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- _5 label "Selventa" provenance.
- large_corpus.bel title "BEL Framework Large Corpus Document" provenance.
- large_corpus.bel description "Approximately 61,000 statements." provenance.
- large_corpus.bel version "20131211" provenance.
- large_corpus.bel authoredBy _5 provenance.
- assertion wasDerivedFrom large_corpus.bel provenance.
- assertion wasDerivedFrom _4 provenance.
- assertion hadPrimarySource 10438928 provenance.
- _4 wasQuotedFrom 10438928 provenance.
- _4 value "The combination of the inflammatory cytokines IL-1 beta, TNF-alpha, and IFN-gamma, synergized with Tat to promote the development of angioproliferative KS-like lesions in nude mice that are not observed with each factor alone. Injection of inflammatory cytokines IL-1beta, TNF-alpha and IFN-gamma was found to cause an increase in the expression of bFGF and VEGF. However, bFGF, but not VEGF, synergizes with Tat in vivo and induces endothelial cells to migrate, to adhere, and to grow in response to Tat in vitro. Tat angiogenic effects correlate with the expression of the alpha v beta 3 integrin that is induced by bFGF and binds the arginine-glycine-aspartic acid (RGD) region of Tat." provenance.
- large_corpus.bel rights "Copyright (c) 2011-2012, Selventa. All rights reserved." provenance.