Matches in Nanopublications for { ?s ?p ?o <http://www.tkuhn.ch/bel2nanopub/RASoUdDQvkjTgVCtdbsqg8wlq8oY6-lbg8L4Oofg_ksJk#provenance>. }
Showing items 1 to 11 of
11
with 100 items per page.
- _5 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _4 provenance.
- assertion hadPrimarySource 11676474 provenance.
- _4 wasQuotedFrom 11676474 provenance.
- _4 value "u-PA-CAT expressed in combination with dominant negative mutant ERK construct abrogated the Urokinase-type plasminogen activator (uPA) promoter activity in PC3(AR) (AR transfected) cells. ERK dominant negative construct reduced the uPA promoter expression greater than 24-fold. Further, expression of dominant negative vectors PC4raf, CL100, and K97M for the ERK pathway reduced uPA protein expression by 75%, 82% and 57% respectively. This indicates that in MAPK pathway ERK represent a significant component in the regulation of uPA." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.