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- _7 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "1.4" provenance.
- large_corpus.bel authoredBy _7 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _6 provenance.
- assertion hadPrimarySource 15231654 provenance.
- _6 wasQuotedFrom 15231654 provenance.
- _6 value "Activation of RET, either by ligand or through specific mutations, results in phosphorylation of multiple tyrosine residues that, in turn, interact with specific adaptor molecules to trigger downstream signaling. Four of the tyrosines phosphorylated on RET activation, tyrosines 905, 1015, 1062, and 1096, have been well characterized, and are known to interact with a number of adaptor molecules to stimulate signaling through phosphatidylinositol kinase (PI3K)/AKT, PLC-gamma, RAS/extracellular signal-regulated kinase (ERK), p38MAPK, JNK and ERK5." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.