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- _6 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _6 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion hadPrimarySource 12869663 provenance.
- _5 wasQuotedFrom 12869663 provenance.
- _5 value "Each apo-ferritin molecule of 450 kDa can sequester up to approximately 4,500 iron atoms (Harrison and Arosio, 1996). Maintenance of low iron pools by increased ferritin levels appears to play a central role in cellular anti-oxidant defense and cytoprotection (Torti and Torti, 2002). In addition, HO-1 is closely associated with cellular iron extrusion mechanisms, which may constitute an alternative cytoprotective mechanism of HO-1 (Snyder and Baranano, 2001). Attenuated HO-1 activity results in decreased cellular iron efflux and subsequently iron overload, whereas HO-1 overexpression accelerates efflux (Poss and Tonegawa, 1997a; Ferris et al., 1999)." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.