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- _6 label "Selventa" provenance.
- _6 comment "support@belframework.org" provenance.
- small_corpus.bel title "BEL Framework Small Corpus Document" provenance.
- small_corpus.bel description "Approximately 2000 hand curated statements drawn from 57 PubMeds." provenance.
- small_corpus.bel version "20131211" provenance.
- small_corpus.bel authoredBy _6 provenance.
- assertion wasDerivedFrom small_corpus.bel provenance.
- assertion wasDerivedFrom _5 provenance.
- assertion hadPrimarySource 11751905 provenance.
- _5 wasQuotedFrom 11751905 provenance.
- _5 value "We have shown recently that Flt-1 VEGFR is expressed in the human MM cell line and patient MM cells and is tyrosine-phosphorylated upon VEGF stimulation (12). Because Flt-1 and the p85 subunit of PI 3-kinase were associated when overexpressed in yeast cells (54), we next determined whether this interaction is biologically significant in MM cells. Flt-1 was immunoprecipitated from VEGF treated and non-treated MM.1S cells followed by immunoblotting with anti-p85 Ab. As illustrated in Fig.5a, p85 is constitutively associated with Flt-1, suggesting that PI 3-kinase participates in Flt-1-mediated VEGF signal transduction." provenance.
- small_corpus.bel license "Creative Commons Attribution-Non-Commercial-ShareAlike 3.0 Unported License" provenance.
- small_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All Rights Reserved." provenance.