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- _7 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- _5 title "Landes Bioscience - TIMPs in Tumor Growth and Invasion" provenance.
- _5 type "Other" provenance.
- _5 identifier "Landes Bioscience - TIMPs in Tumor Growth and Invasion" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _7 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _6 provenance.
- assertion hadPrimarySource _5 provenance.
- _6 wasQuotedFrom _5 provenance.
- _6 value "TIMP-3 expressing stable colon carcinoma cell lines display reduced tumor growth, 199 and in these cells TIMP-3 overexpression resulted in apoptosis through stabilization of TNF-a receptors on the cell surface. 200 This suggests that individual TIMPs may modulate the levels of death proteins from the cell surface, as demonstrated by findings that shedding of FAS from the cell surface is mediated by MMP-induced cleavage and is inhibited by synthetic MMP inhibitors. 201" provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.