1 and 14-3-3 may play an important role in regulating the subcellular localization of the complex." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.